JCM, Vol. 9, Pages 418: Thromboembolic Events Are Independently Associated with Liver Stiffness in Patients with Fontan Circulation Journal of Clinical Medicine doi: 10.3390/jcm9020418 Authors: Tarek Alsaied Mathias Possner Adam M. Lubert Andrew T. Trout Janvi P. Gandhi BreAnn Garr Joseph S. Palumbo Joseph J. Palermo Angela Lorts Gruschen R. Veldtman Stuart L. Goldstein Alexander Opotowsky Johnathan R. Dillman Background: Thromboembolism (TE) and Fontan-associated...
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JCM, Vol. 9, Pages 411: Opposite Roles of BAP1 in Overall Survival of Uveal Melanoma and Cutaneous Melanoma Journal of Clinical Medicine doi: 10.3390/jcm9020411 Authors: Feng Liu-Smith Yunxia Lu Background: BRCA1-Associated Protein 1 (BAP1) germline mutations predispose individuals to cancers, including uveal melanoma (UM) and cutaneous melanoma (CM). BAP1 loss is common in UM and is associated with a worse prognosis. BAP1 loss is rare in CM and the outcome is unclear. Methods: UM...
Mon Feb 03, 2020 02:00
JCM, Vol. 9, Pages 415: Physical Activity and the Development of Post-Transplant Diabetes Mellitus, and Cardiovascular- and All-Cause Mortality in Renal Transplant Recipients Journal of Clinical Medicine doi: 10.3390/jcm9020415 Authors: Byambasukh Osté Gomes-Neto van den Berg Navis Bakker Corpeleijn (1) Background: Little is currently known about the health impacts of daily-life moderate-to-vigorous physical activity (MVPA) in relation to the development of post-transplant...
Mon Feb 03, 2020 02:00
JCM, Vol. 9, Pages 417: Circulating Arsenic is Associated with Long-Term Risk of Graft Failure in Kidney Transplant Recipients: A Prospective Cohort Study Journal of Clinical Medicine doi: 10.3390/jcm9020417 Authors: Camilo G. Sotomayor Dion Groothof Joppe J. Vodegel Tomás A. Gacitúa António W. Gomes-Neto Maryse C. J. Osté Robert A. Pol Catterina Ferreccio Stefan P. Berger Guillermo Chong Riemer H. J. A. Slart Ramón Rodrigo Gerjan J. Navis Daan J. Touw...
Mon Feb 03, 2020 02:00
JCM, Vol. 9, Pages 412: Sorting Rare ALS Genetic Variants by Targeted Re-Sequencing Panel in Italian Patients: OPTN, VCP, and SQSTM1 Variants Account for 3% of Rare Genetic Forms Journal of Clinical Medicine doi: 10.3390/jcm9020412 Authors: Pensato Magri Bella Tannorella Bersano Sorarù Gatti Ticozzi Taroni Lauria Mariotti Gellera Amyotrophic lateral sclerosis (ALS) is an adult-onset progressive neurodegenerative disease due to motor neuron...
Mon Feb 03, 2020 02:00
JCM, Vol. 9, Pages 413: Prognostic Significance of Glucose Metabolism as GLUT1 in Patients with Pulmonary Pleomorphic Carcinoma Journal of Clinical Medicine doi: 10.3390/jcm9020413 Authors: Imai Kaira Endoh Imaizumi Goto Kamiyoshihara Kosaka Yajima Ohtaki Osaki Kogure Tanaka Fujita Oyama Minato Asao Shirabe Glucose metabolism is necessary for tumor progression, metastasis, and survival in various human cancers. Glucose...
Mon Feb 03, 2020 02:00
JCM, Vol. 9, Pages 414: Cardiovascular Events After Community-Acquired Pneumonia: A Global Perspective with Systematic Review and Meta-Analysis of Observational Studies Journal of Clinical Medicine doi: 10.3390/jcm9020414 Authors: Tralhão Póvoa Acute cardiovascular disease after community-acquired pneumonia is a well-accepted complication for which definitive treatment strategies are lacking. These complications share some common features but have distinct diagnostic and treatment...
Mon Feb 03, 2020 02:00
JCM, Vol. 9, Pages 409: Cardiovascular and Lung Involvement in Patients with Autoimmune Pancreatitis
JCM, Vol. 9, Pages 409: Cardiovascular and Lung Involvement in Patients with Autoimmune Pancreatitis Journal of Clinical Medicine doi: 10.3390/jcm9020409 Authors: Sara Nikolic Katharina Brehmer Nikola Panic Roberto Valente J.-Matthias Löhr Miroslav Vujasinovic Introduction: Immunoglobulin G4-related disease (IgG4-RD) is a systemic immune-mediated disease characterised pathologically by the infiltration of IgG4-bearing plasma cells into the involved organs. Autoimmune pancreatitis...
