Single‐retainer all‐ceramic resin‐bonded fixed dental prostheses: Long‐term outcomes in the esthetic zone

alexandrossfakianakis shared this article with you from Inoreader Single‐retainer all‐ceramic resin‐bonded fixed dental prostheses: Long‐term outcomes in the esthetic zone via Journal of Esthetic and Restorative Dentistry Abstract Objectives To present an update on the concept of cantilevered single-retainer all-ceramic resin-bonded fixed dental prostheses (RBFDPs) first presented 25 years ago in the Journal of Esthetic Dentistry. Overview The initially presented case of the concept was followed clinically over 26 years and is presented along with two additional clinical long-term cases using varying methods to obtain an esthetic and hygienic ovate pontic design. Veneered alumina and zirconia ceramic (3 mol% yttria–tetragonal zirconia polycrystalline ceramic; 3Y-TZP) was used and bonded with a phosphate monomer containing luting resin after 50 μm alumina particle air-abrasion at 0.25 MPa pressure. The restorations replacing incisors did not debond and soft tissues in the pontic area were maintained over 26 years. Conclusions Cantilevered single-retainer all-ceramic RBFDPs today made from veneered 3Y-TZP zirconia ceramic can be considered a standard of care for the replacement of single incisors and provide an excellent esthetic outcome with a long-term preservation of soft tissues in the pontic area. Clinical Significance Bonding nonretentive oxides ceramics such as alumina and zirconia ceramic with phosphate monomer containing luting resins after alumina particle air-abrasion is durable over decades. This proves that bonding to zirconia ceramic is not of any problem when adequate methods are used. Single-retainer zirconia ceramic RBFDPs maintain soft tissues in the edentulous area of single missing incisors and often deem implants unessential for this indication. View on Web

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Soft tissue esthetics around immediately provisionalized delayed implants with and without connective tissue graft: A randomized clinical trial pilot study

alexandrossfakianakis shared this article with you from Inoreader Soft tissue esthetics around immediately provisionalized delayed implants with and without connective tissue graft: A randomized clinical trial pilot study via Clinical Implant Dentistry and Related Research Abstract Objective Evaluate the peri-implant soft tissue esthetics following a single, immediately provisionalized, delayed implant with/-out subepithelial connective tissue graft (SCTG). Material and Methods The eligible patients were randomized into two groups. Immediate provisionalization was performed with (test group: SCTGG) or without SCTG (control group: NGG). The soft tissue esthetics was assessed by Pink Esthetic Score (PES) and Mucosal Scarring Index (MSI), at 6 and 12 months, following final implant restoration. Results The SCTGG, compared to NGG, yielded a 0.2 increased PES at 12 months (95% confidence interval (CI): −1, 1.4) and a 0.2 decreased MSI score (95% CI −0.9, 0.5) with no statistically significant differences in PES and MSI between both groups (p > 0.05). Conclusion Soft tissue grafting around immediately provisionalized delayed implants could exhibit comparable results to immediate provisionalization alone in terms of peri-implant soft tissue esthetics using PES and MSI (ClinicalTrials.gov Identifier: NCT03770975). View on Web

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Neurotization of the radial forearm free flap improves swallowing outcomes in hemiglossectomy defects

alexandrossfakianakis shared this article with you from Inoreader Neurotization of the radial forearm free flap improves swallowing outcomes in hemiglossectomy defects via Head & Neck Abstract Background We examined the effect of free tissue neurotization on speech and swallowing outcomes for patients undergoing reconstruction of hemiglossectomy defects with a radial forearm free flap (RFFF). Methods A retrospective study was performed in patients with oral cavity squamous cell carcinoma undergoing a hemiglossectomy and reconstruction with a RFFF. Functional outcomes including nutritional mode, range of liquids and solids, and speech understandability were analyzed 1-year post-treatment. Results Eighty-four patients were included in this analysis, 41 of whom had neurotized flaps (49%). No significant differences in demographic or clinical variables were seen between the neurotized and non-neurotized groups. On multivariate analysis controlling for BMI, flap area, and N-classification, patients with neurotized flaps were significantly more likely to have normal range of liquids and solids and less likely to have a G-tube. Conclusions Neurotization of RFFF reconstructing hemiglossectomy defects results in decreased G-tube dependence and improved range of liquids and solids. View on Web

