Antibiotics, Vol. 9, Pages 26: Trends in Primary Antibiotic Resistance in H. pylori Strains Isolated in Italy between 2009 and 2019 Antibiotics doi: 10.3390/antibiotics9010026 Authors: Saracino Fiorini Zullo Pavoni Saccomanno Vaira Background and aims: the increasing prevalence of strains resistant to antimicrobial agents is a critical issue for the management of Helicobacter pylori infection. This study aimed to evaluate, in Italian naïve patients, H. pylori...
Mon Jan 13, 2020 02:00
Antibiotics, Vol. 9, Pages 25: Conjugation of Penicillin-G with Silver(I) Ions Expands Its Antimicrobial Activity against Gram Negative Bacteria Antibiotics doi: 10.3390/antibiotics9010025 Authors: Ioannis Ketikidis Christina N. Banti Nikolaos Kourkoumelis Constantinos G. Tsiafoulis Christina Papachristodoulou Angelos G. Kalampounias Sotiris K. Hadjikakou Conjugation of penicillin G (PenH) with silver(I) ions forms a new CoMeD (conjugate of metal with a drug) with formula...
Mon Jan 13, 2020 02:00
Antibiotics, Vol. 9, Pages 24: Development and Challenges of Antimicrobial Peptides for Therapeutic Applications Antibiotics doi: 10.3390/antibiotics9010024 Authors: Charles H. Chen Timothy K. Lu More than 3000 antimicrobial peptides (AMPs) have been discovered, seven of which have been approved by the U.S. Food and Drug Administration (FDA). Now commercialized, these seven peptides have mostly been utilized for topical medications, though some have been injected into the body to...
Mon Jan 13, 2020 02:00
Antibiotics, Vol. 9, Pages 23: Designed Antimicrobial Peptides for Topical Treatment of Antibiotic Resistant Acne Vulgaris Antibiotics doi: 10.3390/antibiotics9010023 Authors: Kathryn W. Woodburn Jesse Jaynes L. Edward Clemens Acne vulgaris, caused by the Gram-positive bacterium Cutibacterium acnes, is a prevalent dermatologic condition with substantial cutaneous and psychological morbidity. Mild acne is treated with topical antibiotics with more severe inflammatory forms requiring...
Mon Jan 13, 2020 02:00
Antioxidants, Vol. 9, Pages 72: Oxidative Stress and Cancer: Chemopreventive and Therapeutic Role of Triphala Antioxidants doi: 10.3390/antiox9010072 Authors: Sahdeo Prasad Sanjay K. Srivastava Oxidative stress, caused by the overproduction of free radicals, leads to the development of many chronic diseases including cancer. Free radicals are known to damage cellular biomolecules like lipids, proteins, and DNA that results in activation of multiple signaling pathways, growth factors,...
Mon Jan 13, 2020 02:00
Antioxidants, Vol. 9, Pages 71: Neuroprotective and Neuromodulatory Effects Induced by Cannabidiol and Cannabigerol in Rat Hypo-E22 cells and Isolated Hypothalamus Antioxidants doi: 10.3390/antiox9010071 Authors: Viviana di Giacomo Annalisa Chiavaroli Giustino Orlando Amelia Cataldi Monica Rapino Valentina Di Valerio Sheila Leone Luigi Brunetti Luigi Menghini Lucia Recinella Claudio Ferrante Background: Cannabidiol (CBD) and cannabigerol (CBG) are non-psychotropic...
Mon Jan 13, 2020 02:00
Antioxidants, Vol. 9, Pages 70: Phytochemical Constituents, Antioxidant, Cytotoxic, and Antimicrobial Activities of the Ethanolic Extract of Mexican Brown Propolis Antioxidants doi: 10.3390/antiox9010070 Authors: J. Fausto Rivero-Cruz Jessica Granados-Pineda José Pedraza-Chaverri Jazmin Marlen Pérez-Rojas Ajit Kumar-Passari Gloria Diaz-Ruiz Blanca Estela Rivero-Cruz Propolis is a complex mixture of natural sticky and resinous components produced by honeybees from living...
Mon Jan 13, 2020 02:00
Atmosphere, Vol. 11, Pages 96: UV Index Forecasting under the Influence of Desert Dust: Evaluation against Surface and Satellite-Retrieved Data Atmosphere doi: 10.3390/atmos11010096 Authors: Roshan Koc Abdallah Martin-Pomares Isaifan Fountoukis Human exposure to healthy doses of UV radiation is required for vitamin D synthesis, but exposure to excessive UV irradiance leads to several harmful impacts ranging from premature wrinkles to dangerous skin cancer. However,...
Mon Jan 13, 2020 02:00
Atmosphere, Vol. 11, Pages 95: An Investigation of Parameter Sensitivity of Minimum Complexity Earth Simulator Atmosphere doi: 10.3390/atmos11010095 Authors: Jiewei Chen Huijuan Cui Yangyang Xu Quansheng Ge Climate change, induced by human greenhouse gas emission, has already influenced the environment and society. To quantify the impact of human activity on climate change, scientists have developed numerical climate models to simulate the evolution of the climate system, which...
Mon Jan 13, 2020 02:00
Atmosphere, Vol. 11, Pages 94: PM10 and PM2.5 Qualitative Source Apportionment Using Selective Wind Direction Sampling in a Port-Industrial Area in Civitavecchia, Italy Atmosphere doi: 10.3390/atmos11010094 Authors: Maria Eleonora Soggiu Marco Inglessis Roberta Valentina Gagliardi Gaetano Settimo Giovanni Marsili Ivan Notardonato Pasquale Avino The possibility to discriminate between different emission sources and between natural and anthropogenic contributions is a...
Mon Jan 13, 2020 02:00
Atmosphere, Vol. 11, Pages 93: Changes in Tropical-Cyclone Translation Speed over the Western North Pacific Atmosphere doi: 10.3390/atmos11010093 Authors: Dongna Zhang Han Zhang Jiayu Zheng Xuhua Cheng Di Tian Dake Chen The trend of tropical-cyclone (TC) translation speed is a hot topic recently. Changes in TC translation speed during 1949–2017 over the western North Pacific are analyzed using two best-track datasets here. The TC translation speed decreased during...
