JCM, Vol. 9, Pages 185: Characterization and Analysis of the Skin Microbiota in Rosacea: Impact of Systemic Antibiotics Journal of Clinical Medicine doi: 10.3390/jcm9010185 Authors: Woo Lee Cho Lee Kim Systemic antibiotics are extensively used to control the papules and pustules of rosacea. Hence, it is crucial to understand their impact on the rosacea skin microbiota which is thought to be perturbed. The purpose of this study was to compare the makeup and diversity...
JCM, Vol. 9, Pages 184: The Immunomodulary Effects of Systematic Exercise in Older Adults and People with Parkinson’s Disease Journal of Clinical Medicine doi: 10.3390/jcm9010184 Authors: Szymura Kubica Wiecek Pera We sought to investigate whether regular balance training of moderate intensity (BT) has an effect on changes in selected cytokines, neurotrophic factors, CD200 and fractalkine in healthy older adults and participants with Parkinson’s disease (PD). Sixty-two...
JCM, Vol. 9, Pages 182: Chimeric Antigen Receptor T-Cell Therapy for Colorectal Cancer Journal of Clinical Medicine doi: 10.3390/jcm9010182 Authors: Sur Havasi Cainap Samasca Burz Balacescu Lupan Deleanu AlexandruIrimie Chimeric antigen receptor (CAR) T-cell therapy represents a new genetically engineered method of immunotherapy for cancer. The patient’s T-cells are modified to express a specific receptor that sticks to the tumor antigen. This...
JCM, Vol. 9, Pages 179: Sensitivity to Experiencing Alcohol Hangovers: Reconsideration of the 0.11% Blood Alcohol Concentration (BAC) Threshold for Having a Hangover Journal of Clinical Medicine doi: 10.3390/jcm9010179 Authors: Joris C. Verster L. Darren Kruisselbrink Karin A. Slot Aikaterini Anogeianaki Sally Adams Chris Alford Lizanne Arnoldy Elisabeth Ayre Stephanie Balikji Sarah Benson Gillian Bruce Lydia E. Devenney Michael R. Frone Craig Gunn Thomas...
JCM, Vol. 9, Pages 180: Genome-Wide Association Study of Opioid Cessation Journal of Clinical Medicine doi: 10.3390/jcm9010180 Authors: Jiayi W. Cox Richard M. Sherva Kathryn L. Lunetta Emma C. Johnson Nicholas G. Martin Louisa Degenhardt Arpana Agrawal Elliot C. Nelson Henry R. Kranzler Joel Gelernter Lindsay A. Farrer The United States is experiencing an epidemic of opioid use disorder (OUD) and overdose-related deaths. However, the genetic basis for the...
JCM, Vol. 9, Pages 181: Continuous Positive Airway Pressure Treatment in Patients with Alzheimer’s Disease: A Systematic Review Journal of Clinical Medicine doi: 10.3390/jcm9010181 Authors: Veronica Perez-Cabezas Carmen Ruiz-Molinero Jose Jesus Jimenez-Rejano Gloria Gonzalez-Medina Alejandro Galan-Mercant Rocio Martin-Valero Background: Epidemiological studies have suggested a pathophysiological relationship between obstructive sleep apnea syndrome (OSAS) and Alzheimer’s...
JCM, Vol. 9, Pages 178: Predictors for Target Vessel Failure after Recanalization of Chronic Total Occlusions in Patients Undergoing Surveillance Coronary Angiography Journal of Clinical Medicine doi: 10.3390/jcm9010178 Authors: Martin Geyer Johannes Wild Marc Hirschmann Zisis Dimitriadis Thomas Münzel Tommaso Gori Philip Wenzel (1) Background: Knowledge about predictors for the long-time patency of recanalized chronic total coronary occlusions (CTOs) is limited. Evidence...
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JFB, Vol. 11, Pages 3: Anti-Photoaging Effect of Plant Extract Fermented with Lactobacillus buchneri on CCD-986sk Fibroblasts and HaCaT Keratinocytes Journal of Functional Biomaterials doi: 10.3390/jfb11010003 Authors: Kang Hong Kang Seo Kim Lee Sim An Ultraviolet (UV) exposure triggers the abnormal production of reactive oxygen (ROS) species and the expression of matrix metalloproteinases (MMPs) that are responsible for photoaging. Probiotics are widely...
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Medicina, Vol. 56, Pages 26: Association of Serum Albumin and Severity of Pulmonary Embolism Medicina doi: 10.3390/medicina56010026 Authors: Omar Mirsaeidi Rashad Hassaballa Enten Helal Mangar Camporesi Background and Objectives: Inflammation is considered a risk factor for venous thromboembolism. The association between inflammatory markers and the severity of acute pulmonary embolism (APE) has not been explored. Methods: We studied the association between...
Medicina, Vol. 56, Pages 27: The Role of Cardiac T-Cadherin in the Indicating Heart Failure Severity of Patients with Non-Ischemic Dilated Cardiomyopathy Medicina doi: 10.3390/medicina56010027 Authors: Baltrūnienė Rinkūnaitė Bogomolovas Bironaitė Kažukauskienė Šimoliūnas Ručinskas Puronaitė Bukelskienė Grabauskienė Background and objectives: T-cadherin (T-cad) is one of the adiponectin receptors abundantly expressed in the heart and blood vessels....
Medicina, Vol. 56, Pages 25: Current Pharmacological Treatment of Painful Diabetic Neuropathy: A Narrative Review Medicina doi: 10.3390/medicina56010025 Authors: Ardeleanu Toma Pafili Papanas Motofei Diaconu Rizzo Stoian Background and Objectives: Distal symmetrical polyneuropathy (DSPN) is one of the most common chronic complications of diabetes mellitus. Although it is usually characterized by progressive sensory loss, some patients may develop chronic...
