Pharyngeal Carriage of Beta-Haemolytic Streptococcus Species and Seroprevalence of Anti-Streptococcal Antibodies in Children in Bouaké, Côte d'Ivoire.

xlomafota13 shared this article with you from Inoreader Pharyngeal Carriage of Beta-Haemolytic Streptococcus Species and Seroprevalence of Anti-Streptococcal Antibodies in Children in Bouaké, Côte d'Ivoire. Via Laryngologie Related Articles Pharyngeal Carriage of Beta-Haemolytic Streptococcus Species and Seroprevalence of Anti-Streptococcal Antibodies in Children in Bouaké, Côte d'Ivoire. Trop Med Infect Dis. 2020 Nov 27;5(4): Authors: Monemo P, Demba N, Touré FS, Traoré A, Avi C, N'Guessan MA, Tadet JO, Gobey AR, Anoh AE, Diarrassouba A, Tuo MN, Cissé A, Saric J, Utzinger J, Tia H, Kouassi-N'Djeundo J, Becker SL, Akoua-Koffi C Abstract The pharynx of the child may serve as a reservoir of pathogenic bacteria, including beta-haemolytic group A streptococci (GAS), which can give rise to upper airway infections and post-streptococcal diseases. The objective of this study was to determine the prevalence of beta-haemolytic Streptococcus spp. in pharyngeal samples stemming from children aged 3-14 years in Bouaké, central Côte d'Ivoire. Oropharyngeal throat swabs for microbiological culture and venous blood samples to determine the seroprevalence of antistreptolysin O antibodies (ASO) were obtained from 400 children in March 2017. Identification was carried out using conventional bacteriological methods. Serogrouping was performed with a latex agglutination test, while an immunological agglutination assay was employed for ASO titres. The mean age of participating children was 9 years (standard deviation 2.5 years). In total, we detected 190 bacteria in culture, with 109 beta-haemolytic Streptococcus isolates, res ulting in an oropharyngeal carriage rate of 27.2%. Group C streptococci accounted for 82.6% of all isolates, whereas GAS were rarely found (4.6%). The ASO seroprevalence was 17.3%. There was no correlation between serology and prevalence of streptococci (p = 0.722). In conclusion, there is a high pharyngeal carriage rate of non-GAS strains in children from Bouaké, warranting further investigation. PMID: 33261048 [PubMed] View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Comparison of free vascularized iliac bone flap grafting versus pedicled iliac bone flap grafting for treatment of osteonecrosis of the femoral head.

xlomafota13 shared this article with you from Inoreader Comparison of free vascularized iliac bone flap grafting versus pedicled iliac bone flap grafting for treatment of osteonecrosis of the femoral head. Via Journal of plastic, reconstructive & aesthetic surgery : JPRAS Related Articles Comparison of free vascularized iliac bone flap grafting versus pedicled iliac bone flap grafting for treatment of osteonecrosis of the femoral head. J Plast Reconstr Aesthet Surg. 2020 Nov 10;: Authors: Cao Z, Ou Q, Pang X, Wu P, Du W, Tang J Abstract BACKGROUND: A high incidence of osteonecrosis of the femoral head (ONFH), a commonly seen and intractable disease, has been reported. This retrospective study aims to compare the reconstructive outcomes by free vascularized iliac bone flap (FVIBF) with those by vascularized pedicled iliac bone flap (PIBF) to determine which one is better for ONFH patients. METHODS: From January 2010 to December 2017, 35 patients (40 hips) were treated by PIBF grafting, and 32 patients (36 hips) were treated by FVIBF grafting. The two groups were then compared in terms of the preoperative baseline conditions, intraoperative data, and postoperative Harris hip score (HHS). RESULTS: In the PIBF group, the operating time was significantly longer than the FVIBF group (195.5 ± 26.4 vs 147.2 ± 17.7 min, respectively), and the intra-operative blood loss was significantly heavier (330.0 ± 63.9 vs 240.3 ± 37.5 ml, respectively). Meanwhile, the recipient site morbidity rate in the PIBF group outnumbered that in the FVIBF group (27.5% vs 8.3%, respectively), and a higher rate of lateral femoral cutaneous nerve (LFCN) injury was observed in the PIBF group than in the FVIBF group (27.5% vs 8.3%, respectively). No difference was found in postoperative HHS score between the two groups. In both groups, the recovery effect of the patients in stage II was better than that in stage III. CONCLUSION: While maintaining a similar clinical effect, the FVIBF grafting exhibited a distinct advantage over the PIBF grafting, in terms of shorter operative time, less blood loss, and lower risk of LFCN injury. PMID: 33262056 [PubMed - as supplied by publisher] View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Perceptual Voice and Speech Analysis after Supraglottic Laryngeal Closure for Chronic Aspiration in Head and Neck Cancer

