Antibiotics, Vol. 9, Pages 270: Isolation, Characterization and Chemical Synthesis of Large Spectrum Antimicrobial Cyclic Dipeptide (l-leu-l-pro) from Streptomyces misionensisV16R3Y1 Bacteria Extracts. A Novel 1H NMR Metabolomic Approach Antibiotics doi: 10.3390/antibiotics9050270 Authors: Saadouli Zendah El Euch Trabelsi Mosbah Redissi Ferjani Fhoula Cherif Sabatier Sewald Ouzari Streptomyces is the most frequently described genus of Actinomycetes,...
Antibiotics, Vol. 9, Pages 268: Phages for Biofilm Removal Antibiotics doi: 10.3390/antibiotics9050268 Authors: Celia Ferriol-González Pilar Domingo-Calap Biofilms are clusters of bacteria that live in association with surfaces. Their main characteristic is that the bacteria inside the biofilms are attached to other bacterial cells and to the surface by an extracellular polymeric matrix. Biofilms are capable of adhering to a wide variety of surfaces, both biotic and abiotic, including...
Antibiotics, Vol. 9, Pages 269: The Israeli Phage Bank (IPB) Antibiotics doi: 10.3390/antibiotics9050269 Authors: Ortal Yerushalmy Leron Khalifa Naama Gold Chani Rakov Sivan Alkalay-Oren Karen Adler Shira Ben-Porat Reut Kraitman Niv Gronovich Kerem Shulamit Ginat Mohanad Abdalrhman Shunit Coppenhagen-Glazer Ran Nir-Paz Ronen Hazan A key element in phage therapy is the establishment of large phage collections, termed herein “banks”,...
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Antioxidants, Vol. 9, Pages 445: One-Week High-Intensity Interval Training Increases Hippocampal Plasticity and Mitochondrial Content without Changes in Redox State Antioxidants doi: 10.3390/antiox9050445 Authors: Jonathas Rodrigo dos Santos Mariza Bortolanza Gustavo Duarte Ferrari Guilherme Pauperio Lanfredi Glauce Crivelaro do Nascimento Ana Elisa Calereiro Seixas Azzolini Elaine Del Bel Alline Cristina de Campos Vitor Marcel Faça Anderson Vulczak Luciane Carla...
Antioxidants, Vol. 9, Pages 446: Protective Effects of Myricetin on Benzo[a]pyrene-Induced 8-Hydroxy-2′-Deoxyguanosine and BPDE-DNA Adduct Antioxidants doi: 10.3390/antiox9050446 Authors: Seung-Cheol Jee Min Kim Kyeong Seok Kim Hyung-Sik Kim Jung-Suk Sung Benzo[a]pyrene (B[a]P), a group 1 carcinogen, induces mutagenic DNA adducts. Myricetin is present in many natural foods with diverse biological activities, such as anti-oxidative and anti-cancer activities. The aim of this...
Antioxidants, Vol. 9, Pages 444: Effects of Advanced Age, Pituitary Pars Intermedia Dysfunction and Insulin Dysregulation on Serum Antioxidant Markers in Horses Antioxidants doi: 10.3390/antiox9050444 Authors: Agnieszka Żak Natalia Siwińska Elżbieta Chełmecka Barbara Bażanów Ewa Romuk Amanda Adams Artur Niedźwiedź Dominika Stygar The study aims to assess the impact of age, pituitary pars intermedia dysfunction (PPID) and insulin dysregulation (ID) in horses on selected...
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Arts, Vol. 9, Pages 63: Synagogue Objects Related to Charity on Shabbat: Shnoder-Signs and Shnoder-Books in the Hungarian Lands Arts doi: 10.3390/arts9020063 Authors: Bányai Komoróczy In Ashkenazi Jewish communities, it is customary to promise a donation to charitable causes after being called up to the Torah on Shabbat and on holidays—there is even a Yiddish term for it: shnodern. In our article, we will look at various synagogue objects related to this type of charity,...