Medicina, Vol. 56, Pages 24: Challenges and Opportunities in Preclinical Research of Synthetic Cannabinoids for Pain Therapy Medicina doi: 10.3390/medicina56010024 Authors: Tamba Stanciu Urîtu Rezus Stefanescu Mihai Luca Rusu-Zota Leon-Constantin Cojocaru Gafton Alexa-Stratulat Cannabis has been used in pain management since 2900 BC. In the 20th century, synthetic cannabinoids began to emerge, thus opening the way for improved efficacy. The...
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Metabolites, Vol. 10, Pages 29: Biotransformation of Silymarin Flavonolignans by Human Fecal Microbiota Metabolites doi: 10.3390/metabo10010029 Authors: Kateřina Valentová Jaroslav Havlík Pavel Kosina Barbora Papoušková José Diógenes Jaimes Kristýna Káňová Lucie Petrásková Jitka Ulrichová Vladimír Křen Flavonolignans occur typically in Silybum marianum (milk thistle) fruit extract, silymarin, which contains silybin, isosilybin, silychristin, silydianin, and their...
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Microorganisms, Vol. 8, Pages 93: Peruvian chicha: A Focus on the Microbial Populations of This Ancient Maize-Based Fermented Beverage Microorganisms doi: 10.3390/microorganisms8010093 Authors: Daniela Bassi Luigi Orrù Jeison Cabanillas Vasquez Pier Sandro Cocconcelli Cecilia Fontana Peruvian chicha de jora is one of the most ancient traditional beverages produced through maize fermentation, still popular to modern consumers, but less studied in terms of microbial compositions....
Microorganisms, Vol. 8, Pages 92: On the Ability of Perfluorohexane Sulfonate (PFHxS) Bioaccumulation by Two Pseudomonas sp. Strains Isolated from PFAS-Contaminated Environmental Matrices Microorganisms doi: 10.3390/microorganisms8010092 Authors: Presentato Lampis Vantini Manea Daprà Zuccoli Vallini PFASs (perfluoroalkyl and polyfluoroalkyl substances) are highly fluorinated, aliphatic, synthetic compounds with high thermal and chemical stability as well as unique...
Microorganisms, Vol. 8, Pages 90: A High Resolution DNA Melting Curve Analysis for the Rapid and Efficient Molecular Diagnostics of Extended Spectrum β-Lactamase Determinants from Foodborne Escherichia coli Microorganisms doi: 10.3390/microorganisms8010090 Authors: Njage Buys The accurate identification of Extended-Spectrum β-Lactamase (ESBL) genes in Gram-negative bacteria is necessary for surveillance and epidemiological studies of transmission through foods. We report...
Microorganisms, Vol. 8, Pages 91: Metabolic Remodeling during Long-Lasting Cultivation of the Endomyces magnusii Yeast on Oxidative and Fermentative Substrates Microorganisms doi: 10.3390/microorganisms8010091 Authors: Elena P. Isakova Irina N. Matushkina Tatyana N. Popova Darya I. Dergacheva Natalya N. Gessler Olga I. Klein Anastasya V. Semenikhina Yulia I. Deryabina Nicola La Porta Nils-Eric L. Saris In this study, we evaluated the metabolic profile of the...
Microorganisms, Vol. 8, Pages 89: Diverse Stress-Inducing Treatments cause Distinct Aberrant Body Morphologies in the Chlamydia-Related Bacterium, Waddlia chondrophila Microorganisms doi: 10.3390/microorganisms8010089 Authors: Aurélie Scherler Nicolas Jacquier Carole Kebbi-Beghdadi Gilbert Greub Chlamydiae, such as Chlamydia trachomatis and Chlamydia pneumoniae, can cause chronic infections. It is believed that persistent forms called aberrant bodies (ABs) might be involved...
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Molecules, Vol. 25, Pages 282: Bioaffinity Fishing Procedure Using Secretory Phospholipase A2 for Screening for Bioactive Components: Modulation of Pharmacological Effect Induced by sPLA2 from Crotalus durissus terrificus by Hispidulin from Moquiniastrum floribundum Molecules doi: 10.3390/molecules25020282 Authors: dos Santos Junior Tamayose Ferreira Belchor Costa de Oliveira Toyama Bioaffinity capturing of molecules allows the discovery of bioactive compounds...
Molecules, Vol. 25, Pages 281: Effect of Ultrafiltration of Pitaya Extract (Stenocereus thurberi) on Its Phytochemical Content, Antioxidant Capacity, and UPLC-DAD-MS Profile Molecules doi: 10.3390/molecules25020281 Authors: Castro-Enríquez Montaño-Leyva Del Toro-Sánchez Juárez-Onofre Carvajal-Millán López-Ahumada Barreras-Urbina Tapia-Hernández Rodríguez-Félix Stenocereus thurberi is an endemic species in northwestern Mexico. It produces colorful fruits...
Molecules, Vol. 25, Pages 267: Erratum: Del Castillo, R.M., et al. Electronic Peculiarities of a Self-Assembled M12L24 Nanoball (M = Pd+2, Cr, or Mo). Molecules 2019, 24, 771 Molecules doi: 10.3390/molecules25020267 Authors: Roxana Mitzayé del Castillo Roberto Salcedo Ana Martínez Estrella Ramos Luis E. Sansores The author wishes to make the following correction to this paper [...]
