Παρασκευή 25 Σεπτεμβρίου 2020

 

The protective effect and mechanism of pedunculoside on DSS (dextran sulfate sodium) induced ulcerative colitis in mice
Publication date: November 2020Source: International Immunopharmacology, Volume 88Author(s): Kunjian Liu, Guofeng Li, Wenjin Guo, Jiao Zhang
ScienceDirect Publication: International Immunopharmacology
Thu Sep 24, 2020 19:46
Sesamin attenuates carrageenan-induced lung inflammation through upregulation of A20 and TAX1BP1 in rats
Publication date: November 2020Source: International Immunopharmacology, Volume 88Author(s): He Ye, Liyan Sun, Jun Li, Yayun Wang, Junzhe Bai, Liang Wu, Qi Han, Zhiping Yang, Li Li
ScienceDirect Publication: International Immunopharmacology
Thu Sep 24, 2020 19:46
Clinical and radiological outcomes of single-level cervical disc arthroplasty in the patients with preoperative reversible kyphosis: A matched cohort study
Publication date: Available online 23 September 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Hu Xu, Hao Liu, Ying Hong, Xin Rong, Kangkang Huang, Pu Dan, Beiyu Wang
Clinical Neurology and Neurosurgery
Thu Sep 24, 2020 19:48
Therapeutic interventions for Pisa syndrome in idiopathic Parkinson's disease. A Scoping Systematic Review
Publication date: November 2020Source: Clinical Neurology and Neurosurgery, Volume 198Author(s): Mohammad Etoom, Mohammad Alwardat, Ala’ S. Aburub, Francesco Lena, Roberto Fabbrizo, Nicola Modugno, Diego Centonze
Clinical Neurology and Neurosurgery
Thu Sep 24, 2020 19:48
Transradial access for thrombectomy in acute stroke: A systematic review and meta-analysis
Publication date: November 2020Source: Clinical Neurology and Neurosurgery, Volume 198Author(s): Catherine Peterson, Ben Waldau
Clinical Neurology and Neurosurgery
Thu Sep 24, 2020 19:48
Online Hearing Tests Do Not Encourage Patients to Adopt Hearing Aids
​Despite booming consumer interest in online hearing testing, none of the leading tests consistently use best practices to encourage patients to pursue treatment with hearing aids, according to new research from Auditory Insight. In a study examining the online hearing tests from eight leading direct-to-consumer hearing aid brands, including Audicus, Eargo, and MDHearingAid, as well as those from eight leading brands retailed through audiologists, including Phonak, GN Resound, and Starkey, Auditory...
Audiology
Wed Sep 23, 2020 14:45
New Ponto Care™ App for Bone-Anchored Hearing Device Users Now Supports Aftercare
Oticon Medical has launched the Ponto Care™ app, a supportive and easy-to-use mobile application for all bone-anchored hearing device users. It expands on the previously released Ponto Trial Companion app by adding a second section, Aftercare.The goal of creating the Ponto Care app was to support users becoming more engaged, independent, and involved in their bone anchored hearing treatment. The app provides them with the self-help tools needed for more insightful conversations with their hearing...
