IJMS, Vol. 21, Pages 497: Characterization of the Soybean GmIREG Family Genes and the Function of GmIREG3 in Conferring Tolerance to Aluminum Stress International Journal of Molecular Sciences doi: 10.3390/ijms21020497 Authors: Zhandong Cai Peiqi Xian Rongbin Lin Yanbo Cheng Tengxiang Lian Qibin Ma Hai Nian The IREG (IRON REGULATED/ferroportin) family of genes plays vital roles in regulating the homeostasis of iron and conferring metal stress. This study aims to identify...
IJMS, Vol. 21, Pages 498: Parainfluenza Virus 5 Infection in Neurological Disease and Encephalitis of Cattle International Journal of Molecular Sciences doi: 10.3390/ijms21020498 Authors: Melanie M. Hierweger Simea Werder Torsten Seuberlich The etiology of viral encephalitis in cattle often remains unresolved, posing a potential risk for animal and human health. In metagenomics studies of cattle with bovine non-suppurative encephalitis, parainfluenza virus 5 (PIV5) was identified...
IJMS, Vol. 21, Pages 495: Physicochemical Characterization of Packaging Foils Coated by Chitosan and Polyphenols Colloidal Formulations International Journal of Molecular Sciences doi: 10.3390/ijms21020495 Authors: Lidija Fras Zemljič Olivija Plohl Alenka Vesel Thomas Luxbacher Sanja Potrč In this research, antimicrobial polysaccharide chitosan was used as a surface coating for packaging material. The aim of our research was to establish an additive formulation of chitosan...
IJMS, Vol. 21, Pages 494: Sarcopenic Obesity, Insulin Resistance, and Their Implications in Cardiovascular and Metabolic Consequences International Journal of Molecular Sciences doi: 10.3390/ijms21020494 Authors: So-hyeon Hong Kyung Mook Choi The prevalence of sarcopenic obesity is increasing worldwide, particularly amongst aging populations. Insulin resistance is the core mechanism of sarcopenic obesity and is also associated with variable cardiometabolic diseases such as cardiovascular...
IJMS, Vol. 21, Pages 496: Crosstalk between NLRP12 and JNK during Hepatocellular Carcinoma International Journal of Molecular Sciences doi: 10.3390/ijms21020496 Authors: Shahanshah Khan Hasan Zaki Hepatocellular carcinoma (HCC), a leading cause of cancer-related death, is initiated and promoted by chronic inflammation. Inflammatory mediators are transcriptionally regulated by several inflammatory signaling pathways, including nuclear factor kappa B (NF-κB) and mitogen-activated...
IJMS, Vol. 21, Pages 493: Quercetin in Animal Models of Alzheimer’s Disease: A Systematic Review of Preclinical Studies International Journal of Molecular Sciences doi: 10.3390/ijms21020493 Authors: Xiao-Wen Zhang Jia-Yue Chen Defang Ouyang Jia-Hong Lu Alzheimer’s disease (AD) is the leading cause of dementia worldwide. It involves progressive impairment of cognitive function. A growing number of neuroprotective compounds have been identified with potential anti-AD...
IJMS, Vol. 21, Pages 492: Expression, Purification, and Characterization of Anti-Zika virus Envelope Protein: Polyclonal and Chicken-Derived Single Chain Variable Fragment Antibodies International Journal of Molecular Sciences doi: 10.3390/ijms21020492 Authors: Pharaoh Fellow Mwale Chi-Hsin Lee Liang-Tzung Lin Sy-Jye Leu Yun-Ju Huang Liao-Chun Chiang Yan-Chiao Mao Yi-Yuan Yang Zika virus (ZIKV) is a new and emerging virus that has caused outbreaks worldwide. The...
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JCM, Vol. 9, Pages 219: A Real-World Experience of Clinical, Biochemical and Genetic Assessment of Patients with Homozygous Familial Hypercholesterolemia Journal of Clinical Medicine doi: 10.3390/jcm9010219 Authors: Maria Donata Di Taranto Carola Giacobbe Alessio Buonaiuto Ilenia Calcaterra Daniela Palma Giovanna Maione Gabriella Iannuzzo Matteo Nicola Dario Di Minno Paolo Rubba Giuliana Fortunato Homozygous familial hypercholesterolemia (HoFH), the severest...
JCM, Vol. 9, Pages 218: Presbycusis: An Update on Cochlear Mechanisms and Therapies Journal of Clinical Medicine doi: 10.3390/jcm9010218 Authors: Jing Wang Jean-Luc Puel Age-related hearing impairment (ARHI), also referred to as presbycusis, is the most common sensory impairment seen in the elderly. As our cochlea, the peripheral organ of hearing, ages, we tend to experience a decline in hearing and are at greater risk of cochlear sensory-neural cell degeneration and exacerbated age-related...
JCM, Vol. 9, Pages 217: Pulmonary Arterial Hypertension Induces a Distinct Signature of Circulating Metabolites Journal of Clinical Medicine doi: 10.3390/jcm9010217 Authors: Ruslan Rafikov Dawn K Coletta Lawrence J. Mandarino Olga Rafikova Pulmonary arterial hypertension (PAH) is an incurable, progressive disorder, and the early diagnosis and treatment of PAH are associated with increased survival [...]
JCM, Vol. 9, Pages 216: Do Genomic Factors Play a Role in Diabetic Retinopathy? Journal of Clinical Medicine doi: 10.3390/jcm9010216 Authors: Andrea P. Cabrera Finny Monickaraj Sampathkumar Rangasamy Sam Hobbs Paul McGuire Arup Das Although there is strong clinical evidence that the control of blood glucose, blood pressure, and lipid level can prevent and slow down the progression of diabetic retinopathy (DR) as shown by landmark clinical trials, it has been shown that...
JCM, Vol. 9, Pages 214: Usefulness of the Inferior Articular Process’s Cross-Sectional Area as a Morphological Parameter for Predicting Central Lumbar Spinal Stenosis Journal of Clinical Medicine doi: 10.3390/jcm9010214 Authors: Lee Lim Lim Kim Hypertrophy of facet joints is associated with a high risk of central lumbar spinal stenosis (CLSS). However, no research has reported the effect of inferior articular process hypertrophy in CLSS. We hypothesize that the inferior...
