Τρίτη 24 Μαρτίου 2020


Position paper of a German interdisciplinary round table on future designs of trials on adjunctive treatment with antiseizure drugs.
Related ArticlesPosition paper of a German interdisciplinary round table on future designs of trials on adjunctive treatment with antiseizure drugs. Seizure. 2020 Mar 11;78:53-56 Authors: Hamer HM, Holtkamp M, Kaiser T, Fey S, Rozinat K, Mayer T, Schulze-Bonhage A Abstract PURPOSE: Current trials on adjunctive treatment with antiseizure drugs often do not reveal results which are relevant for clinical practice. METHOD: Therefore, an interdisciplinary...
pubmed: epilepsy treatment
Mon Mar 23, 2020 13:30
The feast and famine: epilepsy treatment and treatment gaps in early 21st century.
Related ArticlesThe feast and famine: epilepsy treatment and treatment gaps in early 21st century. Neuropharmacology. 2020 Mar 18;:108055 Authors: Löscher W, Klein P PMID: 32199986 [PubMed - as supplied by publisher]
pubmed: epilepsy treatment
Mon Mar 23, 2020 13:30
Improvement of in situ Follicular Activation and Early Development in Cryopreserved Human Ovarian Cortical Tissue by Co-Culturing with Mesenchymal Stem Cells
Follicular loss and tissue degeneration are great challenges in ovarian tissue culture systems. Mesenchymal stem cells (MSC) secrete a cocktail of growth factors and cytokines which supports adjacent cells and tissues. The aim of the current study was to investigate the impact of human bone marrow (hBM)-MSC, as co-culture cells, on human follicular development in ovarian cortical tissue (OCT) culture. For this purpose, warmed OCT fragments were co-cultured with hBM-MSC for 8 days and compared to...
Cells Tissues Organs
Mon Mar 23, 2020 11:50
Pediatric thyroid cancer: Risk factors for central lymph node metastasis in patients with cN0 papillary carcinoma.
Related ArticlesPediatric thyroid cancer: Risk factors for central lymph node metastasis in patients with cN0 papillary carcinoma. Int J Pediatr Otorhinolaryngol. 2020 Mar 12;133:110000 Authors: Ngo DQ, Ngo QX, Van Le Q Abstract INTRODUCTION: Prophylactic central neck node dissection (CND) for pediatric patients with papillary thyroid cancer (PTC) is still controversial. We aimed to identify the incidence and the predictive parameters of the central...
Head and Neck
Mon Mar 23, 2020 13:35
A review of breath analysis techniques in head and neck cancer.
Related ArticlesA review of breath analysis techniques in head and neck cancer. Oral Oncol. 2020 Mar 19;104:104654 Authors: Dharmawardana N, Woods C, Watson DI, Yazbeck R, Ooi EH Abstract Cancers of the head and neck region are a severely disabling group of diseases with no method for early detection. Analysis of exhaled breath volatile organic compounds shows promise as biomarkers for early detection and disease monitoring. This article reviews...
Head and Neck
Mon Mar 23, 2020 13:35
ATP depletion induced cochlear hair cells death through histone deacetylation in vitro.
Related ArticlesATP depletion induced cochlear hair cells death through histone deacetylation in vitro. Neurosci Lett. 2020 Mar 18;:134918 Authors: Fan B, Wang J, Qiu J, Chen F Abstract Previous studies have shown histone modifications being present in cochlear hair cells in animal models of hearing loss. Our past studies have shown that ATP depletion, histone deacetylase (HDAC) upregulation, and histone deacetylation occur in cochlea after noise...
Head and Neck
Mon Mar 23, 2020 13:35
Is nasogastric tube feeding necessary after hypopharyngeal diverticulum surgery?
Related ArticlesIs nasogastric tube feeding necessary after hypopharyngeal diverticulum surgery? Am J Otolaryngol. 2020 Mar 10;:102453 Authors: Zhukhovitskaya A, Weiland DJ, Goshtasbi K, Verma SP Abstract OBJECTIVES: Nasogastric tubes (NGT) are often placed after surgery for cricopharyngeal muscle pathology due to risk of infection and mediastinitis. The aim of this study was to examine if this practice is necessary. METHODS: A retrospective...
Head and Neck
Mon Mar 23, 2020 13:35
Sleep Apnea Treatment Considerations in Patients with Comorbidities.
Related ArticlesSleep Apnea Treatment Considerations in Patients with Comorbidities. Otolaryngol Clin North Am. 2020 Mar 18;: Authors: Dhanda Patil R, Sarber KM Abstract A wide range of sleep, psychiatric, and medical comorbidities can present with obstructive sleep apnea (OSA), complicating treatment because of intolerance or low adherence to traditional modalities of therapy. Providers must have heightened awareness of how these comorbidities can...
