Antibiotics, Vol. 9, Pages 126: Nonocarbolines A–E, β-Carboline Antibiotics Produced by the Rare Actinobacterium Nonomuraea sp. from Indonesia Antibiotics doi: 10.3390/antibiotics9030126 Authors: Gian Primahana Chandra Risdian Tjandrawati Mozef Enge Sudarman Matthias Köck Joachim Wink Marc Stadler During the course of our ongoing screening for novel biologically active secondary metabolites, the rare Actinobacterium, Nonomuraea sp. 1808210CR was found to produce five...
Tue Mar 17, 2020 02:00
Antibiotics, Vol. 9, Pages 125: Application of Response Surface Methodology to Evaluate Photodynamic Inactivation Mediated by Eosin Y and 530 nm LED against Staphylococcus aureus Antibiotics doi: 10.3390/antibiotics9030125 Authors: Adriele R. Santos Alex F. da Silva Andréia F. P. Batista Camila F. Freitas Evandro Bona Maria J. Sereia Wilker Caetano Noburu Hioka Jane M. G. Mikcha Photodynamic antimicrobial chemotherapy (PAC) is an efficient tool for inactivating...
Tue Mar 17, 2020 02:00
Antioxidants, Vol. 9, Pages 243: The Effect of Diet Supplementation with Pomegranate and Bitter Melon on Lipidomic Profile of Serum and Cancerous Tissues of Rats with Mammary Tumours Antioxidants doi: 10.3390/antiox9030243 Authors: Białek Jelińska Białek Lepionka Czerwonka Czauderna The aim of this study was to present overall lipid profile of organisms with ongoing neoplastic process and applied diet supplementation with pomegranate seed oil (PSO) and bitter melon...
Tue Mar 17, 2020 02:00
Antioxidants, Vol. 9, Pages 242: Variations in Anthocyanin Profiles and Antioxidant Activity of 12 Genotypes of Mulberry (Morus spp.) Fruits and Their Changes during Processing Antioxidants doi: 10.3390/antiox9030242 Authors: Inhwan Kim Jihyun Lee Mulberry fruits are known as rich sources of anthocyanins and are consumed in syrup form after the addition of sugar and acid; however, there is little information on the anthocyanin composition and antioxidant activity of mulberries of...
Tue Mar 17, 2020 02:00
Atmosphere, Vol. 11, Pages 295: O3 Sensitivity and Contributions of Different NMHC Sources in O3 Formation at Urban and Suburban Sites in Shanghai Atmosphere doi: 10.3390/atmos11030295 Authors: Lin Wang Duan Fu Ji Cui Jin Lin Hu Ground-level ozone (O3) pollution is still one of the priorities and challenges for air pollution control in the Yangtze River Delta (YRD) region of China. Understanding the relationship of O3 with its precursors and contributions...
Tue Mar 17, 2020 02:00
Beverages, Vol. 6, Pages 19: White Wine Protein Instability: Mechanism, Quality Control and Technological Alternatives for Wine Stabilisation—An Overview Beverages doi: 10.3390/beverages6010019 Authors: Fernanda Cosme Conceição Fernandes Tânia Ribeiro Luís Filipe-Ribeiro Fernando M. Nunes Wine protein instability depends on several factors, but wine grape proteins are the main haze factors, being mainly caused by pathogenesis-related proteins (thaumatin-like proteins and...
Tue Mar 17, 2020 02:00
Biomolecules, Vol. 10, Pages 463: The Human RAD5 Homologs, HLTF and SHPRH, Have Separate Functions in DNA Damage Tolerance Dependent on The DNA Lesion Type Biomolecules doi: 10.3390/biom10030463 Authors: Seelinger Søgaard Otterlei Helicase-like transcription factor (HLTF) and SNF2, histone-linker, PHD and RING finger domain-containing helicase (SHPRH), the two human homologs of yeast Rad5, are believed to have a vital role in DNA damage tolerance (DDT). Here we show that HLTF,...
Tue Mar 17, 2020 02:00
Biomolecules, Vol. 10, Pages 462: p19Arf Exacerbates Cigarette Smoke-Induced Pulmonary Dysfunction Biomolecules doi: 10.3390/biom10030462 Authors: Ryuta Mikawa Tadashi Sato Yohei Suzuki Hario Baskoro Koichiro Kawaguchi Masataka Sugimoto Senescent cells accumulate in tissues during aging or pathological settings. The semi-genetic or pharmacological targeting of senescent cells revealed that cellular senescence underlies many aspects of the aging-associated phenotype and...