Arts, Vol. 9, Pages 62: Lithuanian Synagogues: From the First Descriptions to Systematic Research Arts doi: 10.3390/arts9020062 Authors: Gradinskaite The article presents an analysis of the development stages of synagogue research methodology in Lithuania during the four major historical periods of the country—Lithuania in the Russian Empire (1795–1918), Vilnius Region in the interwar period and the independent Republic of Lithuania (1918–1940), the Soviet...
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Atmosphere, Vol. 11, Pages 537: Long-Term Trends of Air Pollution at National Atmospheric Observatory Košetice (ACTRIS, EMEP, GAW) Atmosphere doi: 10.3390/atmos11050537 Authors: Váňa Holubová Smejkalová Svobodová Machálek The National Atmospheric Observatory Košetice operated by the Czech Hydrometeorological Institute was established in 1988 as a station specializing in air quality monitoring at the background scale. The observatory is located in the free area...
Atmosphere, Vol. 11, Pages 536: Applying a Delphi-Type Approach to Estimate the Adaptation Cost on Agriculture to Climate Change in Cyprus Atmosphere doi: 10.3390/atmos11050536 Authors: Markou Michailidis Loizou Nastis Lazaridou Kountios Allahyari Stylianou Papadavid Mattas Agriculture is highly dependent on climate change, and Cyprus especially is experiencing its impacts on agricultural production to a greater extent, mainly due to its geographical...
Atmosphere, Vol. 11, Pages 535: Climate Scenarios and Agricultural Indices: A Case Study for Switzerland Atmosphere doi: 10.3390/atmos11050535 Authors: Flavian Tschurr Iris Feigenwinter Andreas M. Fischer Sven Kotlarski The CH2018 Climate Scenarios for Switzerland are evaluated with respect to the representation of 24 indices with agricultural relevance. Furthermore, future projections of the considered indices until the end of the 21st century are analyzed for two greenhouse...
Atmosphere, Vol. 11, Pages 533: Mineral Dust and Iron Solubility: Effects of Composition, Particle Size, and Surface Area Atmosphere doi: 10.3390/atmos11050533 Authors: Aurelie R. Marcotte Ariel D. Anbar Brian J. Majestic Pierre Herckes There is significant iron deposition in the oceans, approximately 14–16 Tg annually from mineral dust aerosols, but only a small percentage (approx. 3%) of it is soluble and, thus, bioavailable. In this work, we examine the effect of...
Atmosphere, Vol. 11, Pages 531: Some Aspects of the Scattering of Light and Microwaves on Non-Spherical Raindrops Atmosphere doi: 10.3390/atmos11050531 Authors: Victor V. Sterlyadkin A review of the author’s work on the study of the microphysics of rain is carried out. The effect of an anomalously high modulation of light scattered by oscillating drops of water, which consists in the formation of powerful pulses of light when illuminating an oscillating drop with continuous...
Atmosphere, Vol. 11, Pages 534: Ozone Trends in the United Kingdom over the Last 30 Years Atmosphere doi: 10.3390/atmos11050534 Authors: Florencia M. R. Diaz M. Anwar H. Khan Beth M. A. Shallcross Esther D. G. Shallcross Ulrich Vogt Dudley E. Shallcross Previous work regarding the behaviour of ozone surface concentrations over many years in the United Kingdom had predicted that the frequency and severity of ozone episodes would become less marked in the future as a response...
Atmosphere, Vol. 11, Pages 532: Investigation of the Successive Ozone Episodes in the El Paso–Juarez Region in the Summer of 2017 Atmosphere doi: 10.3390/atmos11050532 Authors: Karle Mahmud Sakai Fitzgerald Morris Stockwell The adjacent cities of El Paso in Texas, USA, and Juarez in Mexico commonly experience pollution episodes, especially during the summer months. In the summer of 2017, successive high and low ozone episodes were observed. Aerosol backscattered...
Atmosphere, Vol. 11, Pages 530: Field Survey on Concentration and Emission of Dust in Different Types of Poultry Houses of South Korea Atmosphere doi: 10.3390/atmos11050530 Authors: Ki Youn Kim Han Jong Ko The dust generated from poultry houses has an adverse effect on farmers and poultry in terms of hygiene and welfare problems. However, there is little information on concentration and emission of dust derived from poultry houses located in South Korea. An objective of this study...