Head and Neck
Mon Mar 23, 2020 13:35
Basaloid squamous cell carcinoma of the breast.
Related ArticlesBasaloid squamous cell carcinoma of the breast. Rev Esp Patol. 2020 Apr - Jun;53(2):113-116 Authors: Marco V, Rubio IT, García F, Clavero O Abstract Basaloid squamous cell carcinoma (BSCC) is a subtype of squamous cell carcinoma that characteristically occurs in the head and neck, may be related to HPV infection and is usually considered to be aggressive. We present the first description of BSCC of the breast. The tumor exhibited...
Head and Neck
Mon Mar 23, 2020 13:35
Appendiceal tumours and pseudomyxoma peritonei: Literature review with PSOGI/EURACAN clinical practice guidelines for diagnosis and treatment.
Related ArticlesAppendiceal tumours and pseudomyxoma peritonei: Literature review with PSOGI/EURACAN clinical practice guidelines for diagnosis and treatment. Eur J Surg Oncol. 2020 Feb 28;: Authors: Govaerts K, Lurvink RJ, De Hingh IHJT, Van der Speeten K, Villeneuve L, Kusamura S, Kepenekian V, Deraco M, Glehen O, Moran BJ, PSOGI Abstract Pseudomyxoma Peritonei (PMP) is a rare peritoneal malignancy, most commonly originating from a perforated epithelial...
pubmed: future oncology
Mon Mar 23, 2020 14:01
Follow-up issues in survivors of hematologic malignancies - Current stance and future perspectives.
Related ArticlesFollow-up issues in survivors of hematologic malignancies - Current stance and future perspectives. Blood Rev. 2020 Feb 26;:100674 Authors: Muhsen IN, Bar M, Savani BN, Estey EH, Hashmi SK Abstract Cancer care advances have led to increased numbers of cancer survivors and to improved understanding of late effects of cancers and their therapies and survivorship issues. Long-term follow-up of cancer patients is crucial in preventing...
pubmed: future oncology
Mon Mar 23, 2020 14:01
The heat shock protein family gene Hspa1l in male mice is dispensable for fertility
Background Heat shock protein family A member 1 like (Hspa1l) is a member of the 70kD heat shock protein (Hsp70) family. HSPA1L is an ancient, evolutionarily conserved gene with a highly conserved domain structure. The gene is highly abundant and constitutively expressed in the mice testes. However, the role of Hspa1l in the testes has still not been elucidated. Methods Hspa1l-mutant mice were generated using the CRISPR/Cas9...
PeerJ Computer Science
Mon Mar 23, 2020 02:00
PigLeg: prediction of swine phenotype using machine learning
Industrial pig farming is associated with negative technological pressure on the bodies of pigs. Leg weakness and lameness are the sources of significant economic loss in raising pigs. Therefore, it is important to identify the predictors of limb condition. This work presents assessments of the state of limbs using indicators of growth and meat characteristics of pigs based on machine learning algorithms. We have evaluated and compared the accuracy of prediction for nine ML classification algorithms...
PeerJ Computer Science
Mon Mar 23, 2020 02:00
Mitochondrial genomes of Columbicola feather lice are highly fragmented, indicating repeated evolution of minicircle-type genomes in parasitic lice
Most animals have a conserved mitochondrial genome structure composed of a single chromosome. However, some organisms have their mitochondrial genes separated on several smaller circular or linear chromosomes. Highly fragmented circular chromosomes (“minicircles”) are especially prevalent in parasitic lice (Insecta: Phthiraptera), with 16 species known to have between nine and 20 mitochondrial minicircles per genome. All of these species belong to the same clade (mammalian lice), suggesting a single...
PeerJ Computer Science
Mon Mar 23, 2020 02:00
Performances of the Canadian Agility and Movement Skill Assessment (CAMSA), and validity of timing components in comparison with three commonly used agility tests in Chinese boys: an exploratory study
Background The practical application of the Canadian Agility and Movement Skill Assessment (CAMSA) has been reported in some Western countries. However, a few studies reported the application of the CAMSA in Chinese children. In addition, given that the CAMSA was designing to incorporate both movement skills and agility assessment, the value and validity of the timing component of the CAMSA are worth discussing. Methods ...
PeerJ Computer Science
Mon Mar 23, 2020 02:00
Prevalence and type distribution of human papillomavirus in a Chinese urban population between 2014 and 2018: a retrospective study
Background Human papilloma virus (HPV) infection is one of the most common sexually transmitted infections among women worldwide. The current study’s main objective is to report the prevalence and distribution of HPV types in an urban population in Beijing, China. Methods All the eligible female participants aged ≥18 years were recruited from the Aerospace Center Hospital in Beijing, China between 2014 and 2018. A total...
