Antibiotics, Vol. 9, Pages 60: Predicting Antimicrobial and Other Cysteine-Rich Peptides in 1267 Plant Transcriptomes Antibiotics doi: 10.3390/antibiotics9020060 Authors: Andrey Shelenkov Anna Slavokhotova Tatyana Odintsova Antimicrobial peptides (AMPs) are a key component of innate immunity in various organisms including bacteria, insects, mammals, and plants. Their mode of action decreases the probability of developing resistance in pathogenic organisms, which makes them a promising...
Antibiotics, Vol. 9, Pages 59: Bacterial Biofilm and its Role in the Pathogenesis of Disease Antibiotics doi: 10.3390/antibiotics9020059 Authors: Vestby Grønseth Simm Nesse Recognition of the fact that bacterial biofilm may play a role in the pathogenesis of disease has led to an increased focus on identifying diseases that may be biofilm-related. Biofilm infections are typically chronic in nature, as biofilm-residing bacteria can be resilient to both the immune system,...
Antibiotics, Vol. 9, Pages 58: Ceftazidime/Avibactam and Ceftolozane/Tazobactam for Multidrug-Resistant Gram Negatives in Patients with Hematological Malignancies: Current Experiences Antibiotics doi: 10.3390/antibiotics9020058 Authors: Marianna Criscuolo Enrico Maria Trecarichi Patients suffering from hematological malignancies are at high risk for severe infections, including in particular bloodstream infections, which represent one of the most frequent life-threatening complications...
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Antioxidants, Vol. 9, Pages 130: Healing Properties of Epidermal Growth Factor and Tocotrienol-Rich Fraction in Deep Partial-Thickness Experimental Burn Wounds Antioxidants doi: 10.3390/antiox9020130 Authors: Hui-fang Guo Roslida Abd Hamid Razana Mohd Ali Sui Kiat Chang Mohammed Habibur Rahman Zaida Zainal Huzwah Khaza’ai Background: An experimental study was undertaken to determine the efficacy of the epidermal growth factor (EGF) with tocotrienol-rich fraction (TRF)...
Antioxidants, Vol. 9, Pages 133: Polyurea Dendrimer Folate-Targeted Nanodelivery of l-Buthionine sulfoximine as a Tool to Tackle Ovarian Cancer Chemoresistance Antioxidants doi: 10.3390/antiox9020133 Authors: Cruz Mota Ramos Pires Mendes Silva Nunes Bonifácio Serpa : Ovarian cancer is a highly lethal disease, mainly due to chemoresistance. Our previous studies on metabolic remodeling in ovarian cancer have supported that the reliance on glutathione (GSH)...
Antioxidants, Vol. 9, Pages 132: Antioxidant Effect of Cocoa By-Product and Cherry Polyphenol Extracts: A Comparative Study Antioxidants doi: 10.3390/antiox9020132 Authors: Francesca Felice Angela Fabiano Marinella De Leo Anna Maria Piras Denise Beconcini Maria Michela Cesare Alessandra Braca Ylenia Zambito Rossella Di Stefano Background: Recent studies have highlighted the importance of cherry and cocoa extracts consumption to protect cells from oxidative stress,...
Antioxidants, Vol. 9, Pages 131: Phenolic Fractions from Dandelion Leaves and Petals as Modulators of the Antioxidant Status and Lipid Profile in an In Vivo Study Antioxidants doi: 10.3390/antiox9020131 Authors: Michał Majewski Bernadetta Lis Jerzy Juśkiewicz Katarzyna Ognik Małgorzata Borkowska-Sztachańska Dariusz Jedrejek Anna Stochmal Beata Olas Alcoholic leaf and petal fractions of Taraxacum officinale (dandelion) were previously demonstrated to exert in vitro...
Antioxidants, Vol. 9, Pages 129: Visualization of the Redox Status of Cytosolic Glutathione Using the Organelle- and Cytoskeleton-Targeted Redox Sensors Antioxidants doi: 10.3390/antiox9020129 Authors: Yuta Hatori Takanori Kubo Yuichiro Sato Sachiye Inouye Reiko Akagi Toshio Seyama Glutathione is a small thiol-containing peptide that plays a central role in maintaining cellular redox homeostasis. Glutathione serves as a physiologic redox buffer by providing thiol electrons...
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Atmosphere, Vol. 11, Pages 159: Statistical Modelling of Temperature-Attributable Deaths in Portuguese Metropolitan Areas under Climate Change: Who Is at Risk? Atmosphere doi: 10.3390/atmos11020159 Authors: Mónica Rodrigues Paula Santana Alfredo Rocha Several studies emphasize that temperature-related mortality can be expected to have differential effects on different subpopulations, particularly in the context of climate change. This study aims to evaluate and quantify the future...
Atmosphere, Vol. 11, Pages 158: An Observational Study of the Symmetric Boundary Layer Structure and Tropical Cyclone Intensity Atmosphere doi: 10.3390/atmos11020158 Authors: Ren Zhang Vigh Zhu Liu Wang Wadler This study analyses Global Positioning System dropsondes to document the axisymmetric tropical cyclone (TC) boundary-layer structure, based on storm intensity. A total of 2608 dropsondes from 42 named TCs in the Atlantic basin from 1998 to 2017 are used...