Mon Feb 03, 2020 02:00
JCM, Vol. 9, Pages 416: Initial Glaucoma Medication in the Hypertensive Phase Following Ahmed Valve Implantation: A Comparison of Results Achieved Using Aqueous Suppressants and Prostaglandin Analogs Journal of Clinical Medicine doi: 10.3390/jcm9020416 Authors: Lee Park Jung Background: To compare the effects of aqueous suppressants (AS) and prostaglandin (PG) analogs during the hypertensive phase on intraocular pressure (IOP) and surgical outcomes. Methods: In this retrospective,...
Mon Feb 03, 2020 02:00
JCM, Vol. 9, Pages 406: From Spermiogram to Bio-Functional Sperm Parameters: When and Why Request Them? Journal of Clinical Medicine doi: 10.3390/jcm9020406 Authors: Condorelli Calogero Russo La Vignera Abstract: The aim of this experimental study was to evaluate whether infertile patients may benefit from the evaluation of bio-functional sperm parameters in addition to the conventional semen analysis. To accomplish this, we evaluated the correlation between conventional...
Mon Feb 03, 2020 02:00
JCM, Vol. 9, Pages 410: Skeletal and Respiratory Muscle Dysfunctions in Pulmonary Arterial Hypertension Journal of Clinical Medicine doi: 10.3390/jcm9020410 Authors: Riou Pizzimenti Enache Charloux Canuet Andres Talha Meyer Geny Pulmonary arterial hypertension (PAH) is a rare disease, which leads to the progressive loss and remodeling of the pulmonary vessels, right heart failure, and death. Different clinical presentations can be responsible for such...
Mon Feb 03, 2020 02:00
JCM, Vol. 9, Pages 407: Therapeutic Options for the Treatment of Interstitial Lung Disease Related to Connective Tissue Diseases. A Narrative Review Journal of Clinical Medicine doi: 10.3390/jcm9020407 Authors: Vacchi Sebastiani Cassone Cerri Casa Salvarani Manfredi Interstitial lung disease (ILD) is one of the most serious pulmonary complications of connective tissue diseases (CTDs) and it is characterized by a deep impact on morbidity and mortality. Due to...
Mon Feb 03, 2020 02:00
JCM, Vol. 9, Pages 408: Endoscopist’s Judgment Is as Useful as Risk Scores for Predicting Outcome in Peptic Ulcer Bleeding: A Multicenter Study Journal of Clinical Medicine doi: 10.3390/jcm9020408 Authors: Brullet Garcia-Iglesias Calvet Papo Planella Pardo Junquera Montoliu Ballester Martinez-Bauer Suarez Campo Background: Guidelines recommend using prognostic scales for risk stratification in patients with non-variceal upper gastrointestinal...
Mon Feb 03, 2020 02:00
JCM, Vol. 9, Pages 404: Does Chronic Kidney Disease Facilitate Malignant Myocardial Fibrosis in Heart Failure with Preserved Ejection Fraction of Hypertensive Origin? Journal of Clinical Medicine doi: 10.3390/jcm9020404 Authors: Rocio Eiros Gregorio Romero-González Juan Jose Gavira Oscar Beloqui Inmaculada Colina Manuel Fortún Landecho Begoña López Arantxa González Javier Díez Susana Ravassa In hypertensive patients with heart failure (HF) a serum biomarker...
Mon Feb 03, 2020 02:00
JCM, Vol. 9, Pages 405: Involvement of the Endocrine-Disrupting Chemical Bisphenol A (BPA) in Human Placentation Journal of Clinical Medicine doi: 10.3390/jcm9020405 Authors: Sophie-Christine de Aguiar Greca Ioannis Kyrou Ryan Pink Harpal Randeva Dimitris Grammatopoulos Elisabete Silva Emmanouil Karteris Background: Endocrine-disrupting chemicals (EDCs) are environmental chemicals/toxicants that humans are exposed to, interfering with the action of multiple hormones....
Mon Feb 03, 2020 02:00
JoF, Vol. 6, Pages 21: Contributions of the Biofilm Matrix to Candida Pathogenesis Journal of Fungi doi: 10.3390/jof6010021 Authors: Jeniel E. Nett David R. Andes In healthcare settings, Candida spp. cause invasive disease with high mortality. The overwhelming majority of cases are associated with the use of critically-needed medical devices, such as vascular catheters. On the surface of these indwelling materials, Candida forms resilient, adherent biofilm communities. A hallmark...
Mon Feb 03, 2020 02:00
JPM, Vol. 10, Pages 7: Healthcare Utilization and Costs after Receiving a Positive BRCA1/2 Result from a Genomic Screening Program Journal of Personalized Medicine doi: 10.3390/jpm10010007 Authors: Jing Hao Dina Hassen Kandamurugu Manickam Michael F. Murray Dustin N. Hartzel Yirui Hu Kunpeng Liu Alanna Kulchak Rahm Marc S. Williams Amanda Lazzeri Adam Buchanan Amy Sturm Susan R. Snyder Population genomic screening has been demonstrated to detect at-risk...