Tue Mar 17, 2020 02:00
Biosensors, Vol. 10, Pages 26: The Emergence of Insect Odorant Receptor-Based Biosensors Biosensors doi: 10.3390/bios10030026 Authors: Jonathan D. Bohbot Sefi Vernick The olfactory receptor neurons of insects and vertebrates are gated by odorant receptor (OR) proteins of which several members have been shown to exhibit remarkable sensitivity and selectivity towards volatile organic compounds of significant importance in the fields of medicine, agriculture and public health. Insect...
Tue Mar 17, 2020 02:00
Brain Sciences, Vol. 10, Pages 172: Design Fluency in Children with ADHD and Comorbid Disorders Brain Sciences doi: 10.3390/brainsci10030172 Authors: Anaïs Fournier Bruno Gauthier Marie-Claude Guay Véronique Parent Background: Attention deficit/hyperactivity disorder (ADHD) is often associated with frontal executive impairment in children. Oppositional defiant disorder (ODD) and anxiety disorders (AD) frequently accompany ADHD, but the impact of these comorbid disorders on cognition...
Tue Mar 17, 2020 02:00
Brain Sciences, Vol. 10, Pages 171: Neisseria meningitidis Induced Fatal Waterhouse–Friderichsen Syndrome in a Patient Presenting With Disseminated Intravascular Coagulation and Multiple Organ Failure Brain Sciences doi: 10.3390/brainsci10030171 Authors: Meng-Yu Wu Chien-Sheng Chen Chih-Yi Tsay Giou-Teng Yiang Jian-Yu Ke Po-Chen Lin Neisseria meningitidis-induced acute systemic meningococcal disease is an emergency and a fatal condition that has a high mortality rate....
Tue Mar 17, 2020 02:00
Cancers, Vol. 12, Pages 709: Proteome and Phosphoproteome Changes Associated with Prognosis in Acute Myeloid Leukemia Cancers doi: 10.3390/cancers12030709 Authors: Elise Aasebø Frode S. Berven Sushma Bartaula-Brevik Tomasz Stokowy Randi Hovland Marc Vaudel Stein Ove Døskeland Emmet McCormack Tanveer S. Batth Jesper V. Olsen Øystein Bruserud Frode Selheim Maria Hernandez-Valladares Acute myeloid leukemia (AML) is a hematological cancer that mainly affects...
Tue Mar 17, 2020 02:00
Cancers, Vol. 12, Pages 707: Changes in DNA Damage Response Markers with Treatment in Advanced Ovarian Cancer Cancers doi: 10.3390/cancers12030707 Authors: Paul Kubelac Catherine Genestie Aurelie Auguste Soizick Mesnage Audrey Le Le Formal Patricia Pautier Sebastien Gouy Philippe Morice Enrica Bentivegna Amandine Maulard Julien Adam Patriciu Achimas-Cadariu Alexandra Leary Ovarian cancer (OC) is sensitive to upfront chemotherapy, which is likely attributable...
Tue Mar 17, 2020 02:00
Cancers, Vol. 12, Pages 708: The Microrna-143/145 Cluster in Tumors: A Matter of Where and When Cancers doi: 10.3390/cancers12030708 Authors: Valeria Poli Laura Seclì Lidia Avalle The establishment and spreading of cancer involve the acquirement of many biological functions including resistance to apoptosis, enhanced proliferation and the ability to invade the surrounding tissue, extravasate from the primary site, survive in circulating blood, and finally extravasate and colonize...
Tue Mar 17, 2020 02:00
Cancers, Vol. 12, Pages 705: Current Understanding of RAD52 Functions: Fundamental and Therapeutic Insights Cancers doi: 10.3390/cancers12030705 Authors: Vanesa Gottifredi Lisa Wiesmüller In this Special Issue, we would like to focus on the various functions of the RAD52 helicase-like protein and the current implications of such findings for cancer treatment. Over the last few years, various laboratories have discovered particular activities of mammalian RAD52—both in S...
