Sociodemographic Disparities in the Diagnostic Management of Pediatric Thyroid Nodules

alexandrossfakianakis shared this article with you from Inoreader Sociodemographic Disparities in the Diagnostic Management of Pediatric Thyroid Nodules via JAMA Otolaryngology–Head & Neck Surgery Online First This cross-sectional study assesses the association of sociode mographic factors with the odds of receiving a biopsy, timeliness of the procedure, and risk of nodule malignancy. View on Web

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Use of Tumor Bed Frozen Section to Assess Final Tumor Margin in Oral Cavity Carcinoma

alexandrossfakianakis shared this article with you from Inoreader Use of Tumor Bed Frozen Section to Assess Final Tumor Margin in Oral Cavity Carcinoma via JAMA Otolaryngology–Head & Neck Surgery Current Issue This cross-sectional study evaluates the accuracy and imp lications of using intraoperative frozen section histopathology samples to assess tumor bed margins in patients undergoing surgery for oral cavity squamous cell carcinoma. View on Web

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Association of Stapedotomy Volume and Patient Sex With Better Outcome

alexandrossfakianakis shared this article with you from Inoreader Association of Stapedotomy Volume and Patient Sex With Better Outcome via JAMA Otolaryngology–Head & Neck Surgery Current Issue This cross-sectional study evaluates demographic characte ristics, surgical characteristics, and audiometric data associated with closure of the air-bone gap to less than 10 dB or 15 dB. View on Web

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Association of Neoadjuvant Pembrolizumab for OCSCC With Adverse Events After Surgery

alexandrossfakianakis shared this article with you from Inoreader Association of Neoadjuvant Pembrolizumab for OCSCC With Adverse Events After Surgery via JAMA Otolaryngology–Head & Neck Surgery Current Issue This cohort study evaluates the incidence of postoperativ e adverse events in treatment-naive patients receiving neoadjuvant pembrolizumab for advanced oral cavity cancer when compared with matched controls. View on Web

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Plasma Circulating Tumor HPV DNA and HPV-Related Oropharynx Cancer—A Caution—Reply

alexandrossfakianakis shared this article with you from Inoreader Plasma Circulating Tumor HPV DNA and HPV-Related Oropharynx Cancer—A Caution—Reply via JAMA Otolaryngology–Head & Neck Surgery Current Issue In Reply Dr Johnson and colleagues raise a good point, as expressed in our article, that our findings should not be inferred to suggest that circulating tumor human papillomavirus (HPV) DNA (ctHPVDNA) is ready to be used for screening. Our observation that no ctHPVDNA was detected in healthy participants with detectable salivary HPV DNA or E6 serum antibody suggests a low false-positive rate (ie, suggests good specificity). However, as pointed out in the discussion of our research letter, and by Johnson et al, it is possible that the detecti on methods used in our study could be insensitive, and additional research is needed to verify the finding of high specificity in our study. View on Web

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Outcomes in Patients With Head and Neck Squamous Cell Carcinoma Treated With Checkpoint Inhibitors

alexandrossfakianakis shared this article with you from Inoreader Outcomes in Patients With Head and Neck Squamous Cell Carcinoma Treated With Checkpoint Inhibitors via JAMA Otolaryngology–Head & Neck Surgery Current Issue This cohort study assesses survival outcomes and response rates among patients with recurrent or metastatic mucosal head and neck squamous cell carcinoma treated with checkpoint inhibitors with or without chemotherapy. View on Web

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A Novel Molecular Test for Determining HPV Integration Status in HPV-Positive Oropharynx Cancers

alexandrossfakianakis shared this article with you from Inoreader A Novel Molecular Test for Determining HPV Integration Status in HPV-Positive Oropharynx Cancers via JAMA Otolaryngology–Head & Neck Surgery Current Issue This diagnostic study describes the development of an ass ay for human papillomavirus–driven cancers of the oropharynx and the role viral integration could play in the process. View on Web

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