Audiology
Wed Sep 23, 2020 18:53
The progression of metastatic melanoma augments a pro-oxidative milieu locally but not systemically
Publication date: Available online 23 September 2020Source: Pathology - Research and PracticeAuthor(s): Gabriella Pasqual-Melo, Sara S. Bernardes, Fernando P. Souza-Neto, Iriana M. Carrara, Leandra N.Z. Ramalho, Poliana C. Marinello, Rodrigo C. Luiz, Rubens Cecchini, Sander Bekeschus, Alessandra L. Cecchini
ScienceDirect Publication: Pathology - Research and Practice
Thu Sep 24, 2020 20:01
Management of complicated pediatric rhinosinusitis in the COVID-19 era
Publication date: Available online 23 September 2020Source: American Journal of OtolaryngologyAuthor(s): Conor H. Blanco, John B. Stein, Gregory L. Barinsky, Christina H. Fang, Jordon G. Grube, Roger E. Turbin, Jean Anderson Eloy
American Journal of Otolaryngology
Thu Sep 24, 2020 20:04
Reply to: Correspondence ‐ Association of spontaneous cerebrospinal fluid rhinorrhea with transverse venous sinus stenosis: a retrospective matched case‐control study
International Forum of Allergy & Rhinology
Thu Sep 24, 2020 18:13
Efficacy of the exhalation delivery system with fluticasone in patients who remain symptomatic on standard nasal steroid sprays
Background Standard nasal steroid sprays are often first‐line treatment for chronic rhinosinusitis (CRS), but many patients remain symptomatic despite their use. The exhalation delivery system with fluticasone (EDS‐FLU) has been shown to be efficacious in mixed populations of symptomatic patients, but the question remains whether benefits would be similar in those already on traditional steroid sprays. The goal of this study was to compare EDS‐FLU treatment outcomes in patients who have previously...
International Forum of Allergy & Rhinology
Thu Sep 24, 2020 18:15
Retraction notice to: “Correlation of clinicopathological features and LGR5 expression in colon adenocarcinoma” [Annals of Diagnostic Pathology 40C (2020) 161–165]
Publication date: October 2020Source: Annals of Diagnostic Pathology, Volume 48Author(s): Koichi Sato, Takeshi Uehara, Mai Iwaya, Tomoyuki Nakajima, Yusuke Miyagawa, Tomoaki Suga, Hiroyoshi Ota, Eiji Tanaka
Annals of Diagnostic Pathology
Thu Sep 24, 2020 20:17
ExActa HIF prolyl hydroxylase inhibitors-The new lifestyle drug?
Related Articles ExActa HIF prolyl hydroxylase inhibitors-The new lifestyle drug? Acta Physiol (Oxf). 2019 11;227(3):e13370 Authors: Sciesielski LK, Kirschner KM PMID: 31465609 [PubMed - indexed for MEDLINE]
Hypoxia-inducible factors
Thu Sep 24, 2020 20:29
"Oncol Lett"[jour]; +26 new citations
26 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Oncol Lett"[jour] These pubmed results were generated on 2020/09/24PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Oncology Letters
Thu Sep 24, 2020 20:44
Combined web and haptic simulation system: A pilot study
Publication date: November 2020Source: International Journal of Pediatric Otorhinolaryngology, Volume 138Author(s): Tulio A. Valdez, Sahith Kudaravalli, Katherine R. Kavanagh
Pediatric Otorhinolaryngology
Thu Sep 24, 2020 20:46
Investigation of DFNB4 SLC26A4 mutation in patients with enlarged vestibular aquaduct
Publication date: November 2020Source: International Journal of Pediatric Otorhinolaryngology, Volume 138Author(s): Kubilay Kınoğlu, Kadir Serkan Orhan, Hakan Kara, Oğuz Öztürk, Beldan Polat, Hülya Aydoğan, Mehmet Çelik, Ayşe Begüm Ceviz, Yahya Güldiken
Pediatric Otorhinolaryngology
Thu Sep 24, 2020 20:46
Utilizing immediate preoperative n-BCA in the resection of head and neck venous and lymphatic malformations
Publication date: November 2020Source: International Journal of Pediatric Otorhinolaryngology, Volume 138Author(s): Ryan Puccia, Kelly Staricha, Valerie M. Carlberg, David Moe, Robert Chun
Pediatric Otorhinolaryngology
Thu Sep 24, 2020 20:46
Newborn hearing screening results: Comparison of Syrian and Turkish newborns; factors influencing the difference
Publication date: November 2020Source: International Journal of Pediatric Otorhinolaryngology, Volume 138Author(s): Mehmet Erkan Kaplama, Ahmet Yukkaldiran, Semih Ak
