Related Articles Analysis of Differential Expression of Synaptic Vesicle Protein 2A in the Adult Rat Brain. Neuroscience. 2019 11 01;419:108-120 Authors: Mendoza-Torreblanca JG, García-Cruz ME, Sánchez-Cruz I, Gomez-Gonzalez B, Juárez-Méndez S, Gómez-Lira G Abstract Synaptic vesicle protein 2A (SV2A), which plays an important role in the pathophysiology of epilepsy, is a unique vesicular protein recognized as a pharmacological target of anticonvulsant...
Thu Sep 24, 2020 14:54
Related Articles Adenosine Receptor Ligands: Coumarin-Chalcone Hybrids as Modulating Agents on the Activity of hARs. Molecules. 2020 Sep 19;25(18): Authors: Vazquez-Rodriguez S, Vilar S, Kachler S, Klotz KN, Uriarte E, Borges F, Matos MJ Abstract Adenosine receptors (ARs) play an important role in neurological and psychiatric disorders such as Alzheimer's disease, Parkinson's disease, epilepsy and schizophrenia. The different subtypes of ARs...
Thu Sep 24, 2020 14:54
Related Articles Barriers to biomedical care for people with epilepsy in Uganda: A cross-sectional study. Epilepsy Behav. 2020 Sep 19;:107349 Authors: Kaddumukasa MN, Kaddumukasa M, Kajumba M, Smith PJ, Bobholz S, Kakooza-Mwesige A, Sinha DD, Almojuela A, Chakraborty P, Nakasujja N, Nakku J, Gualtieri A, Onuoha E, Kolls BJ, Muhumuza C, Smith CE, Sanchez N, Fuller AT, Haglund MM, Koltai DC Abstract OBJECTIVE: Epilepsy, a neurological disorder...
Thu Sep 24, 2020 14:54
Related Articles Therapeutic effects of rosemary (Rosmarinus officinalis L.) and its active constituents on nervous system disorders. Iran J Basic Med Sci. 2020 Sep;23(9):1100-1112 Authors: Ghasemzadeh Rahbardar M, Hosseinzadeh H Abstract Rosemary (Rosmarinus officinalis L.) is an evergreen bushy shrub which grows along the Mediterranean Sea, and sub-Himalayan areas. In folk medicine, it has been used as an antispasmodic, mild analgesic, to...
Thu Sep 24, 2020 14:54
The prevalence of comorbidities in patients with multiple sclerosis: population-based registry data.
Related Articles The prevalence of comorbidities in patients with multiple sclerosis: population-based registry data. Neurol Sci. 2020 Sep 22;: Authors: Maric GD, Pekmezovic TD, Mesaros ST, Tamas OS, Ivanovic JB, Martinovic VN, Andabaka MM, Jovanovic AL, Veselinovic ND, Kisic-Tepavcevic DB, Drulovic JS Abstract BACKGROUND: Comorbidities occur frequently in persons with multiple sclerosis (MS). The aim of the present study was to determine the...
Thu Sep 24, 2020 14:54
Related Articles Epilepsy syndromes, etiologies, and the use of next-generation sequencing in epilepsy presenting in the first 2 years of life: A population-based study. Epilepsia. 2020 Sep 23;: Authors: Stödberg T, Tomson T, Barbaro M, Stranneheim H, Anderlid BM, Carlsson S, Åmark P, Wedell A Abstract OBJECTIVE: Population-based data on epilepsy syndromes and etiologies in early onset epilepsy are scarce. The use of next-generation sequencing...
Thu Sep 24, 2020 14:54
Related Articles Protocol for a single patient therapy plan: A randomised, double-blind, placebo-controlled N-of-1 trial to assess the efficacy of cannabidiol in patients with intractable epilepsy. J Paediatr Child Health. 2020 Sep 23;: Authors: Ong KS, Carlin JB, Fahey M, Freeman JL, Scheffer IE, Gillam L, Anderson M, Huque MH, Legge D, Dirnbauer N, Lilley B, Slota-Kan S, Cranswick N Abstract AIM: This paper describes the use of the single...