Molecules, Vol. 25, Pages 279: Quality Control of Psoralea corylifolia L. Based on High-Speed Countercurrent Chromatographic Fingerprinting Molecules doi: 10.3390/molecules25020279 Authors: Wu Gao Liu Zhang Yang Zhu Song Li Chen Traditional Chinese medicine (TCM)has played an important role in promoting the health of Chinese people. The TCM Psoralea corylifolia L. has been used in the treatment of various kinds of diseases including enuresis, vitiligo,...
Molecules, Vol. 25, Pages 280: Solid-Phase Extraction of Catechins from Green Tea with Deep Eutectic Solvent Immobilized Magnetic Molybdenum Disulfide Molecularly Imprinted Polymer Molecules doi: 10.3390/molecules25020280 Authors: Ma Row A type of molecular-imprinted polymer with magnetic molybdenum disulfide as a base and deep eutectic solvent as a functional monomer (Fe3O4@MoS2@DES-MIP) was prepared with surface molecular imprinting method. It was applied as the adsorbent for...
Molecules, Vol. 25, Pages 276: Exploring the Multi-Target Performance of Mitochondriotropic Antioxidants against the Pivotal Alzheimer’s Disease Pathophysiological Hallmarks Molecules doi: 10.3390/molecules25020276 Authors: Benfeito Fernandes Vilar Remião Uriarte Borges Alzheimer disease (AD) is the most common neurodegenerative disease featuring progressive and degenerative neurological impairments resulting in memory loss and cognitive decline. The specific mechanisms...
Molecules, Vol. 25, Pages 278: Influence of Water Absorption on the Low Velocity Falling Weight Impact Damage Behaviour of Flax/Glass Reinforced Vinyl Ester Hybrid Composites Molecules doi: 10.3390/molecules25020278 Authors: Paturel Dhakal Due to rigorous new environmental legislations, automotive, marine, aerospace, and construction sectors have redirected their focus into using more recyclable, sustainable, and environmentally friendly lightweight materials driven by strengthening...
Molecules, Vol. 25, Pages 277: The Structural and Magnetic Properties of FeII and CoII Complexes with 2-(furan-2-yl)-5-pyridin-2-yl-1,3,4-oxadiazole Molecules doi: 10.3390/molecules25020277 Authors: Zoufalý Čižmár Kuchár Herchel Two novel coordination compounds containing heterocyclic bidentate N,N-donor ligand 2-(furan-2-yl)-5-(pyridin-2-yl)-1,3,4-oxadiazole (fpo) were synthesized. A general formula for compounds originating from perchlorates of iron, cobalt, and fpo can...
Molecules, Vol. 25, Pages 275: Pathogen Reduction Potential in Anaerobic Digestion of Organic Fraction of Municipal Solid Waste and Food Waste Molecules doi: 10.3390/molecules25020275 Authors: Przemysław Seruga Małgorzata Krzywonos Zbigniew Paluszak Agnieszka Urbanowska Halina Pawlak-Kruczek Łukasz Niedźwiecki Hanna Pińkowska Anaerobic digestion (AD) is a commonly used method of processing waste. Regardless of the type of the used digestate (fertilizer, feedstock in...
Molecules, Vol. 25, Pages 273: Synthesis of Chromium(II) Complexes with Chelating Bis(alkoxide) Ligand and Their Reactions with Organoazides and Diazoalkanes Molecules doi: 10.3390/molecules25020273 Authors: Sudheer S. Kurup Richard J. Staples Richard L. Lord Stanislav Groysman Synthesis of new chromium(II) complexes with chelating bis(alkoxide) ligand [OO]Ph (H2[OO]Ph = [1,1′:4′,1′’-terphenyl]-2,2′’-diylbis(diphenylmethanol))...
Molecules, Vol. 25, Pages 272: Revealing the Usefulness of Aroma Networks to Explain Wine Aroma Properties: A Case Study of Portuguese Wines Molecules doi: 10.3390/molecules25020272 Authors: Sílvia Petronilho Ricardo Lopez Vicente Ferreira Manuel A. Coimbra Sílvia M. Rocha Wine aroma is the result of complex interactions between volatile compounds and non-volatile ones and individual perception phenomenon. In this work, an aroma network approach, that links volatile composition...
Molecules, Vol. 25, Pages 274: A Novel Dual Fluorochrome Near-Infrared Imaging Probe for Potential Alzheimer’s Enzyme Biomarkers-BACE1 and Cathepsin D Molecules doi: 10.3390/molecules25020274 Authors: Jenny M. Tam Lee Josephson Alexander R. Pilozzi Xudong Huang A molecular imaging probe to fluorescently image the β-site of the amyloid precursor protein (APP) cleaving enzyme 1 (BACE1) and cathepsin D (CatD) enzymes associated with Alzheimer’s disease (AD) was...
Molecules, Vol. 25, Pages 270: A Non-Vector Approach to Increase Lipid Levels in the Microalga Planktochlorella nurekis Molecules doi: 10.3390/molecules25020270 Authors: Ewa Szpyrka Daniel Broda Bernadetta Oklejewicz Magdalena Podbielska Magdalena Slowik-Borowiec Bartosz Jagusztyn Grzegorz Chrzanowski Malgorzata Kus-Liskiewicz Magdalena Duda Janusz Zuczek Maciej Wnuk Anna Lewinska Microalgae are freshwater and marine unicellular photosynthetic organisms...
Molecules, Vol. 25, Pages 268: Rhodium(III)-Catalyzed Redox-Neutral [3+3] Annulation of N-nitrosoanilines with Cyclopropenones: A Traceless Approach to Quinolin-4(1H)-One Scaffolds Molecules doi: 10.3390/molecules25020268 Authors: Lingjun Liu Jiyuan Li Wenhao Dai Feng Gao Kaixian Chen Yu Zhou Hong Liu A traceless approach to quinolin-4(1H)-one scaffolds through Rh(III)-catalyzed redox-neutral [3+3] cyclization of N-nitrosoanilines with cyclopropenones has been achieved....
