Identifying challenges to implementation of clinical practice guidelines for sentinel lymph node biopsy in patients with melanoma in Australia: protocol paper for a mixed methods study: Introduction
Sentinel lymph node biopsy (SLNB) is a diagnostic procedure developed in the 1990s. It is currently used to stage patients with primary cutaneous melanoma, provide prognostic information and guide management. The Australian Clinical Practice Guidelines state that SLNB should be considered for patients with cutaneous melanoma >1 mm in thickness (or >0.8 mm with high-risk pathology features). Until recently, sentinel lymph node (SLN) status was used to identify patients who might benefit from a completion lymph node dissection, a procedure that is no longer routinely recommended. SLN status is now also being used to identify patients who might benefit from systemic adjuvant therapies such as anti-programmed cell death 1 (PD1) checkpoint inhibitor immunotherapy or BRAF-directed molecular targeted therapy, treatments that have significantly improved relapse-free survival for patients with resected stage III melanoma and improved overall survival of patients with unresectable stage III and stage IV melanoma. Australian and international data indicate that approximately half of eligible patients receive an SLNB.
Methods and analysis
This mixed-methods study seeks to understand the structural, contextual and cultural factors affecting implementation of the SLNB guidelines. Data collection will include: (1) cross-sectional questionnaires and semistructured interviews with general practitioners and dermatologists; (2) semistructured interviews with other healthcare professionals involved in the diagnosis and early definitive care of melanoma patients and key stakeholders including researchers, representatives of professional colleges, training organisations and consumer melanoma groups; and (3) documentary analysis of documents from government, health services and non-government organisations. Descriptive analyses and multivariable regression models will be used to examine factors related to SLNB practices and attitudes. Qualitative data will be analysed using thematic analysis.
Ethics and dissemination
Ethics approval has been granted by the University of Sydney. Results will be disseminated through publications and presentations to clinicians, patients, policymakers and researchers and will inform the development of strategies for implementing SLNB guidelines in Australia.
Medicine RSS-Feeds by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com
Πληροφορίες
Πέμπτη 27 Φεβρουαρίου 2020
Identifying challenges to implementation of clinical practice guidelines for sentinel lymph node biopsy in patients with melanoma in Australia: protocol paper for a mixed methods study
Αναρτήθηκε από
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
στις
10:43 μ.μ.
Ετικέτες
00302841026182,
00306932607174,
alsfakia@gmail.com,
Anapafseos 5 Agios Nikolaos 72100 Crete Greece,
Medicine by Alexandros G. Sfakianakis,
Telephone consultation 11855 int 1193
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
Αρχειοθήκη ιστολογίου
-
►
2023
(366)
- ► Φεβρουαρίου (184)
- ► Ιανουαρίου (182)
-
►
2022
(2814)
- ► Δεκεμβρίου (182)
- ► Σεπτεμβρίου (213)
- ► Φεβρουαρίου (264)
- ► Ιανουαρίου (262)
-
►
2021
(3815)
- ► Δεκεμβρίου (229)
- ► Σεπτεμβρίου (276)
- ► Φεβρουαρίου (64)
-
▼
2020
(5754)
- ► Δεκεμβρίου (401)
- ► Σεπτεμβρίου (365)
-
▼
Φεβρουαρίου
(754)
-
▼
Φεβ 27
(74)
- Medicine by Alexandros G. Sfakianakis,Anapafseos 5...
- Real‐time near‐infrared fluorescence imaging media...
- Identifying challenges to implementation of clinic...
- Blaschkoid lichen planus occurring in childhood sy...
- Deep forehead lipomas in children—A series and review
- Hypergammaglobulinemic purpura of Waldenström in c...
- Psychotropic Drug-Associated Pneumonia in Older Ad...
- Benzodiazepine Prescribing in People with Chronic ...
- Old weapon, new target: Dasatinib against angioimm...
- Nutritional outcomes after radiotherapy target vol...
