Related Articles The Ibr-7 derivative of ibrutinib radiosensitizes pancreatic cancer cells by downregulating p-EGFR. Cancer Cell Int. 2020;20:458 Authors: Tan B, Dong R, Zhang B, Yan Y, Li Q, Wang F, Lin N Abstract Background: Radiotherapy is one of the main treatments for pancreatic cancer, but radiation resistance limits its clinical application. As a result, novel therapeutic agents to improve radiosensitivity are urgently needed. This...
Related Articles Extract of Pogostemon cablin Possesses Potent Anticancer Activity against Colorectal Cancer Cells In Vitro and In Vivo. Evid Based Complement Alternat Med. 2020;2020:9758156 Authors: Chien JH, Lee SC, Chang KF, Huang XF, Chen YT, Tsai NM Abstract Pogostemon cablin (PCa), an herb used in traditional Chinese medicine, is routinely used in the amelioration of different types of gastrointestinal discomfort. However, the mechanisms...
Related Articles 6,12-Diphenyl-3, 9-diazatetraasterane-1, 5, 7, 11-tetracarboxylate Inhibits Proliferation, Migration and Promotes Apoptosis in Ovarian Cancer Cells. Dis Markers. 2020;2020:5068067 Authors: Chen P, Wang H, Li M, Yang L, Mou F, Singh B, He JY, Zhang W Abstract 6,12-Diphenyl-3,9-diazatetraasterane-1, 5, 7, 11-tetracarboxylate (DDTC) has been synthesized by the photodimerization of 4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate....
Related Articles Rational drug design, synthesis, and biological evaluation of novel chiral tetrahydronaphthalene-fused spirooxindole as MDM2-CDK4 dual inhibitor against glioblastoma. Acta Pharm Sin B. 2020 Aug;10(8):1492-1510 Authors: Wang B, Peng F, Huang W, Zhou J, Zhang N, Sheng J, Haruehanroengra P, He G, Han B Abstract Simultaneous inhibition of MDM2 and CDK4 may be an effective treatment against glioblastoma. A collection of chiral...
Related Articles Inhibitory activity of flaxseed oil against CdCl2 induced liver and kidney damage: Histopathology, genotoxicity, and gene expression study. Toxicol Rep. 2020;7:1127-1137 Authors: Diab KA, Ibrahim NE, Fahmy MA, Hassan EM, Omara EA Abstract The present work evaluated the effect of flaxseed oil (FO) against toxicity induced by cadmium chloride (CdCl2) in the mouse liver and kidney. Male Swiss albino mice were treated with...
Related Articles MicroRNA-587 Functions as a Tumor Suppressor in Hepatocellular Carcinoma by Targeting Ribosomal Protein SA. Biomed Res Int. 2020;2020:3280530 Authors: Chen M, Wang D, Liu J, Zhou Z, Ding Z, Liu L, Su D, Li H Abstract Background: Hepatocellular carcinoma (HCC) is one of the most highly aggressive cancer worldwide with an extremely poor prognosis. Evidence has revealed that microRNA-587 (miR-587) is abnormally expressed in...
Related Articles FKBP51 acts as a biomarker of early metastasis and is related to carmustine sensitivity in human glioma cells. Eur Rev Med Pharmacol Sci. 2020 Sep;24(17):8918-8930 Authors: Li H, Jiao YL, Zhou RF, Liu S, Cui B, Wang LC, Liu XW, Zhao YR Abstract OBJECTIVE: Given that FK506 binding protein 51 (FKBP51) is upregulated in multiple cancers, we designed the present study to characterize its role as well as underlying regulatory...
Related Articles Growth disadvantage associated with centrosome amplification drives population-level centriole number homeostasis. Mol Biol Cell. 2020 Sep 23;:mbcE19040195 Authors: Sala R, Farrell KC, Stearns T Abstract The centriole duplication cycle normally ensures that centriole number is maintained at two centrioles per G1 cell. However, some circumstances can result in an aberrant increase in centriole number-a phenotype that is...