Mon Feb 03, 2020 02:00
JPM, Vol. 10, Pages 6: Experimental Biointegration of a Titanium Implant in Delayed Mandibular Reconstruction Journal of Personalized Medicine doi: 10.3390/jpm10010006 Authors: Alexander Dolgolev Igor Reshetov Dmitry Svyatoslavov Mikhail Sinelnikov Konstantin Kudrin Vladimir Dub Vladimir Put Vladimir Anikin Background: Mandibular reconstruction, after extensive resection of the mandible for the treatment of oral cancer, is a well-known procedure, however, relatively...
Mon Feb 03, 2020 02:00
Medicina, Vol. 56, Pages 58: 5-Lipooxygenase Derivatives as Serum Biomarkers of a Successful Dietary Intervention in Patients with NonAlcoholic Fatty Liver Disease Medicina doi: 10.3390/medicina56020058 Authors: Marcin Banaszczak Dominika Maciejewska Arleta Drozd Karina Ryterska Dominika Jamioł Milc Joanna Raszeja-Wyszomirska Ewa Wunsch Pedro González-Muniesa Ewa Stachowska Background: It was previously shown that a bodyweight reduction among patients with nonalcoholic...
Mon Feb 03, 2020 02:00
Microorganisms, Vol. 8, Pages 208: Aquatic Thermal Reservoirs of Microbial Life in a Remote and Extreme High Andean Hydrothermal System Microorganisms doi: 10.3390/microorganisms8020208 Authors: Pérez Cortés Marchant Dorador Molina Cornejo-D’Ottone Hernández Jeffrey Barahona Hengst Hydrothermal systems are ideal to understand how microbial communities cope with challenging conditions. Lirima, our study site, is a polyextreme, high-altitude, hydrothermal...
Mon Feb 03, 2020 02:00
Microorganisms, Vol. 8, Pages 207: The Root Nodule Microbiome of Cultivated and Wild Halophytic Legumes Showed Similar Diversity but Distinct Community Structure in Yellow River Delta Saline Soils Microorganisms doi: 10.3390/microorganisms8020207 Authors: Yanfen Zheng Jing Liang Dong-Lin Zhao Chen Meng Zong-Chang Xu Zhi-Hong Xie Cheng-Sheng Zhang Symbiotic associations between leguminous plants and their nodule microbiome play a key role in sustainable agriculture by...
Mon Feb 03, 2020 02:00
Molecules, Vol. 25, Pages 649: A Review of Biologically Active Natural Products from Mediterranean Wild Edible Plants: Benefits in the Treatment of Obesity and Its Related Disorders Molecules doi: 10.3390/molecules25030649 Authors: Mariangela Marrelli Giancarlo Statti Filomena Conforti Wild foods constitute an essential component of people’s diets around the world. According to the Food and Agriculture Organization (FAO), over 100 million people in the EU consume wild...
Mon Feb 03, 2020 02:00
Molecules, Vol. 25, Pages 651: Efficient Biodiesel Production Catalyzed by Nanobioconjugate of Lipase from Pseudomonas fluorescens Molecules doi: 10.3390/molecules25030651 Authors: Bartha-Vári Moisă Bencze Irimie Paizs Toșa The Amano lipase from Pseudomonas fluorescens (L-AK) was covalently immobilized on various carbon nanomaterials (functionalized single-walled carbon nanotubes and graphene oxide) and tested for biodiesel production. Using the most active lipase...
Mon Feb 03, 2020 02:00
Molecules, Vol. 25, Pages 650: Antitumoral Properties of Natural Products Molecules doi: 10.3390/molecules25030650 Authors: Fabiani Cancer is one of the major causes of death worldwide. It is a multifactorial heterogeneous disease characterized by a multistep process initiated by genetic alterations of normal cells which become malignant cells [...]
Mon Feb 03, 2020 02:00
Molecules, Vol. 25, Pages 648: Organocatalytic Asymmetric Aldol Reaction of Arylglyoxals and Hydroxyacetone: Enantioselective Synthesis of 2,3-Dihydroxy-1,4-diones Molecules doi: 10.3390/molecules25030648 Authors: Yu-Hao Zhou Yu-Zu Zhang Zhu-Lian Wu Tian Cai Wei Wen Qi-Xiang Guo A highly efficient quinine-derived primary-amine-catalyzed asymmetric aldol addition of hydroxyacetone to arylglyoxals is described. Structurally diverse anti-2,3-dihydroxy-1,4-diones were generated...