JCM, Vol. 9, Pages 215: Virtual Reality for PEripheral Regional Anesthesia (VR-PERLA Study) Journal of Clinical Medicine doi: 10.3390/jcm9010215 Authors: Camille Alaterre Baptiste Duceau Eileen Sung Tsai Siham Zriouel Francis Bonnet Thomas Lescot Franck Verdonk When used as an add-on to regional anesthesia, virtual reality (VR) has been reported to provide anxiety-reducing benefits and sedation-sparing effects. However, its impact on patient satisfaction is still a...
JCM, Vol. 9, Pages 213: Beneficial Effects of Bariatric Surgery-Induced by Weight Loss on the Proteome of Abdominal Subcutaneous Adipose Tissue Journal of Clinical Medicine doi: 10.3390/jcm9010213 Authors: Bárbara María Varela-Rodríguez Paula Juiz-Valiña Luis Varela Elena Outeiriño-Blanco Susana Belén Bravo María Jesús García-Brao Enrique Mena José Francisco Noguera Javier Valero-Gasalla Fernando Cordido Susana Sangiao-Alvarellos Bariatric surgery (BS) is...
JCM, Vol. 9, Pages 211: Continuous Fentanyl Background Infusion Regimen Optimised by Patient-Controlled Analgesia for Acute Postoperative Pain Management: A Randomised Controlled Trial Journal of Clinical Medicine doi: 10.3390/jcm9010211 Authors: Jihoon Hwang Sang Kee Min Yun Jeong Chae Gang Mee Lim Han Bum Joe Owing to a lack of studies investigating the effect of adjustments in fentanyl background infusion (BI) with patient-controlled analgesia (PCA) on postoperative analgesia,...
JCM, Vol. 9, Pages 212: SERS-Based Liquid Biopsy of Gastrointestinal Tumors Using a Portable Raman Device Operating in a Clinical Environment Journal of Clinical Medicine doi: 10.3390/jcm9010212 Authors: Lucretia Avram Stefania D. Iancu Andrei Stefancu Vlad Moisoiu Alia Colnita Daniel Marconi Valer Donca Elena Buzdugan Rares Craciun Nicolae Leopold Nicolae Crisan Ioan Coman Dana Crisan Early diagnosis based on screening is recognized as one of the...
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Medicina, Vol. 56, Pages 31: Mobbing and Violence at Work as Hidden Stressors and Work Ability Among Emergency Medical Doctors in Serbia Medicina doi: 10.3390/medicina56010031 Authors: Nikolić Višnjić Background and Objectives: People employed in emergency medical services represent a professional group which encounters events beyond ordinary human experience, great work demands, the risk of professional disputes, and stressful situations. The goal of this study is to examine the...
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Metabolites, Vol. 10, Pages 33: Discovering Temporal Patterns in Longitudinal Nontargeted Metabolomics Data via Group and Nuclear Norm Regularized Multivariate Regression Metabolites doi: 10.3390/metabo10010033 Authors: Zhaozhou Lin Qiao Zhang Shengyun Dai Xiaoyan Gao Temporal associations in longitudinal nontargeted metabolomics data are generally ignored by common pattern recognition methods such as partial least squares discriminant analysis (PLS-DA) and orthogonal partial...
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MPs, Vol. 3, Pages 6: Optically Stimulated Luminescence Sensitivity of Quartz for Provenance Analysis Methods and Protocols doi: 10.3390/mps3010006 Authors: André Oliveira Sawakuchi Fernanda Costa Gonçalves Rodrigues Thays Desiree Mineli Vinícius Ribau Mendes Dayane Batista Melo Cristiano Mazur Chiessi Paulo César Fonseca Giannini Finding the source or provenance of quartz grains occurring in a specific location allows us to constrain their transport pathway, which...
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Microorganisms, Vol. 8, Pages 113: Immunobiotic and Paraprobiotic Potential Effect of Lactobacillus casei in a Systemic Toxoplasmosis Murine Model Microorganisms doi: 10.3390/microorganisms8010113 Authors: Angel Gustavo Salas-Lais Atzín Robles-Contreras José Abraham Balderas-López Victor Manuel Bautista-de Lucio One of the main characteristics of probiotics is their ability to stimulate and modulate the immune response regardless of their viability. Lactobacillus casei (Lc)...
Microorganisms, Vol. 8, Pages 112: Dose-Response Recovery of Probiotic Strains in Simulated Gastro-Intestinal Passage Microorganisms doi: 10.3390/microorganisms8010112 Authors: Forssten Ouwehand The probiotic definition stipulates “adequate amounts”. Here, we investigated the metabolic output and recovery rate of probiotic strains using a simulated upper gastro-intestinal passage and colonic fermentation. Two different doses, 7 × 109 colony forming...
Microorganisms, Vol. 8, Pages 111: Bioregional Alterations in Gut Microbiome Contribute to the Plasma Metabolomic Changes in Pigs Fed with Inulin Microorganisms doi: 10.3390/microorganisms8010111 Authors: Weida Wu Li Zhang Bing Xia Shanlong Tang Lei Liu Jingjing Xie Hongfu Zhang Inulin (INU) is a non-digestible carbohydrate, known for its beneficial properties in metabolic disorders. However, whether and how gut microbiota in its regulation contributes to host metabolism...
Microorganisms, Vol. 8, Pages 109: Rapid Detection of Echinocandins Resistance by MALDI-TOF MS in Candida parapsilosis Complex Microorganisms doi: 10.3390/microorganisms8010109 Authors: Ana Emília M. Roberto Danilo E. Xavier Esteban E. Vidal Cláudia Fernanda de L. Vidal Rejane P. Neves Reginaldo G. de Lima-Neto Mass spectrometry by matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) was used to identify and differentiate the pattern of susceptibility...
