Polyfunctional antigen specific CD4± T cell responses in Patients with HIV/AIDS and Histoplasmosis Immune Reconstitution Inflammatory Syndrome

alexandrossfakianakis shared this article with you from Inoreader Polyfunctional antigen specific CD4± T cell responses in Patients with HIV/AIDS and Histoplasmosis Immune Reconstitution Inflammatory Syndrome via Clinical Infectious Diseases Advance Access Abstract In the combination antiretroviral era, there are limited data regarding the pathogenesis of histoplasmosis immune reconstitution inflammatory syndrome (IRIS) in people with HIV. We immunologically characterized ten cases of histoplasmosis, four of whom developed histoplasmosis IRIS. CD4+ T-cells in histoplasmosis IRIS demonstrated a significant polyfunctional cytokine response to histoplasma antigen. View on Web

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