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Role of mechano-sensitive non-coding RNAs in bone remodeling of orthodontic tooth movement: recent advances

alexandrossfakianakis shared this article with you from Inoreader Role of mechano-sensitive non-coding RNAs in bone remodeling of orthodontic tooth movement: recent advances via Progress in Orthodontics - Latest Articles Orthodontic tooth movement relies on bone remodeling and periodontal tissue regeneration in response to the complicated mechanical cues on the compressive and tensive side. In general, mechanical stimulus regu... View on Web

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Managing Oromandibular Hardware Failure after Free Flap Surgery

alexandrossfakianakis shared this article with you from Inoreader Managing Oromandibular Hardware Failure after Free Flap Surgery via Seminars in Plastic Surgery Semin Plast Surg DOI: 10.1055/s-0042-1760289 Hardware failure after oromandibular reconstruction using free tissue transfer can delay additional therapies directed at cancer treatment and prevent patients from returning to normal oral function. Understanding and strict adherence to principles of rigid fixation is critical in preventing complications. Early surgical intervention for hardware exposure as well as utilization of locoregional flaps may prevent the need for more ex tensive revision surgery. [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USA Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text View on Web

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Stereotactic Partial Breast Irradiation: What Does the Future Hold?

alexandrossfakianakis shared this article with you from Inoreader Stereotactic Partial Breast Irradiation: What Does the Future Hold? via American Journal of Clinical Oncology - Current Issue Breast irradiation has evolved significantly over the last several decades. Accelerated partial breast and stereotactic breast irradiation have evolved as strategies to reduce irradiated volumes, preserve appropriate oncologic control, and improve cosmetic outcome. The sequencing and/or combination of stereotactic partial breast irradiation with novel systemic agents is of great interest to the oncologic community. Here we explore the landscape of modern trials and opine on the future of partial breast irradiation. View on Web

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Weekly Symptom Profiles of Non‐hospitalized Individuals Infected with SARS‐CoV‐2 During the Omicron Outbreak in Hong Kong: A Retrospective Observational Study from a Telemedicine Centre

alexandrossfakianakis shared this article with you from Inoreader Weekly Symptom Profiles of Non‐hospitalized Individuals Infected with SARS‐CoV‐2 During the Omicron Outbreak in Hong Kong: A Retrospective Observational Study from a Telemedicine Centre via Journal of Medical Virology Abstract Background Omicron BA.2.2 is the dominant variant in Hong Kong outbreak since December-31 2021. There is no study reporting the weekly symptom profile after infection. Methods In this retrospective study, participants who tested positive for SARS-CoV-2 after December-31 2021 and registered in the telemedicine system between March 14-May 6 2022 were analysed. Findings Among registered 12950 self-quarantined COVID-19 positive patients, 11776 symptomatic patients were included for weekly symptom profile analysis. 4718 (40.1%) patients reported symptoms in the first week after positive test, 2501 (21.2%) in the second week, 1498 (12.7%) in the third week, 1048 (8.9%) in the fourth week, and 2011 (17.1%) in over four weeks. Cough was the most common symptom in all participants. Patients in the first week had higher odds of reporting fever (0.206, 95% CI 0.161-0.263, p<0.001) and sore throat (0.228, 95% CI 0.208-0.252, p<0.001). Patients in over 4 weeks had a higher odds of reporting fatigue (1.263, 95% CI 1.139-1.402, p<0.001). Further, having at least two vaccine doses linked to lower odds of having fever (0.675, 95% CI 0.562-0.811, p<0.001), but not associated with the presence of cough and fatigue. Diabetic patients had higher odds of reporting diarrhea (1.637, 95% CI 1.351-1.982, p<0.001). Conclusion Symptoms from omicron infection may last for more than four weeks and symptom profiles vary from week to week. Vaccination and comorbidity affect the symptom profiles. This article is protected by copyright. All rights reserved. View on Web

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Outpatient parotidectomy with or without the use of a post‐operative drain: a retrospective bi‐institutional study