Microorganisms, Vol. 8, Pages 110: An M29 Aminopeptidase from Listeria Monocytogenes Contributes to In Vitro Bacterial Growth but not to Intracellular Infection Microorganisms doi: 10.3390/microorganisms8010110 Authors: Xian Zhang Chiyu Guan Yi Hang Fengdan Liu Jing Sun Huifei Yu Li Gan Huan Zeng Yiran Zhu Zhongwei Chen Houhui Song Changyong Cheng Aminopeptidases that catalyze the removal of N-terminal residues from polypeptides or proteins are crucial...
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Molecules, Vol. 25, Pages 328: The Generation of the Oxidant Agent of a Mononuclear Nonheme Fe(II) Biomimetic Complex by Oxidative Decarboxylation. A DFT Investigation Molecules doi: 10.3390/molecules25020328 Authors: Angela Parise Maria Costanza Muraca Nino Russo Marirosa Toscano Tiziana Marino The oxidative decarboxylation of the iron(II) α-hydroxy acid (mandelic acid) complex model, biomimetic of Rieske dioxygenase, has been investigated at the density functional...
Molecules, Vol. 25, Pages 327: Editorial to the Special Issue—“Technology for Natural Products Research” Molecules doi: 10.3390/molecules25020327 Authors: Brendan M. Duggan Natural product research continues to be a productive source of unusual chemistry, producing novel compounds for biomedical applications and, increasingly, sustainably providing commercially useful compounds [...]
Molecules, Vol. 25, Pages 326: Tomatidine Represses Invasion and Migration of Human Osteosarcoma U2OS and HOS Cells by Suppression of Presenilin 1 and c-Raf–MEK–ERK Pathway Molecules doi: 10.3390/molecules25020326 Authors: Hsieh Yang Lin Hsieh Yang Chang Lu Osteosarcoma, which is the most prevalent malignant bone tumor, is responsible for the great majority of bone cancer-associated deaths because of its highly metastatic potential. Although tomatidine is suggested...
Molecules, Vol. 25, Pages 325: In Depth Analysis of Kinase Cross Screening Data to Identify CAMKK2 Inhibitory Scaffolds Molecules doi: 10.3390/molecules25020325 Authors: O’Byrne Scott Pilotte Santiago Langendorf Oakhill Eduful Couñago Wells Zuercher Willson Drewry The calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) activates CAMK1, CAMK4, AMPK, and AKT, leading to numerous physiological responses. The deregulation of CAMKK2 is...
Molecules, Vol. 25, Pages 324: Synthesis and Bioactivity of Thiosemicarbazones Containing Adamantane Skeletons Molecules doi: 10.3390/molecules25020324 Authors: Pham Phan Phan Vu Reaction of 4-(1-adamantyl)-3-thiosemicarbazide (1) with numerous substituted acetophenones and benzaldehydes yielded the corresponding thiosemicarbazones containing adamantane skeletons. The synthesized compounds were evaluated for their in vitro activities against some Gram-positive and Gram-negative...
Molecules, Vol. 25, Pages 323: Top-Down Polyelectrolytes for Membrane-Based Post-Combustion CO2 Capture Molecules doi: 10.3390/molecules25020323 Authors: Daria Nikolaeva Patricia Luis Polymer-based CO2 selective membranes offer an energy efficient method to separate CO2 from flue gas. `Top-down’ polyelectrolytes represent a particularly interesting class of polymer materials based on their vast synthetic flexibility, tuneable interaction with gas molecules, ease of processability...
Molecules, Vol. 25, Pages 322: Donor-Acceptor Substituted Benzo-, Naphtho- and Phenanthro-Fused Norbornadienes Molecules doi: 10.3390/molecules25020322 Authors: Mansø Fernandez Wang Moth-Poulsen Nielsen The photochromic norbornadiene/quadricyclane (NBD/QC) couple has found interest as a molecular solar thermal energy (MOST) system for storage of solar energy. To increase the energy difference between the two isomers, we present here the synthesis of a selection of benzo-fused...
Molecules, Vol. 25, Pages 321: In Silico and In Vitro Experimental Studies of New Dibenz[b,e]oxepin-11(6H)one O-(arylcarbamoyl)-oximes Designed as Potential Antimicrobial Agents Molecules doi: 10.3390/molecules25020321 Authors: Vlad Nuta Chirita Caproiu Draghici Dumitrascu Bleotu Avram Udrea Missir Marutescu Limban In a drug-repurposing-driven approach for speeding up the development of novel antimicrobial agents, this paper presents for the...
Molecules, Vol. 25, Pages 320: Management of Fruit Industrial By-Products—A Case Study on Circular Economy Approach Molecules doi: 10.3390/molecules25020320 Authors: Campos Gómez-García Vilas-Boas Madureira Pintado The management of industrial fruit by-products is important not only to decrease the volume of food waste accumulated in the landfills but also to develop strategies through reuse with the purpose to valorise and add economic value. The disposal of food waste...
Molecules, Vol. 25, Pages 319: Heavy Metals as a Factor Increasing the Functional Genetic Potential of Bacterial Community for Polycyclic Aromatic Hydrocarbon Biodegradation Molecules doi: 10.3390/molecules25020319 Authors: Staninska-Pięta Czarny Piotrowska-Cyplik Juzwa Wolko Nowak Cyplik The bioremediation of areas contaminated with hydrocarbon compounds and heavy metals is challenging due to the synergistic toxic effects of these contaminants. On the other...
Molecules, Vol. 25, Pages 317: Comparative Chemical Profiling and Monacolins Quantification in Red Yeast Rice Dietary Supplements by 1H-NMR and UHPLC-DAD-MS Molecules doi: 10.3390/molecules25020317 Authors: Rabab Hachem Gaëtan Assemat Stéphane Balayssac Nathalie Martins-Froment Véronique Gilard Robert Martino Myriam Malet-Martino Red yeast rice dietary supplements (RYR DS) are largely sold in Western countries for their cholesterol-lowering/regulating effect due to...
Molecules, Vol. 25, Pages 318: Bioadhesive Polymeric Films Based on Red Onion Skins Extract for Wound Treatment: An Innovative and Eco-Friendly Formulation Molecules doi: 10.3390/molecules25020318 Authors: Cinzia Pagano Maura Marinozzi Claudio Baiocchi Tommaso Beccari Paola Calarco Maria Rachele Ceccarini Michela Chielli Ciriana Orabona Elena Orecchini Roberta Ortenzi Maurizio Ricci Stefania Scuota Maria Cristina Tiralti Luana Perioli The onion...
