Storiform collagenoma (sclerotic fibroma) of the oral mucosa.

Storiform collagenoma (sclerotic fibroma) of the oral mucosa.:

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Storiform collagenoma (sclerotic fibroma) of the oral mucosa.

Br J Oral Maxillofac Surg. 2020 02;58(2):231-233

Authors: Elledge R, Nandra B, Bates T, Zardo D, Parmar S

Abstract

Storiform collagenoma (also called sclerotic fibroma) is uncommon, occurs as a cutaneous fibrous neoplasm, and is particularly rare in mucosal tissue in the head and neck. We describe an unexpected diagnosis in the oral cavity. Histopathological examination showed a proliferation of fibrous tissue, which was well circumscribed but unencapsulated, with thick laminated bundles of eosinophilic collagen that exhibited a storiform or "whorled" pattern. First described by Weary et al in 1972, storiform collagenoma is a marker for Cowden's disease or PTEN hamartoma tumour syndrome. Identification of other synchronous lesions should prompt chromosomal analysis for a mutation in the PTEN gene on chromosome 10q23.



PMID: 31761569 [PubMed - indexed for MEDLINE]