Atmosphere, Vol. 11, Pages 157: Temporal and Cross-Regional Variability in the Level of Air Pollution in Poland—A Study Using Moss as a Bioindicator Atmosphere doi: 10.3390/atmos11020157 Authors: Paweł Kapusta Barbara Godzik This study assessed recent (2015) and past (2001) levels of air pollution in four regions of Poland by moss monitoring. The surveyed regions encompassed, among others, copper and zinc-lead industrial districts, large urban agglomerations and an area away from...
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Behavioral Sciences, Vol. 10, Pages 49: Children’s Creativity and Personal Adaptation Resources Behavioral Sciences doi: 10.3390/bs10020049 Authors: Vera G. Gryazeva-Dobshinskaya Yulia A. Dmitrieva Svetlana Yu. Korobova Vera A. Glukhova The study provides insights into the aspects of creativity, the structure of psychometric intelligence, and personal adaptation resources of senior preschool children. Creativity and intelligence are presented as general adaptation resources....
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Biology, Vol. 9, Pages 25: “What You Need, Baby, I Got It”: Transposable Elements as Suppliers of Cis-Operating Sequences in Drosophila Biology doi: 10.3390/biology9020025 Authors: Moschetti Palazzo Lorusso Viggiano Marsano Transposable elements (TEs) are constitutive components of both eukaryotic and prokaryotic genomes. The role of TEs in the evolution of genes and genomes has been widely assessed over the past years in a variety of model and non-model organisms. Drosophila...
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Biomedicines, Vol. 8, Pages 23: Short-Term Diet Restriction but Not Alternate Day Fasting Prevents Cisplatin-Induced Nephrotoxicity in Mice Biomedicines doi: 10.3390/biomedicines8020023 Authors: Gunebakan Yalcin Dulger Yigitbasi Ates Caglayan Beker Sahin Korkaya Kilic Cisplatin (CP) is one of the most preferred platinum-containing antineoplastic drugs. However, even in nontoxic plasma concentrations, it may cause kidney injury. To be able to increase...
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Biomimetics, Vol. 5, Pages 5: Orientation-Dependent Reflection of Structurally Coloured Butterflies Biomimetics doi: 10.3390/biomimetics5010005 Authors: Zobl Wilts Salvenmoser Pölt Gebeshuber Schwerte Keywords: orientation-dependent reflection; structural color; butterflies; imprinting technique; instrument adaptation
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Biomolecules, Vol. 10, Pages 223: Oral HPV16 Prevalence in Oral Potentially Malignant Disorders and Oral Cavity Cancers Biomolecules doi: 10.3390/biom10020223 Authors: Tang Menezes Baeten Walsh Whitfield Batstone Kenny Frazer Scheper Punyadeera The role of human papillomavirus type 16 (HPV16) in oral potentially malignant disorders (OPMD) and oral cavity carcinoma (OC) is still under debate. We investigated HPV16 prevalence in unstimulated saliva,...
Biomolecules, Vol. 10, Pages 225: Testosterone and Adult Neurogenesis Biomolecules doi: 10.3390/biom10020225 Authors: Spritzer Roy It is now well established that neurogenesis occurs throughout adulthood in select brain regions, but the functional significance of adult neurogenesis remains unclear. There is considerable evidence that steroid hormones modulate various stages of adult neurogenesis, and this review provides a focused summary of the effects of testosterone on adult...
Biomolecules, Vol. 10, Pages 224: Metabolic and Proteomic Perspectives of Augmentation of Nutritional Contents and Plant Defense in Vigna unguiculata Biomolecules doi: 10.3390/biom10020224 Authors: Ahmad Khan Mubeen Shahzadi Akram Saeed Bashir Wang Alam Ahmed Hu Li Wu The current study enlists metabolites of Alstonia scholaris with bioactivities, and the most active compound, 3-(1-methylpyrrolidin-2-yl) pyridine, was selected against...
Biomolecules, Vol. 10, Pages 226: Different Effects of Nicotine and N-Stearoyl-ethanolamine on Episodic Memory and Brain Mitochondria of α7 Nicotinic Acetylcholine Receptor Knockout Mice Biomolecules doi: 10.3390/biom10020226 Authors: Lykhmus Kalashnyk Uspenska Horid’ko Kosyakova Komisarenko Skok Nicotinic acetylcholine receptors of α7 subtype (α7 nAChRs) are involved in regulating neuroinflammation and cognitive functions. Correspondingly,...
Biomolecules, Vol. 10, Pages 222: CLytA-DAAO, Free and Immobilized in Magnetic Nanoparticles, induces Cell Death in Human Cancer Cells Biomolecules doi: 10.3390/biom10020222 Authors: Fuentes-Baile Bello-Gil Pérez-Valenciano Sanz García-Morales Maestro Ventero Alenda Barberá Saceda D-amino acid oxidase (DAAO) catalyzes the oxidation of D-amino acids generating hydrogen peroxide, a potential producer of reactive oxygen species. In this study, we used...