Molecules, Vol. 25, Pages 315: Synthesis of Tilmicosin Nanostructured Lipid Carriers for Improved Oral Delivery in Broilers: Physiochemical Characterization and Cellular Permeation Molecules doi: 10.3390/molecules25020315 Authors: Benazir Sahito Qian Zhang Haifeng Yang Lin Peng Xiuge Gao Jam Kashif Zain ul Aabdin Shanxiang Jiang Liping Wang Dawei Guo This study aimed to develop nanostructured lipid carriers (NLCs) for improved oral absorption of tilmicosin...
Molecules, Vol. 25, Pages 316: d-Mannose Treatment neither Affects Uropathogenic Escherichia coli Properties nor Induces Stable FimH Modifications Molecules doi: 10.3390/molecules25020316 Authors: Daniela Scribano Meysam Sarshar Carla Prezioso Marco Lucarelli Antonio Angeloni Carlo Zagaglia Anna Teresa Palamara Cecilia Ambrosi Urinary tract infections (UTIs) are mainly caused by uropathogenic Escherichia coli (UPEC). Acute and recurrent UTIs are commonly treated...
Molecules, Vol. 25, Pages 314: Structure and Thermal Properties of 2,2′-Azobis(1H-Imidazole-4,5-Dicarbonitrile)—A Promising Starting Material for a Novel Group of Energetic Compounds Molecules doi: 10.3390/molecules25020314 Authors: Rafał Lewczuk Maria Książek Katarzyna Gańczyk-Specjalska Katarzyna Cieślak A high-nitrogen compound, 2,2′-azobis(1H-imidazole-4,5-dicarbonitrile) (TCAD), was synthesized from commercially available 2-amino-1H-imidazole-4,5-dicarbonitrile....
Molecules, Vol. 25, Pages 313: Optimization of Ultrasonic Flavonoid Extraction from Saussurea involucrate, and the Ability of Flavonoids to Block Melanin Deposition in Human Melanocytes Molecules doi: 10.3390/molecules25020313 Authors: Chun-Yan Dai Pei-Ran Liao Ming-Zhuo Zhao Chao Gong Yue Dang Yuan Qu Li-Sha Qiu (1) Background: Flavonoids are the primary medicinal ingredient of Saussurea involucrate, which have significant antioxidant capacity. Optimizing the extraction...
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Nanomaterials, Vol. 10, Pages 145: Transition Metal Carbide Core/Shell Nanoparticles by Ultra-Short Laser Ablation in Liquid Nanomaterials doi: 10.3390/nano10010145 Authors: Angela De Bonis Mariangela Curcio Antonio Santagata Agostino Galasso Roberto Teghil Transition metal carbide nanoparticles are a class of technological interesting materials with a wide range of applications. Among metal carbides, tantalum carbides have good compatibility with the biological environment...
Nanomaterials, Vol. 10, Pages 144: The Effects of Metal Complexes of Nano-Graphene Oxide to Thermal Decomposition of FOX-7 Nanomaterials doi: 10.3390/nano10010144 Authors: Chongmin Zhang Xiaolong Fu Xuexue Zhang Jizhen Li Xuezhong Fan Guofang Zhang 1,1-diamino-2,2-dinitroethene (FOX-7) an insensitive high-energetic compound, has rarely been reported previously with respect to combustion performance. In order to quickly apply it to propellants, the thermal decomposition...
Nanomaterials, Vol. 10, Pages 140: Nanoparticles as Anti-Microbial, Anti-Inflammatory, and Remineralizing Agents in Oral Care Cosmetics: A Review of the Current Situation Nanomaterials doi: 10.3390/nano10010140 Authors: Florence Carrouel Stephane Viennot Livia Ottolenghi Cedric Gaillard Denis Bourgeois Many investigations have pointed out widespread use of medical nanosystems in various domains of dentistry such as prevention, prognosis, care, tissue regeneration, and restoration....
Nanomaterials, Vol. 10, Pages 142: Intrinsic Control in Defects Density for Improved ZnO Nanorod-Based UV Sensor Performance Nanomaterials doi: 10.3390/nano10010142 Authors: Abu ul Hassan Sarwar Rana Shoyebmohamad F. Shaikh Abdullah M. Al-Enizi Daniel Adjei Agyeman Faizan Ghani In Wook Nah Areej Shahid Hitherto, most research has primarily focused on improving the UV sensor efficiency via surface treatments and by stimulating the ZnO nanorod (ZNR) surface Schottky barriers....
Nanomaterials, Vol. 10, Pages 141: Characterisation of the PS-PMMA Interfaces in Microphase Separated Block Copolymer Thin Films by Analytical (S)TEM Nanomaterials doi: 10.3390/nano10010141 Authors: Julius Bürger Vinay S. Kunnathully Daniel Kool Jörg K. N. Lindner Katharina Brassat Block copolymer (BCP) self-assembly is a promising tool for next generation lithography as microphase separated polymer domains in thin films can act as templates for surface nanopatterning with...
Nanomaterials, Vol. 10, Pages 143: Evaluation of the Biodistribution of Serinolamide-Derivatized C60 Fullerene Nanomaterials doi: 10.3390/nano10010143 Authors: Nicholas G. Zaibaq Alyssa C. Pollard Michael J. Collins Federica Pisaneschi Mark D. Pagel Lon J. Wilson Carbon nanoparticles have consistently been of great interest in medicine. However, there are currently no clinical materials based on carbon nanoparticles, due to inconsistent biodistribution and excretion data....
Nanomaterials, Vol. 10, Pages 139: High-Quality Black Phosphorus Quantum Dots Fabricated via Microwave-Tailored Technology Nanomaterials doi: 10.3390/nano10010139 Authors: Kaixiang Du Wen Yang Shukang Deng Xueming Li Peizhi Yang Black phosphorus quantum dots (BPQDs) have recently obtained great attention due to their high mobility and tunable bandgap features, which are beneficial for their potential application in photoelectronic devices. However, a precise synthesis of...