Mon Jan 13, 2020 02:00
Atmosphere, Vol. 11, Pages 92: How Can Odors Be Measured? An Overview of Methods and Their Applications Atmosphere doi: 10.3390/atmos11010092 Authors: Carmen Bax Selena Sironi Laura Capelli In recent years, citizens’ attention towards air quality and pollution has increased significantly, and nowadays, odor pollution related to different industrial activities is recognized as a well-known environmental issue. For this reason, odors are subjected to control and regulation...
Mon Jan 13, 2020 02:00
Beverages, Vol. 6, Pages 5: Understanding 21st Century Bordeaux Wines from Wine Reviews Using Naïve Bayes Classifier Beverages doi: 10.3390/beverages6010005 Authors: Zeqing Dong Xiaowan Guo Syamala Rajana Bernard Chen Wine has been popular with the public for centuries; in the market, there are a variety of wines to choose from. Among all, Bordeaux, France, is considered as the most famous wine region in the world. In this paper, we try to understand Bordeaux wines made in the...
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Beverages, Vol. 6, Pages 4: Determination of Anthocyanin and Volatile Profile of Wines from Varieties Yiannoudi and Maratheftiko from the Island of Cyprus Beverages doi: 10.3390/beverages6010004 Authors: Orestis Tsiakkas Carlos Escott Iris Loira Antonio Morata Doris Rauhut José Antonio Suárez-Lepe Anthocyanins and volatile aromas may contribute to the identity of a wine varietal. Various parameters such as terroir (including vineyard altitude), viticultural management,...
Mon Jan 13, 2020 02:00
Bioengineering, Vol. 7, Pages 10: Strontium- and Zinc-Containing Bioactive Glass and Alginates Scaffolds Bioengineering doi: 10.3390/bioengineering7010010 Authors: Asfia Haider Ahmad Waseem Natalia Karpukhina Sahar Mohsin With an increasingly elderly population, there is a proportionate increase in bone injuries requiring hospitalization. Clinicians are increasingly adopting tissue-engineering methods for treatment due to limitations in the use of autogenous and autologous grafts....
Mon Jan 13, 2020 02:00
Biology, Vol. 9, Pages 17: We Do Not Eat Alone: Formation and Maturation of the Oral Microbiota Biology doi: 10.3390/biology9010017 Authors: Luca Fiorillo From the earliest moments of life, contact with the outside world and with other individuals invalidates the sterility of the oral cavity. The oral cavity passes from a sterility condition, that is present only during intrauterine life, to a condition in which a microbiota organizes and evolves itself, accompanying the person throughout...
Mon Jan 13, 2020 02:00
Biomedicines, Vol. 8, Pages 14: Aptamer-Conjugated Tb(III)-Doped Silica Nanoparticles for Luminescent Detection of Leukemia Cells Biomedicines doi: 10.3390/biomedicines8010014 Authors: Yaroslav A. Grechkin Svetlana L. Grechkina Emil A. Zaripov Svetlana V. Fedorenko Asiya R. Mustafina Maxim V. Berezovski DNA aptamers have many benefits for cell imaging, such as high affinity and specificity, easiness of chemical functionalization, and low cost of production. Among known...
Mon Jan 13, 2020 02:00
Biomedicines, Vol. 8, Pages 13: Multifunctional Polymeric Nanoplatforms for Brain Diseases Diagnosis, Therapy and Theranostics Biomedicines doi: 10.3390/biomedicines8010013 Authors: Shahryar Shakeri Milad Ashrafizadeh Ali Zarrabi Rasoul Roghanian Elham Ghasemipour Afshar Abbas Pardakhty Reza Mohammadinejad Anuj Kumar Vijay Kumar Thakur The blood–brain barrier (BBB) acts as a barrier to prevent the central nervous system (CNS) from damage by substances...
Mon Jan 13, 2020 02:00
Biomolecules, Vol. 10, Pages 132: Osmolytes: A Possible Therapeutic Molecule for Ameliorating the Neurodegeneration Caused by Protein Misfolding and Aggregation Biomolecules doi: 10.3390/biom10010132 Authors: Neetu Kushwah Vishal Jain Dhananjay Yadav Most of the neurological disorders in the brain are caused by the abnormal buildup of misfolded or aggregated proteins. Osmolytes are low molecular weight organic molecules usually built up in tissues at a quite high amount during...
Mon Jan 13, 2020 02:00
Biomolecules, Vol. 10, Pages 131: Improving Effects of Hop-Derived Bitter Acids in Beer on Cognitive Functions: A New Strategy for Vagus Nerve Stimulation Biomolecules doi: 10.3390/biom10010131 Authors: Tatsuhiro Ayabe Takafumi Fukuda Yasuhisa Ano Dementia and cognitive decline are global public health problems. Moderate consumption of alcoholic beverages reduces the risk of dementia and cognitive decline. For instance, resveratrol, a polyphenolic compound found in red wine, has...
Mon Jan 13, 2020 02:00
Biomolecules, Vol. 10, Pages 130: Avocado–Soybean Unsaponifiables: A Panoply of Potentialities to Be Exploited Biomolecules doi: 10.3390/biom10010130 Authors: Bahare Salehi Antonio Rescigno Tinuccia Dettori Daniela Calina Anca Oana Docea Laxman Singh Fatma Cebeci Beraat Özçelik Mohammed Bhia Amirreza Dowlati Beirami Javad Sharifi-Rad Farukh Sharopov William C. Cho Natália Martins Avocado and soybean unsaponifiables (ASU) constitute vegetable extracts...
Mon Jan 13, 2020 02:00
Biomolecules, Vol. 10, Pages 129: Preliminary Estimations of Insect Mediated Transfers of Mercury and Physiologically Important Fatty Acids from Water to Land Biomolecules doi: 10.3390/biom10010129 Authors: Sydney Moyo Aquatic insects provide an energy subsidy to riparian food webs. However, most empirical studies have considered the role of subsidies only in terms of magnitude (using biomass measurements) and quality (using physiologically important fatty acids), negating an aspect...
