Τετάρτη 8 Ιουνίου 2022

SARS‐CoV‐2and Mutation RT‐qPCR Test Positivity Correlation with ABO and Rh Blood Types

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ABSTRACT

Introduction

Studies show that there may be a relationship between ABO blood type and SARS-CoV-2transmission. It was aimed to determine by investigating the blood type of patients whose one-step reverse transcription and real-time polymerase chain reaction (RT-qPCR) test was positive for Sars-CoV-2.

Materials and Methods

ABO and Rh blood type of individuals whose RT-qPCR test was positive for SARS-CoV-2were examined and an evaluation was made to identify whether there was a relationship between them or not.

Results

The blood type data of 44.928 SARS-CoV-2positive RT-qPCR test results has been obtained. 17.656 (39.29%) were delta, 8048 (17.91%) were alpha, 800 (1.78%) were beta and 3000 (6.67%) were omicrons while 15.424 (34.33%) SARS-CoV-2positive mutation was found to be negative.

Discussion

Our study suggests that O and Rh (-) blood types may provide protection against delta, AB and Rh (+) blood types may hinder omicron infection while A and Rh (+) blood types may be more vulnerable to alpha and delta while B and Rh (+) are more sensitive to beta mutation.

Conclusion

Molecular mechanism underlying the relationship between blood types and SARS-CoV-2infection needs further molecular studies and multi-centered studies.

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