Atmosphere, Vol. 11, Pages 529: Dynamics of Muddy Rain of 15 June 2018 in Nepal Atmosphere doi: 10.3390/atmos11050529 Authors: Ashok Kumar Pokharel Tianli Xu Xiaobo Liu Binod Dawadi It has been revealed from the Modern-Era Retrospective analysis for Research and Applications MERRA analyses, Moderate Resolution Imaging Spectroradiometer MODIS/Terra satellite imageries, Naval Aerosol Analysis and Prediction System NAAPS model outputs, Cloud –Aerosol Lidar and Infrared...
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Bioengineering, Vol. 7, Pages 45: Copper-doped Ordered Mesoporous Bioactive Glass: A Promising Multifunctional Platform for Bone Tissue Engineering † Bioengineering doi: 10.3390/bioengineering7020045 Authors: Francesco Baino The design and development of biomaterials with multifunctional properties is highly attractive in the context of bone tissue engineering due to the potential of providing multiple therapies and, thus, better treatment of diseases. In order to tackle this challenge,...
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Biology, Vol. 9, Pages 109: Brain Control Reproduction by the Endocrine System of Female Blue Gourami (Trichogaster trichopterus) Biology doi: 10.3390/biology9050109 Authors: Degani Blue gourami belongs to the Labyrinithici fish and the Anabantiform order. It is characterized by a specific organ located above its gills for the respiration of atmospheric oxygen. This specific adaptation to low oxygen levels affects reproduction that is controlled by the brain, which integrates different...
Biology, Vol. 9, Pages 107: Novel Dynamic Structures of 2019-nCoV with Nonlocal Operator via Powerful Computational Technique Biology doi: 10.3390/biology9050107 Authors: Wei Gao P. Veeresha D. G. Prakasha Haci Mehmet Baskonus In this study, we investigate the infection system of the novel coronavirus (2019-nCoV) with a nonlocal operator defined in the Caputo sense. With the help of the fractional natural decomposition method (FNDM), which is based on the Adomian decomposition...
Biology, Vol. 9, Pages 108: Clinical Genetics of Prolidase Deficiency: An Updated Review Biology doi: 10.3390/biology9050108 Authors: Marta Spodenkiewicz Michel Spodenkiewicz Maureen Cleary Marie Massier Giorgos Fitsialos Vincent Cottin Guillaume Jouret Céline Poirsier Martine Doco-Fenzy Anne-Sophie Lèbre Prolidase is a ubiquitous enzyme that plays a major role in the metabolism of proline-rich proteins. Prolidase deficiency is a rare autosomal recessive inborn...
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Biomedicines, Vol. 8, Pages 129: Tripartite Combination of Candidate Pandemic Mitigation Agents: Vitamin D, Quercetin, and Estradiol Manifest Properties of Medicinal Agents for Targeted Mitigation of the COVID-19 Pandemic Defined by Genomics-Guided Tracing of SARS-CoV-2 Targets in Human Cells Biomedicines doi: 10.3390/biomedicines8050129 Authors: Gennadi V. Glinsky Genes required for SARS-CoV-2 entry into human cells, ACE2 and FURIN, were employed as baits to build genomic-guided molecular...
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Biomolecules, Vol. 10, Pages 798: Galectin-3: Roles in Neurodevelopment, Neuroinflammation, and Behavior Biomolecules doi: 10.3390/biom10050798 Authors: Srejovic Selakovic Jovicic Jakovljević Lukic Rosic : There is a plethora of evidence to suggest that Galectin-3 plays an important role in normal functions of mammalian cells, as well as in different pathogenic conditions. This review highlights recent data published by researchers, including our own team, on roles...
Biomolecules, Vol. 10, Pages 799: In Vitro Anti-Inflammatory, Anti-Oxidant, and Cytotoxic Activities of Four Curcuma Species and the Isolation of Compounds from Curcuma aromatica Rhizome Biomolecules doi: 10.3390/biom10050799 Authors: Pintatum Maneerat Logie Tuenter Sakavitsi Pieters Berghe Sripisut Deachathai Laphookhieo The genus Curcuma is part of the Zingiberaceae family, and many Curcuma species have been used as traditional medicine and cosmetics...
