Measurement of three‐dimensional changes in lip vermilion in adult female patients after orthodontic extraction: a retrospective longitudinal study

xlomafota13 shared this article with you from Inoreader Measurement of three‐dimensional changes in lip vermilion in adult female patients after orthodontic extraction: a retrospective longitudinal study Via Head & Face Medicine 3D facial scanning has changed the way facial aesthetic is evaluated and has numerous advantages for facial analysis. The specific relationship between lip vermilion morphological changes after orthodontic ext... View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Familial Risk of Hashimoto's Thyroiditis Among First-Degree Relatives: A Population-Based Study in Korea

xlomafota13 shared this article with you from Inoreader Familial Risk of Hashimoto's Thyroiditis Among First-Degree Relatives: A Population-Based Study in Korea Via liebertpub1 Thyroid, Ahead of Print. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Surgical Landmarks for Parapharyngeal Internal Carotid Artery During Extended Endoscopic Surgery of Nasopharynx: A Cadaveric and Radiological Study

xlomafota13 shared this article with you from Inoreader Surgical Landmarks for Parapharyngeal Internal Carotid Artery During Extended Endoscopic Surgery of Nasopharynx: A Cadaveric and Radiological Study Via Otolaryngology Indian Abstract Nasopharynx is a complex region situated at the center of skull surrounded by various vital neurovascular structures. Surgical access to the nasopharyngeal space poses significant challenges due to the position of the internal carotid artery (ICA). Open approaches to nasopharynx utilize the lateral to medial anatomy but the endoscopic endo-nasal approach warrants knowledge about the medial to lateral anatomy. In this study we attempted to find the consistent surgical landmarks for parapharyngeal portion of internal carotid artery at the level of nasopharynx by means of cadaveric and radiological study. Eight fresh frozen cadavers (16 sides) and 30 CT angiography (60 sides) were included in the anatomical and radiological study respectively. Superior aspect of the torus tubarius was taken as the reference point in cadaveric study and C1–C2 interspace was used as the reference point for the radiological study. The distance between the ICA to the landmarks such as fossa of Rosenmullaer, torus tubarius, medial and lateral pterygoid plates were recorded. The mean distance of ICA to the fossa of Rosenmuller was 8.5 ± 1.4 mm and 9.1 ± 1.1 mm in the cadaveric and radiological study respectively. The mean distance between ICA to torus tubarius was 19.8 ± 1.3 mm in cadaveric and 20.6 ± 1.0 mm in radiological study. The mean distance of ICA to medial and lateral pterygoid plates were 25.3 ± 1.4 mm and 18.2 ± 1.4 mm in the cadaveric study and 25.9 ± 1.2 mm and 18.8 ± 1.3 mm in the radiological study respectively. On correlating the measurements between cadaveric and radiological study, the p values were not statistically significant (p > 0.05). The closest landmark to the ICA was the fossa of Rosenmuller. ICA was located at the same sagittal plane as that of the lateral pterygoid plate. The nasopharynx is a complex anatomical region closely relate d to ICA. Inadvertent injury to ICA is one of the dreaded complications of nasopharyngeal surgery. Fossa of Rosenmuller is only few millimeters away from the ICA and must be treated very cautiously. During the endoscopic approach, the ICA is at the sagittal plane as of the lateral pterygoid plate. This must be kept in mind when advancing toward the ICA by keeping intact the lateral pterygoid plate when possible and one should stay in the plane of medial pterygoid plate as the ICA lies posterolateral to it. Cadaveric dissections supported by radiological data would definitely aid surgeons to successfully perform surgeries in nasopharynx. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