Biomolecules, Vol. 10, Pages 221: Therapeutic Potential of Plant Phenolic Acids in the Treatment of Cancer Biomolecules doi: 10.3390/biom10020221 Authors: Abotaleb Liskova Kubatka Büsselberg Globally, cancer is the second leading cause of death. Different conventional approaches to treat cancer include chemotherapy or radiotherapy. However, these are usually associated with various deleterious effects and numerous disadvantages in clinical practice. In addition, there are...
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Cancers, Vol. 12, Pages 342: Comment on “Tumor-Associated Macrophages Induce Migration of Renal Cell Carcinoma Cells via Activation of the CCL20-CCR6 Axis” Cancers doi: 10.3390/cancers12020342 Authors: Zins Abraham Macrophages form a major component of the leukocyte infiltrate in solid tumors and it has become increasingly clear that tumor-associated macrophages (TAMs) have tumor-promoting effects within the stroma [1]. Renal cell carcinoma (RCC) solid tumors are comprised of a...
Cancers, Vol. 12, Pages 343: Comment on “Fibroblasts in Nodular Sclerosing Classical Hodgkin Lymphoma Are Defined by a Specific Phenotype and Protect Tumor Cells from Brentuximab-Vedotin Induced Injury” Cancers 2019, 11, 1687 Cancers doi: 10.3390/cancers12020343 Authors: Aldinucci Colombatti We read with great interest the recent publication by Bankov et al. where they described the characteristics and functional activity of fibroblasts in Nodular Sclerosis (NS) Classical Hodgkin...
Cancers, Vol. 12, Pages 341: Novel MicroRNA Biomarkers for Colorectal Cancer Early Diagnosis and 5-Fluorouracil Chemotherapy Resistance but Not Prognosis: A Study from Databases to AI-Assisted Verifications Cancers doi: 10.3390/cancers12020341 Authors: Zhang Zhang Shen Sun Colorectal cancer (CRC) is one of the major causes of cancer death worldwide. In general, early diagnosis for CRC and individual therapy have led to better survival for the cancer patients. Accumulating...
Cancers, Vol. 12, Pages 339: TGF-Beta-Activated Cancer-Associated Fibroblasts Limit Cetuximab Efficacy in Preclinical Models of Head and Neck Cancer Cancers doi: 10.3390/cancers12020339 Authors: Ksenia M. Yegodayev Ofra Novoplansky Artemiy Golden Manu Prasad Liron Levin Sankar Jagadeeshan Jonathan Zorea Orr Dimitstein Ben-Zion Joshua Limor Cohen Ekaterina Khrameeva Moshe Elkabets Most head and neck cancer (HNC) patients are resistant to cetuximab, an...
Cancers, Vol. 12, Pages 340: MicroRNAs as Theranostics Targets in Oral Carcinoma Stem Cells Cancers doi: 10.3390/cancers12020340 Authors: Pei-Ling Hsieh Yi-Wen Liao Martin Pichler Cheng-Chia Yu Oral cancer belongs to head and neck squamous cell carcinoma and has been recognized as one of the most prevalent malignancies worldwide. Recent studies have suggested that cancer stem cells (CSCs) may participate in tumor initiation, metastasis and even recurrence, so the regulation...
Cancers, Vol. 12, Pages 338: Oncology Clinic-Based Hereditary Cancer Genetic Testing in a Population-Based Health Care System Cancers doi: 10.3390/cancers12020338 Authors: Richardson Min Hong Compton Mung Lohn Nuk McCullum Portigal-Todd Karsan Regier Brotto Sun Schrader New streamlined models for genetic counseling and genetic testing have recently been developed in response to increasing demand for cancer genetic services. To improve...
Cancers, Vol. 12, Pages 337: Combination of Decitabine and Entinostat Synergistically Inhibits Urothelial Bladder Cancer Cells via Activation of FoxO1 Cancers doi: 10.3390/cancers12020337 Authors: Chenyin Wang Alexandra Hamacher Patrick Petzsch Karl Köhrer Günter Niegisch Michèle J. Hoffmann Wolfgang A. Schulz Matthias U. Kassack Occurrence of cisplatin-resistance in bladder cancer is frequent and results in disease progression. Thus, novel therapeutic approaches...
Cancers, Vol. 12, Pages 334: TDP1 and TOP1 Modulation in Olaparib-Resistant Cancer Determines the Efficacy of Subsequent Chemotherapy Cancers doi: 10.3390/cancers12020334 Authors: Jin Won Kim Ahrum Min Seock-Ah Im Hyemin Jang Yu Jin Kim Hee-Jun Kim Kyung-Hun Lee Tae-Yong Kim Keun Wook Lee Do-Youn Oh Jee-Hyun Kim Yung-Jue Bang The aim of this study was to elucidate the carryover effect of olaparib to subsequent chemotherapy and its underlying mechanisms....
