Intraneural ganglion cyst of the lumbosacral plexus mimicking L5 radiculopathy: A case report

paythelady.612 shared this article with you from Inoreader Intraneural ganglion cyst of the lumbosacral plexus mimicking L5 radiculopathy: A case report Μέσω pubmed: "world j clin cases"... World J Clin Cases. 2021 Jun 16;9(17):4433-4440. doi: 10.12998/wjcc.v9.i17.4433. ABSTRACT BACKGROUND: Intraneural ganglion cysts are benign gelatinous masses that form within the epineurium of a peripheral nerve. Only few cases of intraneural ganglion cyst arising from the hip joint have been reported. CASE SUMMARY: A previously healthy 65-year-old woman who had been experiencing left buttock pain radiating to the dorsum of the foot for 2 years visited our clinic. Prior to visiting the clinic, she underwent lumbar spine magnetic resonance imaging and received physiotherapy, pain killers, and epidural injections based on a presumptive diagnosis of spinal stenosis for 2 years in other hospitals. Repeat magnetic resonance imaging revealed joint connection of the articular branch of the hip joint and rostral extension of the cyst along the L5 spinal nerve near the L5-S1 neural foramen. The patient was diagnosed with intraneural gangl ion cyst arising from the articular branch of the hip joint based on high-resolution magnetic resonance neurography. Using the arthroscopic approach, a cystic opening within the intra-articular space was detected, and cyst decompression was then performed. The pain in the left leg was significantly relieved during the 6-mo follow-up. CONCLUSION: Although intraneural ganglion cysts arising from the hip joint are rare, they can cause typical radicular pain and mimic common L5 radiculopathy. Typical cyst ascent phenomenon starting from the termination of the articular branch on magnetic resonance imaging is a crucial finding indicative of intraneural ganglion cysts arising from the hip joint. PMID:34141811 | PMC:PMC8173415 | DOI:10.12998/wjcc.v9.i17.4433 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Health-related quality of life after gastric cancer treatment in Brazil: Narrative review and reflections

paythelady.612 shared this article with you from Inoreader Health-related quality of life after gastric cancer treatment in Brazil: Narrative review and reflections Μέσω pubmed: "world j clin cases"... World J Clin Cases. 2021 Jun 16;9(17):4123-4132. doi: 10.12998/wjcc.v9.i17.4123. ABSTRACT In Brazil, gastric cancer is the third most common type of cancer among men and fifth among women, with an estimated 13360 new cases among men and 7870 among women each year during the 2020-2022 period. This study presents reflections and attempts to add knowledge to the theme of quality of life (QoL) in patients with gastric adenocarcinoma and describes some of its characteristics in three regions of Brazil, with an evaluation of the disease's impacts in various dimensions of life, as reported by the patients themselves. We performed a narrative review of the literature and a data analysis of studies on QoL in Brazilian patients treated for gastric adenocarcinoma from three different cities in three geographic regions: Brasília (the midwest), Jaú (the southeast), and Macapá (the north). PMID:34141775 | PMC:PMC8173417 | DOI:10.12998/wjcc.v9.i17.4123 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Effectiveness of patient education focusing on circadian pain rhythms: A case report and review of literature

paythelady.612 shared this article with you from Inoreader Effectiveness of patient education focusing on circadian pain rhythms: A case report and review of literature Μέσω pubmed: "world j clin cases"... World J Clin Cases. 2021 Jun 16;9(17):4441-4452. doi: 10.12998/wjcc.v9.i17.4441. ABSTRACT BACKGROUND: Neuropathic pain management should aim at improving quality of life and daily living activities of patients; therefore, emphasis should be placed on pain management including understanding the pain patterns during daily activity. Therefore, lifestyle guidance should be based on a detailed understanding of pain; however, previous studies commonly evaluated pain intensity at a single point in time. We report a case on patient education intervention based on the relationship between pain circadian rhythms and detailed physical activity during the day. CASE SUMMARY: A man in his 60s, who suffered a brachial plexus injury in a traffic accident, presented with neuropathic pain. Early assessment of the importance of daily living activities to the patient, pain rhythmicity, and physical activity, was performed. The early assessments show ed that the pain intensity was lower on days when more light-intensity physical activity (LIPA) was performed, than on days when less LIPA was performed. Consequently, patient education focused on methods to decrease the pain intensity that tended to worsen in the afternoon, and encouraged behavioral changes by suggesting the patient to take walks," which could be used to maintain LIPA in the afternoon. On reassessment, the afternoon LIPA, which had been the focus of attention, had increased and a change was noted in the circadian rhythm of pain. CONCLUSION: Patient education based on a composite assessment elicited positive results in relation to the pain circadian rhythm and physical activity. PMID:34141812< /a> | PMC:PMC8173436 | DOI:10.12998/wjcc.v9.i17.4441 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Liver injury associated with the use of selective androgen receptor modulators and post-cycle therapy: Two case reports and literature review