The Impact of Neuronavigation on the Surgical Outcome of Microvascular Decompression for Trigeminal Neuralgia

xlomafota13 shared this article with you from Inoreader The Impact of Neuronavigation on the Surgical Outcome of Microvascular Decompression for Trigeminal Neuralgia Via leak of cerebrospinal fluid World Neurosurg. 2021 Feb 20;149:80-85. doi: 10.1016/j.wneu.2021.02.063. Online ahead of print. ABSTRACT OBJECTIVE: Microvascular decompression (MVD) is considered the only etiological treatment for drug-resistant trigeminal neuralgia (TN). Nonetheless, despite the recent technological advances, the risks associated with MVD remain non-negligible. The aim of this study was to evaluate the impact of using neuronavigation on the surgical outcomes of patients with TN submitted for MVD. METHODS: We analyzed 30 consecutive patients (11 men, 19 women) who underwent MVD for TN between January 2019 and December 2019. Patients were divided in 2 groups according to the use of neuronavigation (group A: MVD with neuronavigation; group B: MVD without neuronavigation). The impact of neuronavigation was assessed on the following parameters: craniotomy size, surgical duration, mastoid air cell opening, postoperative cerebrospinal fluid (CSF) leakage an d other complications occurrence, and length of hospitalization. The acute pain relief and the Barrow Neurological Institute score at follow-up were used to evaluate the functional outcome. RESULTS: The craniotomy size, the surgical duration, and the CSF leak incidence were significantly reduced in group A compared with group B (P = 0.0009, P = 0.0369, and P = 0.0406, respectively). The incidence of mastoid air cell opening, and the length of hospitalization were reduced in group A compared with group B, although these differences were not statistically significant. We obtained an acute pain relief in all cases, and the Barrow Neurological Institute score at follow-up was significantly reduced (P < 0.0001). CONCLUSIONS: Neuronavigation is a useful tool that significantly reduced craniotomy size, surgical duration, and CSF leak incidence in patients with TN submitted for MVD. We advise to routinely implement neuronavigation in this type of surgery. PMID:33621673 | DOI:10.1016/j.wneu.2021.02.063 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Recurrent Facial Paralysis—an Unusual Initial Presentation of Temporal Bone Metastasis in Case of Advanced Prostate Malignancy

xlomafota13 shared this article with you from Inoreader Recurrent Facial Paralysis—an Unusual Initial Presentation of Temporal Bone Metastasis in Case of Advanced Prostate Malignancy Via Otolaryngology Indian Abstract Metastasis into temporal bone is uncommon. Involvement of facial nerve is rarer. We report an unusual case of metastatic prostatic carcinoma presenting initially as facial nerve palsy in an 82 year old male. Diagnostic pitfalls have been discussed. Radiological evaluation followed by biopsy was diagnostic. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Phonation Resistance Training Exercises (PhoRTE) With and Without Expiratory Muscle Strength Training (EMST) For Patients With Presbyphonia: A Noninferiority Randomized Clinical Trial

xlomafota13 shared this article with you from Inoreader Phonation Resistance Training Exercises (PhoRTE) With and Without Expiratory Muscle Strength Training (EMST) For Patients With Presbyphonia: A Noninferiority Randomized Clinical Trial Via swallowing exercises J Voice. 2021 Mar 16:S0892-1997(21)00077-1. doi: 10.1016/j.jvoice.2021.02.015. Online ahead of print. ABSTRACT OBJECTIVES: Presbyphonia negatively impacts quality of life in patients with age-related voice changes. A proof-of-concept study showed promise for high vocal intensity exercise to treat presbyphonia, which became the basis for a novel intervention for age-related voice changes known as Phonation Resistance Training Exercises (PhoRTE). Expiratory Muscle Strength Training ( EMST) has also been proposed as an additional intervention to target and strengthen the aging respiratory system; however, EMST has undergone limited evaluation as an adjunct treatment for elderly patients undergoing voice therapy for presbyphonia. This study determined if the addition of EMST to PhoRTE voice therapy (PhoRTE + EMST) is at least as effective at voice improvement as PhoRTE alone. STUDY DESIGN: Prospective, randomized, controlled, single-blinded, non-inferiority. MATERIALS AND METHODS: Participants aged 55 years or older with a diagnosis of vocal fold atrophy were randomized to complete PhoRTE therapy or PhoRTE + EMST. The primary outcome was change in Voice Handicap Index-10 (VHI-10). Secondary outcomes included the Aging Voice Index, maximum expiratory pressure, and acoustic and aerodynamic measures of voice. Repeated measures linear mixed models were constructed to analyze outcomes at a significance level of α = 0.10. RESULTS: Twenty-six participa nts were recruited for the study, and 24 participants were randomized to either treatment arm. Sixteen participants completed the entire study. Both treatment arms showed statistically significant and clinically meaningful improvements in VHI-10 (PhoRTE mean [M] = -8.20, P < 0.001; PhoRTE + EMST M = -9.58, P < 0.001), and PhoRTE + EMST was noninferior to PhoRTE alone (P = 0.069). Both groups experienced a statistically significant pre-post treatment decrease (improvement) in AVI scores (PhoRTE M = -18.40, P = 0.004; PhoRTE + EMST M = -16.28, P = 0.005). PhoRTE+EMST had statistically significantly greater changes in maximum expiratory pressure compared to PhoRTE alone (PhoRTE M = 8.24 cm H2O, PhoRTE + EMST M = 32.63 cm H2O; P= 0.015). Some secondary acoustic and aerodynamic outcomes displayed trends toward improvement. CONCLUSION: This study demonstrates that voice therapy targeting high vocal intensity exercise (eg, PhoRTE) and EMST can play a role in improving voice outcomes for patients with presbyphonia. PMID:33741235 | DOI:10.1016/j.jvoice.2021.02.015 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