Related Articles Inhibition of p97/VCP function leads to defective autophagosome maturation, cell cycle arrest and apoptosis in mouse Sertoli cells. Theriogenology. 2020 Sep 15;158:196-206 Authors: Cayli S, Sahin C, Sanci TO, Nakkas H Abstract p97/valosin-containing protein (VCP) is expressed in many cells and plays critical functions in a broad range of diverse cellular processes. Because it is expressed in the mouse testes, predominantly...
Related Articles HDAC3 Silencing Enhances Acute B Lymphoblastic Leukaemia Cells Sensitivity to MG-132 by Inhibiting the JAK/Signal Transducer and Activator of Transcription 3 Signaling Pathway. Chemotherapy. 2020 Sep 23;:1-16 Authors: Guo Y, Li X, He Z, Ma D, Zhang Z, Wang W, Xiong J, Kuang X, Wang J Abstract PURPOSE: HDAC3, which is associated with smurf2, has been shown to be associated with poor prognosis in B-ALL. This study examined...
Related Articles piRNA-30473 contributes to tumorigenesis and poor prognosis by regulating m6A RNA methylation in DLBCL. Blood. 2020 Sep 23;: Authors: Han H, Fan G, Song S, Jiang Y, Qian C, Zhang W, Su Q, Xue X, Zhuang W, Li B Abstract The initiation and progression of diffuse large B-cell lymphoma (DLBCL) is governed by genetic and epigenetic aberrations. As the most abundant eukaryotic message RNA modification, N6-methyladenosine (m6A)...
After performing my beachside neurologic exam, complete with lobster hammer to check reflexes, I made a mistake I would never have made with a patient. "Mom," I said, "There are some subtle findings. You need an MRI, but don’t worry — it’s not like you have a brain tumor." I advised my mother to…
Major loss of muscle protein (atrophy, or wasting) is commonly seen in old age (sarcopenia), in cases of muscle disuse or denervation, and in systemic inflammatory catabolic states. Loss of skeletal muscle mass and function has mental, social, and physical health consequences that diminish quality…
Abstract Background The periodontal healing distal to the mandibular second molar (M2M) after coronectomy of the M3M has shown controversial results. We aimed to combine a digital method with cone-beam computed tomography (CBCT) and estimate periodontal healing of M2M after M3M coronectomy. An accurate and stable indicator in three dimensions was also explored tentatively. ...
Abstract Myelin is a key component of the peripheral nervous system (PNS), whose structure anomaly in the digital skin is implicated in neuropathy. Here we demonstrate an in vivo labeling and imaging technique, capable of visualizing myelin sheaths deep in the mouse digital skin. Through material characterization, we verify that 3‐photon fluorescence (3PF) can be generated from a commonly used dye‐ FluoroMyelin Red for labeling myelin, excited at the 1700‐nm window. Topical injection of FluoroMyelin...
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Related Articles Adjuvant Chemotherapy for Stage III Colon Cancer. Cancers (Basel). 2020 Sep 19;12(9): Authors: Taieb J, Gallois C Abstract In patients with stage III colon cancer (CC), adjuvant chemotherapy with the combination of oxapliplatin to a fluoropyrimidine (FOLFOX or CAPOX) is a standard of care. The duration of treatment can be reduced from 6 months to 3 months, depending on the regimen, for patients at low risk of recurrence, without...
Related Articles Targeting Molecular Mechanisms Underlying Treatment Efficacy and Resistance in Osteosarcoma: A Review of Current and Future Strategies. Int J Mol Sci. 2020 Sep 19;21(18): Authors: Lilienthal I, Herold N Abstract Osteosarcoma is the most common primary malignant bone tumour in children and adolescents. Due to micrometastatic spread, radical surgery alone rarely results in cure. Introduction of combination chemotherapy in the...