paythelady.612 shared this article with you from Inoreader Liver injury associated with the use of selective androgen receptor modulators and post-cycle therapy: Two case reports and literature review Μέσω pubmed: "world j clin cases"... World J Clin Cases. 2021 Jun 6;9(16):4062-4071. doi: 10.12998/wjcc.v9.i16.4062. ABSTRACT BACKGROUND: Muscle growth promoters are being developed for the treatment of disease-induced loss of muscle mass. Ligandrol and ostarine are selective androgen receptor modulators (SARMs) with a non-steroidal structure and a presumably more favorable side effect profile. In recent years, these substances with or without "post-cycle therapy" (PCT) are often misused by amateur athletes aiming to promote muscle growth. At the same time, reports on their toxic effects on organ systems are emerging. CASE SUMMARY: We report two cases of liver injury in young men who used ligandrol and/or ostarine for a few weeks followed by the use of substances for PCT. Acute liver injury occurred in both cases after stopping SARMs while on PCT. The clinical picture was dominated by jaundice and fatigue. The biochemical pattern showed a mixed type of injury with n ormal alkaline phosphatase and high concentrations of bilirubin and serum bile acids. Histological evidence showed predominantly cholestatic injury with canalicular bile plugs, ductopenia, and mild hepatocellular damage without significant fibrosis. The patients recovered from the condition after 3 mo. The off target effects of SARMs were likely idiosyncratic, but our report highlights the yet unrecognized effects of other toxic substances used for PCT, supra-therapeutic doses, and the complete absence of monitoring for adverse effects. CONCLUSION: Among muscle-building amateur athletes, SARMs (ligandrol or ostarine) and/or substances in PCT may cause cholestatic liver injury with prolonged recovery. PMID:3414 1767 | PMC:PMC8180234 | DOI:10.12998/wjcc.v9.i16.4062 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Efficacy of topical vs intravenous tranexamic acid in reducing blood loss and promoting wound healing in bone surgery: A systematic review and meta-analysis

paythelady.612 shared this article with you from Inoreader Efficacy of topical <em>vs</em> intravenous tranexamic acid in reducing blood loss and promoting wound healing in bone surgery: A systematic review and meta-analysis Μέσω pubmed: "world j clin cases"... World J Clin Cases. 2021 Jun 16;9(17):4210-4220. doi: 10.12998/wjcc.v9.i17.4210. ABSTRACT BACKGROUND: Tranexamic acid (TXA) has been used as an anti-fibrinolytic drug for over half a century and has received much attention in recent decades. AIM: To evaluate the efficacy of topical vs intravenous TXA in reducing blood loss and promoting wound healing in bone surgery. METHODS: From the electronic resources, PubMed, Cochrane Library, Embase, ISI, and Scopus were used to perform a literature search over the last 10 years between 2010 and 2020. EndNote™ X8 was used for managing the electronic resource. Searches were performed with mesh terms. The data were retracted blindly by two independent reviewers. Random effects were used to deal with potential heterogeneity and I 2 showed heterogeneity. Chi-square (I 2) tests were used to quantify the extent of heterogeneity (P < 0.0 1 was considered statistically significant). The efficacy of topical TXA in reducing blood loss and promoting wound healing in bone surgery was compared with intravenous TXA and placebo. RESULTS: According to the research design, 1360 potentially important research abstracts and titles were discovered in our electronic searches, and 18 papers remained in agreement with our inclusion criteria. It was found that TXA reduced 277.51 mL of blood loss compared to placebo, and there was no significant difference between topical TXA and IV TXA in reducing blood loss in bone surgery. Our analyses also showed that TXA significantly reduced blood transfusion compared to placebo and there was no significant difference between topical TXA and IV TXA. CONCLUSION: The use of both topical and intravenous TXA are equally effective in reducing blood loss in bone surgery, which might be beneficial for wound healing after surgery. PMID:34141783 | PMC:PMC8173404 | DOI:10.12998/wjcc.v9.i17.4210 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Complex Airway Management in Patients with Tracheal Cartilaginous Sleeves

xlomafota13 shared this article with you from Inoreader Complex Airway Management in Patients with Tracheal Cartilaginous Sleeves Via The Laryngoscope Objectives/Hypothesis A tracheal cartilaginous sleeve (TCS) is a rare anomaly characterized by anterior fusion of tracheal cartilages. TCS is associated with syndromic craniosynostoses including Apert, Crouzon and Pfeiffer syndromes and FGFR2, FGFR3, and TWIST1 variants. This study presents a 30-year review of patients with syndromic craniosynostosis and TCS and describes diagnostic methods, genetic variants, surgical interventions, and long-term outcomes. Study Design Retrospective, single-institution review. Methods This review included patients with syndromic craniosynostosis and TCS treated at Seattle Children's Hospital from 1990 to 2020. Tracheostomy, genetic variants, and additional surgery were primary measures. Fisher's exact test compared need for tracheostomy in patients with proposed high-risk (FGFR2 p.W290 or FGFR2 p.C342) versus low-risk genetic variants. Results Thirty patients with TCS were identified. Average age at diagnosis was 12 months (range 2-weeks to 7.9-years; standard deviation 19.8 months). Syndromes included Pfeiffer (37%), Apert (37%), and Crouzon (26%). Severe obstructive sleep apnea was present in 76% of patients. Tracheostomy was performed in 17 patients (57%); five were successfully decannulated. Additional interventions included adenotonsillectomy (57%), nasal (20%), laryngeal (17%), and craniofacial skeletal surgery (87%). All patients with Pfeiffer syndrome and FGFR2 p.W290C variants and 83% of patients with FGFR2 p.C342 variants required tracheostomy, differing from other variants (P = .02, odds ratio 33, 95% confidence interval 1.56–697.96). One patient (3%) died. Conclusion TCS contributes to multilevel airway obstruction in patients with syndromic craniosynostosis. Genetic testing in patients with FGFR2-related syndromic craniosynostoses may identify those at risk of TCS and facilitate early intervention. A better understanding of this patient population may foster individualized airway management strategies and improve outcomes. Level of Evidence 4 Laryngoscope, 2021 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Speech Performance among Healthy Malay Female Speakers during Dual-Task and Sentence Complexity

xlomafota13 shared this article with you from Inoreader Speech Performance among Healthy Malay Female Speakers during Dual-Task and Sentence Complexity Via Folia Phoniatrica et Logopaedica View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.