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Nutrients, Vol. 12, Pages 212: Effects of Capsinoids on Daily Physical Activity, Body Composition and Cold Hypersensitivity in Middle-Aged and Older Adults: A Randomized Study Nutrients doi: 10.3390/nu12010212 Authors: Keiichi Yokoyama Yosuke Yamada Yasunori Akamatsu Yasuko Yoshinaka Akiko Yamamoto Tomonori Koizumi Kana Ohyama Katsuya Suzuki Masaki Hashimoto Hitoshi Sato Misaka Kimura Sedentary/inactive lifestyle leads middle-aged and older adults to metabolic...
Nutrients, Vol. 12, Pages 211: Sarcopenia and Heart Failure Nutrients doi: 10.3390/nu12010211 Authors: Francesco Curcio Gianluca Testa Ilaria Liguori Martina Papillo Veronica Flocco Veronica Panicara Gianluigi Galizia David Della-Morte Gaetano Gargiulo Francesco Cacciatore Domenico Bonaduce Francesco Landi Pasquale Abete Modifications of lean mass are a frequent critical determinant in the pathophysiology and progression of heart failure (HF). Sarcopenia...
Nutrients, Vol. 12, Pages 210: Modeling Possible Outcomes of Updated Daily Values on Nutrient Intakes of the United States Adult Population Nutrients doi: 10.3390/nu12010210 Authors: Newman McBurney Hunt Malek Marriott The United States (US) Food and Drug Administration has updated the Daily Values (DVs) for the Nutrition Facts Label on packaged foods. We used the National Health and Nutrition Examination Survey 2009–2012 data with the International Life Sciences...
Nutrients, Vol. 12, Pages 208: Impact of a Three-Week in-Hospital Multidisciplinary Body Weight Reduction Program on Body Composition, Muscle Performance and Fatigue in a Pediatric Obese Population with or without Metabolic Syndrome Nutrients doi: 10.3390/nu12010208 Authors: Rigamonti Tringali Micheli Col Tamini Saezza Cella Sartorio Metabolic syndrome is a combination of cardiometabolic risk factors, frequently detected in obese children and adolescents....
Nutrients, Vol. 12, Pages 209: Validation of a Deep Learning System for the Full Automation of Bite and Meal Duration Analysis of Experimental Meal Videos Nutrients doi: 10.3390/nu12010209 Authors: Konstantinidis Dimitropoulos Langlet Daras Ioakimidis Eating behavior can have an important effect on, and be correlated with, obesity and eating disorders. Eating behavior is usually estimated through self-reporting measures, despite their limitations in reliability, based...
Nutrients, Vol. 12, Pages 206: Relationship of Wine Consumption with Alzheimer’s Disease Nutrients doi: 10.3390/nu12010206 Authors: Reale Costantini Jagarlapoodi Khan Belwal Cichelli Background: Alzheimer’s disease (AD), the most threatening neurodegenerative disease, is characterized by the loss of memory and language function, an unbalanced perception of space, and other cognitive and physical manifestations. The pathology of AD is characterized by neuronal...
Nutrients, Vol. 12, Pages 205: Relationship Between the Gastrointestinal Side Effects of an Anti-Hypertensive Medication and Changes in the Serum Lipid Metabolome Nutrients doi: 10.3390/nu12010205 Authors: Ahn Nam Kim An earlier study using a rat model system indicated that the active ingredients contained in the anti-hypertensive medication amlodipine (AMD) appeared to induce various bowel problems, including constipation and inflammation. A probiotic blend was found to alleviate...
Nutrients, Vol. 12, Pages 207: The Nutritional and Micronutrient Status of Urban Schoolchildren with Moderate Anemia is Better than in a Rural Area in Kenya Nutrients doi: 10.3390/nu12010207 Authors: Esther Charlotte Evang Tsige-Yohannes Habte Willis Omondi Owino Michael Bernhardt Krawinkel Low diet quality is a driver of general and micronutrient malnutrition in urban and rural areas. The objective was to compare malnutrition and micronutrient deficiencies linked to dietary...
Nutrients, Vol. 12, Pages 204: Dietary Supplements: Which Place between Food and Drugs? Nutrients doi: 10.3390/nu12010204 Authors: Catherine Féart Healthy dietary habits and food choices, a part of lifestyle, are recognized as major environmental factors for the prevention of non-communicable chronic diseases over the life course; their modifiable features promise a reduced socio-economic global burden load in aging societies [...]
Nutrients, Vol. 12, Pages 203: Antibiotic Treatment Does Not Ameliorate the Metabolic Changes in Rats Presenting Dysbiosis After Consuming a High Fructose Diet Nutrients doi: 10.3390/nu12010203 Authors: Ariel Bier Rawan Khasbab Yael Haberman Tzipi Braun Rotem Hadar Katya Sosnovski Amnon Amir Avshalom Leibowitz Ehud Grossman High fructose consumption is one of the hallmarks of Western diets and has been found to induce MeS symptoms in parallel to gut microbial...
Nutrients, Vol. 12, Pages 201: Dietary Silk Peptide Prevents High-Fat Diet-Induced Obesity and Promotes Adipose Browning by Activating AMP-Activated Protein Kinase in Mice Nutrients doi: 10.3390/nu12010201 Authors: Kippeum Lee Heegu Jin Sungwoo Chei Jeong-Yong Lee Hyun-Ji Oh Boo-Yong Lee Obesity is associated with metabolic syndrome and other chronic diseases, and is caused when the energy intake is greater than the energy expenditure. We aimed to determine the mechanism...
Nutrients, Vol. 12, Pages 202: Menopause-Associated Lipid Metabolic Disorders and Foods Beneficial for Postmenopausal Women Nutrients doi: 10.3390/nu12010202 Authors: Seong-Hee Ko Hyun-Sook Kim Menopause is clinically diagnosed as a condition when a woman has not menstruated for one year. During the menopausal transition period, there is an emergence of various lipid metabolic disorders due to hormonal changes, such as decreased levels of estrogens and increased levels of circulating...