Molecules, Vol. 25, Pages 269: Recent Advance in Co3O4 and Co3O4-Containing Electrode Materials for High-Performance Supercapacitors Molecules doi: 10.3390/molecules25020269 Authors: Wang Hu Meng Wu Yang Hong Among the popular electrochemical energy storage devices, supercapacitors (SCs) have attracted much attention due to their long cycle life, fast charge and discharge, safety, and reliability. Transition metal oxides are one of the most widely used electrode...
Molecules, Vol. 25, Pages 271: The Underlying Mechanisms of Curcumin Inhibition of Hyperglycemia and Hyperlipidemia in Rats Fed a High-Fat Diet Combined With STZ Treatment Molecules doi: 10.3390/molecules25020271 Authors: Zhen-Hong Xia Wen-Bo Chen Li Shi Xue Jiang Ke Li Yu-Xiang Wang Yan-Qiang Liu Curcumin is the main secondary metabolite of Curcuma longa and other Curcuma spp, and has been reported to have some potential in preventing and treating some physiological...
Molecules, Vol. 25, Pages 265: Rationally Designed Ruthenium Complexes for Breast Cancer Therapy Molecules doi: 10.3390/molecules25020265 Authors: Golara Golbaghi Annie Castonguay Since the discovery of the anticancer potential of ruthenium-based complexes, several species were reported as promising candidates for the treatment of breast cancer, which accounts for the greatest number of new cases in women every year worldwide. Among these ruthenium complexes, species containing bioactive...
Molecules, Vol. 25, Pages 266: Design, Synthesis and In Vitro Characterization of Novel Antimicrobial Agents Based on 6-Chloro-9H-carbazol Derivatives and 1,3,4-Oxadiazole Scaffolds Molecules doi: 10.3390/molecules25020266 Authors: Alexandra T. Bordei Telehoiu Diana C. Nuță Miron T. Căproiu Florea Dumitrascu Irina Zarafu Petre Ioniță Carmellina D. Bădiceanu Speranța Avram Mariana C. Chifiriuc Coralia Bleotu Carmen Limban In this paper, we aimed to exploit...
Molecules, Vol. 25, Pages 264: Structure-Based Virtual Screening, Molecular Dynamics and Binding Free Energy Calculations of Hit Candidates as ALK-5 Inhibitors Molecules doi: 10.3390/molecules25020264 Authors: Sheila C. Araujo Vinicius G. Maltarollo Michell O. Almeida Leonardo L. G. Ferreira Adriano D. Andricopulo Kathia M. Honorio Activin-like kinase 5 (ALK-5) is involved in the physiopathology of several conditions, such as pancreatic carcinoma, cervical cancer and liver...
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Nanomaterials, Vol. 10, Pages 124: Visible-Light Active Titanium Dioxide Nanomaterials with Bactericidal Properties Nanomaterials doi: 10.3390/nano10010124 Authors: Liao Li Tjong This article provides an overview of current research into the development, synthesis, photocatalytic bacterial activity, biocompatibility and cytotoxic properties of various visible-light active titanium dioxide (TiO2) nanoparticles (NPs) and their nanocomposites. To achieve antibacterial inactivation...
Nanomaterials, Vol. 10, Pages 125: Sensitive Voltammetric Sensor for Tryptophan Detection by Using Polyvinylpyrrolidone Functionalized Graphene/GCE Nanomaterials doi: 10.3390/nano10010125 Authors: Quanguo He Jun Liu Jinxia Feng Yiyong Wu Yaling Tian Guangli Li Dongchu Chen In this paper, an electrochemical method for the measurement of tryptophan (Trp) was developed based on a glassy carbon electrode modified with polyvinylpyrrolidonefunctionalized graphene (PVP-GR)/glassy...
Nanomaterials, Vol. 10, Pages 123: Recent Advances in Organic Piezoelectric Biomaterials for Energy and Biomedical Applications Nanomaterials doi: 10.3390/nano10010123 Authors: Dong-Myeong Shin Suck Won Hong Yoon-Hwae Hwang The past decade has witnessed significant advances in medically implantable and wearable devices technologies as a promising personal healthcare platform. Organic piezoelectric biomaterials have attracted widespread attention as the functional materials in the...
Nanomaterials, Vol. 10, Pages 126: Anomalous Thermal Response of Graphene Kirigami Induced by Tailored Shape to Uniaxial Tensile Strain: A Molecular Dynamics Study Nanomaterials doi: 10.3390/nano10010126 Authors: Hui Li Gao Cheng Yongjian Liu Dan Zhong The mechanical and thermal properties of graphene kirigami are strongly dependent on the tailoring structures. Here, thermal conductivity of three typical graphene kirigami structures, including square kirigami graphene, reentrant...
Nanomaterials, Vol. 10, Pages 122: All-Plasmonic Switching Effect in the Graphene Nanostructures Containing Quantum Emitters Nanomaterials doi: 10.3390/nano10010122 Authors: Mikhail Yu. Gubin Andrey Yu. Leksin Alexander V. Shesterikov Alexei V. Prokhorov Valentyn S. Volkov Nonlinear plasmonic effects in perspective 2D materials containing low-dimensional quantum emitters can be a basis of a novel technological platform for the fabrication of fast all-plasmonic triggers, transistors,...
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Nutrients, Vol. 12, Pages 191: Effect of Cdx2 Polymorphism on the Relationship between Dietary Calcium Intake and Peak Bone Mass in Young Japanese Women Nutrients doi: 10.3390/nu12010191 Authors: Fumi Oono Yuri Sakamoto Yoichi Tachi Hideaki Mabashi-Asazuma Kaoruko Iida Studies investigating the effect of the caudal-type homeobox protein 2 (Cdx2) polymorphism in the vitamin D receptor gene and calcium intake on bone mass have shown inconsistent results. This study investigated...
