Τετάρτη 1 Απριλίου 2020


Cytomegalovirus and cancer-related mortality in the national health and nutritional examination survey.
Related ArticlesCytomegalovirus and cancer-related mortality in the national health and nutritional examination survey. Cancer Causes Control. 2020 Mar 28;: Authors: Okedele OO, Nelson HH, Oyenuga ML, Thyagarajan B, Prizment A Abstract PURPOSE: Cytomegalovirus (HCMV) is a common viral infection that shapes lifelong immunity. A history of infection with HCMV has been associated with many chronic diseases, including cancer. In addition, prospective...
pubmed: future oncology
Tue Mar 31, 2020 13:15
Small molecules, big impact: 20 years of targeted therapy in oncology.
Related ArticlesSmall molecules, big impact: 20 years of targeted therapy in oncology. Lancet. 2020 Mar 28;395(10229):1078-1088 Authors: Bedard PL, Hyman DM, Davids MS, Siu LL Abstract The identification of molecular targets and the growing knowledge of their cellular functions have led to the development of small molecule inhibitors as a major therapeutic class for cancer treatment. Both multitargeted and highly selective kinase inhibitors are used...
pubmed: future oncology
Tue Mar 31, 2020 13:15
Analysis of determinants for in vitro resistance to the small molecule deubiquitinase inhibitor b-AP15.
Related ArticlesAnalysis of determinants for in vitro resistance to the small molecule deubiquitinase inhibitor b-AP15. PLoS One. 2019;14(10):e0223807 Authors: Mofers A, Perego P, Selvaraju K, Gatti L, Gullbo J, Linder S, D'Arcy P Abstract BACKGROUND: b-AP15/VLX1570 are small molecule inhibitors of the ubiquitin specific peptidase 14 (USP14) and ubiquitin carboxyl-terminal hydrolase 5 (UCHL5) deubiquitinases (DUBs) of the 19S proteasome. b-AP15/VLX1570...
pubmed: future oncology
Tue Mar 31, 2020 13:15
Reproducing the molecular subclassification of peripheral T-cell lymphoma-NOS by immunohistochemistry.
Related ArticlesReproducing the molecular subclassification of peripheral T-cell lymphoma-NOS by immunohistochemistry. Blood. 2019 12 12;134(24):2159-2170 Authors: Amador C, Greiner TC, Heavican TB, Smith LM, Galvis KT, Lone W, Bouska A, D'Amore F, Pedersen MB, Pileri S, Agostinelli C, Feldman AL, Rosenwald A, Ott G, Mottok A, Savage KJ, de Leval L, Gaulard P, Lim ST, Ong CK, Ondrejka SL, Song J, Campo E, Jaffe ES, Staudt LM, Rimsza LM, Vose J, Weisenburger DD, Chan...
pubmed: future oncology
Tue Mar 31, 2020 13:15
IL-7R is essential for leukemia-initiating cell activity of T-cell acute lymphoblastic leukemia.
Related ArticlesIL-7R is essential for leukemia-initiating cell activity of T-cell acute lymphoblastic leukemia. Blood. 2019 12 12;134(24):2171-2182 Authors: González-García S, Mosquera M, Fuentes P, Palumbo T, Escudero A, Pérez-Martínez A, Ramírez M, Corcoran AE, Toribio ML Abstract T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy resulting from the dysregulation of signaling pathways that control intrathymic T-cell...
pubmed: future oncology
Tue Mar 31, 2020 13:15
Is the Vision of Radioligand Therapy for Prostate Cancer Becoming a Reality? An Overview of the Phase III VISION Trial and Its Importance for the Future of Theranostics.
Related ArticlesIs the Vision of Radioligand Therapy for Prostate Cancer Becoming a Reality? An Overview of the Phase III VISION Trial and Its Importance for the Future of Theranostics. J Nucl Med. 2019 11;60(11):1504-1506 Authors: Rahbar K, Bodei L, Morris MJ Abstract Prostate-specific membrane antigen (PSMA) is of considerable interest as a target for diagnostics and therapy of prostate cancer patients. PSMA-targeted imaging has demonstrable value...
pubmed: future oncology
Tue Mar 31, 2020 13:15
Growth and Characterization of Irradiated Organoids from Mammary Glands.
Related ArticlesGrowth and Characterization of Irradiated Organoids from Mammary Glands. J Vis Exp. 2019 05 03;(147): Authors: Hacker BC, Gomez JD, Batista CAS, Rafat M Abstract Organoids derived from the digested tissue are multicellular three-dimensional (3D) constructs that better recapitulate in vivo conditions than cell monolayers. Although they cannot completely model in vivo complexity, they retain some functionality of the original organ. In...
pubmed: future oncology
Tue Mar 31, 2020 13:15
Immuno-PET Imaging to Assess Target Engagement: Experience from 89Zr-Anti-HER3 mAb (GSK2849330) in Patients with Solid Tumors.
Related ArticlesImmuno-PET Imaging to Assess Target Engagement: Experience from 89Zr-Anti-HER3 mAb (GSK2849330) in Patients with Solid Tumors. J Nucl Med. 2019 07;60(7):902-909 Authors: Menke-van der Houven van Oordt CW, McGeoch A, Bergstrom M, McSherry I, Smith DA, Cleveland M, Al-Azzam W, Chen L, Verheul H, Hoekstra OS, Vugts DJ, Freedman I, Huisman M, Matheny C, van Dongen G, Zhang S Abstract PET imaging with radiolabeled drugs provides information...
pubmed: future oncology
Tue Mar 31, 2020 13:15
DOTA-MGS5, a New Cholecystokinin-2 Receptor-Targeting Peptide Analog with an Optimized Targeting Profile for Theranostic Use.
Related ArticlesDOTA-MGS5, a New Cholecystokinin-2 Receptor-Targeting Peptide Analog with an Optimized Targeting Profile for Theranostic Use. J Nucl Med. 2019 07;60(7):1010-1016 Authors: Klingler M, Summer D, Rangger C, Haubner R, Foster J, Sosabowski J, Decristoforo C, Virgolini I, von Guggenberg E Abstract Molecular imaging and targeted radiotherapy with radiolabeled cholecystokinin-2 receptor (CCK2R) targeting peptide probes holds high promise to...
pubmed: future oncology
Tue Mar 31, 2020 13:15
Discussions of Alcohol Use in an Online Social Network for Smoking Cessation: Analysis of Topics, Sentiment, and Social Network Centrality.
Related ArticlesDiscussions of Alcohol Use in an Online Social Network for Smoking Cessation: Analysis of Topics, Sentiment, and Social Network Centrality. Alcohol Clin Exp Res. 2019 01;43(1):108-114 Authors: Cohn AM, Amato MS, Zhao K, Wang X, Cha S, Pearson JL, Papandonatos GD, Graham AL Abstract BACKGROUND: Few Internet smoking cessation programs specifically address the impact of alcohol use during a quit attempt, despite its common role in relapse....
pubmed: future oncology
Tue Mar 31, 2020 13:15

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