Medicine by Alexandros G. Sfakianakis: 03/23/20

MRI Assessment of Swallow Muscle Activation with the Swallow Exercise Aid and with Conventional Exercises in Healthy Volunteers: An Explorative Biomechanical Study.

Related ArticlesMRI Assessment of Swallow Muscle Activation with the Swallow Exercise Aid and with Conventional Exercises in Healthy Volunteers: An Explorative Biomechanical Study. Dysphagia. 2020 Mar 21;: Authors: Karsten RT, Ter Beek LC, Jasperse B, van Alphen MJA, Peeters JM, van der Molen L, Hilgers FJM, Stuiver MM, Smeele LE Abstract Swallowing muscle strength exercises are effective in restoring swallowing function. In order to perform the exercises...

Dysphagia - Rehabilitation

Mon Mar 23, 2020 13:50

Predictors and associating factors of nasogastric tube removal: Clinical and brain imaging data analysis in post-stroke dysphagia.

Related ArticlesPredictors and associating factors of nasogastric tube removal: Clinical and brain imaging data analysis in post-stroke dysphagia. J Formos Med Assoc. 2020 Mar 18;: Authors: Hsueh HW, Chen YC, Chang CF, Wang TG, Chiu MJ Abstract BACKGROUND/PURPOSE: Post-stroke dysphagia is a frequent complication. Although most patients with dysphagia recover after the acute phase, some patients require long-term enteral feeding, either through a nasogastric...

Dysphagia - Rehabilitation

Mon Mar 23, 2020 13:50

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Pathology International

S100A12 promotes inflammation and apoptosis in ischemia/reperfusion injury via ERK signaling in vitro study using PC12 cells

S100A12 is a member of S100 calcium‐binding proteins with effect to promote inflammation in brain damage and stroke. However, the role of S100A12 in ischemia/reperfusion (I/R) remains to be clarified. This study aimed to explore the effect of S100A12 on I/R and discover the possible mechanism. Oxygen‐glucose deprivation and reperfusion (OGD/R) was used to induce I/R injury model in vitro. Knockdown or overexpression of S100A12 was utilized to explore the role of S100A12 in I/R‐induced inflammation...

Pathology International

Mon Mar 23, 2020 13:43

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Music as a scaffold for listening to speech: Better neural phase-locking to song than speech

Publication date: Available online 23 March 2020Source: NeuroImageAuthor(s): Christina M. Vanden Bosch der Nederlanden, Marc Joanisse, Jessica A. Grahn

NeuroImage

Mon Mar 23, 2020 13:55

Facing up to why the wandering mind: Patterns of off-task laboratory thought are associated with stronger neural recruitment of right fusiform cortex while processing facial stimuli

Publication date: Available online 22 March 2020Source: NeuroImageAuthor(s): Nerissa Siu Ping Ho, Giulia Poerio, Delali Konu, Adam Turnbull, Mladen Sormaz, Robert Leech, Boris Bernhardt, Elizabeth Jefferies, Jonathan Smallwood

NeuroImage

Mon Mar 23, 2020 13:55

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Nature Communications - current - nature.com science feeds

CHD4 slides nucleosomes by decoupling entry- and exit-side DNA translocation

Nature Communications, Published online: 23 March 2020; doi:10.1038/s41467-020-15183-2Chromatin remodellers hydrolyse ATP to move nucleosomal DNA against histone octamers. Here, the authors use single-molecule assays to examine the mechanism of action of CHD4 remodeller, and provide evidence that CHD4 slides nucleosomes by decoupling entry- and exit-side DNA translocation.

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Mon Mar 23, 2020 02:00

Infrared spectroscopy data- and physics-driven machine learning for characterizing surface microstructure of complex materials

Nature Communications, Published online: 23 March 2020; doi:10.1038/s41467-020-15340-7Knowing compositional motifs of nanoparticle catalysts in operando conditions is crucial towards understanding their catalytic behavior. Here, the authors develop a physics-driven machine learning approach to predict adsorption sites for a CO molecule over platinum nanoparticles in a multitude of coordination environments.

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Mon Mar 23, 2020 02:00

Ferromagnetic quasi-atomic electrons in two-dimensional electride

Nature Communications, Published online: 23 March 2020; doi:10.1038/s41467-020-15253-5Ferromagnetic quasi-atomic behavior of interstitial anionic electrons (IAEs) in practical electrides is yet to be discovered experimentally. Here, the authors reveal that IAEs in two-dimensional electride [Gd2C]²+⋅2e- behave as magnetic elements with their own magnetic moment.

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Mon Mar 23, 2020 02:00

Developing a highly efficient hydroxytyrosol whole-cell catalyst by de-bottlenecking rate-limiting steps

Nature Communications, Published online: 23 March 2020; doi:10.1038/s41467-020-14918-5Whole-cell catalyst-based hydroxytyrosol production is low. Here, the authors increase the efficiency of its production in E. coli by de-bottlenecking two enzymatic steps catalyzed by monooxygenase and tyramine oxidase using structure-based enzyme redesign or in vivo-directed evolution with the aid of a newly developed biosensor.

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Mon Mar 23, 2020 02:00

An expanded library of orthogonal split inteins enables modular multi-peptide assemblies

Nature Communications, Published online: 23 March 2020; doi:10.1038/s41467-020-15272-2Inteins allow the joining of protein segments through scarless ligation. Here the authors assess 34 inteins to establish a library of 15 mutually orthogonal split inteins for in vivo applications, 10 of which are also active in vitro.

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Mon Mar 23, 2020 02:00

Publisher Correction: Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression

Nature Communications, Published online: 23 March 2020; doi:10.1038/s41467-020-15098-yPublisher Correction: Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression

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Mon Mar 23, 2020 02:00

Fungal kinases and transcription factors regulating brain infection in <i>Cryptococcus neoformans</i>

Nature Communications, Published online: 23 March 2020; doi:10.1038/s41467-020-15329-2Cryptococcus neoformans causes fatal fungal meningoencephalitis. Here, the authors identify fungal kinases and transcription factors involved in blood-brain barrier crossing and brain infection in mice.

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Mon Mar 23, 2020 02:00

Structural insights into catalytic mechanism and product delivery of cyanobacterial acyl-acyl carrier protein reductase

Nature Communications, Published online: 23 March 2020; doi:10.1038/s41467-020-15268-yAcyl-acyl carrier protein reductase (AAR) and aldehyde deformylating oxygenase (ADO) are the two enzymes in a cyanobacterial alkane biosynthesis pathway that is of interest for biofuel production. Here the authors provide insights into the catalytic mechanisms of AAR and the coupling between the two enzymes by determining the crystal structures of AAR alone and three AAR–ADO complexes with various bound ligands.

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Mon Mar 23, 2020 02:00