Tue Mar 17, 2020 02:00
Cancers, Vol. 12, Pages 704: MicroRNAs in Cancer Treatment-Induced Cardiotoxicity Cancers doi: 10.3390/cancers12030704 Authors: Laura Pellegrini Sara Sileno Marco D’Agostino Eleonora Foglio Maria Cristina Florio Vincenzo Guzzanti Matteo Antonio Russo Federica Limana Alessandra Magenta Cancer treatment has made significant progress in the cure of different types of tumors. Nevertheless, its clinical use is limited by unwanted cardiotoxicity. Aside from the conventional...
Tue Mar 17, 2020 02:00
Cancers, Vol. 12, Pages 706: You Have Got a Fast CAR: Chimeric Antigen Receptor NK Cells in Cancer Therapy Cancers doi: 10.3390/cancers12030706 Authors: Aline Pfefferle Nicholas D. Huntington The clinical success stories of chimeric antigen receptor (CAR)-T cell therapy against B-cell malignancies have contributed to immunotherapy being at the forefront of cancer therapy today. Their success has fueled interest in improving CAR constructs, identifying additional antigens to target,...
Tue Mar 17, 2020 02:00
Cells, Vol. 9, Pages 742: Recent Applications of Three Dimensional Printing in Cardiovascular Medicine Cells doi: 10.3390/cells9030742 Authors: Gardin Ferroni Latremouille Chachques Mitrečić Zavan Three dimensional (3D) printing, which consists in the conversion of digital images into a 3D physical model, is a promising and versatile field that, over the last decade, has experienced a rapid development in medicine. Cardiovascular medicine, in particular, is one of...
Tue Mar 17, 2020 02:00
Cells, Vol. 9, Pages 741: O-acetylated Gangliosides as Targets for Cancer Immunotherapy Cells doi: 10.3390/cells9030741 Authors: Cavdarli Delannoy Groux-Degroote O-acetylation of sialic acid residues is one of the main modifications of gangliosides, and modulates ganglioside functions. O-acetylation of gangliosides is dependent on sialyl-O-acetyltransferases and sialyl-O-acetyl-esterase activities. CAS1 Domain-Containing Protein 1 (CASD1) is the only human sialyl-O-acetyltransferases...
Tue Mar 17, 2020 02:00
Cells, Vol. 9, Pages 740: Insulin Resistance Promotes Parkinson’s Disease through Aberrant Expression of α-Synuclein, Mitochondrial Dysfunction, and Deregulation of the Polo-Like Kinase 2 Signaling Cells doi: 10.3390/cells9030740 Authors: Hong Chen Wang Chiu Wu Chao Hu Chau Bamodu : Background: Insulin resistance (IR), considered a hallmark of diabetes at the cellular level, is implicated in pre-diabetes, results in type 2 diabetes, and negatively affects...
Tue Mar 17, 2020 02:00
Cells, Vol. 9, Pages 739: Differentiation of Human Mesenchymal Stem Cells from Wharton’s Jelly Towards Neural Stem Cells Using A Feasible and Repeatable Protocol Cells doi: 10.3390/cells9030739 Authors: Kruminis-Kaszkiel Osowski Bejer-Oleńska Dziekoński Wojtkiewicz The transplantation of neural stem cells (NSCs) capable of regenerating to the cells of the central nervous system (CNS) is a promising strategy in the treatment of CNS diseases and injury. As previous studies...
Tue Mar 17, 2020 02:00
Cells, Vol. 9, Pages 736: Gut–Liver Axis and Inflammasome Activation in Cholangiocyte Pathophysiology Cells doi: 10.3390/cells9030736 Authors: Luca Maroni Elisabetta Ninfole Claudio Pinto Antonio Benedetti Marco Marzioni The Nlrp3 inflammasome is a multiprotein complex activated by a number of bacterial products or danger signals and is involved in the regulation of inflammatory processes through caspase-1 activation. The Nlrp3 is expressed in immune cells but also in hepatocytes...
Tue Mar 17, 2020 02:00
Cells, Vol. 9, Pages 737: Inhibition of Gastrin-Releasing Peptide Attenuates Phosphate-Induced Vascular Calcification Cells doi: 10.3390/cells9030737 Authors: Hyun-Joo Park Yeon Kim Mi-Kyoung Kim Jae Joon Hwang Hyung Joon Kim Soo-Kyung Bae Moon-Kyoung Bae Vascular calcification is the pathological deposition of calcium/phosphate in the vascular system and is closely associated with cardiovascular morbidity and mortality. Here, we investigated the role of gastrin-releasing...