Related Articles A data-driven approach to a chemotherapy recommendation model based on deep learning for patients with colorectal cancer in Korea. BMC Med Inform Decis Mak. 2020 Sep 22;20(1):241 Authors: Park JH, Baek JH, Sym SJ, Lee KY, Lee Y Abstract BACKGROUND: Clinical Decision Support Systems (CDSSs) have recently attracted attention as a method for minimizing medical errors. Existing CDSSs are limited in that they do not reflect actual...
Related Articles Cost-effectiveness of treating head and neck cancer using intensity-modulated radiation therapy: implications for cancer control program in India. Int J Technol Assess Health Care. 2020 Sep 23;:1-8 Authors: Chauhan AS, Prinja S, Ghoshal S, Verma R Abstract BACKGROUND: The newer cancer treatment technologies hold the potential of providing improved health outcomes at an additional cost. So it becomes obligatory to assess the...
Related Articles Clinical case of the neoadjuvant treatment with nivolumab in a patient with microsatellite unstable (MSI-H) locally advanced gastric cancer. BMJ Case Rep. 2020 Sep 22;13(9): Authors: Chubenko V, Inusilaev G, Imyanitov E, Moiseyenko V Abstract Locally advanced gastric cancer (GC) is often managed by neoadjuvant chemotherapy and surgery; however, pathological complete responses to preoperative systemic treatment are rare. Some...
Related Articles Examination of potential novel biochemical factors in relation to prostate cancer incidence and mortality in UK Biobank. Br J Cancer. 2020 Sep 23;: Authors: Perez-Cornago A, Fensom GK, Andrews C, Watts EL, Allen NE, Martin RM, Van Hemelrijck M, Key TJ, Travis RC Abstract BACKGROUND: Although prostate cancer is a leading cause of cancer death, its aetiology is not well understood. We aimed to identify novel biochemical factors...
Related Articles Negative regulation between the expression levels of receptor for hyaluronic acid-mediated motility and hyaluronan leads to cell migration in pancreatic cancer. Oncol Lett. 2020 Nov;20(5):199 Authors: Cheng XB, Wang S, Yang H, Tong H, Shi G, Wu L, Zhou J, Shi L, Li H, Ren S, Zhou Y, Sato N Abstract Receptor for hyaluronic acid (HA)-mediated motility (RHAMM) expression is upregulated in pancreatic ductal adenocarcinoma (PDAC)....
Related Articles Urinary incontinence and quality of life: a systematic review and meta-analysis. Aging Clin Exp Res. 2020 Sep 22;: Authors: Pizzol D, Demurtas J, Celotto S, Maggi S, Smith L, Angiolelli G, Trott M, Yang L, Veronese N Abstract BACKGROUND: Urinary incontinence (UI) and low quality of life (QoL) are two common conditions. Some recent literature proposed that these two entities can be associated. However, no attempt was made to...
Related Articles Intensity-Modulated Proton Therapy (IMPT) Interplay Effect Evaluation of Asymmetric Breathing with Simultaneous Uncertainty Considerations in Patients with Non-Small Cell Lung Cancer. Med Phys. 2020 Sep 22;: Authors: Shan J, Yang Y, Schild SE, Daniels TB, Wong WW, Fatyga M, Bues M, Sio TT, Liu W Abstract PURPOSE: Intensity-modulated proton therapy (IMPT) is sensitive to uncertainties from patient setup and proton beam range,...
Related Articles Acute and cumulative benefits of Photobiomodulation for xerostomia: a systematic review and meta-analysis. Oral Dis. 2020 Sep 22;: Authors: Galiano-Castillo N, Liu L, Lozano-Lozano M, Tumilty S, Cantarero-Villanueva I, Baxter GD Abstract The objective was to explore the effectiveness of photobiomodulation therapy for treating patients who suffer xerostomia and/or hyposalivation due to the most prevalent clinical diagnoses. We...
Related Articles Consensus paper: current state of first- and second-line therapy in advanced clear-cell renal cell carcinoma. Future Oncol. 2020 Sep 23;: Authors: Goebell PJ, Ivanyi P, Bedke J, Bergmann L, Berthold D, Boegemann M, Busch J, Doehn C, Krege S, Retz M, Amsberg GV, Grimm MO, Gruenwald V Abstract The therapy of advanced (clear-cell) renal cell carcinoma (RCC) has recently experienced tremendous changes. Several new treatments have...