Nutrients, Vol. 12, Pages 190: Next Steps for Interventions Targeting Adolescent Dietary Behaviour Nutrients doi: 10.3390/nu12010190 Authors: Evans Adolescents in many countries consume poor quality diets that include high intakes of sugary drinks and fast food and low intakes of vegetables. The aims of this Special Issue on adolescent dietary behaviour were to identify methods and approaches for successful interventions to improve diet quality in this age group and identify at risk...
Nutrients, Vol. 12, Pages 188: Does Acute Beetroot Juice Supplementation Improve Neuromuscular Performance and Match Activity in Young Basketball Players? A Randomized, Placebo-Controlled Study Nutrients doi: 10.3390/nu12010188 Authors: López-Samanes Gómez Parra Moreno-Pérez Courel-Ibáñez Whereas beetroot juice (BJ) supplementation is shown to increase physical performance in endurance activities, its benefits in team sports has been barely studied. In this randomized placebo-controlled...
Nutrients, Vol. 12, Pages 189: Association of Blood Mercury Level with the Risk of Depression According to Fish Intake Level in the General Korean Population: Findings from the Korean National Health and Nutrition Examination Survey (KNHANES) 2008–2013 Nutrients doi: 10.3390/nu12010189 Authors: Kim Sreeja Kwon Yu Kim Mercury is a cumulative neurotoxic agent, exposure to high levels of which may increase the risk of psychiatric symptoms. The purpose of this study was...
Nutrients, Vol. 12, Pages 186: Assessment of Malnutrition, Sarcopenia and Frailty in Patients with Cirrhosis: Which Tools Should We Use in Clinical Practice? Nutrients doi: 10.3390/nu12010186 Authors: Buchard Boirie Cassagnes Lamblin Coilly Abergel Malnutrition is a common comorbidity in patients with cirrhosis. Its prognostic value is indisputable as it greatly affects the evolution of liver diseases. It has a major impact on both morbi-mortality before and after...
Nutrients, Vol. 12, Pages 187: Short-Term Effect of One-Anastomosis Gastric Bypass on Essential Fatty Acids in the Serum of Obese Patients Nutrients doi: 10.3390/nu12010187 Authors: Mika Wilczynski Pakiet Kaska Proczko-Stepaniak Stankiewicz Stepnowski Sledzinski One-anastomosis gastric bypass is a promising type of bariatric surgery, but it may lead to a deficiency in important nutrients, such as fatty acids. The short-term effects of one-anastomosis gastric...
Nutrients, Vol. 12, Pages 185: Influence of Diabetes during Pregnancy on Human Milk Composition Nutrients doi: 10.3390/nu12010185 Authors: Chiara Peila Diego Gazzolo Enrico Bertino Francesco Cresi Alessandra Coscia Human milk (HM) is a unique nourishment believed to contain biological factors contributing to both short and long-term benefits. Considering that a mother’s own milk is often considered the first choice for nutrition of neonates, an aspect of increased...
Nutrients, Vol. 12, Pages 184: Attenuation of Weight Gain and Prevention of Associated Pathologies by Inhibiting SSAO Nutrients doi: 10.3390/nu12010184 Authors: Dimitri Papukashvili Nino Rcheulishvili Yulin Deng Obesity is a worldwide prevalent metabolic disorder that is associated with diabetes, among many other diseases. Bearing this in mind, prevention and treatment ways need to be improved. Notably, activity of the enzyme semicarbazide-sensitive amine oxidase (SSAO) is found...
Nutrients, Vol. 12, Pages 183: Physical Activity in Eating Disorders: A Systematic Review Nutrients doi: 10.3390/nu12010183 Authors: Melissa Lama Laurence Sylvie Jeanne Odile Nathalie Abnormally high levels of physical activity have been documented throughout the literature in patients with eating disorders (ED), especially those diagnosed with anorexia nervosa (AN). Yet no clear definition, conceptualization, or treatment of the problematic use of physical activity...
Nutrients, Vol. 12, Pages 182: The Effect of Donor Human Milk Fortification on The Adhesion of Probiotics In Vitro Nutrients doi: 10.3390/nu12010182 Authors: Anastasia Mantziari Satu Tölkkö Artur C. Ouwehand Eliisa Löyttyniemi Erika Isolauri Seppo Salminen Samuli Rautava Preterm delivery complications are the primary cause of death among children under the age of five. Preventive strategies include the use of pasteurized donor human milk (DHM), its fortification with...
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Pathogens, Vol. 9, Pages 50: Genotypic Comparison between Streptococcus suis Isolated from Pigs and Humans in Thailand Pathogens doi: 10.3390/pathogens9010050 Authors: Anusak Kerdsin Dan Takeuchi Aniroot Nuangmek Yukihiro Akeda Marcelo Gottschalk Kazunori Oishi Streptococcus suis is a zoonotic pathogen of economic significance to the swine industry. The number of infected cases is increasing in humans worldwide. In this study, we determined the prevalence and diversity...
Pathogens, Vol. 9, Pages 49: Antileishmanial Activity and Synergistic Effects of Amphotericin B Deoxycholate with Allicin and Andrographolide against Leishmania martiniquensis In Vitro Pathogens doi: 10.3390/pathogens9010049 Authors: Nuchpicha Intakhan Wetpisit Chanmol Pradya Somboon Michelle D. Bates Vanessa Yardley Paul A. Bates Narissara Jariyapan Leishmania (Mundinia) martiniquensis is a causative agent of visceral leishmaniasis, but in HIV-infected patients both...