Nutrients, Vol. 12, Pages 200: Alcohol Consumption, Drinking Patterns, and Cognitive Performance in Young Adults: A Cross-Sectional and Longitudinal Analysis Nutrients doi: 10.3390/nu12010200 Authors: Henk Hendriks Ondine van de Rest Almar Snippe Jasper Kieboom Koen Hogenelst Long-term alcohol abuse is associated with poorer cognitive performance. However, the associations between light and moderate drinking and cognitive performance are less clear. We assessed this association...
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Pathogens, Vol. 9, Pages 56: Occurrence and Characterization of Salmonella Isolated from Table Egg Layer Farming Environments in Western Australia and Insights into Biosecurity and Egg Handling Practices Pathogens doi: 10.3390/pathogens9010056 Authors: Sodagari Habib Whiddon Wang Mohammed Robertson Goodchild The aim of this study was to investigate the occurrence and distribution of Salmonella in commercial layer farming environments of 26 flocks belonging to...
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Pharmaceuticals, Vol. 13, Pages 13: Sanguinarine Inhibits Mono- and Dual-Species Biofilm Formation by Candida albicans and Staphylococcus aureus and Induces Mature Hypha Transition of C. albicans Pharmaceuticals doi: 10.3390/ph13010013 Authors: Qian Wang Zhang Liu Fu Li Wang Li Previous studies have reported that sanguinarine possesses inhibitory activities against several microorganisms, but its effects on mono- and dual-species biofilms of C. albicans and...
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Pharmaceutics, Vol. 12, Pages 63: 3D Printing of Drug-Loaded Thermoplastic Polyurethane Meshes: A Potential Material for Soft Tissue Reinforcement in Vaginal Surgery Pharmaceutics doi: 10.3390/pharmaceutics12010063 Authors: Juan Domínguez-Robles Caterina Mancinelli Elena Mancuso Inmaculada García-Romero Brendan F. Gilmore Luca Casettari Eneko Larrañeta Dimitrios A. Lamprou Current strategies to treat pelvic organ prolapse (POP) or stress urinary incontinence (SUI),...
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Plants, Vol. 9, Pages 100: Chromium Bioaccumulation and Its Impacts on Plants: An Overview Plants doi: 10.3390/plants9010100 Authors: Sharma Kapoor Wang Shahzad Kumar Bali Jasrotia Zheng Yuan Yan Chromium (Cr) is an element naturally occurring in rocky soils and volcanic dust. It has been classified as a carcinogen agent according to the International Agency for Research on Cancer. Therefore, this metal needs an accurate understanding and thorough...
Plants, Vol. 9, Pages 101: Ascorbate and Thiamin: Metabolic Modulators in Plant Acclimation Responses Plants doi: 10.3390/plants9010101 Authors: Rosado-Souza Fernie Aarabi Cell compartmentalization allows incompatible chemical reactions and localised responses to occur simultaneously, however, it also requires a complex system of communication between compartments in order to maintain the functionality of vital processes. It is clear that multiple such signals must exist, yet...
Plants, Vol. 9, Pages 99: Genomic Predictions Using Low-Density SNP Markers, Pedigree and GWAS Information: A Case Study with the Non-Model Species Eucalyptus cladocalyx Plants doi: 10.3390/plants9010099 Authors: Paulina Ballesta David Bush Fabyano Fonseca Silva Freddy Mora High-throughput genotyping techniques have enabled large-scale genomic analysis to precisely predict complex traits in many plant species. However, not all species can be well represented in commercial SNP...
Plants, Vol. 9, Pages 98: Comparison of Organosulfur and Amino Acid Composition between Triploid Onion Allium cornutum Clementi ex Visiani, 1842, and Common Onion Allium cepa L., and Evidences for Antiproliferative Activity of Their Extracts Plants doi: 10.3390/plants9010098 Authors: Željana Fredotović Barbara Soldo Matilda Šprung Zvonimir Marijanović Igor Jerković Jasna Puizina Species that belong to the genus Allium have been widely used for human food and traditional...
Plants, Vol. 9, Pages 97: Current Progress in Nitrogen Fixing Plants and Microbiome Research Plants doi: 10.3390/plants9010097 Authors: Kishan Mahmud Shiva Makaju Razi Ibrahim Ali Missaoui In agroecosystems, nitrogen is one of the major nutrients limiting plant growth. To meet the increased nitrogen demand in agriculture, synthetic fertilizers have been used extensively in the latter part of the twentieth century, which have led to environmental challenges such as nitrate pollution....
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Religions, Vol. 11, Pages 43: ‘Moderate Islam’ Made in the United Arab Emirates: Public Diplomacy and the Politics of Containment Religions doi: 10.3390/rel11010043 Authors: Kourgiotis This essay addresses the ideological utilization of religion in the international relations of the United Arab Emirates during the Arab Spring and beyond. By referring to the theoretical framework of public diplomacy and analyzing UAE regional and domestic attitudes, this essay intends to examine the...
Religions, Vol. 11, Pages 42: ‘Go and Prophesy in Your Own Land’: Foreign Prophets and Popularism in South Africa. Evoking the Need of Jonathanic Theology for Peaceful Resolution of Difference Religions doi: 10.3390/rel11010042 Authors: Bekithemba Dube Informed by a decoloniality lens and referencing motifs such as coloniality of power, knowledge, and being, this theoretical article analyses and problematises conflict, and reconstructs the experience of foreign and local prophets in...
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Robotics, Vol. 9, Pages 5: A Review of the Literature on the Lower-Mobility Parallel Manipulators of 3-UPU or 3-URU Type Robotics doi: 10.3390/robotics9010005 Authors: Raffaele Di Gregorio Various 3-UPU architectures feature two rigid bodies connected to one another through three kinematic chains (limbs) of universal–prismatic–universal (UPU) type. They were first proposed in the last decade of the 20th century and have animated discussions among researchers for more-or-less...