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Cells, Vol. 9, Pages 356: A-Kinase Anchoring Proteins Diminish TGF-β1/Cigarette Smoke-Induced Epithelial-To-Mesenchymal Transition Cells doi: 10.3390/cells9020356 Authors: Zuo Trombetta-Lima Heijink van der Veen Hesse Faber Poppinga Maarsingh Nikolaev Schmidt Epithelial-to-mesenchymal transition (EMT) plays a role in chronic obstructive pulmonary diseases (COPD). Cyclic adenosine monophosphate (cAMP) can inhibit transforming growth factor-β1...
Cells, Vol. 9, Pages 353: PVPred-SCM: Improved Prediction and Analysis of Phage Virion Proteins Using a Scoring Card Method Cells doi: 10.3390/cells9020353 Authors: Charoenkwan Kanthawong Schaduangrat Yana Shoombuatong Although, existing methods have been successful in predicting phage (or bacteriophage) virion proteins (PVPs) using various types of protein features and complex classifiers, such as support vector machine and naïve Bayes, these two methods do...
Cells, Vol. 9, Pages 354: The miR-28-5p Targetome Discovery Identified SREBF2 as One of the Mediators of the miR-28-5p Tumor Suppressor Activity in Prostate Cancer Cells Cells doi: 10.3390/cells9020354 Authors: Fazio Berti Russo Evangelista D’Aurizio Mercatanti Pellegrini Rizzo miR-28-5p is downregulated in some tumor tissues in which it has been demonstrated to have tumor suppressor (TS) activity. Here, we demonstrate that miR-28-5p acts as a TS in prostate...
Cells, Vol. 9, Pages 350: Granulins Regulate Aging Kinetics in the Adult Zebrafish Telencephalon Cells doi: 10.3390/cells9020350 Authors: Zambusi Pelin Burhan Di Giaimo Schmid Ninkovic Granulins (GRN) are secreted factors that promote neuronal survival and regulate inflammation in various pathological conditions. However, their roles in physiological conditions in the brain remain poorly understood. To address this knowledge gap, we analysed the telencephalon in Grn-deficient...
Cells, Vol. 9, Pages 349: Curcumin Derivative GT863 Inhibits Amyloid-Beta Production via Inhibition of Protein N-Glycosylation Cells doi: 10.3390/cells9020349 Authors: Urano Takahachi Higashiura Fujiwara Funamoto Imai Futai Okuda Sugimoto Noguchi Amyloid-β (Aβ) peptides play a crucial role in the pathogenesis of Alzheimer’s disease (AD). Aβ production, aggregation, and clearance are thought to be important therapeutic...
Cells, Vol. 9, Pages 355: Impaired Nuclear Export of the Ribonucleoprotein Complex and Virus-Induced Cytotoxicity Combine to Restrict Propagation of the A/Duck/Malaysia/02/2001 (H9N2) Virus in Human Airway Cells Cells doi: 10.3390/cells9020355 Authors: Sriram Kumar Dawn Yeo Nisha Harur Muralidharan Soak Kuan Lai Cathlyn Tong Boon Huan Tan Richard J. Sugrue In humans, (A549) cells impaired H9N2 virus nuclear export of the ribonucleoprotein (RNP) complex contrasted with...
Cells, Vol. 9, Pages 351: A20 Promotes Ripoptosome Formation and TNF-Induced Apoptosis via cIAPs Regulation and NIK Stabilization in Keratinocytes Cells doi: 10.3390/cells9020351 Authors: Feoktistova Makarov Brenji Schneider Hooiveld Luedde Leverkus Yazdi Panayotova-Dimitrova The ubiquitin-editing protein A20 (TNFAIP3) is a known key player in the regulation of immune responses in many organs. Genome-wide associated studies (GWASs) have linked A20 with...
Cells, Vol. 9, Pages 352: PPAR-Mediated Toxicology and Applied Pharmacology Cells doi: 10.3390/cells9020352 Authors: Xi Zhang Zhu Luo Xu Huang Peroxisome proliferator-activated receptors (PPARs), members of the nuclear hormone receptor family, attract wide attention as promising therapeutic targets for the treatment of multiple diseases, and their target selective ligands were also intensively developed for pharmacological agents such as the approved drugs fibrates...
Cells, Vol. 9, Pages 348: Regulation of MT1-MMP Activity through Its Association with ERMs Cells doi: 10.3390/cells9020348 Authors: Suárez López-Martín Toribio Zamai Hernández-Riquer Genís Arroyo Yáñez-Mó Membrane-bound proteases play a key role in biology by degrading matrix proteins or shedding adhesion receptors. MT1-MMP metalloproteinase is critical during cancer invasion, angiogenesis, and development. MT1-MMP activity is strictly regulated by internalization,...
Cells, Vol. 9, Pages 347: Cycloastragenol as an Exogenous Enhancer of Chondrogenic Differentiation of Human Adipose-Derived Mesenchymal Stem Cells. A Morphological Study Cells doi: 10.3390/cells9020347 Authors: Marta Anna Szychlinska Giovanna Calabrese Silvia Ravalli Nunziatina Laura Parrinello Stefano Forte Paola Castrogiovanni Elisabetta Pricoco Rosa Imbesi Sergio Castorina Rosalia Leonardi Michelino Di Rosa Giuseppe Musumeci Stem cell therapy and tissue...