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Pharmaceutics, Vol. 12, Pages 57: Special Issue on Designing Hydrogels for Controlled Drug Delivery: Guest Editors’ Introduction Pharmaceutics doi: 10.3390/pharmaceutics12010057 Authors: Sonia Trombino Roberta Cassano Hydrogels have received growing attention in recent years as materials for drug delivery systems (DDS), because they are biocompatible and nontoxic [...]
Pharmaceutics, Vol. 12, Pages 54: Novel Population Pharmacokinetic Model for Linezolid in Critically Ill Patients and Evaluation of the Adequacy of the Current Dosing Recommendation Pharmaceutics doi: 10.3390/pharmaceutics12010054 Authors: Soraluce Barrasa Asín-Prieto Sánchez-Izquierdo Maynar Isla Rodríguez-Gascón Antimicrobial treatment in critically ill patients remains challenging. The aim of this study was to develop a population pharmacokinetic model for...
Pharmaceutics, Vol. 12, Pages 55: Influence of Composition and Spray-Drying Process Parameters on Carrier-Free DPI Properties and Behaviors in the Lung: A review Pharmaceutics doi: 10.3390/pharmaceutics12010055 Authors: Lechanteur Evrard Although dry powder inhalers (DPIs) have attracted great interest compared to nebulizers and metered-dose inhalers (MDIs), drug deposition in the deep lung is still insufficient to enhance therapeutic activity. Indeed, it is estimated that only...
Pharmaceutics, Vol. 12, Pages 53: Insight into the Formation of Glimepiride Nanocrystals by Wet Media Milling Pharmaceutics doi: 10.3390/pharmaceutics12010053 Authors: Medarević Ibrić Vardaka Mitrić Nikolakakis Kachrimanis Nanocrystal formation for the dissolution enhancement of glimepiride was attempted by wet media milling. Different stabilizers were tested and the obtained nanosuspensions were solidified by spray drying in presence of mannitol, and characterized...
Pharmaceutics, Vol. 12, Pages 56: Development of Bio-Active Patches Based on Pectin for the Treatment of Ulcers and Wounds Using 3D-Bioprinting Technology Pharmaceutics doi: 10.3390/pharmaceutics12010056 Authors: Andriotis Eleftheriadis Karavasili Fatouros Biodegradable 3D-printable inks based on pectin have been developed as a system for direct and indirect wound-dressing applications, suitable for 3D printing technologies. The 3D-printable inks formed free-standing transparent...
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Pharmacy, Vol. 8, Pages 7: The Impact of Pharmacist Vaccination Privilege during a Nation-Wide Measles Outbreak Pharmacy doi: 10.3390/pharmacy8010007 Authors: Singh Smith-Ray Taitel The 2019 measles outbreak was the worst since the US eliminated measles in 2000. This paper presents the vaccination trends for a large chain-pharmacy, Walgreens, and examines the estimated vaccination capacity and impact of pharmacist privilege policies across states. Specifically, we estimated...
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Plants, Vol. 9, Pages 85: Study of Ecophysiological Responses of the Antarctic Fruticose Lichen Cladonia borealis Using the PAM Fluorescence System under Natural and Laboratory Conditions Plants doi: 10.3390/plants9010085 Authors: Cho Lee Hong Lee Antarctic lichens have been used as indicators of climate change for decades, but only a few species have been studied. We assessed the photosynthetic performance of the fruticose lichen Cladonia borealis under natural and laboratory...
Plants, Vol. 9, Pages 86: Water Deficit Transcriptomic Responses Differ in the Invasive Tamarix chinensis and T. ramosissima Established in the Southern and Northern United States Plants doi: 10.3390/plants9010086 Authors: Swaminathan Ohrtman Carinder Deuja Wang Gaskin Fennell Clay Tamarix spp. (saltcedar) were introduced from Asia to the southern United States as windbreak and ornamental plants and have spread into natural areas. This study determined differential...
Plants, Vol. 9, Pages 84: Effects of Arbuscular Mycorrhizal Fungi on Yield, Biochemical Characteristics, and Elemental Composition of Garlic and Onion under Selenium Supply Plants doi: 10.3390/plants9010084 Authors: Nadezhda Golubkina Zarema Amagova Visita Matsadze Svetlana Zamana Alessio Tallarita Gianluca Caruso Biofortification of garlic and onion plants with selenium and arbuscular mycorrhizal fungi inoculation are considered beneficial for producing functional food...
Plants, Vol. 9, Pages 83: Temperature and Light-Quality-Dependent Regulation of Freezing Tolerance in Barley Plants doi: 10.3390/plants9010083 Authors: Mohamed Ahres Krisztián Gierczik Ákos Boldizsár Pavel Vítámvás Gábor Galiba It is established that, besides the cold, incident light also has a crucial role in the cold acclimation process. To elucidate the interaction between these two external hardening factors, barley plantlets were grown under different light conditions...
Plants, Vol. 9, Pages 82: Assessment of Local and Systemic Changes in Plant Gene Expression and Aphid Responses during Potato Interactions with Arbuscular Mycorrhizal Fungi and Potato Aphids Plants doi: 10.3390/plants9010082 Authors: Eric Rizzo Tyler Sherman Patricia Manosalva S. Karen Gomez This research examined aphid and plant responses to distinct levels (none, low, and high) of arbuscular mycorrhizal (AM) fungal root colonization by studying the association between potato...