alexandrossfakianakis shared this article with you from Inoreader Outpatient parotidectomy with or without the use of a post‐operative drain: a retrospective bi‐institutional study via Clinical Otolaryngology Abstract Objective Parotid surgery is historically performed as an inpatient procedure and suctions drains are predominantly used during surgery. Recent literature provides evidence that outpatient parotid surgery is safe and effective. Our study aims to describe the results of drainless outpatient parotidectomy and outpatient parotidectomy with drain placement and compare their outcomes. Design Retrospective cohort study Participants Patients that underwent outpatient drain-less parotidectomy and patients that underwent outpatient parotidectomy with post-operative drain placement. Results Three hundred eighty patients underwent outpatient parotidectomy with drain placement and 31 patients underwent outpatient drainless parotidectomy in two different hospitals. The incidence of hematoma (drain: 3.1% vs. drainless: 0%, p=1), infection (drain: 14.3% vs. drainless: 13.8%, p=1), and salivary fistula (drain: 5.6% vs. drainless: 3.4, p=1) were comparable between both groups. Seroma or sialocele was more frequently seen in the drain-less group (27.6% vs. 6.2%, p<0.001), but were all managed conservatively. Within ten days after surgery, unplanned visits seemed more frequent in the drain group, although the difference was not statistically significant (14.9% vs. 3.4%, p=0.16). Conclusions Outpatient parotid surgery with or without the use of a post-operative drain is safe, practical, and feasible. Same-day discharge with and without drain placement yield comparable outcomes. However, the results need to be interpreted cautiously as this study was limited by a small cohort of parotidectomies without drain placement. Future studies should further compare both approaches. View on Web

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H‐Type Tracheoesophageal Fistula Cannulation for Rapid Intraoperative Localization

alexandrossfakianakis shared this article with you from Inoreader H‐Type Tracheoesophageal Fistula Cannulation for Rapid Intraoperative Localization via The Laryngoscope Various techniques for tracheoesophageal fistula cannulation have been reported. In this case, we created a loop using a plastic catheter. The loop allowed us to create traction for rapid intraoperative localization and to pull a difficult-to-reach fistula, superiorly into the neck, to be reached through a cervical approach. Laryngoscope, 2022 View on Web

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Prognostic significance of head and neck spindle cell carcinoma

alexandrossfakianakis shared this article with you from Inoreader Prognostic significance of head and neck spindle cell carcinoma via Head & Neck Abstract Background Our study investigates the prognostic significance of spindle cell histology on overall survival (OS) of conventional head and neck squamous cell carcinoma (HNSCC). Methods The 2004 to 2017 National Cancer Database was queried for patients with head and neck spindle cell carcinoma (HNSpCC) (n = 1572) or HNSCC (n = 242 697) of the oral cavity, major salivary glands, sinonasal tract, oropharynx, hypopharynx, and larynx treated with curative intent. Results Patients with HNSpCC presented more frequently with higher-grade tumors and cN0 disease than those with HNSCC (p < 0.001). In the oral cavity, the HR for death for SpCC compared with SCC was 1.33 (p < 0.001). In the oropharynx, the HR for death for SpCC compared with SCC was 1.47 (p = 0.028). Conclusions After adjusting for patient, tumor, and treatment characteristics, SpCC histology had an independent adverse prognostic effect on OS in the oral cavity and oropharynx. SpCC histology does not necessarily portend poorer survival in all HNSCC. Level of Evidence: 4. View on Web

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Clinical evaluation and patient related outcomes of one‐ and two‐piece zirconia implants at five years of loading: A case series study

alexandrossfakianakis shared this article with you from Inoreader Clinical evaluation and patient related outcomes of one‐ and two‐piece zirconia implants at five years of loading: A case series study via Journal of Esthetic and Restorative Dentistry Abstract Objective The objective of this study was to investigate the survival and biological and mechanical complications of one-piece and two-piece zirconia implants at five years of loading. Materials and Methods Consecutive patients receiving zirconia implants were studied, collecting data at five years of loading on their clinical history, peri-implant health status, mechanical complications, esthetic results, and patient related outcomes. Results The study included 18 patients with 29 implants. The survival rate was 86% in implant-based analysis and 78% in patient-based analysis. There were no cases of peri-implantitis, but mucositis was present in 53% of implants. A mean of 4.1 ± 0.81 mm was obtained for probing depth and 1.6 ± 0.9 mm for crestal bone loss (radiographic assessment). There were no implant fractures. Major (10%) and minor (10%) prosthesis complications were observed. The esthetic outcome was moderate to almost perfect, with a high level of patient satisfaction. No significant association was found between survival rate and the presence of mucositis around one- or two-piece implants or any other study variable. Conclusions The survival rate is low for one- and two-piece zirconia implants. Both types of implants demonstrated a low mechanical complication rate. The incidence of periimplantitis is low but mucositis is present in 50%. Patient satisfaction related to esthetics and function is moderate to high. They represent a good option for patients requiring an alternative to titanium implants. Clinical Relevance Zirconia implants appear to be an alternative to the titanium option and may be indicated for patients requiring "metal-free" restorations. View on Web

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