Related Articles Alpelisib in the treatment of metastatic HR+ breast cancer with PIK3CA mutations. Future Oncol. 2020 Sep 23;: Authors: Mavratzas A, Marmé F Abstract Since the US FDA approval of everolimus/exemestane in July 2012, and of the first CDK 4/6 inhibitor, palbociclib, combined with endocrine treatment in February 2015, a third class of therapeutic compounds, the PI3K inhibitors, has been introduced to the arsenal of targeted therapies...
Related Articles Are COVID-19 Delays a Basis for Concern? Can We Use This for Future Good? Oncology (Williston Park). 2020 Sep 15;34(9):344-345 Authors: Moul JW Abstract Judd W. Moul, MD, discusses the effects that COVID-19 may have on the outcomes for patients with cancer in the United States and throughout the world. PMID: 32965663 [PubMed - as supplied by publisher]
Related Articles Is Telehealth Here To Stay. Oncology (Williston Park). 2020 Sep 15;34(9):377-378 Authors: Abstract The telehealth explosion was facilitated by the onset of the coronavirus disease 2019 (COVID-19) pandemic, but what happens when the crisis is over? Will there be lasting changes to the practice of medicine and delivery of care, or will providers and patients alike be eager to go back to the "old way" of doing things? Jeremy Gabrysch,...
Related Articles Wound Healing Driver Gene (WDG) and Therapeutic Development: Political and Scientific Hurdles. Adv Wound Care (New Rochelle). 2020 Sep 23;: Authors: Tang X, Hao M, Cheng C, Bhatia A, O'Brien K, Chen M, Armstrong DG, Li W Abstract SIGNIFICANCE: Since the last FDA approval of a wound healing therapeutic in 1997, no new therapeutic candidate (excluding physical therapies, devices, dressings and antimicrobial agents) has advanced...
Related Articles Adding the temporal domain to PET radiomic features. PLoS One. 2020;15(9):e0239438 Authors: Noortman WA, Vriens D, Slump CH, Bussink J, Meijer TWH, de Geus-Oei LF, van Velden FHP Abstract BACKGROUND: Radiomic features, extracted from positron emission tomography, aim to characterize tumour biology based on tracer intensity, tumour geometry and/or tracer uptake heterogeneity. Currently, radiomic features are derived from static...
Related Articles Behavioral determinants of Canadian radiation oncologists' use of single fraction palliative radiation therapy for uncomplicated bone metastases. Int J Radiat Oncol Biol Phys. 2020 Sep 20;: Authors: Squires JE, Asad S, Varin MD, Dorrance K, Chow E, Fairchild A, Wong R, Graham ID, Grimshaw JM, Dennis K Abstract BACKGROUND: A mainstay therapy for pain relief from uncomplicated bone metastases is external beam radiation therapy....
Related Articles Feasibility study of cryobiopsy for practical pathological diagnosis of primary lung cancer including immunohistochemical assessment. Jpn J Clin Oncol. 2020 Sep 23;: Authors: Nishida T, Matsumoto Y, Sasada S, Tanaka M, Nakai T, Fukai R, Ohe Y, Watanabe SI, Motoi N Abstract BACKGROUND: Precision medicine in non-small cell lung cancer requires attainment of a sufficient amount of high-quality tumor tissue. Transbronchial cryobiopsy...
Abstract Cancer‐derived myocardial damage is an important cause of death in cancer patients. However, the development of dietary interventions for treating such damage has not been advanced. Here, we investigated the effect of dietary intervention with lauric acid (LAA) and glucose, which was effective against skeletal muscle sarcopenia in a mouse cachexia model, on myocardial damage. Treatment of H9c2 rat cardiomyoblasts with lauric acid promoted mitochondrial respiration and increased ATP production...
