Ethosuximide induced macroglossia and oropharyngeal edema.

xloma.fota.13 shared this article with you from Inoreader Ethosuximide induced macroglossia and oropharyngeal edema. Via International journal of pediatric otorhinolaryngology,http://goo.gl/4YdRhz Related Articles Ethosuximide induced macroglossia and oropharyngeal edema. Int J Pediatr Otorhinolaryngol. 2020 Nov 15;:110498 Authors: Shang H, Glaun M, Ongkasuwan J Abstract Acute macroglossia and laryngeal edema are rare adverse side effects that can cause life-threatening airway obstruction. We report a case of acute macroglossia that began after initiation of ethosuximide in a 15-year-old female with severe medically refractory epilepsy. Macroglossia worsened over the next two weeks of ethosuximide administration, preventing extubation. Macroglossia and laryngeal edema improved upon ethosuximide wean, and completely resolved after discontinuation. The patient was extubated successfully, with precautionary nasal trumpet placement and dexamethasone administration prior to extubation. In medically complex patients on multiple pharmacologic agents, anti-epileptic drugs should be suspected as a possible cause of acute macroglossia. PMID: 33218689 [PubMed - as supplied by publisher] View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.