Plants, Vol. 9, Pages 81: Leaf Gas Exchange Performance of Ten Quinoa Genotypes under a Simulated Heat Wave Plants doi: 10.3390/plants9010081 Authors: Ashley Eustis Kevin M. Murphy Felipe H. Barrios-Masias Quinoa (Chenopodium quinoa Willd.) is a highly nutritious crop that is resilient to a wide range of abiotic stresses; however, sensitivity to high temperatures is regarded as an impediment to adoption in regions prone to heat waves. Heat stress is usually associated with a decrease...
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Psych, Vol. 2, Pages 44-51: Differential Item Functioning on Raven’s SPM+ Amongst Two Convenience Samples of Yakuts and Russians Psych doi: 10.3390/psych2010005 Authors: Vladimir Shibaev Andrei Grigoriev Ekaterina Valueva Anatoly Karlin National IQ estimates are based on psychometric measurements carried out in a variety of cultural contexts and are often obtained from Raven’s Progressive Matrices tests. In a series of studies, J. Philippe Rushton et al. have argued...
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Religions, Vol. 11, Pages 37: Association between Religion and Health in China: Using Propensity Score Matching Method Religions doi: 10.3390/rel11010037 Authors: Jing Hua Zhang Haomin Zhang Chengkun Liu Xiaoyang Jiang Hongmin Zhang Ojo Iwaloye The association between religion and health is well debated and receives continuous attention in research. Selection bias is often a major concern among the observatory data routinely used worldwide to examine this topic. Adopting...
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Sci, Vol. 2, Pages 2: Mechanical Energy before Chemical Energy at the Origins of Life? Sci doi: 10.3390/sci2010002 Authors: Hansma Mechanical forces and mechanical energy are prevalent in living cells. This may be because mechanical forces and mechanical energy preceded chemical energy at life’s origins. Mechanical energy is more readily available in non-living systems than the various forms of chemical energy used by living systems. Two possible prebiotic environments that...
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Sports, Vol. 8, Pages 6: Assessing the Wider Implementation of the SHARP Principles: Increasing Physical Activity in Primary Physical Education Sports doi: 10.3390/sports8010006 Authors: Emma Powell Lorayne Angela Woodfield Alexander James Powell Alan Michael Nevill To assess the wider application of the SHARP (Stretching whilst moving, High repetition of skills, Accessibility, Reducing sitting and standing, and Promotion of physical activity) Principles intervention on children’s...
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Toxins, Vol. 12, Pages 41: Aberrant Expressional Profiling of Known MicroRNAs in the Liver of Silver Carp (Hypophthalmichthys molitrix) Following Microcystin-LR Exposure Based on samllRNA Sequencing Toxins doi: 10.3390/toxins12010041 Authors: Yiyi Feng Xi Chen Junguo Ma Bangjun Zhang Xiaoyu Li Microcystin-LR (MC-LR) poses a serious threat to human health due to its hepatotoxicity. However, the specific molecular mechanism of miRNAs in MC-LR-induced liver injury has not been...
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Vaccines, Vol. 8, Pages 18: Alpha-Gal and Cross-Reactive Carbohydrate Determinants in the N-Glycans of Salivary Glands in the Lone Star Tick, Amblyomma americanum Vaccines doi: 10.3390/vaccines8010018 Authors: Yoonseong Park Donghun Kim Gunavanthi D. Boorgula Kristof De Schutter Guy Smagghe Ladislav Šimo Stephanie A. Archer-Hartmann Parastoo Azadi Ticks are important ectoparasites and vectors of numerous human and animal pathogens. Ticks secrete saliva that contains...
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Viruses, Vol. 12, Pages 82: Infection of Human Tracheal Epithelial Cells by H5 Avian Influenza Virus Is Regulated by the Acid Stability of Hemagglutinin and the pH of Target Cell Endosomes Viruses doi: 10.3390/v12010082 Authors: Daidoji Kajikawa Arai Watanabe Hirose Nakaya Despite the possible relationships between tracheal infection and concomitant infection of the terminal part of the lower respiratory tract (bronchioles/alveoli), the behavior of avian influenza...
Viruses, Vol. 12, Pages 81: Risks and Challenges of Arboviral Diseases in Sudan: The Urgent Need for Actions Viruses doi: 10.3390/v12010081 Authors: Ahmed Dietrich LaBeaud Lindsay Musa Weaver The risk of emergence and/or re-emergence of arthropod-borne viral (arboviral) infections is rapidly growing worldwide, particularly in Africa. The burden of arboviral infections and diseases is not well scrutinized because of the inefficient surveillance systems in endemic...
Viruses, Vol. 12, Pages 80: Fetal Calf Serum Exerts an Inhibitory Effect on Replication of Duck Hepatitis A Virus Genotype 1 in Duck Embryo Fibroblast Cells Viruses doi: 10.3390/v12010080 Authors: Minghang Wang Lili Chai Suyun Liang Junfeng Lv Lixin Yang Shenghua Qu Meiling Jin Qingxiangzi Li Xiaoyan Wang Dabing Zhang Among the causative agents of duck viral hepatitis, duck hepatitis A virus genotype 1 (DHAV-1) is the most common virus reported in most outbreaks...
Viruses, Vol. 12, Pages 79: Isolation and Identification of Porcine Deltacoronavirus and Alteration of Immunoglobulin Transport Receptors in the Intestinal Mucosa of PDCoV-Infected Piglets Viruses doi: 10.3390/v12010079 Authors: Shaoju Qian Xiangchao Jia Zitong Gao Weida Zhang Qingrong Xu Zili Li Porcine deltacoronavirus (PDCoV) is a porcine enteropathogenic coronavirus that causes watery diarrhea, vomiting, and frequently death in piglets, causing serious economic losses...