Abstract Our laboratory previously reported the usefulness of exosomes in the plasma of esophageal squamous cell carcinoma (ESCC) patients as a biomarker. However, the influence of tumor‐derived exosomes on the tumor itself and underlying mechanisms remain unclear. We herein report the changes in the phenotype and gene expression when cancer cells exist in an environment with tumor‐derived exosomes. The exosomes were isolated from the culture medium of human ESCC cells (TE2, T.Tn) by ultracentrifugation,...
AbstractHoneybees rely on nectar as their main source of carbohydrates. Sucrose, glucose and fructose are the main components of plant nectars. Intriguingly, honeybees express only three putative sugar receptors (AmGr1, AmGr2 and AmGr3), which is in stark contrast to many other insects and vertebrates. The sugar receptors are only partially characterized. AmGr1 detects different sugars including sucrose and glucose. AmGr2 is assumed to act as a co-receptor only, while AmGr3 is assumedly a fructose...
Related Articles Beneficial effect of black rice ( Oryza sativa L. var. japonica ) extract on amyloid β-induced cognitive dysfunction in a mouse model. Exp Ther Med. 2020 Nov;20(5):64 Authors: Lee AY, Choi JM, Lee YA, Shin SH, Cho EJ Abstract Alzheimer's disease (AD) is an age-dependent progressive neurodegenerative disease, resulting in memory loss and cognitive dysfunction. The accumulation of amyloid β (Aβ) has been identified as the most...
circKMT2D contributes to H2O2-attenuated osteosarcoma progression via the miR-210/autophagy pathway.
Related Articles circKMT2D contributes to H2O2-attenuated osteosarcoma progression via the miR-210/autophagy pathway. Exp Ther Med. 2020 Nov;20(5):65 Authors: Zhang J, Chou X, Zhuang M, Zhu C, Hu Y, Cheng D, Liu Z Abstract Circular RNAs (circRNAs) have been demonstrated to be involved in osteosarcoma (OS) development; however, the underlying mechanism of circKMT2D in OS progression remains unclear. The present study aimed to elucidate how circKMT2D...
Related Articles Stent retriever thrombectomy combined with long-term local thrombolysis for severe hemorrhagic cerebral venous sinus thrombosis. Exp Ther Med. 2020 Nov;20(5):66 Authors: Wang Y, Zhao C, Huang D, Sun B, Wang Z Abstract Cerebral venous sinus thrombosis (CVST) is a rare disease associated with high disability and mortality rates. A subset of patients do not respond to standard anticoagulation therapy, leading to the progression...
Differential expression of peptides serves as an indicator of IgA nephropathy in pediatric patients.
Related Articles Differential expression of peptides serves as an indicator of IgA nephropathy in pediatric patients. Exp Ther Med. 2020 Nov;20(5):67 Authors: Rao C, Yang F, Lai Z, Chen S, Lu X, Jiang X Abstract Peptide profiles change significantly with aging and peptide biomarkers discovered in adult patients may not be suitable for the evaluation of pediatric patients. The present study was designed to explore alterations in the serum peptidome...
Related Articles miR-376c-3p modulates the properties of breast cancer stem cells by targeting RAB2A. Exp Ther Med. 2020 Nov;20(5):68 Authors: Zhao F, Zhong M, Pei W, Tian B, Cai Y Abstract MicroRNAs (miRNAs/miRs) negatively regulate gene expression and participate in various cellular processes. miRNA dysregulation is associated with cancer progression. The present study aimed to identify the miRNAs that participate in breast cancer tumorigenesis...
Related Articles Overexpression of long non-coding RNA nuclear enriched abundant transcript 1 inhibits the expression of p53 and improves premature ovarian failure. Exp Ther Med. 2020 Nov;20(5):69 Authors: Li M, Peng J, Zeng Z Abstract It has been previously reported that the long non-coding RNA nuclear enriched abundant transcript 1 (NEAT1) can regulate cell apoptosis. The present study aimed to investigate the involvement of NEAT1 in premature...
