Orthopedic surgery in hemophilic patients with musculoskeletal disorders: A systematic review

xlomafota13 shared this article with you from Inoreader Orthopedic surgery in hemophilic patients with musculoskeletal disorders: A systematic review Via Experimental and therapeutic medicine Exp Ther Med. 2021 Sep;22(3):995. doi: 10.3892/etm.2021.10427. Epub 2021 Jul 14. ABSTRACT Hemophilia is a hereditary coagulopathy caused by factor VIII (hemophilia type A) or by coagulation factor IX (hemophilia type B) dysfunction, characterized by an increased bleeding predisposition, which is either spontaneous or secondary to minimal trauma. Currently, hemophilia may also be considered an 'orthopedic' condition, due to the fact that it affects the musculoskeletal system of most hemophilic patients. In recent years, constant prophylaxis using coagulation factors has led to a significant improvement in the hemophilic patient's quality of life, by reducing both life-threatening hemorrhagic phenomena, as well as the occurrence of chronic complications. Nevertheless, progressive joint bleeding remains unavoidable in this category of patients, and the onset of chronic arthropathy with secondary motor deficiency remains the main complicat ion with an invalidating character. In such cases, orthopedic management is imperative; osteoarticular complications being managed most often with the help of conservative or surgical techniques. The purpose of this review is to provide an overview of modern orthopedic practices which are useful in the management of hemophilic patients suffering from osteoarticular disorders. PMID:34345277 | PMC:PMC8311230 | DOI:10.3892/etm.2021.10427 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.