Pediatric Otorhinolaryngology
Thu Sep 24, 2020 20:46
Outer hair cell functioning in infants with iron deficiency anemia
Publication date: November 2020Source: International Journal of Pediatric Otorhinolaryngology, Volume 138Author(s): Hemawathiy Sundagumaran, Jayashree Seethapathy
Pediatric Otorhinolaryngology
Thu Sep 24, 2020 20:46
Effects of small interfering RNA-mediated silencing of susceptibility genes of non-syndromic cleft lip with or without cleft palate on cell proliferation and migration
Publication date: November 2020Source: International Journal of Pediatric Otorhinolaryngology, Volume 138Author(s): Meng-Xue Li, Zheng Li, Rui Zhang, Yue Yu, Lu-Shan Wang, Qi Wang, Zhen Ding, Jin-Peng Zhang, Mei-Rong Zhang, Li-Chun Xu
Pediatric Otorhinolaryngology
Thu Sep 24, 2020 20:46
Postoperative pain course after paediatric tonsillectomy: A prospective observational study comparing one behavioural and one numerical pain assessment tool
Publication date: November 2020Source: International Journal of Pediatric Otorhinolaryngology, Volume 138Author(s): David Hui, Signe Søvik
Pediatric Otorhinolaryngology
Thu Sep 24, 2020 20:46
A Farewell Gift from My Mother
After performing my beachside neurologic exam, complete with lobster hammer to check reflexes, I made a mistake I would never have made with a patient. "Mom," I said, "There are some subtle findings. You need an MRI, but don’t worry — it’s not like you have a brain tumor." I advised my mother to…
The New England Journal of Medicine: Search Results in Hematology\Oncology
Thu Sep 24, 2020 03:00
Case 30-2020: A 54-Year-Old Man with Sudden Cardiac Arrest
Presentation of Case. Dr. Jacqueline B. Henson (Medicine): A 54-year-old man was evaluated at this hospital after cardiac arrest associated with ventricular fibrillation. The patient had been in his usual state of health until midday on the day of admission, when he was in a fast-food restaurant…
Clinical Cases
Thu Sep 24, 2020 03:00
The endoplasmic reticulum P5A-ATPase is a transmembrane helix dislocase
Organelle identity depends on protein composition. How mistargeted proteins are selectively recognized and removed from organelles is incompletely understood. Here, we found that the orphan P5A–adenosine triphosphatase (ATPase) transporter ATP13A1 (Spf1 in yeast) directly interacted with the transmembrane segment (TM) of mitochondrial tail–anchored proteins. P5A-ATPase activity mediated the extraction of mistargeted proteins from the endoplasmic reticulum (ER). Cryo–electron microscopy structures...
Science: Current Issue
Thu Sep 24, 2020 20:40
Nonlinear x-ray spectroscopy
Science: Current Issue
Thu Sep 24, 2020 20:40
The science and medicine of human immunology
Although the development of effective vaccines has saved countless lives from infectious diseases, the basic workings of the human immune system are complex and have required the development of animal models, such as inbred mice, to define mechanisms of immunity. More recently, new strategies and technologies have been developed to directly explore the human immune system with unprecedented precision. We discuss how these approaches are advancing our mechanistic understanding of human immunology...
Science: Current Issue
Thu Sep 24, 2020 20:40
Basic principles of bird and mammal brains
Science: Current Issue
Thu Sep 24, 2020 20:40
Full disclosure
Science: Current Issue
Thu Sep 24, 2020 20:40
Mapping primordial reaction networks
Science: Current Issue
Thu Sep 24, 2020 20:40
Large-scale RNAi screening uncovers therapeutic targets in the parasite Schistosoma mansoni
Schistosome parasites kill 250,000 people every year. Treatment of schistosomiasis relies on the drug praziquantel. Unfortunately, a scarcity of molecular tools has hindered the discovery of new drug targets. Here, we describe a large-scale RNA interference (RNAi) screen in adult Schistosoma mansoni that examined the function of 2216 genes. We identified 261 genes with phenotypes affecting neuromuscular function, tissue integrity, stem cell maintenance, and parasite survival. Leveraging these data,...