Cells, Vol. 9, Pages 346: Beyond Tumor Suppression: Senescence in Cancer Stemness and Tumor Dormancy
Cells, Vol. 9, Pages 346: Beyond Tumor Suppression: Senescence in Cancer Stemness and Tumor Dormancy Cells doi: 10.3390/cells9020346 Authors: Triana-Martínez Loza Domínguez Here, we provide an overview of the importance of cellular fate in cancer as a group of diseases of abnormal cell growth. Tumor development and progression is a highly dynamic process, with several phases of evolution. The existing evidence about the origin and consequences of cancer cell fate specification...
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Diagnostics, Vol. 10, Pages 82: Safety and Efficacy of Salvage Neck Dissection Following Carbon-ion Radiotherapy with Chemotherapy for a Patient with Mucosal Malignant Melanoma of Head and Neck Diagnostics doi: 10.3390/diagnostics10020082 Authors: Suzuki Sasaki Motai Goto Nishikawa Beppu Terada Sawabe Hanai Mucosal malignant melanoma of the head and neck is a rare diagnosis. The safety and efficacy of salvage neck dissection following carbon–ion...
Diagnostics, Vol. 10, Pages 83: Does Endometriosis Influence the Embryo Quality and/or Development? Insights from a Large Retrospective Matched Cohort Study Diagnostics doi: 10.3390/diagnostics10020083 Authors: Sanchez Pagliardini Cermisoni Privitera Makieva Alteri Corti Rabellotti Candiani Viganò In vitro fertilization can be an effective tool to manage the endometriosis-associated infertility, which accounts for 10% of the strategy indications....
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Foods, Vol. 9, Pages 149: Fatty Acid Profiling for the Authentication of Iberian Hams According to the Feeding Regime Foods doi: 10.3390/foods9020149 Authors: Raúl González-Domínguez Ana Sayago Ángeles Fernández-Recamales The quality and sensory characteristics of Iberian ham are closely related to the pig feeding regime. These are mainly due to the inclusion or not of acorns into the diet, which significantly increases the content of monounsaturated fatty acids in this food product....
Foods, Vol. 9, Pages 148: An Overview of the Applications of Nanomaterials and Nanodevices in the Food Industry Foods doi: 10.3390/foods9020148 Authors: Mehwish Shafiq Sumaira Anjum Christophe Hano Iram Anjum Bilal Haider Abbasi The efficient progress in nanotechnology has transformed many aspects of food science and the food industry with enhanced investment and market share. Recent advances in nanomaterials and nanodevices such as nanosensors, nano-emulsions, nanopesticides...
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Healthcare, Vol. 8, Pages 30: Changes in Gait Parameters and Gait Variability in Young Adults during a Cognitive Task while Slope and Flat Walking Healthcare doi: 10.3390/healthcare8010030 Authors: Park Yeo Kwon Song Lim Ha Han Oh This study investigates the effects of a cognitive task while walking on a slope or a flat surface on gait parameters and gait variability in young adults. The participants consisted of thirty healthy young subjects. They were instructed...
Healthcare, Vol. 8, Pages 29: The Energy Efficiency and the Impact of Air Pollution on Health in China Healthcare doi: 10.3390/healthcare8010029 Authors: He Chiu Chang Lin Wang The rapid growth of China’s economy in recent years has greatly improved its citizens’ living standards, but economic growth consumes many various energy sources as well as produces harmful air pollution. Nitrogen oxides, SO2 (sulfur dioxide), and other polluting gases are...
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IJERPH, Vol. 17, Pages 943: Associations between Cadmium Exposure and Taste and Smell Dysfunction: Results from the National Health and Nutrition Examination Survey (NHANES), 2011–2014 International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030943 Authors: Zheng Shen Zhu Hu Background: Cadmium is a ubiquitous environmental pollutant and has been associated with many adverse health outcomes. However, little is known about the effect of cadmium...
IJERPH, Vol. 17, Pages 942: A Double-Activity (Green Algae Toxicity and Bacterial Genotoxicity) 3D-QSAR Model Based on the Comprehensive Index Method and Its Application in Fluoroquinolones’ Modification International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030942 Authors: Yang Liu The comparative molecular similarity index analysis (CoMSIA) model of double-activity quinolones targeting green algae toxicity and bacterial genotoxicity (8:2) was constructed...
IJERPH, Vol. 17, Pages 940: Affect Path to Flood Protective Coping Behaviors using SEM based on A Survey in Shenzhen, China International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030940 Authors: Huang Cao Wang Wang The initial concept of flood control has gradually shifted to flood risk management which emphasizes more public participation. Therefore, understanding the public’s protective coping behavioral patterns to floods is significant,...
IJERPH, Vol. 17, Pages 941: Responses of Periphyton Microbial Growth, Activity, and Pollutant Removal Efficiency to Cu Exposure International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030941 Authors: Zhong Zhao Song Periphyton is an effective matrix for the removal of pollutants in wastewater and has been considered a promising method of bioremediation. However, it still needs to be verified whether periphyton can maintain microbial activity and...