Mon Feb 03, 2020 02:00
Molecules, Vol. 25, Pages 647: Euryops pectinatus L. Flower Extract Inhibits P-glycoprotein and Reverses Multi-Drug Resistance in Cancer Cells: A Mechanistic Study Molecules doi: 10.3390/molecules25030647 Authors: Wafaa M. Elkady Iriny M. Ayoub Yousra Abdel-Mottaleb Mohamed F. ElShafie Michael Wink Euryops pectinatus is a South African ornamental plant belonging to family Asteraceae. The present work evaluates the cytotoxic activity and phytochemical profile of the flower...
Mon Feb 03, 2020 02:00
Molecules, Vol. 25, Pages 645: Discovery of Novel Inhibitors Targeting Multi-UDP-hexose Pyrophosphorylases as Anticancer Agents Molecules doi: 10.3390/molecules25030645 Authors: Yueqin Yang Hariprasad Vankayalapati Manshu Tang Yingbo Zheng Yingri Li Cong Ma Kent Lai To minimize treatment toxicities, recent anti-cancer research efforts have switched from broad-based chemotherapy to targeted therapy, and emerging data show that altered cellular metabolism in cancerous...
Mon Feb 03, 2020 02:00
Molecules, Vol. 25, Pages 646: Substrate-Specific Activation of α-Secretase by 7-Deoxy-Trans-Dihydronarciclasine Increases Non-Amyloidogenic Processing of β-Amyloid Protein Precursor Molecules doi: 10.3390/molecules25030646 Authors: Yoon Sun Chun Yoon Young Cho Oh Hoon Kwon Dong Zhao Hyun Ok Yang Sungkwon Chung Accumulation of β-amyloid (Aβ) in the brain has been implicated in the pathology of Alzheimer’s disease (AD). Aβ is produced...
Mon Feb 03, 2020 02:00
Molecules, Vol. 25, Pages 644: Chromium-Based Polypyrrole/MIL-101 Nanocomposite as an Effective Sorbent for Headspace Microextraction of Methyl tert-Butyl Ether in Soil Samples Molecules doi: 10.3390/molecules25030644 Authors: Jila Darabi Alireza Ghiasvand The performance of headspace solid-phase microextraction (HS-SPME) was upgraded by easy and low-cost preparation of a new nanocomposite fiber. A polypyrrole/chromium-based metal–organic framework, PPy@MIL-101(Cr), nanocomposite...
Mon Feb 03, 2020 02:00
Nanomaterials, Vol. 10, Pages 260: Novel Unsaturated Polyester Nanocomposites via Hybrid 3D POSS-Modified Graphene Oxide Reinforcement: Electro-Technical Application Perspective Nanomaterials doi: 10.3390/nano10020260 Authors: Nidhin Divakaran Manoj B. Kale T. Senthil Suhail Mubarak Duraisami Dhamodharan Lixin Wu Jianlei Wang The latest trends in technologies has shifted the focus to developing innovative methods for comprehensive property enhancement of the polymer...
Mon Feb 03, 2020 02:00
Nutrients, Vol. 12, Pages 403: Effect of Extra Virgin Olive Oil and Traditional Brazilian Diet on the Bone Health Parameters of Severely Obese Adults: A Randomized Controlled Trial Nutrients doi: 10.3390/nu12020403 Authors: Camila Kellen de Souza Cardoso Annelisa Silva e Alves de Carvalho Santos Lorena Pereira de Souza Rosa Carolina Rodrigues Mendonça Priscila Valverde de Oliveira Vitorino Maria do Rosário Gondim Peixoto Érika Aparecida Silveira Dietary interventions...
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Nutrients, Vol. 12, Pages 402: Plasma Glutamine Levels in Relation to Intensive Care Unit Patient Outcome Nutrients doi: 10.3390/nu12020402 Authors: Blaauw Nel Schleicher Low and high plasma glutamine levels are associated with increased mortality. This study aimed to measure glutamine levels in critically ill patients admitted to the intensive care unit (ICU) , correlate the glutamine values with clinical outcomes, and identify proxy indicators of abnormal glutamine levels....
Mon Feb 03, 2020 02:00
Nutrients, Vol. 12, Pages 401: Reply: “Comment on Search and Selection of Probiotics that Improve Mucositis Symptoms in Oncologic Patients. A Systematic Review. Nutrients 2019, 11, 2322” Nutrients doi: 10.3390/nu12020401 Authors: José Antonio Picó-Monllor José Manuel Mingot-Ascencao In the article, “Search and Selection of Probiotics That Improve Mucositis Symptoms in Oncologic Patients [...]