Viruses, Vol. 12, Pages 78: Antibody Responses against Enterovirus Proteases are Potential Markers for an Acute Infection Viruses doi: 10.3390/v12010078 Authors: Niila V. V. Saarinen Virginia M. Stone Minna M. Hankaniemi Magdalena A. Mazur Tytti Vuorinen Malin Flodström-Tullberg Heikki Hyöty Vesa P. Hytönen Olli H. Laitinen Background: Enteroviruses are a group of common non-enveloped RNA viruses that cause symptoms ranging from mild respiratory infections to...
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Water, Vol. 12, Pages 191: A Comparison of Streamflow and Baseflow Responses to Land-Use Change and the Variation in Climate Parameters Using SWAT Water doi: 10.3390/w12010191 Authors: Mohamed Aboelnour Margaret W. Gitau Bernard A. Engel Alteration of land use and climate change are among the main variables affecting watershed hydrology. Characterizing the impacts of climate variation and land use alteration on water resources is essential in managing watersheds. Thus, in this...
Water, Vol. 12, Pages 192: Evidence of Natural and Anthropogenic Impacts on Rainwater Trace Metal Geochemistry in Central Mexico: A Statistical Approach Water doi: 10.3390/w12010192 Authors: D. M. Rivera-Rivera D. C. Escobedo-Urías M. P. Jonathan S. B. Sujitha S. Chidambaram Trace metals Fe, Mn, Cr, Cu, Ni, Co, Pb, Zn, Cd, and As were determined on a monthly basis in a total of 52 rain samples collected from six different locations in the central region of Mexico during March...
Water, Vol. 12, Pages 190: Spatial and Temporal Variability of Water Quality in the Bystrzyca River Basin, Poland Water doi: 10.3390/w12010190 Authors: Grzywna Bronowicka-Mielniczuk . The aim of the study was to analyze the results of surface water quality tests carried out in the Bystrzyca river basin. The study was conducted over four years in four seasons. The following chemometric techniques were used for the purposes of statistical analyses: the principal component analysis...
Water, Vol. 12, Pages 188: Performance of an Array of Oblate Spheroidal Heaving Wave Energy Converters in Front of a Wall Water doi: 10.3390/w12010188 Authors: Eva Loukogeorgaki Ifigeneia Boufidi Ioannis K. Chatjigeorgiou In this paper, we investigate the performance of a linear array of five semi-immersed, oblate spheroidal heaving Wave Energy Converters (WECs) in front of a bottom-mounted, finite-length, vertical wall under perpendicular to the wall regular waves. The diffraction...
Water, Vol. 12, Pages 187: Resilient Urban Water Services for the 21th Century Society—Stakeholder Survey in Finland Water doi: 10.3390/w12010187 Authors: Jyrki Laitinen Johanna Kallio Tapio S. Katko Jarmo J. Hukka Petri Juuti Resilience has become a vital theme in the discussion concerning urban water services. Resilience in this context can be defined as both keeping up a good level of services, as well as rapid and fluent recovery from failures caused by natural disasters,...
Water, Vol. 12, Pages 189: Modelling Impacts of a Municipal Spatial Plan of Land-Use Changes on Surface Water Quality—Example from Goriška Brda in Slovenia Water doi: 10.3390/w12010189 Authors: Glavan Bele Curk Pintar Intensive agriculture causes nutrient leaching and accelerates erosion processes, which threatens the good quality status of surface waters, as proposed by the European Union (EU) Water Framework Directive. The purpose of this study was to define the impact...
Water, Vol. 12, Pages 185: A Clustered, Decentralized Approach to Urban Water Management Water doi: 10.3390/w12010185 Authors: Seneshaw Tsegaye Thomas M. Missimer Jong-Yeop Kim Jason Hock Current models in design of urban water management systems and their corresponding infrastructure using centralized designs have commonly failed from the perspective of cost effectiveness and inability to adapt to the future changes. These challenges are driving cities towards using decentralized...
Water, Vol. 12, Pages 184: Characterization of Kyagar Glacier and Lake Outburst Floods in 2018 Based on Time-Series Sentinel-1A Data Water doi: 10.3390/w12010184 Authors: Meimei Zhang Fang Chen Bangsen Tian Dong Liang Aqiang Yang Early recognition of glacial lake outburst floods (GLOFs) is required for timely and cost-effective remedial efforts to be implemented. Although the formation of ice-dammed lakes is known to begin as a pond or river that was blocked by ice from the...
Water, Vol. 12, Pages 186: Hydrodynamic Structure with Scour Hole Downstream of Bed Sills Water doi: 10.3390/w12010186 Authors: Ben Meftah De Serio De Padova Mossa Experimental turbulence measurements of scour hole downstream of bed sills in alluvial channels with non-cohesive sediments are investigated. Using an Acoustic Doppler Velocimeter (ADV), the flow velocity-field within the equilibrium scour hole was comprehensively measured. In this study, we especially focus on...
Water, Vol. 12, Pages 183: 2-D Characteristics of Wave Deformation Due to Wave-Current Interactions with Density Currents in an Estuary Water doi: 10.3390/w12010183 Authors: Woo-Dong Lee Norimi Mizutani Dong-Soo Hur In this study, numerical simulations were conducted in order to understand the role of wave-current interactions in wave deformation. The wave-current interaction mechanisms, wave reflection and energy loss due to currents, the effect of incident conditions on wave-current...
Water, Vol. 12, Pages 182: Small and Medium-Scale River Flood Controls in Highly Urbanized Areas: A Whole Region Perspective Water doi: 10.3390/w12010182 Authors: Zengmei Liu Yuting Cai Shangwei Wang Fupeng Lan Xushu Wu While rapid urbanization promotes social and economic development, it poses a serious threat to the health of rivers, especially the small and medium-scale rivers. Flood control for small and medium-scale rivers in highly urbanized areas is particularly important....
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