The Rate of Incidental Atypical and Malignant Breast Lesions in Reduction Mammoplasty Specimens

The Rate of Incidental Atypical and Malignant Breast Lesions in Reduction Mammoplasty Specimens:

Abstract

Aims

Reduction mammoplasty (RM) is one of the most common plastic surgeries in the US. We aimed to demonstrate the rate of incidental atypical and malignant breast lesions (AMBL) found in RM specimens and the impact of the number of submitted tissue sections on the rate of ABL.

Methods and Results

We analyzed our database for patients who underwent reduction mammoplasty between 2000 and 2018. Patients with a history of breast cancer were excluded from the study. All pathology reports were analyzed for AMBL (ALH, LCIS, FEA, ADH, DCIS, invasive carcinoma). The grossing protocol was to submit ten sections from each breast between 2000 and 2013, and six sections between 2014 and 2018. One hundred and sixty‐nine of 5208 patients (3.3%) and 216 of 10,340 RM specimens (2.1%) showed at least one AMBL. Nineteen (0.36%) patients had incidental cancer. The median age of patients with AMBL was significantly higher than patients without ABL (59 vs. 45 years old). There was no cancer in patients < 30 years old. The age‐controlled rate of overall AMBL as well as atypia and cancer only did not decrease by submitting fewer sections during the 2014‐2018 period compared to the 2010‐2013 period.

Conclusion

Decreasing the number of tissue sections from ten to six did not lead to a significant decrease in the rate of overall AMBL or cancer. Our data suggest that submitting six tissue sections from each breast for patients >30 years old and two sections from each breast for patients < 30 years old would be sufficient.