Science: Current Issue
Thu Sep 24, 2020 20:40
Dissecting membrane dislocation
Science: Current Issue
Thu Sep 24, 2020 20:40
Designed protein logic to target cells with precise combinations of surface antigens
Precise cell targeting is challenging because most mammalian cell types lack a single surface marker that distinguishes them from other cells. A solution would be to target cells using specific combinations of proteins present on their surfaces. In this study, we design colocalization-dependent protein switches (Co-LOCKR) that perform AND, OR, and NOT Boolean logic operations. These switches activate through a conformational change only when all conditions are met, generating rapid, transcription-independent...
Science: Current Issue
Thu Sep 24, 2020 20:40
Immunology through a human lens
Science: Current Issue
Thu Sep 24, 2020 20:40
Photon-recoil imaging: Expanding the view of nonlinear x-ray physics
Addressing the ultrafast coherent evolution of electronic wave functions has long been a goal of nonlinear x-ray physics. A first step toward this goal is the investigation of stimulated x-ray Raman scattering (SXRS) using intense pulses from an x-ray free-electron laser. Earlier SXRS experiments relied on signal amplification during pulse propagation through dense resonant media. By contrast, our method reveals the fundamental process in which photons from the primary radiation source directly interact...
Science: Current Issue
Thu Sep 24, 2020 20:40
Antarctic ice sheet melting and climate
Science: Current Issue
Thu Sep 24, 2020 20:40
High-impact marine heatwaves attributable to human-induced global warming
Marine heatwaves (MHWs)—periods of extremely high ocean temperatures in specific regions—have occurred in all of Earth’s ocean basins over the past two decades, with severe negative impacts on marine organisms and ecosystems. However, for most individual MHWs, it is unclear to what extent they have been altered by human-induced climate change. We show that the occurrence probabilities of the duration, intensity, and cumulative intensity of most documented, large, and impactful MHWs have increased...
Science: Current Issue
Thu Sep 24, 2020 20:40
Tipsy microglia binge on synapses
Science: Current Issue
Thu Sep 24, 2020 20:40
The immunogenetics of sexual parasitism
Sexual parasitism has evolved as a distinctive mode of reproduction among deep-sea anglerfishes. The permanent attachment of males to host females observed in these species represents a form of anatomical joining, which is otherwise unknown in nature. Pronounced modifications to immune facilities are associated with this reproductive trait. The genomes of species with temporarily attaching males lack functional aicda genes that underpin affinity maturation of antibodies. Permanent attachment is associated...
Science: Current Issue
Thu Sep 24, 2020 20:40
Duality of roaming mechanism in H2CO
Science: Current Issue
Thu Sep 24, 2020 20:40
Inducing metallicity in graphene nanoribbons via zero-mode superlattices
The design and fabrication of robust metallic states in graphene nanoribbons (GNRs) are challenging because lateral quantum confinement and many-electron interactions induce electronic band gaps when graphene is patterned at nanometer length scales. Recent developments in bottom-up synthesis have enabled the design and characterization of atomically precise GNRs, but strategies for realizing GNR metallicity have been elusive. Here we demonstrate a general technique for inducing metallicity in GNRs...
Science: Current Issue
Thu Sep 24, 2020 20:40
Making metallic ribbons
Science: Current Issue
Thu Sep 24, 2020 20:40
Distinct conformational states of SARS-CoV-2 spike protein
Intervention strategies are urgently needed to control the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. The trimeric viral spike (S) protein catalyzes fusion between viral and target cell membranes to initiate infection. Here, we report two cryo–electron microscopy structures derived from a preparation of the full-length S protein, representing its prefusion (2.9-angstrom resolution) and postfusion (3.0-angstrom resolution) conformations, respectively. The spontaneous transition...
