Two Latest Hot Researches in Medicinal Chemistry....
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
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Κυριακή 5 Απριλίου 2020
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com, Telephone consultation 11855 int 1193,
Two Latest Hot Researches in Medicinal Chemistry....
Related ArticlesTwo Latest Hot Researches in Medicinal Chemistry. Curr Top Med Chem. 2020;20(4):264-265 Authors: Zhou GP, Chou KC PMID: 32238127 [PubMed - as supplied by publisher]
Fri Apr 03, 2020 15:12
Related ArticlesTargeting KDM5 Demethylases: Inhibition and Degradation. Curr Top Med Chem. 2020;20(4):261-263 Authors: Fu X, Yang C, Yu B PMID: 32238126 [PubMed - as supplied by publisher]
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Related ArticlesRepair of Massive Bone Defects of the Proximal Femur Using Iliac Bone Flaps of the Ascending Branch of the Lateral Circumflex Femoral Artery: A Retrospective Report. Ann Plast Surg. 2020 Apr 01;: Authors: Li Z, Yu A, Yu G, Tao S, Qi B Abstract BACKGROUND AND OBJECTIVE: The management of bone defects is still a difficult problem. Local vascularized bone grafts represent an efficient and widely used method. In this retrospective report,...
Sat Apr 04, 2020 15:39
Clinical Outcomes After Hematoma Development: A Study of 627 Tissue Expander Breast Reconstructions.
Related ArticlesClinical Outcomes After Hematoma Development: A Study of 627 Tissue Expander Breast Reconstructions. Ann Plast Surg. 2020 Apr 01;: Authors: Rogoff H, Marquez JE, Ghosh K, Jou C, McAuliffe P, Rathi S, Monroig K, Medrano C, Marmor WA, Ferrier A, Kapadia K, Klein G, Huston TL, Ganz J, Dagum AB, Khan S, Bui D Abstract BACKGROUND: Hematomas after tissue expander immediate breast reconstruction (TE-IBR) pose a significant challenge during the...
Sat Apr 04, 2020 15:39
Related ArticlesPoly-4-Hydroxybutyric Acid Mesh Compares Favorably With Acellular Dermal Matrix in Tissue Expander-Based Breast Reconstruction. Ann Plast Surg. 2020 Apr 01;: Authors: Levy AS, Bernstein JL, Xia JJ, Otterburn DM Abstract BACKGROUND: Acellular dermal matrix (ADM) is commonly used during immediate expander-based breast reconstruction, with potential advantages of greater intraoperative expansion, decreased time to complete expansion, and...
Sat Apr 04, 2020 15:39
Abstract Purpose of Review The review provides an update on the diagnosis, pathogenesis, and treatment of cutaneous lupus erythematosus (CLE). Recent Findings Diagnostic challenges exist in better defining CLE as an independent disease distinct from systemic lupus erythematosus with cutaneous features and further classifying CLE based...
Sat Apr 04, 2020 03:00
Abstract Purpose of Review Idiopathic pulmonary hemosiderosis (IPH) is one of the rarest and least understood causes of pulmonary hemorrhage in children. Illustrated by a complex case presentation, we discuss the clinical manifestations, diagnosis, pathology, proposed etiologies, and treatment of this rare disease. We also compare IPH with anti-glomerular basement membrane antibody syndrome (anti-GBM disease), another rare causes...
Sat Apr 04, 2020 03:00
Videosprechstunden in Zeiten der Corona-Krise. Laryngorhinootologie. 2020 Apr 02;: Authors: Hübner L, Wienke A PMID: 32242329 [PubMed - as supplied by publisher]
Sat Apr 04, 2020 13:31
Related Articles[Paramedian neck mass (rare differential diagnosis)]. Laryngorhinootologie. 2020 Apr 01;: Authors: Jadeed R, Braunschweig T, Westhofen M PMID: 32236914 [PubMed - as supplied by publisher]
Fri Apr 03, 2020 13:20
Related ArticlesAntibiogram of Urinary Enterococcus isolates from a tertiary care hospital. Infect Disord Drug Targets. 2020 Apr 03;: Authors: Bhat NR, Shivashankar SBK, Dhanashree B Abstract PURPOSE: Urinary tract infection (UTI) is one of the serious infections caused by enterococci. VancomycinResistant Enterococci (VRE), is a persevering clinical problem globally. This study aims to detect high-level aminoglycoside and vancomycin resistance in uropathogenic...