PeerJ Computer Science
Mon Mar 23, 2020 02:00
Asthma and allergic diseases are a phenotypic marker for CVID patients?
Publication date: Available online 23 March 2020Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Saba Fekrvand, Hassan Abolhassani, Samaneh Delavari, Reza Yazdani, Asghar Aghamohammadi
ScienceDirect Publication: Annals of Allergy, Asthma & Immunology
Mon Mar 23, 2020 11:44
From Pages of Allergy Watch (June 2020)
Publication date: Available online 23 March 2020Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Vivian Hernandez-Trujillo, John J. Oppenheimer, Stanley Fineman
ScienceDirect Publication: Annals of Allergy, Asthma & Immunology
Mon Mar 23, 2020 11:44
The Journey to an RSV Vaccine
Publication date: Available online 23 March 2020Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Asuncion Mejias, Rosa Rodríguez-Fernández, Silvia Oliva, Mark. E. Peeples, Octavio Ramilo
ScienceDirect Publication: Annals of Allergy, Asthma & Immunology
Mon Mar 23, 2020 11:44
Challenges in the treatment of breast cancer brain metastases: evidence, unresolved questions, and a practical algorithm
Abstract Breast cancer is the leading cause of brain metastases in women. Large randomized clinical trials that have evaluated local therapies in patients with brain metastases include patients with brain metastases from a variety of cancer types. The incidence of brain metastases in the breast cancer population continues to grow, which is, aside from the rising breast cancer incidence, mainly attributable to improvements in systemic therapies leading to more durable control of...
Clinical and translational oncology
Sat Mar 21, 2020 02:00
Photobiomodulation Decreases Hyperalgesia in Complex Regional Pain Syndrome: An Experimental Mouse Model Subjected to Nicotine
Background and Objectives Complex regional pain syndrome (CRPS) is defined as an extreme and chronic pain condition, and photobiomodulation has relevance as a complementary treatment for CRPS. The objective of this study was to verify the effects of photobiomodulation (PBMT) therapy protocols at two wavelengths 660 and 830 nm, associated or not to nicotine in complex regional pain syndrome type I (CRPS‐I). Study Design/Materials and Methods Sixty‐four Swiss mice were divided into the...
Lasers in Surgery and Medicine
Mon Mar 23, 2020 10:56
MRI findings in Pott’s spine and correlating clinical progress with radiological findings
Abstract Purpose To document magnetic resonance imaging (MRI) changes in Pott’s spine and to correlate these with clinical findings and outcome. Methods Patients with Pott’s spine having more than one set of MRI were included in the study. Patients were grouped according to timing of their second MRI. The MRI findings included changes in bone, disc,...
Neuroradiology
Mon Mar 23, 2020 02:00
Large bowel obstruction from a full‐thickness resection device clip: rare complication of a novel technique
ANZ Journal of Surgery
Mon Mar 23, 2020 10:40
Downregulation of lncRNA TUG1 attenuates inflammation and apoptosis of renal tubular epithelial cell induced by ischemia-reperfusion by sponging miR-449b-5p via targeting HMGB1 and MMP2
Abstract We aimed to evaluate the functions of long non-coding RNA taurine upregulated gene 1 (lncRNA TUG1) in renal ischemia-reperfusion (I/R) injury and identify the potential mechanisms. Pathological changes of renal tissues were examined using H&E staining after mimic renal I/R injury in vivo. The contents of serum renal functional parameters and inflammatory factors were measured. The expression of TUG1 and miR-449b-5p in renal...
Latest Results for Inflammation
Mon Mar 23, 2020 02:00
Intratympanic Corticosteroid Administration as a Primary Treatment for Idiopathic Sudden Sensorineural Hearing Loss
Abstract A retrospective review of 34 patients was done who had idiopathic sudden sensorineural hearing loss and were administered intratympanic corticosteroid in the form of dexamethasone (4 mg/ml). The results were interpreted based on pure tone audiometry and Speech discrimination score of the patient before commencing the treatment and after the treatment.
Otolaryngology Indian
Mon Mar 23, 2020 02:00
Contralateral prophylactic mastectomy for unilateral breast cancer in women at average risk‐ systematic review of patient reported outcomes
Abstract Objective The rate of contralateral prophylactic mastectomy (CPM) in women with early, unilateral cancer is relatively high and is increasing around the world.1, 2 Women choose this option for many reasons other than reducing their risk of future cancer, including symmetry, reasons related to breast reconstruction and attempting to manage fear of recurrence. This systematic review evaluated patient‐reported quality of life outcomes following CPM. Methods A literature search...
Psycho-Oncology
Mon Mar 23, 2020 10:02

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