We must respect the anti-SARS-CoV-2 vaccine schedule without delay in cancer patients under treatment

xlomafota13 shared this article with you from Inoreader We must respect the anti-SARS-CoV-2 vaccine schedule without delay in cancer patients under treatment Via Association française pour l'étude du cancer Bull Cancer. 2021 Mar 5:S0007-4551(21)00073-4. doi: 10.1016/j.bulcan.2021.02.003. Online ahead of print. NO ABSTRACT PMID:33741139 | DOI:10.1016/j.bulcan.2021.02.003 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Tumor-host interface in oral squamous cell carcinoma: Impact on nodal metastasis and prognosis

xlomafota13 shared this article with you from Inoreader Tumor-host interface in oral squamous cell carcinoma: Impact on nodal metastasis and prognosis Via http://link.springer.com/journal/405,European archives of oto-rhino-laryngology,The European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino Eur Arch Otorhinolaryngol. 2021 Mar 20. doi: 10.1007/s00405-021-06756-y. Online ahead of print. ABSTRACT PURPOSE: To evaluate tumor-host interface in oral squamous cell carcinoma (OSCC) by the Brandwein-Gensler histological risk score (BG risk score); to assess its association with clinicopathological features and impact on survival outcomes in a contemporary cohort staged as per AJCC 8th edition pTNM classification. METHODS: This retrospective cohort study at a tertiary care centre included 178 cases of OSCC treated by primary surgical resection from 2013 to 2016. Pathological lymph node status, disease-free survival (DFS), overall survival (OS) were assessed. RESULTS: BG risk score assessment categorized 25 (14%) cases as low-risk, 93 (52%) as intermediate-risk, and 60 (34%) as high-risk. BG risk score category progression from low to intermediate to high risk was associated with an incremental risk of worsening pN status , DFS, and OS. BG risk score categories significantly demarcated 2-year DFS (96% in low-risk, 51.6% in intermediate-risk, 15% in high-risk; p < 0.001) and OS (96% in low-risk, 66.7% in intermediate-risk, 31.3% in high-risk; p < 0.001). On stratified analysis, BG risk score could further demarcate prognosis in early (I/II) and late (III/IV) stage subgroups (p < 0.001). Multivariate analysis indicated the prognostic impact of BG risk score categories to be additional to, and of equal magnitude to, impact of pTNM stage. CONCLUSIONS: BG risk score is a powerful prognostic tool in OSCC additional to pTNM staging. It can enable risk stratification and inform decisions regarding post-surgical adjuvant treatment. It is undertaken with routine histopathological evaluation, with no increased expense or turnaround time. A case is made for its inclusion in OSCC reporting guidelines. PMID:33743065 | DOI:10.1007/s00405-021-06756-y View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Prevalence and pubo-umbilical index of pyramidalis muscle in a select Kenyan population

