Introducing Human Adipose-Derived Mesenchymal Stem Cells to Avance® Nerve Grafts and NeuraGen® Nerve Guides

Introducing Human Adipose-Derived Mesenchymal Stem Cells to Avance® Nerve Grafts and NeuraGen® Nerve Guides: When direct nerve coaptation is impossible after peripheral nerve injury, autografts, processed allografts, or conduits are used to bridge the nerve gap. The purpose of this study was to examine if human adipose-derived Mesenchymal Stromal/Stem Cells (MSCs) could be introduced to commercially available nerve graft substitutes and to determine cell distribution and the seeding efficiency of a dynamic seeding strategy.