Thu Sep 24, 2020 14:54
Related Articles Altered amplitude of low-frequency fluctuations and regional homogeneity in drug-resistant epilepsy patients with vagal nerve stimulators under different current intensity. CNS Neurosci Ther. 2020 Sep 23;: Authors: Zhu J, Xu C, Zhang X, Qiao L, Wang X, Zhang X, Yan X, Ni D, Yu T, Zhang G, Li Y Abstract BACKGROUND: The mechanisms of vagal nerve stimulation (VNS) for the treatment of drug-resistant epilepsy (DRE) remain unclear....
Thu Sep 24, 2020 14:54
Related Articles Potential role of brivaracetam in paediatric epilepsy. Acta Neurol Scand. 2020 Sep 23;: Authors: Verrotti A, Grasso EA, Cacciatore M, Mastricardi S, Striano P Abstract Brivaracetam (BRV) is a new antiseizure medication (ASM) that is currently approved for adjunctive treatment in patients with focal onset seizures. Similarly to Levetiracetam (LEV), BRV works by binding SV2A vesicles with a high affinity and a linear pharmacokinetic...
Thu Sep 24, 2020 14:54
Related Articles Dynamic hip kinematics before and after periacetabular osteotomy in patients with dysplasia. J Orthop Sci. 2020 Mar;25(2):247-254 Authors: Yoshimoto K, Hamai S, Higaki H, Gondoh H, Shiomoto K, Ikebe S, Hara D, Komiyama K, Nakashima Y Abstract BACKGROUND: We prospectively analyzed the hip kinematics in patients with developmental dysplasia of the hip (DDH) before and after periacetabular osteotomy (PAO) and in healthy subjects...
Thu Sep 24, 2020 14:55
Related Articles Early fiberoptic endoscopic evaluation of swallow in transoral robotic surgery: Description of swallow function and recovery in the acute postoperative period for oropharyngeal squamous cell carcinoma. Head Neck. 2020 Sep 16;: Authors: Charters EK, Bogaardt H, Freeman-Sanderson AL, Ballard KJ, Davies S, Oates J, Clark J Abstract BACKGROUND: Transoral robotic surgery (TORS) is a minimally invasive approach for the treatment of...
Thu Sep 24, 2020 14:55
Related Articles Mortality and morbidity in obstructive sleep apnoea-hypopnoea syndrome: results from a 30-year prospective cohort study. ERJ Open Res. 2020 Jul;6(3): Authors: Dodds S, Williams LJ, Roguski A, Vennelle M, Douglas NJ, Kotoulas SC, Riha RL Abstract Background: Obstructive sleep apnoea-hypopnoea syndrome (OSAHS) carries substantial negative health consequences. This study examines factors affecting mortality and morbidity according...
Thu Sep 24, 2020 14:55
Related Articles Improving CPAP Adherence for Obstructive Sleep Apnea: A Practical Application Primer on CPAP Desensitization. MedEdPORTAL. 2020 Sep 15;16:10963 Authors: Chernyak Y Abstract Introduction: Obstructive sleep apnea (OSA) is a common medical condition with well-established morbidity and mortality. Continuous positive airway pressure (CPAP) is a highly effective treatment prescribed to most individuals with OSA that has documented...
Thu Sep 24, 2020 14:55
Related Articles Impact of histaminergic H3 receptor antagonist on hypoglossal nucleus in chronic intermittent hypoxia conditions. Psychopharmacology (Berl). 2020 Sep 22;: Authors: Xie L, Wu Q, Hu W, Wu X, Xiang G, Hao S, Guo H, Li S Abstract RATIONALE: The hypoglossal nucleus (HN) controls the movement of the genioglossus (GG) muscle whose dysfunction leads to airway occlusion and occurrence of obstructive sleep apnea (OSA). Histamine produced...
