Approach to gynecomastia and pseudogynecomastia surgical techniques and its outcome: a systematic review

xlomafota13 shared this article with you from Inoreader Approach to gynecomastia and pseudogynecomastia surgical techniques and its outcome: a systematic review Via Journal of plastic, reconstructive & aesthetic surgery : JPRAS J Plast Reconstr Aesthet Surg. 2022 Feb 20:S1748-6815(22)00079-1. doi: 10.1016/j.bjps.2022.02.008. Online ahead of print. ABSTRACT BACKGROUND: To date, various surgical techniques were developed for gynecomastia and pseudogynecomastia surgery, providing surgeons vast range of options. These variations of techniques, however, may have different efficacy and results depending on the severity of patients' conditions. OBJECTIVES: This review aims to delineate comprehensively the variations of surgical approaches to gynecomastia and pseudogynecomastia in relation to surgical and patients' outcomes. METHODS: Database search (October 28, 2020) from PubMed, Scopus, Science Direct, and Cochrane Library was performed to identify relevant studies using the keywords ("gynecomastia" OR "pseudogynecomastia") AND ("surgery" AND "mastectomy" OR "liposuction") within January 2011-November 2020, published in English. Inclusion criteria were approached according to patients, intervention, comparator, outcomes, and study design (PICOS). Data from the included studies were extracted based on study and subjects' characteristics, type of intervention, and outcome measures. RESULTS: Out of all relevant studies revealed, 53 studies met inclusion criteria with 5345 subjects included. Most subjects, from 44 studies, were classified as Simon's Grade II (68.49%) with idiopathic cause (94.51%). Most cases were approached using the minimally invasive techniques (37.50%) and were highly satisfied. Among intervention groups, complication rates vary from 12.12-22.30%, with the minimally invasive approach having the lowest rate. Hematoma and bruise were the most reported complications. However, the risk of bias was relatively high due to missing data. CONCLUSIONS: Different surgical approaches for gynecomastia treatment have been described and were consistent with good outcomes. To achieve a low rate of complications, the m inimally invasive techniques can be considered, since most patients seem to be satisfied. PMID:35304857 | DOI:10.1016/j.bjps.2022.02.008 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Extensor indicis proprius transfer for the extensor pollicis longus tendon rupture with a two-incision technique

xlomafota13 shared this article with you from Inoreader Extensor indicis proprius transfer for the extensor pollicis longus tendon rupture with a two-incision technique Via Journal of plastic, reconstructive & aesthetic surgery : JPRAS J Plast Reconstr Aesthet Surg. 2022 Mar 2:S1748-6815(22)00129-2. doi: 10.1016/j.bjps.2022.02.047. Online ahead of print. NO ABSTRACT PMID:35304851 | DOI:10.1016/j.bjps.2022.02.047 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

The Relationship Between Pitch Discrimination and Acoustic Voice Measures in a Cohort of Female Speakers

xlomafota13 shared this article with you from Inoreader The Relationship Between Pitch Discrimination and Acoustic Voice Measures in a Cohort of Female Speakers Via Journal of Voice Evidence across a range of musically trained, hearing disordered and voice disordered populations present conflicting results regarding the relationship between pitch discrimination (PD) and voice quality. PD characteristics of female speakers with and without a musical training background and no self-reported voice disorder, and the relationship between PD and voice quality in this particular population, have not been investigated. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

BMI as a risk factor for the development of chronic rhinosinusitis: a prospective population-based study