Mon Feb 03, 2020 02:00
Pharmaceuticals, Vol. 13, Pages 25: Synthesis and Bioactivity of Phthalimide Analogs as Potential Drugs to Treat Schistosomiasis, a Neglected Disease of Poverty Pharmaceuticals doi: 10.3390/ph13020025 Authors: Singh El-Sakkary Skinner Sharma Ottilie Antonova-Koch Kumar Winzeler Poonam R. Caffrey Rathi The neglected tropical disease, schistosomiasis, is caused by trematode blood flukes of the Schistosoma genus and infects approximately 200 million...
Mon Feb 03, 2020 02:00
Pharmaceutics, Vol. 12, Pages 124: Polymers for Extrusion-Based 3D Printing of Pharmaceuticals: A Holistic Materials–Process Perspective Pharmaceutics doi: 10.3390/pharmaceutics12020124 Authors: Azad Olawuni Kimbell Badruddoza Hossain Sultana Three dimensional (3D) printing as an advanced manufacturing technology is progressing to be established in the pharmaceutical industry to overcome the traditional manufacturing regime of 'one size fits for all'. Using 3D printing,...
Mon Feb 03, 2020 02:00
Pharmaceutics, Vol. 12, Pages 126: Improving the Oral Bioavailability of an Anti-Glioma Prodrug CAT3 Using Novel Solid Lipid Nanoparticles Containing Oleic Acid-CAT3 Conjugates Pharmaceutics doi: 10.3390/pharmaceutics12020126 Authors: Wang Li Ye Wang Wang Hu Wang Dong Xia Yang Gao Gao Liu 13a-(S)-3-pivaloyloxyl-6,7-dimethoxyphenanthro(9,10-b)-indolizidine (CAT3) is a novel oral anti-glioma pro-drug with a potent anti-tumor effect against...
Mon Feb 03, 2020 02:00
Pharmaceutics, Vol. 12, Pages 129: Pharmacokinetics and Intestinal Metabolism of Compound K in Rats and Mice Pharmaceutics doi: 10.3390/pharmaceutics12020129 Authors: Jeon Kang Lee Jin Choi Song We aimed to investigate the plasma concentration, tissue distribution, and elimination of compound K following the intravenous administration of compound K (2 mg/kg) in rats and mice. The plasma concentrations of compound K in mice were much higher (about five-fold) than...
Mon Feb 03, 2020 02:00
Pharmaceutics, Vol. 12, Pages 127: Species Differences in Stereoselective Pharmacokinetics of HSG4112, A New Anti-Obesity Agent Pharmaceutics doi: 10.3390/pharmaceutics12020127 Authors: Bae Choi Ji Yoo Kim Yoo HSG4112, a racemic drug, is a new anti-obesity agent. In this study, the stereoselective pharmacokinetics of HSG4112 were investigated in rats and dogs, and the underlying mechanism was investigated. The plasma concentrations of HSG4112(S) and HSG4112(R) were...
Mon Feb 03, 2020 02:00
Pharmaceutics, Vol. 12, Pages 128: Synergistic Mechanisms of Constituents in Herbal Extracts during Intestinal Absorption: Focus on Natural Occurring Nanoparticles Pharmaceutics doi: 10.3390/pharmaceutics12020128 Authors: Zhao Luan Zheng Tian Zhao Zhang Ma The systematic separation strategy has long and widely been applied in the research and development of herbal medicines. However, the pharmacological effects of many bioactive constituents are much weaker than...
Mon Feb 03, 2020 02:00
Pharmaceutics, Vol. 12, Pages 125: Semi-Mechanism-Based Pharmacokinetic-Toxicodynamic Model of Oxaliplatin-Induced Acute and Chronic Neuropathy Pharmaceutics doi: 10.3390/pharmaceutics12020125 Authors: Kobuchi Shimizu Ito Oxaliplatin (L-OHP) is widely prescribed for treating gastroenterological cancer. L-OHP-induced peripheral neuropathy is a critical toxic effect that limits the dosage of L-OHP. An ideal chemotherapeutic strategy that does not result in severe peripheral neuropathy...
Mon Feb 03, 2020 02:00
Pharmaceutics, Vol. 12, Pages 123: Enteric Hard Capsules for Targeting the Small Intestine: Positive Correlation between In Vitro Disintegration and Dissolution Times Pharmaceutics doi: 10.3390/pharmaceutics12020123 Authors: Fu Al-Gousous Blechar Langguth In this study, the potential for correlation between disintegration and dissolution performance of enteric-coated (EC) dosage forms was investigated. Different enteric hard shell capsule formulations containing caffeine...
Mon Feb 03, 2020 02:00
Pharmaceutics, Vol. 12, Pages 130: Self-Microemulsifying Drug Delivery System of Phillygenin: Formulation Development, Characterization and Pharmacokinetic Evaluation Pharmaceutics doi: 10.3390/pharmaceutics12020130 Authors: Wang Yan Tian Xue Tang Zhang Phillygenin, as an active ingredient of Forsythia suspensa, possesses a wide range of biological and pharmacological activity. However, its development and application are restricted due to its poor bioavailability...