Thu Sep 24, 2020 14:55
Related Articles The impact of the COVID-19 pandemic on sleep medicine practices. J Clin Sleep Med. 2020 Sep 23;: Authors: Johnson KG, Sullivan SS, Nti A, Rastegar V, Gurubhagavatula I Abstract STUDY OBJECTIVES: The COVID-19 pandemic required sleep centers to consider and implement infection control strategies to mitigate viral transmission to patients and staff. Our aim was to assess measures taken by sleep centers due to the COVID-19 pandemic...
Thu Sep 24, 2020 14:55
Related Articles The treatment of mild OSA with CPAP or mandibular advancement device and the effect on blood pressure and endothelial function after one year of treatment. J Clin Sleep Med. 2020 Sep 23;: Authors: Guimarães TM, Poyares D, Oliveira E Silva L, Luz G, Coelho G, Fabbro CD, Tufik S, Bittencourt L Abstract STUDY OBJECTIVES: To evaluate and compare the effects of continuous positive airway pressure (CPAP), use of a mandibular advancement...
Thu Sep 24, 2020 14:55
Related Articles Large scale assessment of consistency in sleep stage scoring rules among multiple sleep centers using an interpretable machine learning algorithm. J Clin Sleep Med. 2020 Sep 23;: Authors: Liu GR, Lin TY, Wu HT, Sheu YC, Liu CL, Liu WT, Yang MC, Ni YL, Chou KT, Chen CH, Wu D, Lan CC, Chiu KL, Chiu HY, Lo YL Abstract STUDY OBJECTIVES: Polysomnography is the gold standard in identifying sleep stages; however, there are discrepancies...
Thu Sep 24, 2020 14:55
Related Articles The influence of opioids and non-opioid central nervous system active medications on central sleep apnea: a case-control study. J Clin Sleep Med. 2020 Sep 23;: Authors: Gavidia R, Emenike A, Meng A, Jansen EC, Hershner S, Goldstein C, Fetterolf J, Dunietz GL Abstract STUDY OBJECTIVES: Opioids are known to contribute to central sleep apnea (CSA), but the influence of non-opioid central nervous system active medications (CNSAM)...
Thu Sep 24, 2020 14:55
Related Articles Determinants of bilevel therapy in the management of obstructive sleep apnea. Sleep Breath. 2020 Sep 23;: Authors: Shah S, Smotherman C, Louis M Abstract BACKGROUND: The aim of this study was to investigate potential patient or polysomnogram (PSG) characteristics that can help determine who might benefit from bilevel positive airway pressure (BPAP) in the treatment of uncomplicated OSA. STUDY DESIGN: This was a single...
Thu Sep 24, 2020 14:55
Related Articles Sex differences in integrated neuro-cardiovascular control of blood pressure following acute intermittent hypercapnic-hypoxia. Am J Physiol Regul Integr Comp Physiol. 2020 Sep 23;: Authors: Jacob DW, Ott EP, Baker SE, Scruggs ZM, Ivie CL, Harper JL, Manrique-Acevedo CM, Limberg JK Abstract Repetitive hypoxic apneas, similar to that observed in sleep apnea, result in resetting of the sympathetic baroreflex to higher blood pressures...
Thu Sep 24, 2020 14:55
Related Articles Treatment of snoring and sleep apnea with a tongue rehabilitation device. J Clin Orthod. 2020 Jul;54(7):400-409 Authors: Feitoza CC, Coelho N, Costa N, Ponte A, Azevedo W PMID: 32966245 [PubMed - as supplied by publisher]
Thu Sep 24, 2020 14:55
25 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/09/24PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Thu Sep 24, 2020 15:00
Related Articles Progress in Studies on Structural and Remedial Aspects of Newly Born Coronavirus, SARS-CoV-2. Curr Top Med Chem. 2020 Sep 22;: Authors: Gupta SP Abstract The article highlights an up-to-date progress in studies of structure and the remedial aspects of novel coronavirus 2019-nCoV, renamed as SARS-CoV-2, leading to the disease COVID-19, a pandemic. In general, all CoVs including SARSCoV-2 are spherical positive single-stranded...