Mon Jan 13, 2020 02:00
Brain Sciences, Vol. 10, Pages 44: Pharmacological Mechanisms Involved in Sensory Gating Disruption Induced by (±)-3,4-Methylene- Dioxymethamphetamine (MDMA): Relevance to Schizophrenia Brain Sciences doi: 10.3390/brainsci10010044 Authors: Jaime Lee Shane Thwaites Andrea Gogos Maarten van den Buuse Sensory gating deficits have been demonstrated in schizophrenia, but the mechanisms involved remain unclear. In the present study, we used disruption of paired-pulse gating of evoked...
Mon Jan 13, 2020 02:00
Cancers, Vol. 12, Pages 200: Deep Sequencing Analysis Reveals Distinctive Non-Coding RNAs When Comparing Tumor Multidrug-Resistant Cells and Extracellular Vesicles with Drug-Sensitive Counterparts Cancers doi: 10.3390/cancers12010200 Authors: Diana Sousa Rune Matthiesen Raquel T. Lima M. Helena Vasconcelos Multidrug resistance (MDR) is one of the main limitations of cancer treatment. The overexpression of drug-efflux pumps, such as P-glycoprotein (P-gp), is a major cause of...
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Cancers, Vol. 12, Pages 199: Deregulating the CYP2C19/Epoxy-Eicosatrienoic Acid-Associated FABP4/FABP5 Signaling Network as a Therapeutic Approach for Metastatic Triple-Negative Breast Cancer Cancers doi: 10.3390/cancers12010199 Authors: Maria Karmella Apaya Pei-Wen Hsiao Yu-Chih Yang Lie-Fen Shyur Recurrence and metastasis are the main causes of triple-negative breast cancer (TNBC) mortality. On the basis of our clinical cohorts and integrative omics analyses, we hypothesized...
Mon Jan 13, 2020 02:00
Cancers, Vol. 12, Pages 197: Potential of Exosomal microRNA-200b as Liquid Biopsy Marker in Pancreatic Ductal Adenocarcinoma Cancers doi: 10.3390/cancers12010197 Authors: Moritz Reese Isabelle Flammang Zixuan Yang Sameer A. Dhayat Pancreatic ductal adenocarcinoma (PDAC) is a highly malignant tumor entity, characterized by rapid disease progression, early metastatic dissemination, and late diagnosis at advanced tumor stages. Recently, we explored the clinical impact of several...
Mon Jan 13, 2020 02:00
Cancers, Vol. 12, Pages 195: Sitravatinib Sensitizes ABCB1- and ABCG2-Overexpressing Multidrug-Resistant Cancer Cells to Chemotherapeutic Drugs Cancers doi: 10.3390/cancers12010195 Authors: Chung-Pu Wu Sung-Han Hsiao Yang-Hui Huang Lang-Cheng Hung Yi-Jou Yu Yu-Tzu Chang Tai-Ho Hung Yu-Shan Wu The development of multidrug resistance (MDR) in cancer patients driven by the overexpression of ATP-binding cassette (ABC) transporter ABCB1 or ABCG2 in cancer cells presents...
Mon Jan 13, 2020 02:00
Cancers, Vol. 12, Pages 196: Serial Xenotransplantation in NSG Mice Promotes a Hybrid Epithelial/Mesenchymal Gene Expression Signature and Stemness in Rhabdomyosarcoma Cells Cancers doi: 10.3390/cancers12010196 Authors: Jan Skoda Jakub Neradil Iva Staniczkova Zambo Alena Nunukova Peter Macsek Karolina Borankova Viera Dobrotkova Pavel Nemec Jaroslav Sterba Renata Veselska Serial xenotransplantation of sorted cancer cells in immunodeficient mice remains the most...
Mon Jan 13, 2020 02:00
Cancers, Vol. 12, Pages 198: Molecular Classification of Gastric Cancer among Alaska Native People Cancers doi: 10.3390/cancers12010198 Authors: Holly A. Martinson Dominic Mallari Christine Richter Tsung-Teh Wu James Tiesinga Steven R. Alberts Matthew J. Olnes Gastric cancer is an aggressive and heterogeneous malignancy that often varies in presentation and disease among racial and ethnic groups. The Alaska Native (AN) people have the highest incidence and mortality...
Mon Jan 13, 2020 02:00
Cancers, Vol. 12, Pages 192: Current Status and Future Perspectives of Immunotherapy for Locally Advanced or Metastatic Urothelial Carcinoma: A Comprehensive Review Cancers doi: 10.3390/cancers12010192 Authors: Tae Jin Kim Kang Su Cho Kyo Chul Koo Advancements in the understanding of tumor immunology in urothelial carcinoma (UC) have led to U.S Food and Drug Administration (FDA) approval of five novel anti-programmed cell death protein-1/ligand 1 (PD-1/L1) checkpoint inhibitors....
Mon Jan 13, 2020 02:00
Cancers, Vol. 12, Pages 194: Systemic Actions of Breast Cancer Facilitate Functional Limitations Cancers doi: 10.3390/cancers12010194 Authors: Ruizhong Wang Harikrishna Nakshatri Breast cancer is a disease of a specific organ, but its effects are felt throughout the body. The systemic effects of breast cancer can lead to functional limitations in patients who suffer from muscle weakness, fatigue, pain, fibromyalgia, or many other dysfunctions, which hasten cancer-associated death....
Mon Jan 13, 2020 02:00
Cancers, Vol. 12, Pages 193: Polyphyllin VI Induces Caspase-1-Mediated Pyroptosis via the Induction of ROS/NF-κB/NLRP3/GSDMD Signal Axis in Non-Small Cell Lung Cancer Cancers doi: 10.3390/cancers12010193 Authors: Jin-Feng Teng Qi-Bing Mei Xiao-Gang Zhou Yong Tang Rui Xiong Wen-Qiao Qiu Rong Pan Betty Yuen-Kwan Law Vincent Kam-Wai Wong Chong-Lin Yu Han-An Long Xiu-Li Xiao Feng Zhang Jian-Ming Wu Da-Lian Qin An-Guo Wu Trillium tschonoskii Maxim...