Science: Current Issue
Thu Sep 24, 2020 20:40
Modeling SARS-CoV-2 in mice
Science: Current Issue
Thu Sep 24, 2020 20:40
Merging across the black hole mass gap
Science: Current Issue
Thu Sep 24, 2020 20:40
A dynamic viral spike
Science: Current Issue
Thu Sep 24, 2020 20:40
Carotenoids drive chromoplast development
Science: Current Issue
Thu Sep 24, 2020 20:40
Logic at the cell surface
Science: Current Issue
Thu Sep 24, 2020 20:40
A bacterial battleground
Science: Current Issue
Thu Sep 24, 2020 20:40
Reconfiguring an immune response
Science: Current Issue
Thu Sep 24, 2020 20:40
Cerebrospinal fluid snapshot
Science: Current Issue
Thu Sep 24, 2020 20:40
Internet voting remains insecure, says AAAS EPI Center
Science: Current Issue
Thu Sep 24, 2020 20:40
Schistosome biology illuminated
Science: Current Issue
Thu Sep 24, 2020 20:40
Swiss law would weaken wildlife protection
Science: Current Issue
Thu Sep 24, 2020 20:40
Y chromosome evolution in Neanderthals
Science: Current Issue
Thu Sep 24, 2020 20:40
Traditional Knowledge underlies One Health
Science: Current Issue
Thu Sep 24, 2020 20:40
Fumarate targets pyroptosis
Science: Current Issue
Thu Sep 24, 2020 20:40
India needs an effective flood policy
Science: Current Issue
Thu Sep 24, 2020 20:40
Operating in wet conditions
Science: Current Issue
Thu Sep 24, 2020 20:40
The race to decipher Egyptian hieroglyphs
Science: Current Issue
Thu Sep 24, 2020 20:40
A cortex-like canonical circuit in the avian forebrain
Although the avian pallium seems to lack an organization akin to that of the cerebral cortex, birds exhibit extraordinary cognitive skills that are comparable to those of mammals. We analyzed the fiber architecture of the avian pallium with three-dimensional polarized light imaging and subsequently reconstructed local and associative pallial circuits with tracing techniques. We discovered an iteratively repeated, column-like neuronal circuitry across the layer-like nuclear boundaries of the hyperpallium...
Science: Current Issue
Thu Sep 24, 2020 20:40
Understanding quantum cause and effect
Science: Current Issue
Thu Sep 24, 2020 20:40
The evolutionary history of Neanderthal and Denisovan Y chromosomes
Ancient DNA has provided new insights into many aspects of human history. However, we lack comprehensive studies of the Y chromosomes of Denisovans and Neanderthals because the majority of specimens that have been sequenced to sufficient coverage are female. Sequencing Y chromosomes from two Denisovans and three Neanderthals shows that the Y chromosomes of Denisovans split around 700 thousand years ago from a lineage shared by Neanderthals and modern human Y chromosomes, which diverged from each...
Science: Current Issue
Thu Sep 24, 2020 20:40
Self-experimentation, ethics, and regulation of vaccines
Science: Current Issue
Thu Sep 24, 2020 20:40
Succination inactivates gasdermin D and blocks pyroptosis
Activated macrophages undergo a metabolic switch to aerobic glycolysis, accumulating Krebs’ cycle intermediates that alter transcription of immune response genes. We extended these observations by defining fumarate as an inhibitor of pyroptotic cell death. We found that dimethyl fumarate (DMF) delivered to cells or endogenous fumarate reacts with gasdermin D (GSDMD) at critical cysteine residues to form S-(2-succinyl)-cysteine. GSDMD succination prevents its interaction with caspases, limiting its...