Thu Sep 24, 2020 15:22
Related Articles Nanomedicine and early cancer diagnosis: molecular imaging using fluorescence nanoparticles. Curr Top Med Chem. 2020 Sep 22;: Authors: Jin KT, Yao JY, Ying XJ, Lin Y, Chen YF Abstract Incorporating nanotechnology into fluorescent imaging and magnetic resonance imaging (MRI) has shown promising potentials for accurate diagnosis of cancer at earlier stage than the conventional imaging modalities. Molecular imaging (MI) aims to...
Thu Sep 24, 2020 15:22
Related Articles Membrane derived Vesicles as Biomimetic Carriers for Targeted Drug Delivery system. Curr Top Med Chem. 2020 Sep 22;: Authors: Zhang LY, Yang X, Wang SB, Chen H, Pan HY, Hu ZM Abstract Extracellular vesicles (EVs) are membrane vesicles (MVs) serving important roles in various cellular and molecular functions in cell-to-cell signaling and transmitting molecular signals to adjacent as well as distant cells. The preserved cell membrane...
Thu Sep 24, 2020 15:22
Related Articles Exploring µ-Opioid Receptor Splice Variants as Specific Molecular Target for New Analgesics. Curr Top Med Chem. 2020 Sep 22;: Authors: Mizoguchi H, Fujii H Abstract Since an µ-opioid receptor gene containing the multiple exons has been identified, the variety of splice variants for µ-opioid receptors have been reported in various species. Amidino-TAPA and IBNtxA have been discovered as new analgesics with different pharmacological...
Thu Sep 24, 2020 15:22
Related Articles Hyaluronan based Multifunctional Nano-carriers for Combination Cancer Therapy. Curr Top Med Chem. 2020 Sep 22;: Authors: Gao M, Deng H, Zhang W Abstract Hyaluronan (HA) is a natural linear polysaccharide that has excellent hydrophilicity, biocompatibility, biodegradability, and low immunogenicity, making it one of the most attractive biopolymers used for biomedical researches and applications. Due to the multiple functional...
Thu Sep 24, 2020 15:22
Related Articles Nanoscale Drug Delivery Systems for Glaucoma: Experimental and In Silico Advances. Curr Top Med Chem. 2020 Sep 22;: Authors: Sharma S, Bhatia V Abstract In this review nanoscale based drug delivery systems particularly in relevance to the antiglaucoma drugs have been discussed. In addition to that, the latest computational/in silico advances in this field are examined in brief. Using nanoscale materials for drug delivery, is...
Thu Sep 24, 2020 15:22
Related Articles Substituted 6,7-dimethoxy-5-oxo-2,3,5,9b-tetrahydrothiazolo[2,3-a]isoindole-3-1,1-dioxidederivatives with antimicrobial activity and docking assisted prediction of the mechanism of their antibacterial and antifungal properties. Curr Top Med Chem. 2020 Sep 22;: Authors: Geronikaki A, Kartsev V, Eleftheriou P, Petrou A, Glamočlija J, Ciric A, Soković M Abstract BACKGROUND: Although, a great number of the targets of antimicrobial...
Thu Sep 24, 2020 15:22
Related Articles Synthesis and biological activity study of tanshinone derivatives: a literature and patent review. Curr Top Med Chem. 2020 Sep 22;: Authors: Huang H, Song C, Chang J Abstract Tanshinones are a class of bioactive compounds present in the Chinese herbal medicine Danshen (Salvia miltiorrhiza Bunge), containing among others abietane diterpene quinone scaffolds. Chemical synthesis and biological activity studies of natural and unnatural...