Mon Jan 13, 2020 02:00
Cells, Vol. 9, Pages 199: Stem Cell-Induced Inflammation in Cholesteatoma is Inhibited by the TLR4 Antagonist LPS-RS Cells doi: 10.3390/cells9010199 Authors: Schürmann Greiner Volland-Thurn Oppel Kaltschmidt Sudhoff Kaltschmidt Cholesteatoma is a severe non-cancerous lesion of the middle ear characterized by massive inflammation, tissue destruction, and an abnormal growth of keratinized squamous epithelium. We recently demonstrated the presence of pathogenic...
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Cells, Vol. 9, Pages 198: Targeting Aberrant RAS/RAF/MEK/ERK Signaling for Cancer Therapy Cells doi: 10.3390/cells9010198 Authors: Degirmenci Wang Hu The RAS/RAF/MEK/ERK (MAPK) signaling cascade is essential for cell inter- and intra-cellular communication, which regulates fundamental cell functions such as growth, survival, and differentiation. The MAPK pathway also integrates signals from complex intracellular networks in performing cellular functions. Despite the initial...
Mon Jan 13, 2020 02:00
Cells, Vol. 9, Pages 196: Glutamine Synthetase 1 Increases Autophagy Lysosomal Degradation of Mutant Huntingtin Aggregates in Neurons, Ameliorating Motility in a Drosophila Model for Huntington’s Disease Cells doi: 10.3390/cells9010196 Authors: Luisa Vernizzi Chiara Paiardi Giusimaria Licata Teresa Vitali Stefania Santarelli Martino Raneli Vera Manelli Manuela Rizzetto Mariarosa Gioria Maria E. Pasini Daniela Grifoni Maria A. Vanoni Cinzia Gellera Franco...
Mon Jan 13, 2020 02:00
Cells, Vol. 9, Pages 197: Mitochondrial Mechanisms of Neuromuscular Junction Degeneration with Aging
Cells, Vol. 9, Pages 197: Mitochondrial Mechanisms of Neuromuscular Junction Degeneration with Aging Cells doi: 10.3390/cells9010197 Authors: Maria-Eleni Anagnostou Russell T. Hepple Skeletal muscle deteriorates with aging, contributing to physical frailty, poor health outcomes, and increased risk of mortality. Denervation is a major driver of changes in aging muscle. This occurs through transient denervation-reinnervation events throughout the aging process that remodel the spatial...
Mon Jan 13, 2020 02:00
Cells, Vol. 9, Pages 195: Hypoxia-Inducible Factor-1α: The Master Regulator of Endothelial Cell Senescence in Vascular Aging Cells doi: 10.3390/cells9010195 Authors: Matilde Alique Elsa Sánchez-López Guillermo Bodega Chiara Giannarelli Julia Carracedo Rafael Ramírez Aging is one of the hottest topics in biomedical research. Advances in research and medicine have helped to preserve human health, leading to an extension of life expectancy. However, the extension of life...
Mon Jan 13, 2020 02:00
Challenges, Vol. 11, Pages 1: Production Challenges in Least Developed Countries Challenges doi: 10.3390/challe11010001 Authors: Matthias Brönner Skander Salah Markus Lienkamp Local production sites in least developed countries offer sustainability for both multinational corporations and local society. However, corporations often hesitate because of uncertain environmental influences on production sites in these countries. To minimize planning uncertainties, we aim to identify...
Mon Jan 13, 2020 02:00
Climate, Vol. 8, Pages 12: The Effects of Historical Housing Policies on Resident Exposure to Intra-Urban Heat: A Study of 108 US Urban Areas Climate doi: 10.3390/cli8010012 Authors: Jeremy S. Hoffman Vivek Shandas Nicholas Pendleton The increasing intensity, duration, and frequency of heat waves due to human-caused climate change puts historically underserved populations in a heightened state of precarity, as studies observe that vulnerable communities—especially those...
Mon Jan 13, 2020 02:00
Diagnostics, Vol. 10, Pages 41: Shear-Wave Elastography Variability Analysis and Relation with Kidney Allograft Dysfunction: A Single-Center Study Diagnostics doi: 10.3390/diagnostics10010041 Authors: Bolboacă Elec Elec Muntean Socaciu Iacob Zaro Andrieș Bădulescu Ignat Iancu Badea Shear-wave elastography (SWE) showed the absence or presence of significant differences among stable kidney allograft function and allograft dysfunction. We evaluated...
Mon Jan 13, 2020 02:00
Diagnostics, Vol. 10, Pages 40: Timely-Automatic Procedure for Estimating the Endocardial Limits of the Left Ventricle Assessed Echocardiographically in Clinical Practice Diagnostics doi: 10.3390/diagnostics10010040 Authors: Darian M. Onchis Codruta Istin Cristina Tudoran Mariana Tudoran Pedro Real In this paper, we propose an analytical rapid method to estimate the endocardial borders of the left ventricular walls on echocardiographic images for prospective clinical integration....
Mon Jan 13, 2020 02:00
Diagnostics, Vol. 10, Pages 39: Biomarkers for Bladder Cancer Diagnosis and Surveillance: A Comprehensive Review Diagnostics doi: 10.3390/diagnostics10010039 Authors: Rui Batista Nuno Vinagre Sara Meireles João Vinagre Hugo Prazeres Ricardo Leão Valdemar Máximo Paula Soares Bladder cancer (BC) ranks as the sixth most prevalent cancer in the world, with a steady rise in its incidence and prevalence, and is accompanied by a high morbidity and mortality. BC is a complex...