Tue Mar 17, 2020 02:00
Cells, Vol. 9, Pages 738: Function of Torsin AAA+ ATPases in Pseudorabies Virus Nuclear Egress Cells doi: 10.3390/cells9030738 Authors: Julia E. Hölper Barbara G. Klupp G. W. Gant Luxton Kati Franzke Thomas C. Mettenleiter Newly assembled herpesvirus nucleocapsids traverse the intact nuclear envelope by a vesicle-mediated nucleo-cytoplasmic transport for final virion maturation in the cytoplasm. For this, they bud at the inner nuclear membrane resulting in primary enveloped...
Tue Mar 17, 2020 02:00
Cells, Vol. 9, Pages 735: Indirect Role of AQP4b and AQP4d Isoforms in Dynamics of Astrocyte Volume and Orthogonal Arrays of Particles Cells doi: 10.3390/cells9030735 Authors: Marjeta Lisjak Maja Potokar Robert Zorec Jernej Jorgačevski Water channel aquaporin 4 (AQP4) plays a key role in the regulation of water homeostasis in the central nervous system (CNS). It is predominantly expressed in astrocytes lining blood–brain and blood–liquor boundaries. AQP4a...
Tue Mar 17, 2020 02:00
Cells, Vol. 9, Pages 734: Innate Cytokine Induced Early Release of IFNγ and CC Chemokines from Hypoxic Human NK Cells Is Independent of Glucose Cells doi: 10.3390/cells9030734 Authors: Sonia Y. Velásquez Bianca S. Himmelhan Nina Kassner Anna Coulibaly Jutta Schulte Kathrin Brohm Holger A. Lindner Natural killer (NK) cells are among the first innate immune cells to arrive at sites of tissue inflammation and regulate the immune response to infection and tumors by the...
Tue Mar 17, 2020 02:00
Cells, Vol. 9, Pages 733: Impact of Chronic Fetal Hypoxia and Inflammation on Cardiac Pacemaker Cell Development Cells doi: 10.3390/cells9030733 Authors: Martin G. Frasch Dino A. Giussani Chronic fetal hypoxia and infection are examples of adverse conditions during complicated pregnancy, which impact cardiac myogenesis and increase the lifetime risk of heart disease. However, the effects that chronic hypoxic or inflammatory environments exert on cardiac pacemaker cells are poorly...
Tue Mar 17, 2020 02:00
Children, Vol. 7, Pages 21: Effects of a Need-Supportive Motor Skill Intervention on Children’s Motor Skill Competence and Physical Activity Children doi: 10.3390/children7030021 Authors: Joonyoung Lee Tao Zhang Tsz Lun (Alan) Chu Xiangli Gu A need-supportive environment can provide various motivational benefits to impact children’s psychomotor developmental levels. However, very little is known about the effects of need-supportive motor skill intervention on children’s...
Tue Mar 17, 2020 02:00
Diagnostics, Vol. 10, Pages 164: Assessment of DCE Utility for PCa Diagnosis Using PI-RADS v2.1: Effects on Diagnostic Accuracy and Reproducibility Diagnostics doi: 10.3390/diagnostics10030164 Authors: Brancato Di Costanzo Basso Tramontano Puglia Ragozzino Cavaliere The role of dynamic contrast-enhanced-MRI (DCE-MRI) for Prostate Imaging-Reporting and Data System (PI-RADS) scoring is a controversial topic. In this retrospective study, we aimed to measure the...
Tue Mar 17, 2020 02:00
Diagnostics, Vol. 10, Pages 163: Microbiome Profile of Deep Endometriosis Patients: Comparison of Vaginal Fluid, Endometrium and Lesion Diagnostics doi: 10.3390/diagnostics10030163 Authors: Camila Hernandes Paola Silveira Aline Fernanda Rodrigues Sereia Ana Paula Christoff Helen Mendes Luiz Felipe Valter de Oliveira Sergio Podgaec This work aimed to identify and compare the bacterial patterns present in endometriotic lesions, eutopic endometrium and vaginal fluid from...
Tue Mar 17, 2020 02:00
Diagnostics, Vol. 10, Pages 162: Comparison of Night, Day and 24 h Motor Activity Data for the Classification of Depressive Episodes Diagnostics doi: 10.3390/diagnostics10030162 Authors: Julieta G. Rodríguez-Ruiz Carlos E. Galván-Tejada Laura A. Zanella-Calzada José M. Celaya-Padilla Jorge I. Galván-Tejada Hamurabi Gamboa-Rosales Huizilopoztli Luna-García Rafael Magallanes-Quintanar Manuel A. Soto-Murillo Major Depression Disease has been increasing in the last...