- Microbiota as Predictor of Mortality in Allogeneic...
- A candidate probiotic strain of Enterococcus faeci...
- Medical Treatment of Gastrointestinal Neuroendocri...
- Impact of corticosteroid treatment on clinical out...
- Prevent action of magnoflorine with hyaluronic aci...
- Neuroprotective effects of saffron on the late cer...
- Coordination of tongue pressure production, hyoid ...
- [Effect of electronic moxibustion on activity of p...
- Adverse reaction to local anaesthetics: is it alwa...
- Repertoire of peripheral T cells in patients with ...
- What is the optimal timing for implant placement i...
- Inflammatory Mediators in Saliva and Gingival Flui...
- Banded versus modified appliances for anchorage du...
- Postoperative delirium after reconstructive surger...
- Maxillomandibular advancement for the treatment of...
- Maintaining the anterior superior iliac spine (ASI...
- Density of the mandibular ramus (cancellous:cortic...
- Identification of a potential target for treatment...
- Characteristics of neutrophil extracellular traps ...
- The effectiveness of olopatadine hydrochloride eye...
- Transcriptomic and epigenetic regulation of hair c...
- Evaluation of video compression methods for cone-b...
- Recurrence of linear basal cell carcinoma.
- Peripheral dentinogenic ghost cell tumor of the et...
- Natural History and Management of Familial Paragan...
- Molecular Diagnostics in Human Papillomavirus-Rela...
- Small Molecule Binds with Lymphocyte Antigen 6K to...
- Usefulness of Hybrid PET/MRI in Clinical Evaluatio...
- Perioperative nasal and paranasal sinus considerat...
- Incidence and malignant transformation of glottic ...
- Thyroid Cancer Incidence Trends in the United Stat...
- Nuocytes from mesenteric lymph node promote allerg...
- Daily Time of Radiation Treatment is Associated wi...
- Genipin Induces Autophagy and Suppresses Cell Grow...
- From Anemia to Erythropoietin Resistance in Head a...
- Prognosis Value of Platelet Counts, Albumin and Ne...
- Successful Treatment of a Mixed Neuroendocrine-Non...
- Drug hypersensitivity reactions in Asia: regional ...
- Asia Pacific Association of Allergy Asthma and Cli...
- Tumor control of cervical lymph node metastases of...
- The vascularized fascia lata free flap: an anatomi...
- Integrin ανβ6 Protein Expression and Prognosis in ...
- Salivary biomarkers in the context of gingival inf...
- Down-regulation of anti-inflammatory TIPE2 may agg...
- Sterile traumatic panniculitis in a captive Brent ...
- MiR-214 Mediates Cell Proliferation and Apoptosis ...
- Biallelic TANGO1 mutations cause a novel syndromal...
- Risk factors for human papillomavirus-positive non...
- Oral squamous cell carcinoma involving the maxilla...
- Scarless Neck Feminization: Transoral Transvestibu...
- Video Standards for Rhinoplasty Education: A Revie...
- Benefit from surgery with additional radiotherapy ...
- Frey syndrome-like developmental dysautonomia in a...
- Robotic neck dissection: state of affairs.
- The vessel-depleted neck in head and neck microvas...
- Electrochemotherapy in the head and neck area: an ...
- Current opinion in otolaryngology and head and nec...
- The use of 3D virtual surgical planning and comput...
- PRO/AH/EDR> E. coli EHEC - USA (02): O103, sprouts...
- PRO/EDR> Scombroid fish poisoning - Canada: tuna, ...
- PRO/PL> Greening disease, citrus - El Salvador: alert
- PRO/AH/EDR> Equine herpesvirus - North America (03...
- Radiologic analysis of the location, shape and siz...
- Cavernous sinus and abducens nerve in human fetuse...
-
▼
Φεβ 27
(74)
- ► Ιανουαρίου (894)
-
►
2019
(146)
- ► Δεκεμβρίου (19)
- ► Σεπτεμβρίου (54)
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου