Comparison between planar and single-photon computed tomography images for radiation intensity quantification in iodine-131 scintigraphy

xlomafota13 shared this article with you from Inoreader Comparison between planar and single-photon computed tomography images for radiation intensity quantification in iodine-131 scintigraphy Via radioactive iodine Sci Rep. 2021 Nov 8;11(1):21858. doi: 10.1038/s41598-021-01432-x. ABSTRACT This study aimed to evaluate the feasibility of quantifying iodine-131 (131I) accumulation in scintigraphy images and compare planar and single-photon emission computed tomography (SPECT) images to estimate 131I radioactivity in patients receiving radioactive iodine therapy for thyroid cancer. We evaluated 72 sets of planar and SPECT images acquired between February 2017 and December 20 18. Simultaneously, we placed a reference 131I capsule next to the patient during image acquisition. We evaluated the correlation between the intensity of the capsule in the images and the capsule dose and estimated the radiation dose at the thyroid bed. The mean capsule dose was 2.14 MBq (range, 0.63-4.31 MBq). The correlation coefficients (p-value) between capsule dose and maximum and mean intensities in both planar and SPECT images were 0.93 (p < 0.01), 0.96 (p < 0.01), 0.60 (p < 0.01), and 0.47 (p < 0.01), respectively. The mean intensities of planar images show the highest correlation coefficients. Based on a regression equation, the average radiation dose in the thyroid bed was 5.9 MBq. In conclusion, planar images reflected the radiation dose more accurately than SPECT images. The regression equation allows to determine the dose in other regions, such as the thyroid bed or sites of distant metastasis. PMID:34750482 | DOI:10.1038/s41598-021-01432-x View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.