Mon Jan 13, 2020 02:00
Diversity, Vol. 12, Pages 29: Neural Network Recognition of Marine Benthos and Corals Diversity doi: 10.3390/d12010029 Authors: Raphael Dubinsky Iluz Netanyahu We present thorough this review the developments in the field, point out their current limitations, and outline its timelines and unique potential. In order to do so we introduce the methods used in each of the advances in the application of deep learning (DL) to coral research that took place between the years: 2016–2018....
Mon Jan 13, 2020 02:00
Diversity, Vol. 12, Pages 28: Thalassic Rotifers from the United States: Descriptions of Two New Species and Notes on the Effect of Salinity and Ecosystem on Biodiversity Diversity doi: 10.3390/d12010028 Authors: Francesca Leasi Willem H. De Smet This study shows the results of a rotifer faunistic survey in thalassic waters from 26 sites located in northeastern U.S. states and one in California. A total of 44 taxa belonging to 21 genera and 14 families were identified, in addition...
Mon Jan 13, 2020 02:00
Foods, Vol. 9, Pages 88: Screening and Spontaneous Mutation of Pickle-Derived Lactobacillus plantarum with Overproduction of Riboflavin, Related Mechanism, and Food Application Foods doi: 10.3390/foods9010088 Authors: Ying-Ying Ge Jia-Rong Zhang Harold Corke Ren-You Gan Riboflavin, also known as vitamin B2, plays an important role in human cell metabolism and participates in various redox reactions and in energy utilization. In this study, 90 riboflavin-producing lactic acid...
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Foods, Vol. 9, Pages 87: Freeze-Drying of Plant-Based Foods Foods doi: 10.3390/foods9010087 Authors: Sagar Bhatta Tatjana Stevanovic Janezic Cristina Ratti Vacuum freeze-drying of biological materials is one of the best methods of water removal, with final products of highest quality. The solid state of water during freeze-drying protects the primary structure and the shape of the products with minimal volume reduction. In addition, the lower temperatures in the process allow maximal...
Mon Jan 13, 2020 02:00
Foods, Vol. 9, Pages 86: Parboiled Paddy Drying with Different Dryers: Thermodynamic and Quality Properties, Mathematical Modeling Using ANNs Assessment Foods doi: 10.3390/foods9010086 Authors: Ebrahim Taghinezhad Antoni Szumny Mohammad Kaveh Vali Rasooli Sharabiani Anil Kumar Naoto Shimizu The effect of hybrid infrared-convective (IRC), microwave (MIC) and infrared-convective-microwave (IRCM) drying methods on thermodynamic (drying kinetics, effective moisture diffusivity...
Mon Jan 13, 2020 02:00
Foods, Vol. 9, Pages 85: Textural Effects on Perceived Satiation and Ad Libitum Intake of Potato Chips in Males and Females Foods doi: 10.3390/foods9010085 Authors: Jimmy Cahayadi Sze Ying Leong Indrawati Oey Mei Peng Food texture plays a critical role in influencing an individual’s perceived satiation and ad libitum intake. It remains unclear, however, whether such textural changes can also affect snack consumption. This study aimed to address this question by testing...
Mon Jan 13, 2020 02:00
Foods, Vol. 9, Pages 84: Powder and Reconstituted Properties of Commercial Infant and Follow-On Formulas Foods doi: 10.3390/foods9010084 Authors: Eoin G. Murphy Nicolas E. Regost Yrjö H. Roos Mark A. Fenelon The physical properties of 15 commercially available infant formulas (IF) and follow-on (FO) formulas were analysed. Powders made with intact milk proteins were classified into two groups; Type I—homogenous mixtures of milk powder particles (n = 6); and Type II—heterogeneous...
Mon Jan 13, 2020 02:00
Geriatrics, Vol. 5, Pages 2: Cannabinoids in the Older Person: A Literature Review Geriatrics doi: 10.3390/geriatrics5010002 Authors: William Beedham Magda Sbai Isabel Allison Roisin Coary David Shipway Introduction: Medical cannabinoids have received significant mainstream media attention in recent times due to an evolving political and clinical landscape. Whilst the efficacy of cannabinoids in the treatment of some childhood epilepsy syndromes is increasingly recognized,...
Mon Jan 13, 2020 02:00
IJERPH, Vol. 17, Pages 514: Study on the Utilization of Inpatient Services for Middle-Aged and Elderly Rural Females in Less Developed Regions of China International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17020514 Authors: Wen Cui Yuan Liu Ouyang Sun Liu Liu Yu Zheng Lu Yuan The aim of this study is to understand the utilization of inpatient services and its contributing factors among middle-aged and elderly...
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IJERPH, Vol. 17, Pages 515: Surgical Smoke—Hazard Perceptions and Protective Measures in German Operating Rooms International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17020515 Authors: Michaelis Hofmann Nienhaus Eickmann (1) Background: Hazardous substances in surgical smoke that is generated during laser or electrosurgery pose a potential health hazard. In Germany, the Technical Rules for Hazardous Substances (TRGS 525) have included recommendations...
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IJERPH, Vol. 17, Pages 512: Response to Buonocore et al. Comments on Wendt Hess et al. “Assessing Agreement in Exposure Classification between Proximity-Based Metrics and Air Monitoring Data in Epidemiology Studies of Unconventional Resource Development.” Int. J. Environ. Res. Public Health 2019, 16, 3055 International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17020512 Authors: Judy Wendt Hess Gerald Bachler Fayaz Momin Krystal Sexton We appreciate...
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IJERPH, Vol. 17, Pages 513: Exploring the Relationship between Green Space in a Neighbourhood and Cardiovascular Health in the Winter City of China: A Study Using a Health Survey for Harbin International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17020513 Authors: Hong Leng Shuyuan Li Shichun Yan Xiuli An A severely cold climate has a significant impact on cardiovascular health, involving temperature, air environment, exercise and diet. Existing studies...
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IJERPH, Vol. 17, Pages 511: Self-Reported General Health, Overall and Work-Related Stress, Loneliness, and Sleeping Problems in 335,625 Swedish Adults from 2000 to 2016 International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17020511 Authors: Victoria Blom Lena V. Kallings Björn Ekblom Peter Wallin Gunnar Andersson Erik Hemmingsson Örjan Ekblom Jonas Söderling Elin Ekblom Bak The prevalence of poor health, in particular stress-related...