xlomafota13 shared this article with you from Inoreader Prevalence and pubo-umbilical index of pyramidalis muscle in a select Kenyan population Via radiol anat Surg Radiol Anat. 2021 Mar 20. doi: 10.1007/s00276-021-02733-6. Online ahead of print. ABSTRACT PURPOSE: Pyramidalis is a lower anterior abdominal wall muscle that is considered vestigial and shows variations in prevalence and size. It's been utilized as an anatomical landmark and harvested for use in various surgical procedures. Despite knowledge of its clinical importance, data on the prevalence of pyramidalis remain absent from the Kenyan population with few studies globa lly reporting on its pubo-umbilical index. We therefore aimed to determine the prevalence and relative lengths (pubo-umbilical index) of pyramidalis muscle in a sample Kenyan population. MATERIALS AND METHODS: Fifty-two cadavers (41 males, 11 females) from the Department of Human Anatomy, University of Nairobi were used. Prevalence and length of the muscle (l) were established, and the distance between pubic symphysis and umbilicus (L) measured and used to calculate pubo-umbilical index (l/L ×100%). Independent and paired T tests were done, using SPSS® version 22. A p value of ≤ 0.05 was considered statistically significant at a 95% confidence interval. RESULTS: Pyramidalis was present in 84% (44) of cadavers; 83% (43) bilaterally, 2% (1) unilaterally, and 85.4% (35) in males, 81.8% (9) in females. Mean length in males and females was 71.8 ± 35 mm and 63.5 ± 37.5 mm, respectively. Mean pubo-umbilical index was 38% ± 18 (39 % ± 18 males, 35% ± 19 females). No sta tistically significant difference was found. CONCLUSION: Pyramidalis is a highly prevalent muscle in the Kenyan population and, hence, could be exploited for its clinical and surgical utilities. The muscle terminates largely within the 2nd quarter (25-50%) of the infra-umbilical linea alba measured from pubic symphysis. Its pubo-umbilical index would be useful to surgeons making midline infra-umbilical incisions and performing procedures involving the muscle. PMID:33743034 | DOI:10.1007/s00276-021-02733-6 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Propranolol versus nadolol for treatment of pediatric subglottic hemangioma,,,,,Nadolol is a non-selective β-adrenergic antagonist that lacks intrinsic sympathomimetic activity and membrane-stabilizing properties. Nadolol is two to four times more potent than propranolol. The drug reduces IOP when administered topically in a concentration of 0.3–2%160 or orally in a dose of 20–40 mg. Nadolol - an overview | ScienceDirect Topicswww.sciencedirect.com › topics › neuroscience › nadolol

xlomafota13 shared this article with you from Inoreader Message: Nadolol is a non-selective β-adrenergic antagonist that lacks intrinsic sympathomimetic activity and membrane-stabilizing properties. Nadolol is two to four times more potent than propranolol. The drug reduces IOP when administered topically in a concentration of 0.3–2%160 or orally in a dose of 20–40 mg. Nadolol - an overview | ScienceDirect Topicswww.sciencedirect.com › topics › neuroscience › nadolol Propranolol versus nadolol for treatment of pediatric subglottic hemangioma Via International Journal of Pediatric Otorhinolaryngology Publication date: Available online 21 March 2021 Source: International Journal of Pediatric Otorhinolaryngology Author(s): Weining Yang, Nikolaus E. Wolter, Sharon L. Cushing, Elena Pope, Jennifer K. Wolter, Evan J. Propst View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Propranolol versus nadolol for treatment of pediatric subglottic hemangioma

xlomafota13 shared this article with you from Inoreader Propranolol versus nadolol for treatment of pediatric subglottic hemangioma Via International Journal of Pediatric Otorhinolaryngology Publication date: Available online 21 March 2021 Source: International Journal of Pediatric Otorhinolaryngology Author(s): Weining Yang, Nikolaus E. Wolter, Sharon L. Cushing, Elena Pope, Jennifer K. Wolter, Evan J. Propst View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.