Thu Sep 24, 2020 15:22
Condition: Recurrent or Metastatic NPCInterventions: Drug: Axitinib; Drug: AvelumabSponsor: Chinese University of Hong KongNot yet recruiting
Thu Sep 24, 2020 15:26
Condition: Differentiated Thyroid CancerIntervention: Device: 99mTC pertechnetate thyroid scanSponsor: Assiut UniversityNot yet recruiting
Thu Sep 24, 2020 15:26
Publication date: Available online 23 September 2020Source: Radiotherapy and OncologyAuthor(s): Matteo Maspero, Laura G Bentvelzen, Mark HF Savenije, Filipa Guerreiro, Enrica Seravalli, Geert O Janssens, Cornelis AT van den Berg, Marielle EP Philippens
Thu Sep 24, 2020 15:27
Publication date: Available online 23 September 2020Source: Radiotherapy and OncologyAuthor(s): Jeho Jeong, Vicki T. Taasti, Andrew Jackson, Joseph O. Deasy
Thu Sep 24, 2020 15:27
Publication date: Available online 23 September 2020Source: Radiotherapy and OncologyAuthor(s): Matthijs H. Valstar, Bernadette S. de Bakker, Roel J.H.M. Steenbakkers, Kees H. de Jong, Laura A. Smit, Thomas J.W. Klein Nulent, Robert J.J. van Es, Ingrid Hofland, Bart de Keizer, Bas Jasperse, Alfons J.M. Balm, Arjen van der Schaaf, Johannes A. Langendijk, Ludi E. Smeele, Wouter V. Vogel
Thu Sep 24, 2020 15:27
Related Articles Ultrasonographic visualisation of anatomical variation of the medial cutaneous nerve of forearm and its depiction by the novel use of a custom computer program to generate 2D diagrams. Reg Anesth Pain Med. 2020 Sep 22;: Authors: Bonshahi A, Biyani G, Sardesai N, Brassett C, Sherman K, Sardesai AM PMID: 32963076 [PubMed - as supplied by publisher]
Thu Sep 24, 2020 15:28
Related Articles Regulation of the KATP-JNK gap junction signaling pathway by immunomodulator astragaloside IV attenuates neuropathic pain. Reg Anesth Pain Med. 2020 Sep 22;: Authors: Dai WL, Zhang L, Han L, Yang X, Hu L, Miao C, Song L, Xiao H, Liu JH, Liu WT Abstract BACKGROUND AND OBJECTIVES: Gap junctions play a pivotal role in contributing to the formation of astroglial networks and in chronic pain. However, the mechanisms underlying...
Thu Sep 24, 2020 15:28
Related Articles Let's talk about sex ̶ placentas' central role in sexually dimorphic responses to the maternal milieu. J Clin Endocrinol Metab. 2020 Sep 23;: Authors: O'Tierney-Ginn P PMID: 32966581 [PubMed - as supplied by publisher]
Thu Sep 24, 2020 15:29
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c07050
Wed Sep 23, 2020 07:00
As the United States navigates the uncertainties of Covid-19 and begins a long-overdue process of confronting systemic racism, the communities most affected by poverty, racism, and language barriers and those with the largest populations of immigrants continue to have the worst health outcomes. In…
Wed Sep 23, 2020 03:00
In late April 2020, Ethan Weiss, a San Francisco cardiologist, joined colleagues in New York to care for critically ill patients with Covid-19. On Weiss’s last day there, a relatively young man was dying of Covid, as his wife lay ill with Covid down the hall. They had been in the hospital nearly a…
Wed Sep 23, 2020 03:00
Presentation of Case. Dr. Jacqueline B. Henson (Medicine): A 54-year-old man was evaluated at this hospital after cardiac arrest associated with ventricular fibrillation. The patient had been in his usual state of health until midday on the day of admission, when he was in a fast-food restaurant…
Thu Sep 24, 2020 03:00
Abstract Radiation monitoring is an important radiation safety measure implemented at the hydrometallurgical plant of the Stepnogorsk mining and chemical combine (HMP SMCC, Republic of Kazakhstan). Follow-up of the workers and their regular medical examinations has laid the basis to create a cohort with the potential to be used in radiation epidemiology. The aim of current pilot study was to analyze the dose forming factors for workers of HMP SMCC. For this, bioassays samples collected...