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IJERPH, Vol. 17, Pages 510: Reply to Comment on Lecca, L.I.; Portoghese, I.; Mucci, N.; Galletta, M.; Meloni, F.; Pilia, I.; Marcias, G.; Fabbri, D.; Fostinelli, J.; Lucchini, R.G.; Cocco, P.; Campagna, M. Association between Work-Related Stress and QT Prolongation in Male Workers International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17020510 Authors: Luigi Isaia Lecca Igor Portoghese Nicola Mucci Maura Galletta Federico Meloni Ilaria Pilia Gabriele...
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IJERPH, Vol. 17, Pages 509: Sex and Gender Interactions on the Use and Impact of Recreational Cannabis International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17020509 Authors: Lorraine Greaves Natalie Hemsing Cannabis is the second most frequently used substance in the world and regulated or legalized for recreational use in Canada and fourteen US states and territories. As with all substances, a wide range of sex and gender related factors have an influence...
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IJERPH, Vol. 17, Pages 508: Anthropometric and Physical Fitness Profiles of World-Class Male Padel Players International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17020508 Authors: Sánchez-Muñoz Muros Cañas Courel-Ibáñez Sánchez-Alcaraz Zabala The aims of this study were to describe and compare the anthropometric and physical fitness attributes of male padel players according to their competitive level, and to establish a functional anthropometric...
Mon Jan 13, 2020 02:00
IJERPH, Vol. 17, Pages 507: Dynamics of Chinese Diet Divergence from Chinese Food Pagoda and Its Association with Adiposity and Influential Factors: 2004–2011 International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17020507 Authors: Zhou Leepromrath Tian Zhou Nutrition transition in China has a strong impact on dietary quality and health of Chinese consumers. This study developed the diet quality divergence Index (DQD), the divergence between...
Mon Jan 13, 2020 02:00
IJERPH, Vol. 17, Pages 506: Can Children of Different Ages Recognize Dog Communication Signals in Different Situations? International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17020506 Authors: Eretová Chaloupková Hefferová Jozífková The presented study examines the ability of 265 children aged 4–12 years to correctly assign contextual cues and inner state values to a set of audio and audio-visual recordings of dog vocalizations and...
Mon Jan 13, 2020 02:00
IJERPH, Vol. 17, Pages 505: Effects of Teaching Games on Decision Making and Skill Execution: A Systematic Review and Meta-Analysis International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17020505 Authors: Abad Robles Collado-Mateo Fernández-Espínola Castillo Viera Giménez Fuentes-Guerra The question of how games should be taught is still a controversial subject. There has been a growing number of studies on teaching games and coaching sports...
Mon Jan 13, 2020 02:00
IJERPH, Vol. 17, Pages 504: Air Monitoring Stations Far Removed from Drilling Activities do not Represent Residential Exposures to Marcellus Shale Air Pollutants. Response to the Paper by Hess et al. on Proximity-Based Unconventional Natural Gas Exposure Metrics. International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17020504 Authors: Buonocore Casey Croy Spengler McKenzie In their study “Assessing Agreement in Exposure Classification...
Mon Jan 13, 2020 02:00
IJERPH, Vol. 17, Pages 503: Photochemical Generation of Methyl Chloride from Humic Aicd: Impacts of Precursor Concentration, Solution pH, Solution Salinity and Ferric Ion International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17020503 Authors: Hui Liu Yingying Pu Tong Tong Xiaomei Zhu Bing Sun Xiaoxing Zhang Methyl chloride (CH3Cl) is presently understood to arise from biotic and abiotic processes in marine systems. However, the production...
Mon Jan 13, 2020 02:00
IJERPH, Vol. 17, Pages 502: From Sedentary and Physical Inactive Behaviours to an Ultra Cycling Race: A Mixed-Method Case Report International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17020502 Authors: Kenny Guex Sophie Wicht Cyril Besson Francis Degache Boris Gojanovic Gerald Gremion In faculties of health sciences, almost 30% of nursing students exercise less than once a week. This mixed-method case report presents the 38-month evolution...
Mon Jan 13, 2020 02:00
IJERPH, Vol. 17, Pages 501: Factors Shaping the Lived Experience of Resettlement for Former Refugees in Regional Australia International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17020501 Authors: Laura Smith Ha Hoang Tamara Reynish Kim McLeod Chona Hannah Stuart Auckland Shameran Slewa-Younan Jonathan Mond Refugees experience traumatic life events with impacts amplified in regional and rural areas due to barriers accessing services....
Mon Jan 13, 2020 02:00
IJERPH, Vol. 17, Pages 497: Comparative Activation Process of Pb, Cd and Tl Using Chelating Agents from Contaminated Red Soils International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17020497 Authors: Lirong Liu Dinggui Luo Guangchao Yao Xuexia Huang Lezhang Wei Yu Liu Qihang Wu Xiaotao Mai Guowei Liu Tangfu Xiao Adding chelating agents is a critical technique of heavy metal activation for enhancing phytoextraction through the formation...
Mon Jan 13, 2020 02:00
IJERPH, Vol. 17, Pages 499: A Scoping Review of Digital Tools to Reduce Sedentary Behavior or Increase Physical Activity in Knowledge Workers International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17020499 Authors: Ida Damen Hans Brombacher Carine Lallemand Rens Brankaert Aarnout Brombacher Pieter van Wesemael Steven Vos Background: There is increasing interest in the role that technology can play in improving the vitality of knowledge...
Mon Jan 13, 2020 02:00
IJERPH, Vol. 17, Pages 500: Hydrogeochemical Characteristics and Conceptual Model of the Geothermal Waters in the Xianshuihe Fault Zone, Southwestern China International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17020500 Authors: Xiao Li Xun Huang Xin Liao Yunhui Zhang Abundant geothermal waters have been reported in the Yalabamei, Zhonggu, Erdaoqiao, and Yulingong geothermal areas of the Xianshuihe Fault Zone of western Sichuan, southwestern China....