IJERPH, Vol. 17, Pages 937: Digital Diabetes Care System Observations from a Pilot Evaluation Study in Vietnam International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030937 Authors: Tran Quang Khanh Pham Nhu Hao Eytan Roitman Itamar Raz Baruch Marganitt Avivit Cahn Digital technologies are gaining an important role in the management of patients with diabetes. We assessed clinical outcomes and user satisfaction of incorporating a digital...
IJERPH, Vol. 17, Pages 939: The Stakeholders’ Views on Planting Trees to Control Schistosomiasis in China International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030939 Authors: Yang Zhou Jin Sun China has initiated a tree planting program in epidemic regions of schistosomiasis as a part of efforts to eliminate schistosomiasis. More than 518,900 ha of tree plantations have been planted through the program between 2006 and 2015. However, whether...
IJERPH, Vol. 17, Pages 936: Exploration of Disparities in Regions and Specialized Fields of Day Surgery System International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030936 Authors: Gavurova Khouri Korony The main objective of this paper was to find similarities among eight Slovak regions from the viewpoint of five specialized day surgery fields and among specialized day surgery fields from the viewpoint of Slovak regions on the basis of day surgery...
IJERPH, Vol. 17, Pages 935: Behavioral Health at School: Do Three Competences in Road Safety Education Impact the Protective Road Behaviors of Spanish Children? International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030935 Authors: Alonso Gonzalez-Marin Esteban Useche Background: Education in road safety (also known as Road Safety Education—RSE) constitutes, nowadays, an emergent approach for improving present and future road behaviors,...
IJERPH, Vol. 17, Pages 934: Motivation to Donate, Job Crafting, and Organizational Citizenship Behavior in Blood Collection Volunteers in Non-Profit Organizations International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030934 Authors: Nonnis Massidda Cabiddu Cuccu Pedditzi Cortese This study assesses the levels of and relationships between the Motivation to donate, Job crafting propensity, and the Organizational citizenship behavior...
IJERPH, Vol. 17, Pages 933: Comparative Analysis of the Reproduction Accuracy of Main Methods for Finding the Mandible Position in the Centric Relation Using Digital Research Method. Comparison between Analog-to-Digital and Digital Methods: A Preliminary Report International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030933 Authors: Stafeev Ryakhovsky Petrov Chikunov Khizhuk Bykova Vuraki Purpose: To compare the aspect of the reproduction...
IJERPH, Vol. 17, Pages 938: The Role of Vitamins in Oral Health. A Systematic Review and Meta-Analysis International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030938 Authors: Maria Grazia Cagetti Thomas Gerhard Wolf Christian Tennert Nicole Camoni Peter Lingström Guglielmo Campus The association between vitamins and oral health have recently been discussed, yielding increased attention from medical and dental perspectives. The present review...
IJERPH, Vol. 17, Pages 930: Chloroanisoles and Chlorophenols Explain Mold Odor but Their Impact on the Swedish Population Is Attributed to Dampness and Mold International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030930 Authors: Johnny C. Lorentzen Stephanie A. Juran Lena Ernstgård Mats J. Olsson Gunnar Johanson We recently reported that mold odor may be explained by chloroanisoles (CAs) formed by microbial biotransformation of chlorophenols...
IJERPH, Vol. 17, Pages 932: Validation of the Lithuanian Version of the Sociocultural Attitudes towards Appearance Questionnaire-4 (SATAQ-4) in a Student Sample International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030932 Authors: Migle Baceviciene Rasa Jankauskiene Vaiva Balciuniene The Sociocultural Attitudes Towards Appearance Questionnaire-4 (SATAQ-4) is one of the most broadly used self-report tools that assess the general role of sociocultural...
IJERPH, Vol. 17, Pages 931: The Impact of the University Classroom on Managing the Socio-Educational Well-being: A Global Study International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030931 Authors: Mariana-Daniela González-Zamar Luis Ortiz Jiménez Adoración Sánchez Ayala Emilio Abad-Segura The university learning classroom, in addition to a space for activities and architectural object, has a direct impact on the academic motivation, well-being...
IJERPH, Vol. 17, Pages 929: Burnout Syndrome Risk in Child and Adolescent Tennis Players and The Role of Adherence to the Mediterranean Diet International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030929 Authors: Isabel Peraita-Costa Agustin Llopis-Morales Salvador Marí-Bauset Amelia Marí-Sanchis Salvador Marí-Sanchis María Morales-Suárez-Varela This cross-sectional study examined the impact of adherence to Mediterranean diet on burnout syndrome...
IJERPH, Vol. 17, Pages 871: Development of a Black Caucus within the HIV Prevention Trials Network (HPTN): Representing the Perspectives of Black Men Who Have Sex with Men (MSM) International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030871 Authors: Christopher Watson Leo Wilton Jonathan Lucas Lawrence Bryant Gregory Victorianne Kerry Aradhya Sheldon Fields Darrell Wheeler on behalf of the HPTN Black Caucus Black men who have sex...