Related Articles CGA ameliorates cognitive decline by regulating the PI3K/AKT signaling pathway and neurotransmitter systems in rats with multi-infarct dementia. Exp Ther Med. 2020 Nov;20(5):70 Authors: Fu Y, Wei J, Li B, Gao L, Xia P, Wen Y, Xu S Abstract Multi infarct dementia (MID) is a form of dementia that is preventable and treatable. However, at present, the drugs used in MID treatment were developed for Alzheimer's disease. While only...
Related Articles Hypertonic saline improves brain edema resulting from traumatic brain injury by suppressing the NF-κB/IL-1β signaling pathway and AQP4. Exp Ther Med. 2020 Nov;20(5):71 Authors: Zhang H, Liu J, Liu Y, Su C, Fan G, Lu W, Feng L Abstract Although hypertonic saline (HS) has been extensively applied to treat brain edema in the clinic, the precise mechanism underlying its function remains poorly understood. Therefore, the aim of the...
Related Articles Paclitaxel inhibits the migration of CD133+ U251 malignant glioma cells by reducing the expression of glycolytic enzymes. Exp Ther Med. 2020 Nov;20(5):72 Authors: Long N, Peng S, Chu L, Jia J, Dong M, Liu J Abstract Energy metabolic reprogramming (EMR) allows for the rearrangement of a series of metabolic genes and proteins when tumor cells adapt to their microenvironment. EMR is characterized by changes in the metabolic pattern...
Abstract Objectives During the current COVID‐19 pandemic, the demand for direct‐to‐home telemedicine services has risen to an unprecedented level. Equal access to specialty care was assessed to identify potential barriers that may negatively impact telemedicine utilization. Methods We examined the 6‐week period between March and May 2020 when the only access to non‐urgent pediatric otolaryngology service was through telemedicine and compared it to in‐person visits during the same period...
25 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/09/24PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Related Articles [Comparison of clinical effects of two anterior cervical decompression with fusion on treating two segment cervical spondylotic myelopathy]. Zhongguo Gu Shang. 2020 Sep 25;33(9):841-7 Authors: Chen EL, Wang N, Quan RF Abstract OBJECTIVE: To explore the clinical effects of anterior cervical discectomy with fusion (ACDF) and anterior cervical corpectomy with fusion (ACCF) in treating adjacent two-segment cervical spondylotic myelopathy...
Related Articles Uterine preservation in pelvic organ prolapse and urinary stress incontinence using robot-assisted laparoscopic surgery. Case report. Int J Surg Case Rep. 2020 Sep 04;: Authors: Cucinella G, Culmone S, Guastella E, Gentile F, Francesca M, Granà R, Carlisi B, Rotolo S, Calagna G Abstract INTRODUCTION: To report a case of uterine preservation in pelvic organ prolapse robot-assisted laparoscopic surgery. PRESENTATION OF...
Related Articles Vasomotor changes in abdominal skin after endoscopic subcutaneous/Preaponeurotic Repair of Diastasis Recti (REPA). Int J Surg Case Rep. 2020 Sep 03;75:182-184 Authors: Hanssen A, Palmisano EM, Hanssen DA, Hanssen RA, Daes JE Abstract INTRODUCTION: Diastasis recti is a common condition with functional and cosmetic effects that can occur in both female and male patients. However, it is more prevalent in females after pregnancies...
Related Articles A case of thymic basaloid carcinoma with rectal carcinoma. Int J Surg Case Rep. 2020 Sep 12;75:185-188 Authors: Fukunaga A, Sasamura Y, Murakami Y, Abe H, Hontani K, Kubota T Abstract INTRODUCTION: Thymic basaloid carcinoma is rare, as only about 40 reports have described it since the initial report. Thymoma and thymic carcinomas increase the risk of other malignancies, but concurrent thymic basaloid carcinoma and another malignancy...
Related Articles Crossed testicular ectopia: Case report with review of literature. Int J Surg Case Rep. 2020 Sep 13;75:189-192 Authors: Jabali SS, Mohammed AA Abstract BACKGROUND: Crossed testicular ectopia is a rare form of urogenital anomalies in which both testes are migrated and descend through a single inguinal canal, one or both testes may be ectopic in the abdomen, the inguinal region or descent to the hemi-scrotum with empty contralateral...