Science: Current Issue
Thu Sep 24, 2020 20:40
Intense x-rays can be (slightly) exciting
Science: Current Issue
Thu Sep 24, 2020 20:40
Stable perovskite solar cells with efficiency exceeding 24.8% and 0.3-V voltage loss
Further improvement and stabilization of perovskite solar cell (PSC) performance are essential to achieve the commercial viability of next-generation photovoltaics. Considering the benefits of fluorination to conjugated materials for energy levels, hydrophobicity, and noncovalent interactions, two fluorinated isomeric analogs of the well-known hole-transporting material (HTM) Spiro-OMeTAD are developed and used as HTMs in PSCs. The structure–property relationship induced by constitutional isomerism...
Science: Current Issue
Thu Sep 24, 2020 20:40
Birds do have a brain cortex--and think
Science: Current Issue
Thu Sep 24, 2020 20:40
Rotational resonances in the H2CO roaming reaction are revealed by detailed correlations
Since its discovery 16 years ago, roaming has become a ubiquitous mechanism in molecular photochemistry. Its general features are now understood, but little detail is known about how the potential energy surface (PES) determines reaction outcomes. We performed detailed experiments on formaldehyde (H2CO) photodissociation and determined fully correlated quantum state distributions of the molecular hydrogen and carbon monoxide products. These experiments reveal previously undetected bimodal carbon...
Science: Current Issue
Thu Sep 24, 2020 20:40
The last pieces of a puzzling early meeting
Science: Current Issue
Thu Sep 24, 2020 20:40
Identity by association
Science: Current Issue
Thu Sep 24, 2020 20:40
Preventing pores and inflammation
Science: Current Issue
Thu Sep 24, 2020 20:40
Dogs return to the show
Science: Current Issue
Thu Sep 24, 2020 20:40
Transformative tools for parasitic flatworms
Science: Current Issue
Thu Sep 24, 2020 20:40
Remediating malalignment
Science: Current Issue
Thu Sep 24, 2020 20:40
A tropical research treasure faces difficult times
Science: Current Issue
Thu Sep 24, 2020 20:40
The heat is on
Science: Current Issue
Thu Sep 24, 2020 20:40
Seeking a niche
Science: Current Issue
Thu Sep 24, 2020 20:40
Synthetic connectivity, emergence, and self-regeneration in the network of prebiotic chemistry
The challenge of prebiotic chemistry is to trace the syntheses of life’s key building blocks from a handful of primordial substrates. Here we report a forward-synthesis algorithm that generates a full network of prebiotic chemical reactions accessible from these substrates under generally accepted conditions. This network contains both reported and previously unidentified routes to biotic targets, as well as plausible syntheses of abiotic molecules. It also exhibits three forms of nontrivial chemical...
Science: Current Issue
Thu Sep 24, 2020 20:40
Sizing up a green carbon sink
Science: Current Issue
Thu Sep 24, 2020 20:40
A neural correlate of sensory consciousness in a corvid bird
Subjective experiences that can be consciously accessed and reported are associated with the cerebral cortex. Whether sensory consciousness can also arise from differently organized brains that lack a layered cerebral cortex, such as the bird brain, remains unknown. We show that single-neuron responses in the pallial endbrain of crows performing a visual detection task correlate with the birds’ perception about stimulus presence or absence and argue that this is an empirical marker of avian consciousness....
Science: Current Issue
Thu Sep 24, 2020 20:40
The short, strange life of quantum radar
Science: Current Issue
Thu Sep 24, 2020 20:40
Cyclopropanes through C-H activation
Science: Current Issue
Thu Sep 24, 2020 20:40
Curved scour marks trace the directions of ancient quakes
Science: Current Issue
Thu Sep 24, 2020 20:40
An Olympic curling robot
Science: Current Issue
Thu Sep 24, 2020 20:40
Turkey targets critics of its pandemic response
Science: Current Issue
Thu Sep 24, 2020 20:40
Dark skies and bright satellites
Science: Current Issue
Thu Sep 24, 2020 20:40
Despite obstacles, WHO unveils plan to distribute vaccine
Science: Current Issue
Thu Sep 24, 2020 20:40
Adaptation of SARS-CoV-2 in BALB/c mice for testing vaccine efficacy
The ongoing coronavirus disease 2019 (COVID-19) pandemic has prioritized the development of small-animal models for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We adapted a clinical isolate of SARS-CoV-2 by serial passaging in the respiratory tract of aged BALB/c mice. The resulting mouse-adapted strain at passage 6 (called MASCp6) showed increased infectivity in mouse lung and led to interstitial pneumonia and inflammatory responses in both young and aged mice after intranasal...