Mon Jan 13, 2020 02:00
IJERPH, Vol. 17, Pages 498: Analysis of Relevant Features from Photoplethysmographic Signals for Atrial Fibrillation Classification International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17020498 Authors: César A. Millán Nathalia A. Girón Diego M. Lopez Atrial Fibrillation (AF) is the most common cardiac arrhythmia found in clinical practice. It affects an estimated 33.5 million people, representing approximately 0.5% of the world’s population....
Mon Jan 13, 2020 02:00
IJERPH, Vol. 17, Pages 496: Time Spent at Work and Its Impact on the Academic Performance of Pharmacy Students International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17020496 Authors: John Okogbaa Rondall E. Allen Daniel F. Sarpong The objective of this study was to determine the impact of time spent at work (workload) on the academic performance of pharmacy students. A cross-sectional 12-item survey was administered to pharmacy students at the end...
Mon Jan 13, 2020 02:00
IJERPH, Vol. 17, Pages 494: Religiosity and Mental Health: A Contribution to Understanding the Heterogeneity of Research Findings International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17020494 Authors: Klara Malinakova Peter Tavel Zdenek Meier Jitse P. van Dijk Sijmen A. Reijneveld Most studies report positive associations between religiosity and spirituality and aspects of mental health, while a small proportion report mixed or fully negative...
Mon Jan 13, 2020 02:00
IJERPH, Vol. 17, Pages 495: Development of a Responsible Policy Index to Improve Statutory and Self-Regulatory Policies that Protect Children’s Diet and Health in the America’s Region International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17020495 Authors: Sofía Rincón-Gallardo Patiño Srijith Rajamohan Kathleen Meaney Eloise Coupey Elena Serrano Valisa E. Hedrick Fabio da Silva Gomes Nicholas Polys Vivica Kraak In 2010, 193 Member...
Mon Jan 13, 2020 02:00
IJERPH, Vol. 17, Pages 493: Environmental Exposures during Puberty: Window of Breast Cancer Risk and Epigenetic Damage International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17020493 Authors: Rama Natarajan Dana Aljaber Dawn Au Christine Thai Angelica Sanchez Alan Nunez Cristal Resto Tanya Chavez Marta M. Jankowska Tarik Benmarhnia Jiue-An Yang Veronica Jones Jerneja Tomsic Jeannine S. McCune Christopher Sistrunk Stacey...
Mon Jan 13, 2020 02:00
IJERPH, Vol. 17, Pages 492: A Computational Biomechanics Human Body Model Coupling Finite Element and Multibody Segments for Assessment of Head/Brain Injuries in Car-To-Pedestrian Collisions International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17020492 Authors: Chao Yu Fang Wang Bingyu Wang Guibing Li Fan Li It has been challenging to efficiently and accurately reproduce pedestrian head/brain injury, which is one of the most important causes...
Mon Jan 13, 2020 02:00
IJERPH, Vol. 17, Pages 491: Effect of Chemotherapy, Laparoscopy, and Cytology on Stage IC Ovarian Clear Cell Carcinoma: A Long-Term, Single-Center Study International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17020491 Authors: Hao-Ting Chang Mei-Ling Chiu Tao-Yuean Wang Tzu-Chien Chen Chih-Long Chang Tsung-Hsien Su Kuo-Gong Wang Kung-Liahng Wang Yuh-Cheng Yang Jen-Ruei Chen Ovarian clear cell carcinoma (OCCC) is the second common...
Mon Jan 13, 2020 02:00
IJERPH, Vol. 17, Pages 490: Characteristics of Standing Postural Control in Women under Additional Load International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17020490 Authors: Bożena Wojciechowska-Maszkowska Dorota Borzucka The aim of this study was to evaluate the effect of additional load on postural-stability control in young women. To evaluate postural control in the 34 women in this study (mean age, 20.8 years), we measured postural sway (center...
Mon Jan 13, 2020 02:00
IJERPH, Vol. 17, Pages 489: Cross Sectional Study on Exposure to BPA and Phthalates and Semen Parameters in Men Attending a Fertility Center International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17020489 Authors: Lidia Caporossi Alessandra Alteri Giovanni Campo Enrico Paci Giovanna Tranfo Silvia Capanna Enrico Papaleo Daniela Pigini Paola Viganò Bruno Papaleo Among the possible risk factors for male reproduction, exposure to phthalates...
Mon Jan 13, 2020 02:00
IJMS, Vol. 21, Pages 512: β-blockers Reverse Agonist-Induced β2-AR Downregulation Regardless of Their Signaling Profile International Journal of Molecular Sciences doi: 10.3390/ijms21020512 Authors: Sonia Maccari Vanessa Vezzi Federica Barbagallo Tonino Stati Barbara Ascione Maria Cristina Grò Liviana Catalano Giuseppe Marano Paola Matarrese Caterina Ambrosio Paola Molinari Altered β-adrenergic receptor (β-AR) density has been reported...
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IJMS, Vol. 21, Pages 511: N-Cadherin mRNA Levels in Peripheral Blood Could Be a Potential Indicator of New Metastases in Breast Cancer: A Pilot Study International Journal of Molecular Sciences doi: 10.3390/ijms21020511 Authors: Takaaki Masuda Hiroki Ueo Yuichiro Kai Miwa Noda Qingjiang Hu Kuniaki Sato Atsushi Fujii Naoki Hayashi Yusuke Tsuruda Hajime Otsu Yosuke Kuroda Hidetoshi Eguchi Shinji Ohno Koshi Mimori Hiroaki Ueo Background: There is...
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IJMS, Vol. 21, Pages 510: Acid Stripping of Surface IgE Antibodies Bound to FcεRI is Unsuitable for the Functional Assays that Require Long-Term Culture of Basophils and Entire Removal of Surface IgE International Journal of Molecular Sciences doi: 10.3390/ijms21020510 Authors: Galeotti Karnam Das Kaveri Bayry Basophils are rare granulocytes and dysregulated functions of these cells are associated with several atopic and non-atopic allergic diseases of skin, respiratory...