Tue Mar 17, 2020 02:00
Diversity, Vol. 12, Pages 104: The Presence of IUCN Red List Tree Species in Dependence of Site Characteristics in the Vietnamese Cat Ba National Park Diversity doi: 10.3390/d12030104 Authors: Van Vien Pham Christian Ammer Peter Annighöfer Rare or endangered tree species are important components of forest ecosystems and play a crucial role in management and conservation. Understanding what influences their presence is critical for managers, conservationists and planners. This study...
Tue Mar 17, 2020 02:00
Environments, Vol. 7, Pages 22: Experimental Procedure for Fifth Generation (5G) Electromagnetic Field (EMF) Measurement and Maximum Power Extrapolation for Human Exposure Assessment Environments doi: 10.3390/environments7030022 Authors: Franci Coltellacci Grillo Pavoncello Aureli Cintoli Migliore The fifth generation (5G) technology has been conceived to cover multiple usage scenarios from enhanced mobile broadband to ultra-reliable low-latency communications...
Tue Mar 17, 2020 02:00
Foods, Vol. 9, Pages 349: Sensory Improvement of a Pea Protein-Based Product Using Microbial Co-Cultures of Lactic Acid Bacteria and Yeasts Foods doi: 10.3390/foods9030349 Authors: El Youssef Bonnarme Fraud Péron Helinck Landaud : Consumer demands for plant-based products have increased in recent years. However, their consumption is still limited due to the presence of off-flavor compounds, primarily beany and green notes, which are mainly associated with the presence...
Tue Mar 17, 2020 02:00
Foods, Vol. 9, Pages 348: Bifidobacterium longum subsp. infantis ATCC 15697 and Goat Milk Oligosaccharides Show Synergism In Vitro as Anti-Infectives against Campylobacter jejuni Foods doi: 10.3390/foods9030348 Authors: Erinn M. Quinn Helen Slattery Dan Walsh Lokesh Joshi Rita M. Hickey Bifidobacteria are known to inhibit, compete with and displace the adhesion of pathogens to human intestinal cells. Previously, we demonstrated that goat milk oligosaccharides (GMO) increased...
Tue Mar 17, 2020 02:00
Foods, Vol. 9, Pages 347: Characterization of Volatile Profiles and Marker Substances by HS-SPME/GC-MS during the Concentration of Coconut Jam Foods doi: 10.3390/foods9030347 Authors: Hao Zhang Haiming Chen Wenzhu Wang Wenxiao Jiao Wenxue Chen Qiuping Zhong Yong-Huan Yun Weijun Chen Characteristic aromas are usually key labels for food products. In this study, the volatile profiles and marker substances of coconut jam during concentration were characterized via sensory...
Tue Mar 17, 2020 02:00
Healthcare, Vol. 8, Pages 61: Current Development Status of Forest Therapy in China Healthcare doi: 10.3390/healthcare8010061 Authors: Zhiyong Zhang Peng Wang Yue Gao Bing Ye As a result of rapid urbanization and urban sprawl, natural ecosystems are shrinking or are fragmented, affecting people’s health and quality of life. Modern people prefer to live in large cities rather than rural areas because of greater convenience and more comfortable living conditions. As...
Tue Mar 17, 2020 02:00
IJERPH, Vol. 17, Pages 1984: Atmospheric Pollution Exposure Increases Disease Activity of Systemic Lupus Erythematosus International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17061984 Authors: Paula Henriques Blaskievicz Ageo Mario Candido Silva Vander Fernandes Osvaldo Borges Pinto Junior Walkiria Shimoya-Bittencourt Silvana Margarida Benevides Ferreira Cristhiane Almeida Leite da Silva Previous studies have shown that high levels of air...
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IJERPH, Vol. 17, Pages 1985: Benchmarking Community Disaster Resilience in Nepal International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17061985 Authors: Sanam K. Aksha Christopher T. Emrich Building disaster resilience is a stated goal of disaster risk reduction programs. Recent research emphasizes a need for a greater understanding of community disaster response and recovery capacity so that communities can absorb shocks and withstand severe conditions...
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