Thu Sep 24, 2020 03:00
Summary: Dietary supplements are frequently used in surgical patients. Surgeons should be up to date with regard to the efficacies and potential complications related to these supplements. This article provides the most updated practices and evidence of commonly used supplements.
Thu Sep 24, 2020 15:38
No abstract available
Thu Sep 24, 2020 15:38
Background: Physician burnout is a well-known problem and widespread issue in the field of medicine. Recently, more attention has been given to the significance of burnout among plastic surgeons. The cause of burnout is multifactorial, with emotional exhaustion, depersonalization, and a reduced sense of personal accomplishment all playing a role. The objective of this article is to provide practical measures to help plastic surgeons in identifying the signs of burnout, thereby mitigating its consequences. ...
Thu Sep 24, 2020 15:38
No abstract available
Thu Sep 24, 2020 15:38
Background: Even before seeing a physician, patients must first gain access to the hospital system. At large hospitals with high patient volumes, access to specialty care can pose a particular challenge. This study examines the effects of specific initiatives to increase clinic capacity, appointment use, and ease of scheduling on both patient satisfaction and hospital revenue. Methods: In 2017, a task force at a large, multidisciplinary pediatric hospital instituted a number of initiatives...
Thu Sep 24, 2020 15:38
No abstract available
Thu Sep 24, 2020 15:38
Summary: The practice of plastic surgery has become more complex. As plastic surgeons face the postgraduate realities of contracts, negotiations, and health system employment, they are frequently unprepared to effectively manage these challenges. Furthermore, many plastic surgery training programs do not emphasize real-world business and policy concerns in residency training. Plastic and Reconstructive Surgery endeavors to provide robust conceptual education and guidance in business and policy...
Thu Sep 24, 2020 15:38
No abstract available
Thu Sep 24, 2020 15:38
Learning Objectives: After studying this article, participants should be able to: (1) Identify the most appropriate type of anesthesia for the female genital plastic surgical patient and minimize risks of nerve injury and thromboembolic event through proper preoperative evaluation and knowledge of positioning. (2) Define the vulvovaginal anatomy, including common variants, and assess vulvovaginal tissues after childbirth and menopause. (3) Apply surgical techniques to minimize complications in...
Thu Sep 24, 2020 15:38
No abstract available
Thu Sep 24, 2020 15:38
Background: The utility of dermal regeneration templates for treating high-risk diabetic foot wounds is unclear. The authors report wound healing and major amputation outcomes among a cohort of diabetic patients with complex diabetic foot wounds treated in a multidisciplinary setting. Methods: All patients with complex diabetic foot wounds treated with a dermal regeneration template (March of 2013 to February of 2019) were captured in a prospective institutional database. Wound severity was...
Thu Sep 24, 2020 15:38
No abstract available
Thu Sep 24, 2020 15:38
No abstract available
Thu Sep 24, 2020 15:38
No abstract available
Thu Sep 24, 2020 15:38
Background: In open retromuscular ventral hernia repair, fixation-free mesh placement is increasingly prevalent and may minimize pain; the main concern with this technique is short-term technical failure and hernia recurrence. This study compared outcomes following mechanical mesh fixation (i.e., sutures, staples, tacks) versus fixation-free mesh placement. Methods: Adults who underwent open, elective, retromuscular ventral hernia repair of 15 cm width or less with permanent synthetic mesh...
Thu Sep 24, 2020 15:38
No abstract available
Thu Sep 24, 2020 15:38
Summary: The lateral forearm flap—a thin, fasciocutaneous flap harvested over the lateral epicondyle based on the terminal anterior branch of the posterior radial collateral artery—is an attractive alternative to the radial forearm flap. The authors hypothesized that it is safe and effective for head and neck reconstruction. They conducted a retrospective review of all lateral forearm flap reconstructions performed between 2016 and 2018. Patient demographics, defect characteristics, adjuvant therapies,...