Mon Feb 03, 2020 02:00
Pharmaceutics, Vol. 12, Pages 122: Biological Evaluation of Naproxen–Dehydrodipeptide Conjugates with Self-Hydrogelation Capacity as Dual LOX/COX Inhibitors Pharmaceutics doi: 10.3390/pharmaceutics12020122 Authors: Rute Moreira Peter J. Jervis André Carvalho Paula M. T. Ferreira José A. Martins Patrícia Valentão Paula B. Andrade David M. Perreira The use of peptide–drug conjugates is emerging as a powerful strategy for targeted drug delivery. Previously,...
Mon Feb 03, 2020 02:00
Pharmaceutics, Vol. 12, Pages 121: New Preclinical Development of a c-Met Inhibitor and Its Combined Anti-Tumor Effect in c-Met-Amplified NSCLC Pharmaceutics doi: 10.3390/pharmaceutics12020121 Authors: Nam Ah Kim Sungyoul Hong Ki Hyun Kim Du Hyung Choi Joo Seok Kim Kyung Eui Park Jun Young Choi Young Kee Shin Seong Hoon Jeong c-Met is a receptor tyrosine kinase with no commercially available product despite being a pivotal target in cancer progression. Unlike...
Mon Feb 03, 2020 02:00
Pharmaceutics, Vol. 12, Pages 120: Growth Factors Delivery System for Skin Regeneration: An Advanced Wound Dressing Pharmaceutics doi: 10.3390/pharmaceutics12020120 Authors: Marta Nardini Sara Perteghella Luca Mastracci Federica Grillo Giorgio Marrubini Elia Bari Matteo Formica Chiara Gentili Ranieri Cancedda Maria Luisa Torre Maddalena Mastrogiacomo Standard treatments of chronic skin ulcers based on the direct application of dressings still present several...
Mon Feb 03, 2020 02:00
Pharmacy, Vol. 8, Pages 15: An Authentic, Practice-Based Assessment as a Catalyst for Continuous Professional Development Pharmacy doi: 10.3390/pharmacy8010015 Authors: Sandra Winkelbauer Over the last ten years, pharmacy practice has changed significantly in Canada. It is more important than ever to ensure that the profession engages in continuing professional development in order to keep up with changing practice and changing public demand and scrutiny. The question is, how do we ensure...
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Plants, Vol. 9, Pages 186: Molecular Characterization of the Dwarf53 Gene Homolog in Dasypyrum villosum Plants doi: 10.3390/plants9020186 Authors: Bazhenov Chernook Kroupin Karlov Divashuk The Dwarf53 (D53) gene, first studied in rice, encodes a protein that acts as a repressor of the physiological response of plants to strigolactones—substances that regulate the activity of axillary buds, stem growth, branching of roots and other physiological processes. In...
Mon Feb 03, 2020 02:00
Plants, Vol. 9, Pages 185: Expression Profile of PIN-Formed Auxin Efflux Carrier Genes during IBA-Induced In Vitro Adventitious Rooting in Olea europaea L. Plants doi: 10.3390/plants9020185 Authors: Velada Cardoso Porfirio Peixe Exogenous auxins supplementation plays a central role in the formation of adventitious roots (AR) for several plant species. However, the molecular mechanisms underlying the process of adventitious rooting are still not completely understood and...
Mon Feb 03, 2020 02:00
Plants, Vol. 9, Pages 184: Natural Variation in Adventitious Rooting in the Alpine Perennial Arabis alpina Plants doi: 10.3390/plants9020184 Authors: Priyanka Mishra Adrian Roggen Karin Ljung Maria C. Albani Arctic alpine species follow a mixed clonal-sexual reproductive strategy based on the environmental conditions at flowering. Here, we explored the natural variation for adventitious root formation among genotypes of the alpine perennial Arabis alpina that show differences...
Mon Feb 03, 2020 02:00
Religions, Vol. 11, Pages 69: Long White Procession: Social Order and Liberation in a Religious Ritual Religions doi: 10.3390/rel11020069 Authors: Sharaby The Seged is a pilgrimage holiday celebrated by the Jews of Ethiopia on 29 November. Its purpose is to reconstruct a renewal of the covenant between the Jewish People and God in Jerusalem and at Sinai and to strengthen their religious belief. The research is based on a qualitative research method and uses interviews with religious...
Mon Feb 03, 2020 02:00
Risks, Vol. 8, Pages 14: Loss Reserving Estimation With Correlated Run-Off Triangles in a Quantile Longitudinal Model Risks doi: 10.3390/risks8010014 Authors: Ioannis Badounas Georgios Pitselis In this paper, we consider a loss reserving model for a general insurance portfolio consisting of a number of correlated run-off triangles that can be embedded within the quantile regression model for longitudinal data. The model proposes a combination of the between- and within-subportfolios...