Related Articles Torsion of a giant pedunculated liver hemangioma: Case report. Int J Surg Case Rep. 2020 Sep 14;75:207-210 Authors: Castañeda Puicón L, Trujillo Loli Y, Campos Medina S Abstract INTRODUCTION: Hepatic hemangioma (HH) is the most common benign neoplasm affecting the liver. Most cases are asymptomatic and incidentally found at imaging studies. Giant hepatic hemangiomas are uncommon, but pedunculated giant hemangiomas are even rarer,...
Related Articles Rare presentation of community acquired pneumonia resulted in laparoscopic intervention in adult. Case Report. Int J Surg Case Rep. 2020 Sep 14;75:214-218 Authors: Naccour J, Sabra H, Alimoradi M, El-Helou E, Haddad MM, Bitar H Abstract INTRODUCTION: Community acquired pneumonia usually presents with typical clinical and radiological signs allowing for a quick diagnosis. Nevertheless, pneumonia can infrequently mimic acute abdominal...
Related Articles Incidental finding of double appendix during laparotomy for intussusception: A case report. Int J Surg Case Rep. 2020 Sep 14;75:219-221 Authors: Olarinoye-Alegbejo MI, Steve K, Ologun GO Abstract INTRODUCTION: A double caecal appendix is an uncommon anatomical variation with significant surgical implications. A few cases of the double caecal appendix have been reported worldwide, mostly in adults. The diagnosis is, usually incidental,...
Related Articles A novel technique of laparoscopic reduction of incarcerated internal supravesical hernia via peritoneal incision: A case report. Int J Surg Case Rep. 2020 Sep 15;75:222-226 Authors: Matsui Y, Murakami T, Horita K, Ishida S, Matsuda S, Tayama A, Sakata R Abstract INTRODUCTION: Laparoscopic reduction techniques for internal supravesical hernia have not been discussed much in literature. CASE PRESENTATION: A 90-year old...
Related Articles Congenital partial pericardial defect confirmed based on spontaneous pneumothorax: A case report and literature review. Int J Surg Case Rep. 2020 Sep 15;75:227-230 Authors: Date N, Komatsu T, Fujinaga T Abstract INTRODUCTION: Congenital pericardial defects are rare but can cause fatal complications. Most cases are asymptomatic and incidentally detected during a thoracic surgery or autopsy. We report a case of a partial pericardial...
Related Articles A rare case of pre-hospital globe enucleation after a penetrating injury to the orbit during an assault: A case report and literature review. Int J Surg Case Rep. 2020 Sep 15;75:231-234 Authors: Elkbuli A, Meneses E, Kinslow K, McKenney M, Boneva D Abstract INTRODUCTION: Ocular trauma is a common occurrence in trauma settings but often occurs with little to no effect on the vision of the patient. Traumatic enucleation is a rare...
Related Articles Case report: Back pseudocyst of unknown origin. Int J Surg Case Rep. 2020 Aug 29;75:235-237 Authors: Moussally M, Khalifeh J, Mokalled I, Faraj W, Khalife MJ Abstract INTRODUCTION: Soft tissue masses are fairly encountered clinical entities. Among the rare forms of soft tissues masses are non-pancreatic pseudocysts which are defined as encapsulated fluid collections not lined by epithelium. We are presenting a rare case of a...
Related Articles An association between successful engraftment of osteosarcoma patient-derived xenografts and clinicopathological findings. Histol Histopathol. 2020 Sep 23;:18256 Authors: Fortuna-Costa A, Granato RA, Meohas W, Lopes ACS, Caruso AC, Pinheiro RCES, d'Eça PDG, Dias RB, Perini JA, Barbosa APF, de Sá RAM, Guimarães JAM, Murray SS, Duarte MEL Abstract Although osteosarcoma is a rare disease, with a global incidence rate estimated...