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Sci, Vol. 2, Pages 3: Differentiation of Heterogeneous Mouse Liver from HCC by Hyperpolarized 13C Magnetic Resonance Sci doi: 10.3390/sci2010003 Authors: Naama Lev-Cohain Gal Sapir Sivaranjan Uppala Atara Nardi-Schreiber Shraga Nahum Goldberg Yael Adler-Levy Jacob Sosna J. Moshe Gomori Rachel Katz-Brull The clinical characterization of small hepatocellular carcinoma (HCC) lesions in the liver and differentiation from heterogeneous inflammatory or fibrotic background...
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Societies, Vol. 10, Pages 8: Spatial Equity in Urban Public Space (UPS) Based on Analysis of Municipal Public Policy Omissions: A Case Study of Atizapán de Zaragoza, State of México Societies doi: 10.3390/soc10010008 Authors: Elsa A. Pérez-Paredes Aleksandra Krstikj International agendas, such as the 2030 Sustainable Development Goals, have been established as global guidelines for equitable planning of urban centers. However, there is a lack of indicators and tools for public policy...
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Technologies, Vol. 8, Pages 6: A TensorFlow Extension Framework for Optimized Generation of Hardware CNN Inference Engines Technologies doi: 10.3390/technologies8010006 Authors: Vasileios Leon Spyridon Mouselinos Konstantina Koliogeorgi Sotirios Xydis Dimitrios Soudris Kiamal Pekmestzi The workloads of Convolutional Neural Networks (CNNs) exhibit a streaming nature that makes them attractive for reconfigurable architectures such as the Field-Programmable Gate Arrays (FPGAs),...
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Toxins, Vol. 12, Pages 46: Cellular Effects of T-2 Toxin on Primary Hepatic Cell Culture Models of Chickens Toxins doi: 10.3390/toxins12010046 Authors: Máté Mackei Kata Orbán Andor Molnár László Pál Károly Dublecz Ferenc Husvéth Zsuzsanna Neogrády Gábor Mátis Trichothecene mycotoxins such as T-2 toxin cause severe problems for agriculture, as well as for veterinary medicine. As liver is one of the key organs in metabolism, the main aim of our study was to investigate...
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Vaccines, Vol. 8, Pages 24: Cross-Protection Induced by a A/MAY/97 Emergency Vaccine Against Intra-Serotype Heterologous Challenge with a Foot-and-Mouth Disease Virus from the A/ASIA/G-VII Lineage Vaccines doi: 10.3390/vaccines8010024 Authors: Aldo Dekker Beatriz Sanz-Bernardo Nagendrakumar Balasubramanian Singanallur Anna B. Ludi Jacquelyn Horsington Phaedra L. Eblé Donald P. King Wilna Vosloo Since 2015, outbreaks of foot-and-mouth disease (FMD) in the Middle East...
Vaccines, Vol. 8, Pages 23: Polyacrylate–Peptide Antigen Conjugate as a Single-Dose Oral Vaccine against Group A Streptococcus Vaccines doi: 10.3390/vaccines8010023 Authors: Mohammad Omer Faruck Lili Zhao Waleed M. Hussein Zeinab G. Khalil Robert J. Capon Mariusz Skwarczynski Istvan Toth Group A Streptococcus (GAS)-associated rheumatic heart disease is a leading cause of death caused by GAS infection. While antibiotics can treat the infection in most cases, growing...
Vaccines, Vol. 8, Pages 22: Autophagy Promotes Duck Tembusu Virus Replication by Suppressing p62/SQSTM1-Mediated Innate Immune Responses In Vitro Vaccines doi: 10.3390/vaccines8010022 Authors: Zhiqiang Hu Yuhong Pan Anchun Cheng Xingcui Zhang Mingshu Wang Shun Chen Dekang Zhu Mafeng Liu Qiao Yang Ying Wu Xinxin Zhao Juan Huang Shaqiu Zhang Sai Mao Xumin Ou Yanling Yu Ling Zhang Yunya Liu Bin Tian Leichang Pan Mujeeb Ur Rehman Zhongqiong...
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Veterinary Sciences, Vol. 7, Pages 9: Investigation of Melioidosis Outbreak in Pig Farms in Southern Thailand Veterinary Sciences doi: 10.3390/vetsci7010009 Authors: Wiyada Kwanhian Treenate Jiranantasak Aleeza T. Kessler Bryn E. Tolchinsky Sarah Parker Jirarat Songsri Suebtrakool Wisessombat Kawinsaya Pukanha Vincentius A. Testamenti Pacharapong Khrongsee Somporn Sretrirutchai Jedsada Kaewrakmuk Jitbanjong Tangpong Apichai Tuanyok Melioidosis,...
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Viruses, Vol. 12, Pages 93: Special Issue “Human Picornaviruses” Viruses doi: 10.3390/v12010093 Authors: Susi The Special Issue “Human Picornaviruses” in “Viruses” (Submission Deadline 30 September 2019, https://www.mdpi.com/journal/viruses/special_issues/Picornaviruses) includes twelve original articles and four reviews with a wide range of topics [...]
Viruses, Vol. 12, Pages 91: Single Amino Acid Substitutions in the Cucumber Mosaic Virus 1a Protein Induce Necrotic Cell Death in Virus-Inoculated Leaves without Affecting Virus Multiplication Viruses doi: 10.3390/v12010091 Authors: Ainan Tian Shuhei Miyashita Sugihiro Ando Hideki Takahashi When Arabidopsis thaliana ecotype Col-0 was inoculated with a series of reassortant viruses created by exchanging viral genomic RNAs between two strains of cucumber mosaic virus (CMV), CMV(Y),...
Viruses, Vol. 12, Pages 92: Characterization of Ebola Virus Disease (EVD) in Rhesus Monkeys for Development of EVD Therapeutics Viruses doi: 10.3390/v12010092 Authors: Travis Warren Elizabeth Zumbrun Jessica M. Weidner Laura Gomba Franco Rossi Roy Bannister Jacqueline Tarrant Matthew Reed Eric Lee Jo Lynne Raymond Jay Wells Joshua Shamblin Kelly Wetzel Ginger Donnelly Sean Van Tongeren Nicole Lackemeyer Jesse Steffens Adrienne Kimmel Carly...