Thu Sep 24, 2020 15:38
No abstract available
Thu Sep 24, 2020 15:38
No abstract available
Thu Sep 24, 2020 15:38
No abstract available
Thu Sep 24, 2020 15:38
Background: Virtual surgical planning has contributed to technical advancements in free fibula flap mandible reconstruction. The authors present the largest comparative study on the latest modification of this technology: the use of patient-specific, preoperatively customized reconstruction plates for fixation. Methods: A retrospective chart review was performed on all patients undergoing mandibular reconstruction with virtually planned free fibula flaps at a single institution between 2008...
Thu Sep 24, 2020 15:38
No abstract available
Thu Sep 24, 2020 15:38
Background: Patient selection for headache surgery is an important variable to ensure successful outcomes. In the authors’ experience, a valuable method to visualize pain/trigger sites is to ask patients to draw their pain. The authors have found that there are pathognomonic pain patterns for each site, and typically do not operate on patients with atypical pain sketches, as they believe such patients are poor surgical candidates. However, a small subset of these atypical patients undergo surgery...
Thu Sep 24, 2020 15:38
No abstract available
Thu Sep 24, 2020 15:38
Summary: The purpose of this study was to delineate optimal age to perform unilateral or bilateral cleft lip repair in premature patients. The American College of Surgeons National Surgical Quality Improvement Program Pediatric data set was queried for unilateral and bilateral cleft lip repairs performed between 2012 and 2017. Complications, readmissions, and reoperations were analyzed in the context of prematurity with appropriate statistics. Degree of prematurity was significantly associated...
Thu Sep 24, 2020 15:38
No abstract available
Thu Sep 24, 2020 15:38
Background: No consensus exists about the safest position for performing the osseous genioplasty, with 5 to 6 mm below the mental foramen being the most frequently recommended position. This study intends to generate a safe distance guide to minimize the risk of inferior alveolar nerve injury during osteotomy. Methods: Pretreatment cone-beam computed tomography–derived three-dimensional models from adult patients with skeletal class I to III patterns and cleft lip/palate deformity who underwent...
Thu Sep 24, 2020 15:38
No abstract available
Thu Sep 24, 2020 15:38
Background: Facial asymmetry caused by unilateral condylar hyperplasia requires treatment to address facial and occlusal imbalances. There is no definitive evidence to suggest that a single intervention strategy (during either active condylar overgrowth or the burnt-out phase) results in better/more symmetric correction. This study sought to quantify preoperative and postoperative facial asymmetry in unilateral condylar hyperplasia patients comparing treatment for active versus burnt-out disease. ...
Thu Sep 24, 2020 15:38
No abstract available
Thu Sep 24, 2020 15:38
No abstract available
Thu Sep 24, 2020 15:38
No abstract available
Thu Sep 24, 2020 15:38
Background: Spring-assisted surgery is an accepted alternative to cranial vault remodeling for treatment of sagittal craniosynostosis. The long-term safety and efficacy profiles of spring-assisted surgery have not been established. Methods: This study is a retrospective examination of all patients treated with spring-assisted surgery (n = 175) or cranial vault remodeling (n = 50) for sagittal craniosynostosis at the authors’ institution from 2003 to 2017. Data collected included demographic...
Thu Sep 24, 2020 15:38
No abstract available
Thu Sep 24, 2020 15:38
Background: Although hand surgery is generally safe and effective, some patients experience complications or poor outcomes prompting them to seek compensation. This study reviews malpractice claims in hand surgery using a national data set to assess reasons for litigation and identify predictors of outcome. Methods: The Westlaw database was queried for cases related to hand surgery and medical malpractice between 1989 and 2018. Jury verdicts and settlements were reviewed for relevance, and...