Sat Apr 04, 2020 16:16
Related ArticlesColistin Induced Assortment of Antimicrobial Resistance in a Clinical Isolate of Acinetobacter baumannii SD01. Infect Disord Drug Targets. 2019 Apr 26;: Authors: Paul D, Mallick S, Das S, Saha S, Ghosh AK, Mandal SM Abstract Colistin was considered as the most effective antibiotic against Acinetobacter baumannii, a widely-known opportunistic pathogen. In recent years, a number of colistin resistant strains have also been reported. This...
Fri Apr 03, 2020 13:27
Publication date: June 2020Source: World Neurosurgery, Volume 138Author(s): Pravin Salunke, Madhivanan Karthigeyan, Chirag Kamal Ahuja, Chirag Panchal
Sat Apr 04, 2020 13:15
Cervical Laminoplasty for Resection of Hemorrhagic Cavernous Malformation Using a Biportal Technique
Publication date: June 2020Source: World Neurosurgery, Volume 138Author(s): William T. Couldwell, Meic H. Schmidt, Vance Mortimer
Sat Apr 04, 2020 13:15
Publication date: June 2020Source: World Neurosurgery, Volume 138Author(s): Yuki Matsunaga, Yoichi Morofuji, Nobutaka Horie
Sat Apr 04, 2020 13:15
Publication date: June 2020Source: World Neurosurgery, Volume 138Author(s): Glen J. Paton, Brendon K. Billings
Fri Apr 03, 2020 12:53
Publication date: June 2020Source: World Neurosurgery, Volume 138Author(s): Yikui Liu, Jian Li, Yu Duan, Yao Ye, Li Xiao, Renling Mao
Fri Apr 03, 2020 12:53
Related ArticlesSick leave and return to work after surgery for type II SLAP lesions of the shoulder: a secondary analysis of a randomised sham-controlled study. BMJ Open. 2020 Apr 01;10(4):e035259 Authors: Brox JI, Skare Ø, Mowinckel P, Brox JS, Reikerås O, Schrøder CP Abstract OBJECTIVES: To compare days on sick leave and assess predictors of return to work following shoulder surgery. DESIGN: A secondary analysis of a randomised controlled...
Sat Apr 04, 2020 15:08
Related ArticlesAcupuncture for poststroke hemiplegia focusing on cerebral bilateral connections: study protocol for a randomised controlled neuroimaging trial. BMJ Open. 2020 Apr 01;10(4):e034548 Authors: Jiang L, Geng H, Lu M, Du Z, Chen P, Han X, Wang Y, Tang L, Tan Z, Zhang H, Zou Y Abstract INTRODUCTION: Acupuncture is safe and effective for improving the motor function of poststroke hemiplegic patients, but there still exists a certain gap between...
Sat Apr 04, 2020 15:08
Related ArticlesOutcome measures evaluating physical functioning and their measurement properties in adolescent idiopathic scoliosis: a protocol for a systematic review. BMJ Open. 2020 Apr 01;10(4):e034286 Authors: Alamrani S, Rushton A, Gardner A, Falla D, Heneghan NR Abstract INTRODUCTION: Physical functioning (PF) is the ability to carry out the physical activity of daily living. It is an important outcome that provides a meaningful evaluation of...
Sat Apr 04, 2020 15:08
Related ArticlesDevelopment and internal validation of a multimorbidity index that predicts healthcare utilisation using the Canadian Longitudinal Study on Aging. BMJ Open. 2020 Apr 01;10(4):e033974 Authors: Wang Z, Boulanger L, Berger D, Gaudreau P, Marrie RA, Potter B, Wister A, Wolfson C, Lefebvre G, Sylvestre MP, Keezer M Abstract OBJECTIVES: We aimed to develop and internally validate a measure of multimorbidity burden using data from the Canadian...
Sat Apr 04, 2020 15:08
Related ArticlesBirth incidence, deaths and hospitalisations of children and young people with Down syndrome, 1990-2015: birth cohort study. BMJ Open. 2020 Apr 01;10(4):e033770 Authors: Hughes-McCormack LA, McGowan R, Pell JP, Mackay D, Henderson A, O'Leary L, Cooper SA Abstract OBJECTIVE: To investigate current Down syndrome live birth and death rates, and childhood hospitalisations, compared with peers. SETTING: General community. ...
Sat Apr 04, 2020 15:08
Related ArticlesLongitudinal cohort of HIV-negative transgender women of colour in New York City: protocol for the TURNNT ('Trying to Understand Relationships, Networks and Neighbourhoods among Transgender women of colour') study. BMJ Open. 2020 Apr 01;10(4):e032876 Authors: Callander D, Schneider JA, Radix A, Chaix B, Scheinmann R, Love G, Smith J, Regan SD, Kawachi I, St James K, Ransome Y, Herrera C, Reisner SL, Doroshow C, Poteat T, Watson K, Bluebond-Langner R, Toussaint...