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IJMS, Vol. 21, Pages 1010: Targeting Age-Dependent Functional and Metabolic Decline of Human Skeletal Muscle: The Geroprotective Role of Exercise, Myokine IL-6, and Vitamin D International Journal of Molecular Sciences doi: 10.3390/ijms21031010 Authors: Clara Crescioli In the elderly, whole-body health largely relies on healthy skeletal muscle, which controls body stability, locomotion, and metabolic homeostasis. Age-related skeletal muscle structural/functional deterioration is associated...
IJMS, Vol. 21, Pages 1009: IL-20 in Acute Kidney Injury: Role in Pathogenesis and Potential as a Therapeutic Target International Journal of Molecular Sciences doi: 10.3390/ijms21031009 Authors: Lin Hsu Acute kidney injury (AKI) causes over 1 million deaths worldwide every year. AKI is now recognized as a major risk factor in the development and progression of chronic kidney disease (CKD). Diabetes is the main cause of CKD as well. Renal fibrosis and inflammation are hallmarks in...
IJMS, Vol. 21, Pages 1008: Inhibitory Effects of β-Caryophyllene on Helicobacter pylori Infection In Vitro and In Vivo International Journal of Molecular Sciences doi: 10.3390/ijms21031008 Authors: Hyun Jun Woo Ji Yeong Yang Min Ho Lee Hyun Woo Kim Hye Jin Kwon Min Park Sung-kyu Kim So-Young Park Sa-Hyun Kim Jong-Bae Kim The human specific bacterial pathogen Helicobacter pylori (H. pylori) is associated with severe gastric diseases, including gastric cancer....
IJMS, Vol. 21, Pages 1004: Adipose-Derived Mesenchymal Stem Cell Chondrospheroids Cultured in Hypoxia and a 3D Porous Chitosan/Chitin Nanocrystal Scaffold as a Platform for Cartilage Tissue Engineering International Journal of Molecular Sciences doi: 10.3390/ijms21031004 Authors: Zubillaga Alonso-Varona Fernandes Salaberria Palomares Articular cartilage degeneration is one of the most common causes of pain and disability in middle-aged and older people. Tissue engineering...
IJMS, Vol. 21, Pages 1006: Phytochemistry, Ethnopharmacology, Pharmacokinetics and Toxicology of Cnidium monnieri (L.) Cusson International Journal of Molecular Sciences doi: 10.3390/ijms21031006 Authors: Sun Yang Lenon Cnidium monnieri (L.) Cusson (CMC) is a traditional Chinese herbal medicine that has been widely grown and used in Asia. It is also known as “She chuang zi” in China (Chinese: 蛇床子), “Jashoshi” in Japan, “Sasangia”...
IJMS, Vol. 21, Pages 1003: Exploration of Binding Mechanism of a Potential Streptococcus pneumoniae Neuraminidase Inhibitor from Herbaceous Plants by Molecular Simulation International Journal of Molecular Sciences doi: 10.3390/ijms21031003 Authors: Guan Zhu Dong Li Yang Wang Shan Streptococcus pneumoniae can cause diseases such as pneumonia. Broad-spectrum antibiotic therapy for Streptococcus pneumoniae is increasingly limited due to the emergence of drug-resistant...
IJMS, Vol. 21, Pages 1005: Role of Gangliosides in Peripheral Pain Mechanisms International Journal of Molecular Sciences doi: 10.3390/ijms21031005 Authors: Sántha Dobos Kis Jancsó Gangliosides are abundantly occurring sialylated glycosphingolipids serving diverse functions in the nervous system. Membrane-localized gangliosides are important components of lipid microdomains (rafts) which determine the distribution of and the interaction among specific membrane proteins....
IJMS, Vol. 21, Pages 1007: Recent Developments in the Design of Non-Biofouling Coatings for Nanoparticles and Surfaces International Journal of Molecular Sciences doi: 10.3390/ijms21031007 Authors: Sanchez-Cano Carril Biofouling is a major issue in the field of nanomedicine and consists of the spontaneous and unwanted adsorption of biomolecules on engineered surfaces. In a biological context and referring to nanoparticles (NPs) acting as nanomedicines, the adsorption of biomolecules...
IJMS, Vol. 21, Pages 998: Chemical and Light Inducible Epigenome Editing International Journal of Molecular Sciences doi: 10.3390/ijms21030998 Authors: Zhao Wang Liang The epigenome defines the unique gene expression patterns and resulting cellular behaviors in different cell types. Epigenome dysregulation has been directly linked to various human diseases. Epigenome editing enabling genome locus-specific targeting of epigenome modifiers to directly alter specific local epigenome...
IJMS, Vol. 21, Pages 997: Effects of the Size, the Number, and the Spatial Arrangement of Reactive Patches on a Sphere on Diffusion-limited Reaction Kinetics: A Comprehensive Study International Journal of Molecular Sciences doi: 10.3390/ijms21030997 Authors: Eun We investigate how the size, the number, and the spatial arrangement of identical nonoverlapping reactive patches on a sphere influence the overall reaction kinetics of bimolecular diffusion-limited (or diffusion-controlled)...