Mon Feb 03, 2020 02:00
Risks, Vol. 8, Pages 13: A Comprehensive Stability Indicator for Banks Risks doi: 10.3390/risks8010013 Authors: Robert J. Powell Duc H. Vo Stability indicators are essential to banks in order to identify instability caused by adverse economic circumstances or increasing risks such as customer defaults. This paper develops a novel comprehensive stability indicator (CSI) that can readily be used by individual banks, or by regulators to benchmark financial health across banks. The CSI...
Mon Feb 03, 2020 02:00
Safety, Vol. 6, Pages 7: Levee System Reliability Modeling: The Length Effect and Bayesian Updating Safety doi: 10.3390/safety6010007 Authors: Kathryn Roscoe Anca Hanea Ruben Jongejan Ton Vrouwenvelder In levee system reliability, the length effect is the term given to the phenomenon that the longer the levee, the higher the probability that it will have a weak spot and fail. Quantitatively, it is the ratio of the segment failure probability to the cross-sectional failure probability....
Mon Feb 03, 2020 02:00
Technologies, Vol. 8, Pages 14: Demonstration of Reconfigurable BPFs with Wide Tuning Bandwidth Range Using 3λ/4 Open- and λ/2 Short- Ended Stubs Technologies doi: 10.3390/technologies8010014 Authors: Arain Quddious Nikolaou Vryonides In this paper, two implementations of reconfigurable bandwidth bandpass filters (BPFs) are demonstrated both operating at a fixed center frequency of 2.4 GHz. The proposed reconfigurable bandwidth filters are based on a square ring resonator...
Mon Feb 03, 2020 02:00
Toxins, Vol. 12, Pages 98: Effect of Botulinum Toxin A on Bladder Pain—Molecular Evidence and Animal Studies Toxins doi: 10.3390/toxins12020098 Authors: Ting-Chun Yeh Po-Cheng Chen Yann-Rong Su Hann-Chorng Kuo Botulinum toxin A (BTX-A) is a powerful neurotoxin with long-lasting activity that blocks muscle contractions. In addition to effects on neuromuscular junctions, BTX-A also plays a role in sensory feedback loops, suggesting the potentiality for pain relief. Although the...
Mon Feb 03, 2020 02:00
Toxins, Vol. 12, Pages 97: Cultivation Area Affects the Presence of Fungal Communities and Secondary Metabolites in Italian Durum Wheat Grains Toxins doi: 10.3390/toxins12020097 Authors: Beccari Prodi Senatore Balmas Tini Onofri Pedini Sulyok Brocca Covarelli In this study, durum wheat kernels harvested in three climatically different Italian cultivation areas (Emilia Romagna, Umbria and Sardinia) in 2015, were analyzed with a combination of different...
Mon Feb 03, 2020 02:00
TropicalMed, Vol. 5, Pages 20: Morbidity and Mortality Due to Schistosoma mansoni Related Periportal Fibrosis: Could Early Diagnosis of Varices Improve the Outcome Following Available Treatment Modalities in Sub Saharan Africa? A Scoping Review Tropical Medicine and Infectious Disease doi: 10.3390/tropicalmed5010020 Authors: Daniel W. Gunda Semvua B. Kilonzo Paulina M. Manyiri Robert N. Peck Humphrey D. Mazigo Schistosomiasis affects about 240 million people worldwide and...
Mon Feb 03, 2020 02:00
Vaccines, Vol. 8, Pages 65: MiRNA Targeted NP Genome of Live Attenuated Influenza Vaccines Provide Cross-Protection against a Lethal Influenza Virus Infection Vaccines doi: 10.3390/vaccines8010065 Authors: Feixia Gao Tianhan Yang Xueying Liu Feifei Xiong Jian Luo Yinglei Yi Jiangfeng Fan Ze Chen Wen-Song Tan The miRNA-based strategy has been used to develop live attenuated influenza vaccines. In this study, the nucleoprotein (NP) genome segment of the influenza...
Mon Feb 03, 2020 02:00
Vaccines, Vol. 8, Pages 66: Seroprevalence to Measles Virus after Vaccination or Natural Infection in an Adult Population, in Italy Vaccines doi: 10.3390/vaccines8010066 Authors: Gabriele Anichini Claudia Gandolfo Simonetta Fabrizi Giovan Battista Miceli Chiara Terrosi Gianni Gori Savellini Shibily Prathyumnan Daniela Orsi Giuseppe Battista Maria Grazia Cusi An increase in measles cases worldwide, with outbreaks, has been registered in the last few years, despite...