Mon Jan 13, 2020 02:00
IJMS, Vol. 21, Pages 507: Human Induced Pluripotent Stem Cells Derived from a Cardiac Somatic Source: Insights for an In-Vitro Cardiomyocyte Platform International Journal of Molecular Sciences doi: 10.3390/ijms21020507 Authors: Lodrini Barile Rocchetti Altomare Reprogramming of adult somatic cells into induced pluripotent stem cells (iPSCs) has revolutionized the complex scientific field of disease modelling and personalized therapy. Cardiac differentiation of human iPSCs...
Mon Jan 13, 2020 02:00
IJMS, Vol. 21, Pages 509: Epigenetic Signaling and RNA Regulation in Cardiovascular Diseases International Journal of Molecular Sciences doi: 10.3390/ijms21020509 Authors: Mongelli Atlante Bachetti Martelli Farsetti Gaetano RNA epigenetics is perhaps the most recent field of interest for translational epigeneticists. RNA modifications create such an extensive network of epigenetically driven combinations whose role in physiology and pathophysiology is still far from...
Mon Jan 13, 2020 02:00
IJMS, Vol. 21, Pages 508: Synthesis of Spin-Labelled Bergamottin: A Potent CYP3A4 Inhibitor with Antiproliferative Activity International Journal of Molecular Sciences doi: 10.3390/ijms21020508 Authors: Balázs Zoltán Zsidó Mária Balog Nikolett Erős Miklós Poór Violetta Mohos Eszter Fliszár-Nyúl Csaba Hetényi Masaki Nagane Kálmán Hideg Tamás Kálai Balázs Bognár Bergamottin (BM, 1), a component of grapefruit juice, acts as an inhibitor of some isoforms of...
Mon Jan 13, 2020 02:00
IJMS, Vol. 21, Pages 504: Macromolecular Interactions of Disordered Proteins International Journal of Molecular Sciences doi: 10.3390/ijms21020504 Authors: Simon Proteins are social beings [...]
Mon Jan 13, 2020 02:00
IJMS, Vol. 21, Pages 505: Role of the Serotonin Receptor 7 in Brain Plasticity: From Development to Disease International Journal of Molecular Sciences doi: 10.3390/ijms21020505 Authors: Crispino Volpicelli Perrone-Capano Our knowledge on the plastic functions of the serotonin (5-HT) receptor subtype 7 (5-HT7R) in the brain physiology and pathology have advanced considerably in recent years. A wealth of data show that 5-HT7R is a key player in the establishment and remodeling...
Mon Jan 13, 2020 02:00
IJMS, Vol. 21, Pages 506: Licochalcone A Inhibits BDNF and TrkB Gene Expression and Hypoxic Growth of Human Tumor Cell Lines International Journal of Molecular Sciences doi: 10.3390/ijms21020506 Authors: Arita Koike Yoshikawa Kondo Hemmi Hypoxic cellular proliferation is a common feature of tumor cells and is associated with tumor progression. Therefore, the inhibition of hypoxic cellular proliferation is expected to regulate malignancy processes. Licochalcone A (LicA)...
Mon Jan 13, 2020 02:00
IJMS, Vol. 21, Pages 503: Early-Life Intervention Using Fecal Microbiota Combined with Probiotics Promotes Gut Microbiota Maturation, Regulates Immune System Development, and Alleviates Weaning Stress in Piglets International Journal of Molecular Sciences doi: 10.3390/ijms21020503 Authors: Quanhang Xiang Xiaoyu Wu Ye Pan Liu Wang Chenbin Cui Yuwei Guo Lingling Zhu Jian Peng Hongkui Wei Previous studies have suggested that immune system development and weaning...
Mon Jan 13, 2020 02:00
IJMS, Vol. 21, Pages 501: Two Distinct C-Type Lysozymes in Goldfish: Molecular Characterization, Antimicrobial Potential, and Transcriptional Regulation in Response to Opposing Effects of Bacteria/Lipopolysaccharide and Dexamethasone/Leptin International Journal of Molecular Sciences doi: 10.3390/ijms21020501 Authors: Ting Chen Yingzhu Rao Jiaxi Li Chunhua Ren Dongsheng Tang Tiehao Lin Jiatai Ji Rong Chen Aifen Yan Lysozymes are key antimicrobial peptides in the...
Mon Jan 13, 2020 02:00
IJMS, Vol. 21, Pages 502: Engineering of Effector Domains for Targeted DNA Methylation with Reduced Off-Target Effects International Journal of Molecular Sciences doi: 10.3390/ijms21020502 Authors: Daniel Hofacker Julian Broche Laura Laistner Sabrina Adam Pavel Bashtrykov Albert Jeltsch Epigenome editing is a promising technology, potentially allowing the stable reprogramming of gene expression profiles without alteration of the DNA sequence. Targeted DNA methylation has...
Mon Jan 13, 2020 02:00
IJMS, Vol. 21, Pages 500: Genome Editing for Mucopolysaccharidoses International Journal of Molecular Sciences doi: 10.3390/ijms21020500 Authors: Edina Poletto Guilherme Baldo Natalia Gomez-Ospina Genome editing holds the promise of one-off and potentially curative therapies for many patients with genetic diseases. This is especially true for patients affected by mucopolysaccharidoses as the disease pathophysiology is amenable to correction using multiple approaches. Ex vivo and...
Mon Jan 13, 2020 02:00
IJMS, Vol. 21, Pages 499: Antimicrobial Chitosan Conjugates: Current Synthetic Strategies and Potential Applications International Journal of Molecular Sciences doi: 10.3390/ijms21020499 Authors: Yukun Qin Pengcheng Li As a natural polysaccharide, chitosan possesses good biocompatibility, biodegradability and biosafety. Its hydroxyl and amino groups make it an ideal carrier material in the construction of polymer-drug conjugates. In recent years, various synthetic strategies have...
Mon Jan 13, 2020 02:00
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