Biomolecules, Vol. 10, Pages 797: Study of Synthesis Pathways of the Essential Polyunsaturated Fatty Acid 20:5n-3 in the Diatom Chaetoceros Muelleri Using 13C-Isotope Labeling Biomolecules doi: 10.3390/biom10050797 Authors: Remize Planchon Loh Grand Bideau Goic Fleury Miner Corvaisier Volety Soudant : The present study sought to characterize the synthesis pathways producing the essential polyunsaturated fatty acid (PUFA) 20:5n-3 (EPA). For this,...
Biomolecules, Vol. 10, Pages 796: Unstructured Biology of Proteins from Ubiquitin-Proteasome System: Roles in Cancer and Neurodegenerative Diseases Biomolecules doi: 10.3390/biom10050796 Authors: Kundlik Gadhave Prateek Kumar Shivani K. Kapuganti Vladimir N. Uversky Rajanish Giri The 26S proteasome is a large (~2.5 MDa) protein complex consisting of at least 33 different subunits and many other components, which form the ubiquitin proteasomal system (UPS), an ATP-dependent...
Biomolecules, Vol. 10, Pages 795: Characterization of Chenopodin Isoforms from Quinoa Seeds and Assessment of Their Potential Anti-Inflammatory Activity in Caco-2 Cells Biomolecules doi: 10.3390/biom10050795 Authors: Jessica Capraro Stefano De Benedetti Marina Di Dio Elisa Bona Ambra Abate Paola Antonia Corsetto Alessio Scarafoni Several food-derived molecules, including proteins and peptides, can show bioactivities toward the promotion of well-being and disease prevention...
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Brain Sciences, Vol. 10, Pages 312: Parental Education on Youth Inhibitory Control in the Adolescent Brain Cognitive Development (ABCD) Study: Blacks’ Diminished Returns Brain Sciences doi: 10.3390/brainsci10050312 Authors: Shervin Assari Background: Non-Hispanic Black (NHB) youth are at a higher risk of high-risk behaviors compared to non-Hispanic White (NHW) youth. Some of this racial gap is shown to be due to weaker effects of parental educational attainment on reducing the prevalence...
Brain Sciences, Vol. 10, Pages 311: Glutamatergic Fate of Neural Progenitor Cells of Rats with Inherited Audiogenic Epilepsy Brain Sciences doi: 10.3390/brainsci10050311 Authors: Naumova Oleynik Chernigovskaya Glazova Epilepsy is associated with aberrant neurogenesis in the hippocampus and may underlie the development of hereditary epilepsy. In the present study, we analyzed the differentiation fate of neural progenitor cells (NPC), which were isolated from the hippocampus...
Brain Sciences, Vol. 10, Pages 310: Transcranial Direct Current Stimulation to Facilitate Lower Limb Recovery Following Stroke: Current Evidence and Future Directions Brain Sciences doi: 10.3390/brainsci10050310 Authors: Samuel Gowan Brenton Hordacre Stroke remains a global leading cause of disability. Novel treatment approaches are required to alleviate impairment and promote greater functional recovery. One potential candidate is transcranial direct current stimulation (tDCS), which...
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Cancers, Vol. 12, Pages 1317: Transcriptional Regulation of CCL2 by PARP1 Is a Driver for Invasiveness in Breast Cancer Cancers doi: 10.3390/cancers12051317 Authors: Pranabananda Dutta Kimberly Paico Gabriela Gomez Yanyuan Wu Jaydutt V. Vadgama Background: PolyADP ribosylation (PARylation) by PARP1 is a significant post-translational modification affecting protein function in various cancers. However, PARP1 mediated cellular processes in the context of breast cancer are not...
Cancers, Vol. 12, Pages 1315: Clinical Implications of DNA Repair Defects in High-Grade Serous Ovarian Carcinomas Cancers doi: 10.3390/cancers12051315 Authors: Michela Camilla Milanesio Silvia Giordano Giorgio Valabrega Despite significant improvements in surgical and medical management, high grade serous ovarian cancer (HGSOC) still represents the deadliest gynecologic malignancy and the fifth most frequent cause of cancer-related mortality in women in the USA. Since DNA repair...
