Σάββατο 22 Οκτωβρίου 2022

Therapeutic effects of Rosa Canina, Urtica Dioica and Tanacetum Vulgare Herbal Combination in Treatment of Tinnitus Symptoms; A Double‐blind Randomized Clinical Trial

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Abstract

Objective

To evaluate the effect of Neurotec® herbal capsule (100 mg twice a day for three months) on the tinnitus symptoms in comparison with the placebo.

Design

A double-blind randomized clinical trial

Setting

Otolaryngology clinic of Baqiyatallah Hospital

Participants

Patients suffering from subjective tinnitus

Main outcome measures

Pure tone audiometry (PTA) was measured at 0.5, 1, 2, 4 and 6 KHz frequencies before and after the third month of intervention. In addition, Tinnitus Handicap Inventory (THI) questionnaire as well as visual analogue scale (VAS) for tinnitus loudness, daily annoyance, daily life or sleep disturbance, daily perception and mood alteration were evaluated.

Results

Finally, 103 (69 males and 34 females) patients with a mean age of 51.33±13.91 years were analyzed. In contrast with control group, patients in intervention group showed a remarkable decrease in THI score after three months of treatment (p<0.05). Although both groups had improvements in VAS scores, mood disturbance, daily tinnitus perception and daily life alteration scores were only improved in the intervention group. The mean pure tone air and bone conduction were not significantly different between the control and the intervention group at baseline and three months after the intervention at 0.5,1,2 and 4 kHz (P>0.05).

Conclusion

A three-month treatment with Neurotec Capsules in addition to patient education is of benefit for managing symptoms in patients with chronic tinnitus.

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