Related Articles Targeting metabotropic glutamate receptors for rapid-acting antidepressant drug discovery. Expert Opin Drug Discov. 2020 Sep 23;:1-11 Authors: Musazzi L Abstract INTRODUCTION: Depression is a highly debilitating psychiatric disorder and a worldwide health issue. Functional deficits in glutamatergic cortico-limbic areas are hypothesized to play a key role in the pathogenesis of the disease. Consistently, the clinical antidepressant...
Related Articles Direct Peritoneal Resuscitation Improves Survival in a Murine Model of Combined Hemorrhage and Burn Injury. Mil Med. 2020 Sep 18;185(9-10):e1528-e1535 Authors: Jung AD, Friend LA, Stevens-Topie S, Schuster R, Lentsch AB, Gavitt B, Caldwell CC, Pritts TA Abstract INTRODUCTION: Combined burn injury and hemorrhagic shock are a common cause of injury in wounded warfighters. Current protocols for resuscitation for isolated burn injury...
Related Articles Letter From Executive Director Dr. John Cho. Mil Med. 2020 Sep 18;185(9-10):1-2 Authors: PMID: 32964239 [PubMed - as supplied by publisher]
Prostate cancer (PCa) is one of the most commonly diagnosed cancers in males worldwide. lncRNAs (long noncoding RNAs) play a significant role in the occurrence and development of PCa. eRNAs (enhancer RNAs) and SE-lncRNAs (superenhancer lncRNAs) are important elements of lncRNAs, but the role of eRNAs and SE-lncRNAs in PCa remains largely unclear. In this work, we identified 681 eRNAs and 292 SE-lncRNAs that were expressed differentially in PCa using a microarray. We also found that eRNAs transcribed...
Background. The pathogenesis of thoracic aortopathy is complex, and much evidence suggests the influence of genetic factors. Some genes with polymorphisms are widely considered critical factors in the initiation and development of aortic aneurysm. The aim of our study was to analyze the association of genetic polymorphisms of MMP1 rs1799750 (c.-1607G>GG), MMP9 rs3918242 (c.-1562C>T), COL1A1 rs1800012 (c.1245G>T), and COL1A2 rs42524 (c.1645G>C) with predisposition to thoracic aortopathy...
Publication date: Available online 23 September 2020Source: Journal of Oral and Maxillofacial SurgeryAuthor(s): Anson Jose, Poonam Yadav, Ajoy Roychoudhury, Ongkila Bhutia, Tabin Millo, Ravinder Mohan Pandey
Related Articles A Severe COVID-19 Case Complicated by Right Atrium Thrombus. Am J Case Rep. 2020 Sep 23;21:e926915 Authors: Anthi A, Konstantonis D, Theodorakopoulou M, Apostolopoulou O, Karampela I, Konstantopoulou G, Patsilinakou S, Armaganidis A, Dimopoulos G Abstract BACKGROUND Recent studies demonstrated evidence of coagulation dysfunction in hospitalized patients with severe coronavirus disease 2019 (COVID-19) due to excessive inflammation,...
Related Articles Take Me Higher: A Case of Heart Failure at High Altitude Detected Using the CardioMEMS™ HF System. Am J Case Rep. 2020 Sep 23;21:e922857 Authors: Letourneau MM, Brancheau D, Estes J, Zughaib M Abstract BACKGROUND The heart failure patient population can be challenging to treat and monitor. This is especially true when they travel to high altitudes where changes in pressure can affect their clinical status. The CardioMEMS™ HF...
Related Articles Analysis of Differential Expression of Synaptic Vesicle Protein 2A in the Adult Rat Brain. Neuroscience. 2019 11 01;419:108-120 Authors: Mendoza-Torreblanca JG, García-Cruz ME, Sánchez-Cruz I, Gomez-Gonzalez B, Juárez-Méndez S, Gómez-Lira G Abstract Synaptic vesicle protein 2A (SV2A), which plays an important role in the pathophysiology of epilepsy, is a unique vesicular protein recognized as a pharmacological target of anticonvulsant...
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