Thu Sep 24, 2020 15:38
Background: In deep inferior epigastric perforator (DIEP) flap breast reconstruction, many surgeons use preoperative imaging for perforator mapping as a method to plan the operation, reduce operative times, and potentially limit morbidity. This study compared operative times for specific portions of DIEP flap harvest with and without preoperative computed tomographic angiography imaging. Methods: Two patient groups undergoing DIEP flap breast reconstruction were studied prospectively. In...
Thu Sep 24, 2020 15:38
No abstract available
Thu Sep 24, 2020 15:38
No abstract available
Thu Sep 24, 2020 15:38
Background: The purpose of this study was to investigate the impact of diabetes on complications after open trigger finger release compared with a cohort matched for age, sex, race, and body mass index class. Methods: A retrospective chart review was performed of diabetic patients who underwent trigger finger release at an academic institution within the past 10 years. Exclusion criteria included rheumatoid arthritis, malignancy, human immunodeficiency virus/acquired immunodeficiency syndrome,...
Thu Sep 24, 2020 15:38
No abstract available
Thu Sep 24, 2020 15:38
Background: Multilevel dysvascular injury of the hand can be treated with replantation or revision amputation. The authors compared both modalities regarding functional outcomes, patient-reported outcomes, and required resources, as relevant studies are scarce. Methods: In this retrospective review of consecutive case series (replantation, n = 8; revision amputation, n = 11), clinical results and functional outcomes (including grip strength, range of motion, sensory recovery, and grip or...
Thu Sep 24, 2020 15:38
No abstract available
Thu Sep 24, 2020 15:38
Background: The supercharge end-to-side anterior interosseous nerve–to–ulnar motor nerve transfer offers a viable option to enhance recovery of intrinsic function following ulnar nerve injury. However, in the setting of chronic ulnar nerve compression where the timing of onset of axonal loss is unclear, there is a deficit in the literature on outcomes after supercharge end-to-side anterior interosseous nerve–to–ulnar motor nerve transfer. Methods: A retrospective study of patients who underwent...
Thu Sep 24, 2020 15:38
No abstract available
Thu Sep 24, 2020 15:38
Background: Dupuytren’s disease is a common complex disease caused by genetic and nongenetic factors. The role of many nongenetic risk factors is still unclear and debatable. This study aimed to systematically review the association between Dupuytren’s disease and nongenetic risk factors. Methods: A search strategy was developed based on the Population, Exposure, Comparison, Outcomes and Study framework. A Preferred Reporting Items for Systematic Reviews and Meta-Analyses–compliant literature...
Thu Sep 24, 2020 15:38
No abstract available
Thu Sep 24, 2020 15:38
Background: Tissue expansion relies on the ability of skin to grow in response to sustained mechanical strain. This study focuses on correlation of cellular and histologic changes with skin growth and deformation during tissue expansion. Methods: Tissue expanders were placed underneath the skin of five Yucatan minipigs and inflated with one fill of 60 cc of saline 1 hour, 24 hours, 3 days, and 7 days before the animals were killed, or two fills of either 30 cc or 60 cc at 10 and 3 days or...
Thu Sep 24, 2020 15:38
No abstract available
Thu Sep 24, 2020 15:38
Background: The traditional method of distraction required a long period until the new bone was fully fused. This study aimed to evaluate the effect of cyclic and repetitive compressive force on new bone formation by applying a newly designed microactuator-generated distractor compared with the traditional distraction protocol. Methods: The distraction devices were applied to the right and left mandibles of eight mature beagles, four of which were allocated to the experimental group and the...
Thu Sep 24, 2020 15:38
No abstract available
Thu Sep 24, 2020 15:38
Summary: Volume restoration with autologous fat augmentation has become a key technique in facial rejuvenation. It is highly versatile and useful as an independent operation or as an adjunct to rhytidectomy and blepharoplasty. The goal of this article and the accompanying videos is to provide a detailed step-by-step guide to achieving predictable and optimized surgical results.
Thu Sep 24, 2020 15:38
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