xlomafota13 shared this article with you from Inoreader Perceptual Voice and Speech Analysis after Supraglottic Laryngeal Closure for Chronic Aspiration in Head and Neck Cancer Via The Laryngoscope Objectives/Hypothesis To evaluate the voice and speech outcomes after tubed supraglottic laryngeal closure (TSLC) surgery to treat chronic aspiration after radiotherapy for head and neck cancer. Study Design A retrospective case‐control study. Methods The data of patients who underwent radiotherapy for head and neck cancer and who later required total laryngectomy or TSLC for chronic aspiration between 2004 and 2017 were retrieved from a dysphagia clinic. Preoperative and postoperative voice and speech were assessed by the GRBAS and INFVo rating scales. Control subjects who underwent radiotherapy alone or total laryngectomy with a tracheoesophageal prosthesis for other indications were recruited for comparison. Results Of 15 patients who underwent a TSLC with a mean age of 57.3 years (45–75 years), 13 were male and 2 female. All patients had a history of nasopharyngeal carcinoma. The success rate of speech production using their own larynx following an intact TSLC was 64%. There was no statistically significant difference in voice and speech ratings between preoperative and TSLC subjects on the GRBAS (P = .32) and INFVo scales (P = .57), although the quality of voice appeared to deteriorate after TSLC. However, the INFVo scale for impression, intelligibility and unsteadiness of the voice after TSLC was statistically significantly better than for laryngectomy with tracheoesophageal speech. Conclusions A tubed supraglottic laryngeal closure controls chronic aspiration while preserving the larynx for phonation, and results in a better voice and speech quality than a laryngectomy with a voice prosthesis. Level of Evidence 4 Laryngoscope, 2020 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

The Effect of Anti-Amoebic Agents and Ce6-PDT on Acanthamoeba castellanii Trophozoites and Cysts, In Vitro.

xlomafota13 shared this article with you from Inoreader The Effect of Anti-Amoebic Agents and Ce6-PDT on Acanthamoeba castellanii Trophozoites and Cysts, In Vitro. Via radioactive iodine Related Articles The Effect of Anti-Amoebic Agents and Ce6-PDT on Acanthamoeba castellanii Trophozoites and Cysts, In Vitro. Transl Vis Sci Technol. 2020 Nov;9(12):29 Authors: Shi L, Muthukumar V, Stachon T, Latta L, Elhawy MI, Gunaratnam G, Orosz E, Seitz B, Kiderlen AF, Bischoff M, Szentmáry N Abstract Purpose: The purpose of this study was to analyze the concentration-dependent effects of biguanides (polyhexamethylene biguanide [PHMB], chlorhexidine [CH]); diamidines (hexamidine-diisethionate [HD], propamidine-isethionate [PD], dibromopropamidine-diisethionate [DD]); natamycin (NM); miltefosine (MF); povidone iodine (PVPI), and chlorin e6 PDT on Acanthamoeba trophozoites and cysts, in vitro. Methods: Strain 1BU was cultured in peptone-yeast extract-glucose medium. Trophozoites or cysts were cultured in PYG medium containing each agent at 100%, 50%, and 25% of maximum concentration for 2 hours. The percentage of dead trophozoites was determined using a non-radioactive cytotoxicity assay and trypan blue staining. Treated cysts were also maintained on non-nutrient agar Escherichia coli (E. coli) plates and observed for 3 weeks. Results: All tested drugs displayed significant cytotoxic effects on 1BU cells based on the biochemical and staining-based viability assays tested. On non-nutrient agar E. coli plates, neither trophozoites nor freshly formed cysts were observed after PHMB, PD, NM, and PVPI treatment, respectively, within 3 weeks. However, CH-, HD-, DD-, and MF-treated cysts could excyst, multiply, and encyst again. Conclusions: The off-label drugs PHMB, PD, NM, and PVPI are under in vitro conditions more effective against strain 1BU than CH, HD, DD, and MF. Our findings also suggest that the non-nutrient agar E. coli plate assay should be considered as method of choice for the in vitro analysis of the treatment efficacy of anti-amoebic agents. Translational Relevance: Ophthalmologists may optimize the treatment regime against Acanthamoeba keratitis by pre-testing the in vitro susceptibilities of the Acanthamoeba strain against drugs of interest with the non-nutrient E. coli agar plate assay. PMID: 33262903 [PubMed] View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Admission avoidance in tonsillitis and peritonsillar abscess: a prospective national audit during the initial peak of the COVID‐19 pandemic

xlomafota13 shared this article with you from Inoreader Admission avoidance in tonsillitis and peritonsillar abscess: a prospective national audit during the initial peak of the COVID‐19 pandemic Via Clinical Otolaryngology Abstract Objectives To report changes in practice brought about by COVID‐19 and the implementation of new guidelines for the management of tonsillitis and peritonsillar abscess (PTA), and to explore factors relating to unscheduled re‐presentations for patients discharged from the emergency department (ED). Design Prospective multicentre national audit over 12 weeks from 6th April 2020. Setting UK secondary care ENT departments. Participants Adult patients with acute tonsillitis or PTA. Main outcome measures Re‐presentation within 10 days for patients discharged from the ED. Results 83 centres submitted 765 tonsillitis and 416 PTA cases. 54.4% (n=410) of tonsillitis and 45.3% (187/413) of PTAs were discharged from ED. 9.6% (39/408) of tonsillitis and 10.3% (19/184) of PTA discharges re‐presented within 10 days, compared to 9.7% (33/341) and 10.6% (24/224) for those admitted from ED. The subsequent admission rate of those initially discharged from ED was 4.7% for tonsillitis and 3.3% for PTAs. IV steroids and antibiotics increased the percentage of patients able to swallow from 35.8% to 72.5% for tonsillitis (n=270/754 and 441/608) and from 22.3% to 71.0% for PTA (n=92/413 and 265/373). 77.2% of PTAs underwent drainage (n=319/413), with no significant difference in re‐presentations in those drained vs not‐drained (10.6% vs 9.5%, n=15/142 vs 4/42, p=0.846). Univariable logistic regression showed no significant predictors of re‐presentation within 10 days. Conclusions Management of tonsillitis and PTA changed during the initial peak of the pandemic, shifting towards outpatient care. Some patients who may previously have been admitted to hospital may be safely discharged from the ED. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Laryngeal Pathologies Associated with the Genre of Singing and Professional Singing Status in a Treatment‐Seeking Population

xlomafota13 shared this article with you from Inoreader Laryngeal Pathologies Associated with the Genre of Singing and Professional Singing Status in a Treatment‐Seeking Population Via The Laryngoscope Objectives/Hypothesis Singers have high vocal demands and are at increased risk of developing voice disorders. Different singing genres place different technical demands on the voice. However, differences in laryngeal pathology based on genre have not been well‐researched. The purpose of this study was to determine the prevalence of laryngeal pathology in different genres of professional and amateur singers who present with a voice complaint. Study Design Retrospective review. Methods Retrospective review of patients seen at a tertiary laryngology practice. Self‐identified singers who reported their primary singing genre and categorized their singing as a full‐time job, part‐time job, or amateur involvement were included. Type and prevalence of pathology were calculated based on genre and professional status. Results Of the 302 self‐identified singers, 54% (n = 164) had laryngeal pathology. Among those with pathology, the most common finding was fibrotic lesion (38.4%, 63/164). Genres in which a majority of singers had pathology were other (69.2%, 9/13), choral (64.7%, 11/17), pop (63.2%, 12/19), musical theater (61.4%, 43/70), country (100%, 4/4), and Latin (100%, 2/2). The highest prevalence of pathology was seen in part‐time professional singers (62.2%, 41/66) and full‐time professionals (60.8%, 62/102), compared to amateurs (45.1%, 60/133). Conclusions Laryngeal pathology is prevalent in singers presenting with a voice complaint. Regardless of genre or professional status, fibrotic lesions were the most common pathological finding. This study provides preliminary data on the prevalence of different laryngeal pathologies found in singers by genre and degree of professional involvement. Level of Evidence 4 Laryngoscope, 2020 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Laryngeal sarcoidosis

xlomafota13 shared this article with you from Inoreader Laryngeal sarcoidosis at a tertiary airway centre: Our experience with 32 patients Via Clinical Otolaryngology Abstract Figure 2. Endoscopic photograph of laryngeal sarcoidosis and its management. A) Intraoperative photograph of larynx prior to intervention, demonstrating a thickened epiglottis, arytenoid mucosa, false vocal folds, as well as tightening of the aryepiglottic folds, particularly the left. B) Intraoperative photograph after intervention, which involved pepper pot technique to epiglottis and arytenoid mucosa, as well as division of left aryepiglottic fold and bilateral false vocal folds. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Impact of the COVID-19 Pandemic on Immunomodulatory and Immunosuppressive Therapies in Dermatology: Patient and Physician Attitudes in Argentina

xloma.fota.13 shared this article with you from Inoreader Impact of the COVID-19 Pandemic on Immunomodulatory and Immunosuppressive Therapies in Dermatology: Patient and Physician Attitudes in Argentina Via Actas Dermo-Sifiliográficas S. Zimman, M.J. Cura, P.C. Lun, C.M. Echeverría, L.D. Mazzuoccol Actas Dermosifiliogr. 2020;111:806-7 Full Text - PDF View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Eosinophilic Panniculitis Associated With COVID-19

xloma.fota.13 shared this article with you from Inoreader Eosinophilic Panniculitis Associated With COVID-19 Via Actas Dermo-Sifiliográficas V.M. Leis-Dosil, A. Sáez Vicente, M.M. Lorido-Cortés Actas Dermosifiliogr. 2020;111:804-5 Full Text - PDF View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Managing Psoriasis Consultations During the COVID-19 Pandemic: Recommendations From the Psoriasis Group of the Spanish Academy of Dermatology and Venereology (AEDV)

xloma.fota.13 shared this article with you from Inoreader Managing Psoriasis Consultations During the COVID-19 Pandemic: Recommendations From the Psoriasis Group of the Spanish Academy of Dermatology and Venereology (AEDV) Via Actas Dermo-Sifiliográficas I. Belinchón, L. Puig, L. Ferrándiz, P. de la Cueva, J.M. Carrascosa Actas Dermosifiliogr. 2020;111:802-4 Full Text - PDF View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Recommendations on Sun Exposure and Photoprotection Following Easing of the COVID19 Pandemic Lockdown: Spanish Photobiology Group of the Spanish Academy of Dermatology and Venerology (AEDV)

xloma.fota.13 shared this article with you from Inoreader Recommendations on Sun Exposure and Photoprotection Following Easing of the COVID19 Pandemic Lockdown: Spanish Photobiology Group of the Spanish Academy of Dermatology and Venerology (AEDV) Via Actas Dermo-Sifiliográficas J. Aguilera, M.V. de Gálvez, P. Aguilera, M. de Troya-Martín, Y. Gilaberte Actas Dermosifiliogr. 2020;111:799-801 Full Text - PDF View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Cutaneous Polyarteritis Nodosa in a Patient with Ulcerative Colitis

xloma.fota.13 shared this article with you from Inoreader Cutaneous Polyarteritis Nodosa in a Patient with Ulcerative Colitis Via Actas Dermo-Sifiliográficas T. Hiraiwa, T. Yamamoto Actas Dermosifiliogr. 2020;111:796-8 Full Text - PDF View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.