Viruses, Vol. 12, Pages 90: Glycine Cleavage System and cAMP Receptor Protein Co-Regulate CRISPR/cas3 Expression to Resist Bacteriophage Viruses doi: 10.3390/v12010090 Authors: Denghui Yang Zhaofei Wang Jingjiao Ma Qiang Fu Lifei Wu Hengan Wang Shaohui Wang Yaxian Yan Jianhe Sun The CRISPR/Cas system protects bacteria against bacteriophage and plasmids through a sophisticated mechanism where cas operon plays a crucial role consisting of cse1 and cas3. However,...
Viruses, Vol. 12, Pages 89: Epidemiology and Clinical Characteristics of Influenza C Virus Viruses doi: 10.3390/v12010089 Authors: Bethany K. Sederdahl John V. Williams Influenza C virus (ICV) is a common yet under-recognized cause of acute respiratory illness. ICV seropositivity has been found to be as high as 90% by 7–10 years of age, suggesting that most people are exposed to ICV at least once during childhood. Due to difficulty detecting ICV by cell culture, epidemiologic...
Viruses, Vol. 12, Pages 88: Detection of a Reassortant H9N2 Avian Influenza Virus with Intercontinental Gene Segments in a Resident Australian Chestnut Teal Viruses doi: 10.3390/v12010088 Authors: Tarka Raj Bhatta Anthony Chamings Jessy Vibin Marcel Klaassen Soren Alexandersen The present study reports the genetic characterization of a low-pathogenicity H9N2 avian influenza virus, initially from a pool and subsequently from individual faecal samples collected from Chestnut...
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Water, Vol. 12, Pages 224: Assessing the Impact of Climate Change on Groundwater Quality of the Shallow Coastal Aquifer of Eastern Dahomey Basin, Southwestern Nigeria Water doi: 10.3390/w12010224 Authors: Jamiu A. Aladejana Robert M. Kalin Philippe Sentenac Ibrahim Hassan Despite the increasing interest in climate change and water security, research linking climate change and groundwater quality is still at an early stage. This study explores the seasonal effect of the change...
Water, Vol. 12, Pages 222: Study on Runoff and Infiltration for Expansive Soil Slopes in Simulated Rainfall Water doi: 10.3390/w12010222 Authors: Lei Dong Chen Lv Fan Mei In order to understand the hydrological process of expansive soil slopes, simulated rainfall experiments were conducted to study the effects of slope gradient and initial soil moisture content on runoff and infiltration for expansive soil slopes located in south China. The field program consisted...
Water, Vol. 12, Pages 223: Experimental Investigation of Substrate Shock and Environmental Ammonium Concentration on the Stability of Ammonia-Oxidizing Bacteria (AOB) Water doi: 10.3390/w12010223 Authors: Keerio Bae A wastewater treatment plant (WWTP) frequently encounters fluctuation in ammonium concentration or flow rate (Q), which may affect the stability of ammonium oxidizing bacteria (AOB). In this study, two continuous stirred tank reactors (CSTRs) were operated for 588 days...
Water, Vol. 12, Pages 219: Potential Impacts of Future Climate Change Scenarios on Ground Subsidence
Water, Vol. 12, Pages 219: Potential Impacts of Future Climate Change Scenarios on Ground Subsidence Water doi: 10.3390/w12010219 Authors: Collados-Lara Pulido-Velazquez Mateos Ezquerro In this work, we developed a new method to assess the impact of climate change (CC) scenarios on land subsidence related to groundwater level depletion in detrital aquifers. The main goal of this work was to propose a parsimonious approach that could be applied for any case study. We also...
Water, Vol. 12, Pages 220: Modeling River Ice Breakup Dates by k-Nearest Neighbor Ensemble Water doi: 10.3390/w12010220 Authors: Sun Lv Li Chen Forecasting of river ice breakup timing is directly related to the local ice-caused flooding management. However, river ice forecasting using k-nearest neighbor (kNN) algorithms is limited. Thus, a kNN stacking ensemble learning (KSEL) method was developed and applied to forecasting breakup dates (BDs) for the Athabasca River at...
Water, Vol. 12, Pages 221: An Agricultural Interval Two-Stage Fuzzy Differential Water Price Model (ITS-DWPM) for Initial Water Rights Allocation in Hulin, China Water doi: 10.3390/w12010221 Authors: Shuo Yan Liquan Wang Tienan Li In recent years, China’s agricultural water consumption has been high, while water inefficiency has restricted the development of the economy. In this study, we developed an agricultural interval two-stage fuzzy differential water prices model...
Water, Vol. 12, Pages 218: Formulation and Characterization of a Heterotrophic Nitrification-Aerobic Denitrification Synthetic Microbial Community and its Application to Livestock Wastewater Treatment Water doi: 10.3390/w12010218 Authors: Qi-yu Zhang Ping Yang Lai-sheng Liu Zeng-jin Liu There have been many studies on single strains in wastewater treatment and a new synthetic microbial community was prepared in this study, which provides a reference for the application of heterotrophic...
Water, Vol. 12, Pages 217: Effect of Water Deficit on Morphoagronomic and Physiological Traits of Common Bean Genotypes with Contrasting Drought Tolerance Water doi: 10.3390/w12010217 Authors: Leonardo Godoy Androcioli Douglas Mariani Zeffa Daniel Soares Alves Juarez Pires Tomaz Vânia Moda-Cirino Water deficit is considered one of the most limiting factors of the common bean. Understanding the adaptation mechanisms of the crop to this stress is fundamental for the development...
Water, Vol. 12, Pages 216: Streamflow Intensification Driven by the Atlantic Multidecadal Oscillation (AMO) in the Atrato River Basin, Northwestern Colombia Water doi: 10.3390/w12010216 Authors: Wilmar Loaiza Cerón Mary Toshie Kayano Rita Valeria Andreoli Alvaro Avila Teresita Canchala Félix Francés Irma Ayes Rivera Wilfredo Alfonso-Morales Rodrigo Augusto Ferreira de Souza Yesid Carvajal-Escobar The impact of the Atlantic Multidecadal Oscillation (AMO) on...
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