Science: Current Issue
Thu Sep 24, 2020 20:40
Fighting to be counted
Science: Current Issue
Thu Sep 24, 2020 20:40
Consciousness shared
Science: Current Issue
Thu Sep 24, 2020 20:40
Flawed interferon response spurs severe illness
Science: Current Issue
Thu Sep 24, 2020 20:40
Identifying the weakest links
Science: Current Issue
Thu Sep 24, 2020 20:40
News at a glance
Science: Current Issue
Thu Sep 24, 2020 20:40
A single-cell RNA-seq atlas of Schistosoma mansoni identifies a key regulator of blood feeding
Schistosomiasis is a neglected tropical disease that infects 240 million people. With no vaccines and only one drug available, new therapeutic targets are needed. The causative agents, schistosomes, are intravascular flatworm parasites that feed on blood and lay eggs, resulting in pathology. The function of the parasite’s various tissues in successful parasitism are poorly understood, hindering identification of therapeutic targets. Using single-cell RNA sequencing (RNA-seq), we characterize 43,642...
Science: Current Issue
Thu Sep 24, 2020 20:40
Feasibility of fecal microbiota transplantation via oral gavage to safely alter gut microbiome composition in marmosets
Mean percent relative abundance changes in marmoset gut miocrobiota Phyla from baseline to 6 months post fecal transplant. Abstract Disruption of microbial communities within human hosts has been associated with infection, obesity, cognitive decline, cancer risk and frailty, suggesting that microbiome‐targeted therapies may be an option for improving healthspan and lifespan. The objectives of this study were to determine the feasibility of delivering fecal microbiota transplants (FMTs) to...
American Journal of Primatology
Thu Sep 24, 2020 19:03
Associations of multimorbidity with breast, cervical, and colorectal cancer screening delivery: a cross-sectional study of a nationally representative Japanese sample
Publication date: December 2020Source: Cancer Epidemiology, Volume 69Author(s): Hiromitsu Yamashita, Yoshimitsu Takahashi, Tatsuro Ishizaki, Haruki Imura, Takeo Nakayama
ScienceDirect Publication: Cancer Epidemiology (open access)
Thu Sep 24, 2020 21:30
Melanoma brain metastases have lower T-cell content and microvessel density compared to matched extracranial metastases
Abstract Background Although melanoma brain metastases (MBM) tend to respond to systemic therapy concordantly with extracranial metastases, little is known about differences in immune cell and vascular content between the brain and other metastatic sites. Here we studied infiltrating immune cell subsets and microvessel density (MVD) in paired intracerebral and extracerebral melanoma metastases. ...
Neuro-Oncology
Thu Sep 24, 2020 03:00
Secretory IgA <i>N</i>-glycans contribute to the protection against <i>E. coli</i> O55 infection of germ-free piglets
Mucosal Immunology, Published online: 24 September 2020; doi:10.1038/s41385-020-00345-8Secretory IgA N-glycans contribute to the protection against E. coli O55 infection of germ-free piglets
Mucosal Immunology - Issue - nature.com science feeds
Thu Sep 24, 2020 03:00
CRISPR/Cas13: A potential therapeutic option of COVID-19
Publication date: November 2020Source: Biomedicine & Pharmacotherapy, Volume 131Author(s): Melika Lotfi, Nima Rezaei
Biomedicine & Pharmacotherapy
Thu Sep 24, 2020 22:57

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