IJMS, Vol. 21, Pages 999: miR-21-5p Under-Expression in Patients with Obstructive Sleep Apnea Modulates Intermittent Hypoxia with Re-Oxygenation-Induced-Cell Apoptosis and Cytotoxicity by Targeting Pro-Inflammatory TNF-α-TLR4 Signaling International Journal of Molecular Sciences doi: 10.3390/ijms21030999 Authors: Chen Hsu Su Chin Liou Wang Lin Lee Lin Hsiao The purpose of this study is to explore the anti-inflammatory role of microRNAs (miR)-21 and...
IJMS, Vol. 21, Pages 1000: Comprehensive Profiling of Tubby-Like Protein Expression Uncovers Ripening-Related TLP Genes in Tomato (Solanum lycopersicum) International Journal of Molecular Sciences doi: 10.3390/ijms21031000 Authors: Yaoxin Zhang Xiaoqing He Dan Su Yuan Feng Haochen Zhao Heng Deng Mingchun Liu Tubby-like proteins (TLPs), which were firstly identified in obese mice, play important roles in male gametophyte development, biotic stress response, and abiotic...
IJMS, Vol. 21, Pages 1001: NADPH Oxidase-Mediated Activation of Neutral Sphingomyelinase Is Responsible for Diesel Particulate Extract-Induced Keratinocyte Apoptosis International Journal of Molecular Sciences doi: 10.3390/ijms21031001 Authors: Hyun-Seok Lee Hye Yoon Park Sung Pil Kwon Bogyeong Kim Yerin Lee Seongeun Kim Kyong-Oh Shin Kyungho Park Human epidermis is positioned at the interface with the external environment, protecting our bodies against external...
IJMS, Vol. 21, Pages 1002: EHMT2 Inhibition Induces Cell Death in Human Non-Small Cell Lung Cancer by Altering the Cholesterol Biosynthesis Pathway International Journal of Molecular Sciences doi: 10.3390/ijms21031002 Authors: Haeun Kim Seo Yoon Choi Jinyeong Lim Anders M. Lindroth Yoon Jung Park Non-small cell lung cancer (NSCLC) is a major subtype of lung cancer. Besides genetic and environmental factors, epigenetic alterations contribute to the tumorigenesis of NSCLC....
IJMS, Vol. 21, Pages 996: Maize ZmBES1/BZR1-5 Decreases ABA Sensitivity and Confers Tolerance to Osmotic Stress in Transgenic Arabidopsis International Journal of Molecular Sciences doi: 10.3390/ijms21030996 Authors: Fuai Sun Haoqiang Yu Jingtao Qu Yang Cao Lei Ding Wenqi Feng Muhammad Hayder Bin Khalid Wanchen Li Fengling Fu The BRI1-EMS suppressor 1 (BES1)/brassinazole-resistant 1 (BZR1) transcription factors, key components in the brassinosteroid signaling...
IJMS, Vol. 21, Pages 992: A Novel Quantitative Approach to Staging and Assessing Recovery from Type 1 Diabetes Mellitus: The Type 1 Diabetes Mellitus Metabolic Recovery Index International Journal of Molecular Sciences doi: 10.3390/ijms21030992 Authors: Tihamer Orban Nara T. Orban Heyam Jalahej Piers E. F. Daubeney Discovery of insulin in 1921 changed the lives of patients with type 1 diabetes (T1DM) forever. What had been a death sentence became a manageable, albeit chronic,...
IJMS, Vol. 21, Pages 995: Production of Gamma-Aminobutyric Acid from Lactic Acid Bacteria: A Systematic Review International Journal of Molecular Sciences doi: 10.3390/ijms21030995 Authors: Yanhua Cui Kai Miao Siripitakyotin Niyaphorn Xiaojun Qu Gamma-aminobutyric acid (GABA) is widely distributed in nature and considered a potent bioactive compound with numerous and important physiological functions, such as anti-hypertensive and antidepressant activities. There is an ever-growing...
IJMS, Vol. 21, Pages 994: AAV-Mediated Gene Delivery to 3D Retinal Organoids Derived from Human Induced Pluripotent Stem Cells International Journal of Molecular Sciences doi: 10.3390/ijms21030994 Authors: Marcela Garita-Hernandez Fiona Routet Laure Guibbal Hanen Khabou Lyes Toualbi Luisa Riancho Sacha Reichman Jens Duebel Jose-Alain Sahel Olivier Goureau Deniz Dalkara Human induced pluripotent stem cells (hiPSCs) promise a great number of future applications...
IJMS, Vol. 21, Pages 993: Contributions of Myosin Light Chain Kinase to Regulation of Epithelial Paracellular Permeability and Mucosal Homeostasis International Journal of Molecular Sciences doi: 10.3390/ijms21030993 Authors: Wei-Qi He Jing Wang Jian-Ying Sheng Juan-Min Zha W. Vallen Graham Jerrold R. Turner Intestinal barrier function is required for the maintenance of mucosal homeostasis. Barrier dysfunction is thought to promote progression of both intestinal and systemic...
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