xlomafota13 shared this article with you from Inoreader BMI as a risk factor for the development of chronic rhinosinusitis: a prospective population-based study Via http://link.springer.com/journal/405,European archives of oto-rhino-laryngology,The European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino Eur Arch Otorhinolaryngol. 2022 Mar 19. doi: 10.1007/s00405-022-07320-y. Online ahead of print. ABSTRACT PURPOSE: Obesity is a growing, global health problem and previous cross-sectional studies have demonstrated an association between obesity and chronic rhinosinusitis (CRS). There is, however, a lack of prospective studies regarding the impact of obesity on developing (new-onset) CRS. METHODS: Questionnaire-based data (n = 5769) relating to new-onset CRS and Body Mass Index (BMI) were collected in 2013 and 2018 from the Telemark population study in Telemark, Norway. Odds ratios for the risk of new-onset CRS in 2018 in relation to BMI in 2013 were calculated, adjusted for smoking habits, asthma, gender and age. RESULTS: When comparing the group with normal weight (18.5 ≤ BMI < 25) with the obese group (BMI ≥ 30), the odds of new-onset CRS was 53% higher [OR 1.53 (1.11, 2.10)] in the obese group. CONCLUSION: CR S is a multifactorial disease with different phenotypes and it is important to consider obesity when assessing patients with CRS in a clinical setting. PMID:35305138 | DOI:10.1007/s00405-022-07320-y View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Molecular diagnosis and targeted treatment of advanced follicular cell-derived thyroid cancer in the precision medicine era

xlomafota13 shared this article with you from Inoreader Molecular diagnosis and targeted treatment of advanced follicular cell-derived thyroid cancer in the precision medicine era Via radioactive iodine Cancer Treat Rev. 2022 Mar 15;106:102380. doi: 10.1016/j.ctrv.2022.102380. Online ahead of print. ABSTRACT Most malignant thyroid tumours are initially treated with surgery or a combination of surgery and radioactive iodine (RAI) therapy. However, in patients with metastatic disease, many tumours become refractory to RAI, and these patients require alternative treatments, such as locoregional therapies and/or systemic treatment with multikinase inhibitors. Improvements in our under standing of the genetic alterations that occur in thyroid cancer have led to the discovery of several targeted therapies with clinical efficacy. These alterations include NTRK (neurotrophic tyrosine receptor kinase) gene fusions, with the tropomyosin receptor kinase inhibitors larotrectinib and entrectinib both approved by the European Medicines Agency and in other markets worldwide. Inhibitors of aberrant proteins resulting from alterations in RET (rearranged during transfection) and BRAF (B-Raf proto-oncogene) have also shown promising efficacy, and so far have received approval by the US Food and Drug Administration. Selpercatinib, a RET kinase inhibitor, was approved for use in Europe in early 2021. With the discovery of multiple actionable targets, it is imperative that effective testing strategies for these genetic alterations are integrated into the diagnostic armamentarium to ensure that patients who could potentially benefit from targeted treatments are identified. In this review, we offer our recommendations on the optimal testing strategies for detecting genetic alterations in thyroid cancer that have the potential to be targeted by molecular therapy. We also discuss the future of treatments for thyroid cancers, including the use of immune checkpoint inhibitors, and new generations of targeted treatments that are being developed to counter acquired tumour resistance. PMID:35305441 | DOI:10.1016/j.ctrv.2022.102380 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

The effects of Cricothyroid Visor Maneuver (CVM) therapy on the voice characteristics of patients with muscular tension dysphonia: A Case Series Study

xlomafota13 shared this article with you from Inoreader The effects of Cricothyroid Visor Maneuver (CVM) therapy on the voice characteristics of patients with muscular tension dysphonia: A Case Series Study Via Journal of Voice The purpose of this study was to assess the effects of a novel manual therapy, the Cricothyroid visor maneuver (CVM) therapy, on acoustic, auditory perceptual and self-assessment ratings in Muscle tension dysphonia (MTD) patients. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Effects of salicylate derivatives on localization of p.H723R allele product of SLC26A4

xlomafota13 shared this article with you from Inoreader Effects of salicylate derivatives on localization of p.H723R allele product of <em>SLC26A4</em> Via Auris Nasus Larynx Publication date: Available online 16 March 2022 Source: Auris Nasus Larynx Author(s): Michio Murakoshi, Yuhi Koike, Shin Koyama, Shinichi Usami, Kazusaku Kamiya, Katsuhisa Ikeda, Yoichi Haga, Kohei Tsumoto, Hiroyuki Nakamura, Noriyasu Hirasawa, Kenji Ishihara, Hiroshi Wada View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.