Cancers, Vol. 12, Pages 1314: Rafoxanide Induces Immunogenic Death of Colorectal Cancer Cells Cancers doi: 10.3390/cancers12051314 Authors: Antonio Di Grazia Federica Laudisi Davide Di Fusco Eleonora Franzè Angela Ortenzi Ivan Monteleone Giovanni Monteleone Carmine Stolfi Colorectal cancer (CRC) is a major cause of cancer-related death in the world. Emerging evidence suggests that the clinical success of conventional chemotherapy does not merely rely on cell toxicity,...
Cancers, Vol. 12, Pages 1313: PLZF-RARα, NPM1-RARα, and Other Acute Promyelocytic Leukemia Variants: The PETHEMA Registry Experience and Systematic Literature Review Cancers doi: 10.3390/cancers12051313 Authors: Marta Sobas Maria Carme Talarn-Forcadell David Martínez-Cuadrón Lourdes Escoda María J. García-Pérez Jose Mariz María J. Mela-Osorio Isolda Fernández Juan M. Alonso-Domínguez Javier Cornago-Navascués Gabriela Rodríguez-Macias María E. Amutio Carlos...
Cancers, Vol. 12, Pages 1312: Insight into the Development of PET Radiopharmaceuticals for Oncology Cancers doi: 10.3390/cancers12051312 Authors: Joseph Lau Etienne Rousseau Daniel Kwon Kuo-Shyan Lin François Bénard Xiaoyuan Chen While the development of positron emission tomography (PET) radiopharmaceuticals closely follows that of traditional drug development, there are several key considerations in the chemical and radiochemical synthesis, preclinical assessment, and...
Cancers, Vol. 12, Pages 1316: Relapse-Free Survival and PD-L1 Expression in First High- and Low-Grade Relapsed Luminal, Basal and Double-Negative P53-Mutant Non-Muscular Invasive Bladder Cancer Depending on Previous Chemo- and Immunotherapy Cancers doi: 10.3390/cancers12051316 Authors: Ekaterina Blinova Dmitry Enikeev Dmitry Roshchin Elena Samyshina Olga Deryabina Aleksander Tertychnyy Dmitry Blinov Evgenia Kogan Marina Dudina Haydar Barakat Dmitrij Merinov Aleksandr...
Cancers, Vol. 12, Pages 1301: Targeted Gene Delivery Therapies for Cervical Cancer Cancers doi: 10.3390/cancers12051301 Authors: Ángela Áyen Yaiza Jiménez Martínez Houria Boulaiz Despite being largely preventable through early vaccination and screening strategies, cervical cancer is the most common type of gynecological malignancy worldwide and constitutes one of the leading causes of cancer deaths in women. Patients with advanced or recurrent disease have a very poor prognosis;...
Cancers, Vol. 12, Pages 1310: Cysteine Cathepsins Inhibition Affects Their Expression and Human Renal Cancer Cell Phenotype Cancers doi: 10.3390/cancers12051310 Authors: Magdalena Rudzińska Alessandro Parodi Valentina D. Maslova Yuri M. Efremov Neonila V. Gorokhovets Vladimir A. Makarov Vasily A. Popkov Andrey V. Golovin Evgeni Y. Zernii Andrey A. Zamyatnin Renal cancer would greatly benefit from new therapeutic strategies since, in advanced stages, it is...
Cancers, Vol. 12, Pages 1304: A Simple Three-Dimensional In Vitro Culture Mimicking the In Vivo-Like Cell Behavior of Bladder Patient-Derived Xenograft Models Cancers doi: 10.3390/cancers12051304 Authors: Robson Amaral Maike Zimmermann Ai-Hong Ma Hongyong Zhang Kamilla Swiech Chong-Xian Pan Patient-derived xenograft (PDX) models allow for personalized drug selection and the identification of drug resistance mechanisms in cancer cells. However, PDX models present technical...
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