Sat Apr 04, 2020 15:08
Related ArticlesEvaluating a group-based Yoga of Stress Resilience programme: a pragmatic before-after interventional study protocol. BMJ Open. 2020 Mar 31;10(3):e035862 Authors: Alvarez E, Sutton A, Barton B, Vaidya S Abstract INTRODUCTION: Rates of mental health illnesses and burnout are increasing internationally. Therapeutic yoga is increasingly used to improve and maintain physical, mental and emotional well-being and general health. This protocol...
Fri Apr 03, 2020 14:06
Related ArticlesMaternal multivitamin intake and orofacial clefts in offspring: Japan Environment and Children's Study (JECS) cohort study. BMJ Open. 2020 Mar 30;10(3):e035817 Authors: Yoshida S, Takeuchi M, Kawakami C, Kawakami K, Ito S, Japan Environment and Children's Study Group Abstract OBJECTIVES: Orofacial clefts are common birth defects with a lack of strong evidence regarding their association with maternal nutrition. We aimed to determine whether...
Fri Apr 03, 2020 14:06
Related Articles'You have got a foreign body in there': renal transplantation, unexpected mild-to-moderate distress and patients' support needs: a qualitative study. BMJ Open. 2020 Mar 31;10(3):e035627 Authors: Jones J, Damery S, Allen K, Nicholas J, Baharani J, Combes G Abstract OBJECTIVE: To explore why transplant patients experience unexpected mild-to-moderate distress and what support they may need. DESIGN: Qualitative study using individual...
Fri Apr 03, 2020 14:06
Related ArticlesAssessing the feasibility of a rapid, high-volume cervical cancer screening programme using HPV self-sampling and digital colposcopy in rural regions of Yunnan, China. BMJ Open. 2020 Mar 30;10(3):e035153 Authors: Goldstein A, Goldstein LS, Lipson R, Bedell S, Wang J, Stamper SA, Brenner G, Goldstein GR, O'Keefe KD, O'Keefe SC, O'Keefe M, O'Keefe T, Goldstein AR, Zhao A Abstract OBJECTIVE: Implementation of a novel, rapid, high-volume,...
Fri Apr 03, 2020 14:06
Related ArticlesVideo-based smartphone app ('VIDEA bewegt') for physical activity support in German adults: a study protocol for a single-armed observational study. BMJ Open. 2020 Mar 31;10(3):e034027 Authors: Fischer T, Stumpf P, Reinhardt G, Schwarz PEH, Timpel P Abstract INTRODUCTION: Insufficient physical activity is one of the most important risk factors for non-communicable diseases. Physical activity should therefore be intensively promoted in...
Fri Apr 03, 2020 14:06
Related ArticlesPreferences for end-of-life care: a study protocol for a cross-sectional survey of Chinese frail elderly home residents in Hong Kong. BMJ Open. 2020 Mar 31;10(3):e033862 Authors: Yan B, Xu X, Chau PP, Takemura N, Cheung DY, Chan FH, Lin CC Abstract INTRODUCTION: Existing literature on attitudes toward end-of-life care (EoLC) covers the general public but has little information on the frail elderly population. The aim of the current study...
Fri Apr 03, 2020 14:06
Related ArticlesInvestigating the effectiveness of care delivery at an acute geriatric community hospital for older adults in the Netherlands: a protocol for a prospective controlled observational study. BMJ Open. 2020 Mar 31;10(3):e033802 Authors: Ribbink ME, Macneil-Vroomen JL, van Seben R, Oudejans I, Buurman BM, AGCH study group Abstract INTRODUCTION: Hospital admission in older adults with multiple chronic conditions is associated with unwanted...
Fri Apr 03, 2020 14:06
Related ArticlesLiver function tests and fibrosis scores in a rural population in Africa: a cross-sectional study to estimate the burden of disease and associated risk factors. BMJ Open. 2020 Mar 31;10(3):e032890 Authors: O'Hara G, Mokaya J, Hau JP, Downs LO, McNaughton AL, Karabarinde A, Asiki G, Seeley J, Matthews PC, Newton R Abstract OBJECTIVES: Liver disease is a major cause of morbidity and mortality in sub-Saharan Africa, but its prevalence, distribution...
Fri Apr 03, 2020 14:06
Related ArticlesAssessing efficacy of CytoSorb haemoadsorber for prevention of organ dysfunction in cardiac surgery patients with infective endocarditis: REMOVE-protocol for randomised controlled trial. BMJ Open. 2020 Mar 30;10(3):e031912 Authors: Diab M, Platzer S, Guenther A, Sponholz C, Scherag A, Lehmann T, Velichkov I, Hagel S, Bauer M, Brunkhorst FM, Doenst T Abstract INTRODUCTION: Infective endocarditis (IE) is associated with high mortality and...