Mon Feb 03, 2020 02:00
Veterinary Sciences, Vol. 7, Pages 17: Plasma Concentration Rise after the Intramuscular Administration of High Dose Medetomidine (0.13 mg/kg) for Semen Collection in Cats Veterinary Sciences doi: 10.3390/vetsci7010017 Authors: Noemi Romagnoli Carlotta Lambertini Daniele Zambelli Marco Cunto Giulia Ballotta Andrea Barbarossa High dose medetomidine 0.13 mg/kg can be used for semen collection in cats with variable results in terms of quantity and quality. Therefore, a variation...
Mon Feb 03, 2020 02:00
Viruses, Vol. 12, Pages 172: Herpesviruses in Head and Neck Cancers Viruses doi: 10.3390/v12020172 Authors: Mikołaj Wołącewicz Rafał Becht Ewelina Grywalska Paulina Niedźwiedzka-Rystwej Head and neck cancers arise in the mucosa lining the oral cavity, oropharynx, hypopharynx, larynx, sinonasal tract, and nasopharynx. The etiology of head and neck cancers is complex and involves many factors, including the presence of oncogenic viruses. These types of cancers are among the most...
Mon Feb 03, 2020 02:00
Viruses, Vol. 12, Pages 171: Estimating the Risk of Human Herpesvirus 6 and Cytomegalovirus Transmission to Ugandan Infants from Viral Shedding in Saliva by Household Contacts Viruses doi: 10.3390/v12020171 Authors: Bryan T. Mayer Elizabeth M. Krantz Anna Wald Lawrence Corey Corey Casper Soren Gantt Joshua T. Schiffer Human herpesvirus 6 (HHV-6) and cytomegalovirus (CMV) infections are common in early childhood. In a prospective Ugandan birth cohort study, most infants...
Mon Feb 03, 2020 02:00
Vision, Vol. 4, Pages 11: Eye Movements and Fixation-Related Potentials in Reading: A Review Vision doi: 10.3390/vision4010011 Authors: Federica Degno Simon P. Liversedge The present review is addressed to researchers in the field of reading and psycholinguistics who are both familiar with and new to co-registration research of eye movements (EMs) and fixation related-potentials (FRPs) in reading. At the outset, we consider a conundrum relating to timing discrepancies between EM and...
Mon Feb 03, 2020 02:00
Water, Vol. 12, Pages 408: Correction: Combination of Discrete Element Method and Artificial Neural Network for Predicting Porosity of Gravel-Bed River. Water 2019, 11(7), 1461 Water doi: 10.3390/w12020408 Authors: Van Hieu Bui Minh Duc Bui Peter Rutschmann We have found one error in Equation (2) (duplicate with Equation (1)) in our paper published in the Water Journal [1]: (1) m i d u → i dt = m i g → + ∑ k ...
Mon Feb 03, 2020 02:00
Water, Vol. 12, Pages 406: Real-Time Control of Urban Water Cycle under Cyber-Physical Systems Framework Water doi: 10.3390/w12020406 Authors: Sun Puig Cembrano The urban water cycle (UWC), which is composed of the water supply system (WSS) and urban drainage system (UDS), is a critical infrastructure required for the functioning of urban society. Considering the growing pollution and subsequent water scarcity caused by increasing urbanization and climate change, efficient UWC...
Mon Feb 03, 2020 02:00
Water, Vol. 12, Pages 407: Effects of Light Intensity and Exposure Period on the Growth and Stress Responses of Two Cyanobacteria Species: Pseudanabaena galeata and Microcystis aeruginosa Water doi: 10.3390/w12020407 Authors: Muhetaer Asaeda Jayasanka Baniya Abeynayaka Rashid Yan Light is an important factor that affects cyanobacterial growth and changes in light can influence their growth and physiology. However, an information gap exists regarding light-induced...
Mon Feb 03, 2020 02:00
Water, Vol. 12, Pages 405: Reconstructing Six Decades of Surface Temperatures at a Shallow Lake Water doi: 10.3390/w12020405 Authors: Xin Zhang Kaicun Wang Marieke A. Frassl Bertram Boehrer Lake surface water temperature (LSWT) plays a fundamental role in the lake energy budget. However, direct observations of LSWT require considerable effort for acquisition and hence are rare relative to a large number of lakes. In lakes where LSWT has not been covered sufficiently by in situ...
Mon Feb 03, 2020 02:00
Water, Vol. 12, Pages 404: Spatiotemporal Relationships of Phytoplankton Blooms, Drought, and Rainstorms in Freshwater Reservoirs Water doi: 10.3390/w12020404 Authors: Abigail S. Knapp Adam M. Milewski Algal blooms, especially those composed of toxic phytoplankton, are a global threat to eutrophic and mesotrophic freshwater reservoirs. While extreme hydrologic events such as flooding and drought have been shown to control bloom onset and success, the spatiotemporal dynamics of these...
Mon Feb 03, 2020 02:00
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