Fri Apr 03, 2020 14:06
Related ArticlesImpact of electronic palliative care coordination systems (EPaCCS) on care at the end of life across multiple care sectors, in one clinical commissioning group area, in England: a realist evaluation protocol. BMJ Open. 2020 Mar 31;10(3):e031153 Authors: Pocock L, French L, Farr M, Morris R, Purdy S Abstract INTRODUCTION: Electronic palliative care coordination systems (EPaCCS) aim to support people approaching the end of life (EOL) to...
Fri Apr 03, 2020 14:06
Related ArticlesDeterminants of modern contraceptive use among married women of reproductive age: a cross-sectional study in rural Zambia. BMJ Open. 2020 Mar 31;10(3):e030980 Authors: Lasong J, Zhang Y, Gebremedhin SA, Opoku S, Abaidoo CS, Mkandawire T, Zhao K, Zhang H Abstract OBJECTIVE: Zambia is among the world's top 10 countries with higher fertility rate (5.5 births/woman); unmet family planning need for births spacing (14%) and limiting births...
Fri Apr 03, 2020 14:06
Related ArticlesCombating antibiotic resistance using guidelines and enhanced stewardship in Kenya: a protocol for an implementation science approach. BMJ Open. 2020 Mar 31;10(3):e030823 Authors: Gitaka J, Kamita M, Mureithi D, Ndegwa D, Masika M, Omuse G, Ngari M, Makokha F, Mwaura P, Mathai R, Muregi F, Mwau M Abstract INTRODUCTION: Antimicrobial resistance (AMR) is a growing problem globally especially in Sub-Saharan Africa including Kenya. Without...
Fri Apr 03, 2020 14:06
Related ArticlesOptimization of serum thyroglobulin measured at different time points for prognostic evaluation in differentiated thyroid carcinoma patients. Medicine (Baltimore). 2020 Apr;99(14):e19652 Authors: Mutsuddy P, Jeon S, Yoo SW, Zhang Y, Chowdhury MSA, Kim J, Song HC, Bom HS, Min JJ, Kwon SY Abstract Although serum thyroglobulin (Tg) is a reliable differentiated thyroid carcinoma (DTC) prognostic marker, its cutoff values can be affected...
Sat Apr 04, 2020 15:11
Related ArticlesReferral Practice for Radioactive Iodine Ablation (RAI) after ATA guidelines 2015: results from a Tertiary Cancer Care Centre. Eur Arch Otorhinolaryngol. 2020 Apr 02;: Authors: Dhar H, Thiagarajan S, Yousuf A, Nayyar SS, Chaukar D Abstract INTRODUCTION: The ATA guidelines for differentiated thyroid cancer (DTC) are one of the most widely referred to. Their 2015 edition proposed a new risk stratification system and modified the indications...
Fri Apr 03, 2020 14:39
Related ArticlesClinical experience of treating Graves' hyperthyroidism complicated with malignancy-The possible role of potassium iodide for avoiding the risk of thionamide-associated neutropenia. Endocr J. 2020 Apr 02;: Authors: Okamura K, Bandai S, Fujikawa M, Sato K, Kitazono T Abstract The treatment of Graves' hyperthyroidism (GD) complicated with malignancy is challenging, as anti-thyroid thionamide drugs (ATDs) and anti-cancer chemotherapy...
Fri Apr 03, 2020 14:39
Related ArticlesWhen thyroid labs do not add up, physicians should ask patients about biotin supplements. BMJ Case Rep. 2020 Mar 31;13(3): Authors: Lundin MS, Alratroot A, Abu Rous F, Aldasouqi S Abstract A 69-year-old woman with a remote history of Graves' disease treated with radioactive iodine ablation, who was maintained on a stable dose of levothyroxine for 15 years, presented with abnormal and fluctuating thyroid function tests which were confusing....
Fri Apr 03, 2020 14:39
Related ArticlesPapillary thyroid microcarcinoma presenting as a metastasis to the brain. Ann R Coll Surg Engl. 2020 Apr 01;:e1-e4 Authors: Shawky M, Proctor I, Kurzawinski T, Abdel-Aziz T Abstract The brain is a particularly rare site of metastasis from papillary microcarcinoma, with only few cases described in the literature. We present a case of 59-year-old man who presented with seizures and dysphasia due to left frontal lobe cystic mass, which...
Fri Apr 03, 2020 14:39
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