Pathogens, Vol. 9, Pages 221: Free to Circulate: An Update on the Epidemiological Dynamics of Porcine Circovirus 2 (PCV-2) in Italy Reveals the Role of Local Spreading, Wild Populations, and Foreign Countries Pathogens doi: 10.3390/pathogens9030221 Authors: Franzo Tinello Grassi Tucciarone Legnardi Cecchinato Dotto Mondin Martini Pasotto Menandro Drigo Porcine circovirus 2 (PCV-2) is one of the most impactful and widespread pathogens of the...
Pathogens, Vol. 9, Pages 222: Carp Edema Virus and Cyprinid Herpesvirus-3 Coinfection is Associated with Mass Mortality of Koi (Cyprinus carpio haematopterus) in the Republic of Korea Pathogens doi: 10.3390/pathogens9030222 Authors: Kim Giri Kim Kwon Oh Park As koi and common carp gain importance in the Korean fish industry, the need for better diagnosis, prevention, and treatment of associated diseases has increased. In June 2019, the first known case of mass mortality...
Pathogens, Vol. 9, Pages 220: Influenza Virus and Vaccination Pathogens doi: 10.3390/pathogens9030220 Authors: Nogales DeDiego Influenza virus infections represent a serious public health problem causing contagious respiratory disease and substantial morbidity and mortality in humans, resulting in a considerable economic burden worldwide. Notably, the number of deaths due to influenza exceeds that of any other known pathogen. Moreover, influenza infections can differ in their intensity,...
Pathogens, Vol. 9, Pages 219: Combined Amoebicidal Effect of Atorvastatin and Commercial Eye Drops against Acanthamoeba castellanii Neff: In Vitro Assay Based on Mixture Design Pathogens doi: 10.3390/pathogens9030219 Authors: Ines Sifaoui Eulalia Capote Yanes María Reyes-Batlle Rubén L. Rodríguez-Expósito José E. Piñero Jacob Lorenzo-Morales The establishment of an effective therapeutic agent against Acanthamoeba keratitis (AK), remains until present, an issue to be solved...
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Pharmaceuticals, Vol. 13, Pages 47: In Vitro Anti-Prostate Cancer Activity of Two Ebselen Analogues Pharmaceuticals doi: 10.3390/ph13030047 Authors: Katarzyna B. Kaczor-Keller Anna Pawlik Jacek Scianowski Agata Pacuła Magdalena Obieziurska Fabio Marcheggiani Ilenia Cirilli Luca Tiano Jedrzej Antosiewicz Scientific research has been underway for decades in order to develop an effective anticancer drug, and it has become crucial to find a novel and effective chemotherapeutics...
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Pharmaceutics, Vol. 12, Pages 275: Affinity Effects on the Release of Non-conventional Antifibrotics from Polymer Depots Pharmaceutics doi: 10.3390/pharmaceutics12030275 Authors: Rohner Nguyen von Recum For many chronic fibrotic conditions, there is a need for local, sustained antifibrotic drug delivery. A recent trend in the pharmaceutical industry is the repurposing of approved drugs. This paper investigates drugs that are classically used for anthelmintic activity (pyrvinium...
Pharmaceutics, Vol. 12, Pages 274: Crosslinked Hyaluronan Electrospun Nanofibers for Ferulic Acid Ocular Delivery Pharmaceutics doi: 10.3390/pharmaceutics12030274 Authors: Maria Aurora Grimaudo Angel Concheiro Carmen Alvarez-Lorenzo Electrospun nanofibers are gaining interest as ocular drug delivery platforms that may adapt to the eye surface and provide sustained release. The aim of this work was to design an innovative ophthalmic insert composed of hyaluronan (HA) nanofibers...
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Pharmacy, Vol. 8, Pages 42: Wage Premiums as a Means to Evaluate the Labor Market for Pharmacy Technicians in the United States: 1997–2018 Pharmacy doi: 10.3390/pharmacy8010042 Authors: David P. Zgarrick Tatiana Bujnoch Shane P. Desselle Pharmacy technicians are integral members of the health care team, assisting pharmacists and other health professionals in assuring safe and effective medication use. To date, evaluation of the labor market for pharmacy technicians has been limited,...
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Plants, Vol. 9, Pages 372: AgNO3 Sterilizes Grains of Barley (Hordeum vulgare) without Inhibiting Germination—A Necessary Tool for Plant–Microbiome Research Plants doi: 10.3390/plants9030372 Authors: Munkager Vestergård Priemé Altenburger Visser Johansen Ekelund To understand and manipulate the interactions between plants and microorganisms, sterile seeds are a necessity. The seed microbiome (inside and surface microorganisms) is unknown for most plant species...
Plants, Vol. 9, Pages 371: Phytochemical Profiles and Antioxidant Activity of Grasses Used in South African Traditional Medicine Plants doi: 10.3390/plants9030371 Authors: Fikisiwe Gebashe Adeyemi O. Aremu Jiri Gruz Jeffrey F. Finnie Johannes Van Staden Grasses are a valuable group of monocotyledonous plants, used as nourishing foods and as remedies against diseases for both humans and livestock. Phytochemical profiles of 13 medicinal grasses were quantified, using spectrophotometric...
Plants, Vol. 9, Pages 370: Tetraploid Induction by Colchicine Treatment and Crossing with a Diploid Reveals Less-Seeded Fruit Production in Pointed Gourd (Trichosanthes dioica Roxb.) Plants doi: 10.3390/plants9030370 Authors: Jahidul Hassan Ikuo Miyajima Yukio Ozaki Yuki Mizunoe Kaori Sakai Wasimullah Zaland Pointed gourd (Trichosanthes dioica Roxb.) (2n = 2x = 22) is a dioecious cucurbit vegetable and green fruit that is edible after cooking. Consumers prefer to consume...
Plants, Vol. 9, Pages 368: Non-Destructive Detection of Tea Leaf Chlorophyll Content Using Hyperspectral Reflectance and Machine Learning Algorithms Plants doi: 10.3390/plants9030368 Authors: Rei Sonobe Yuhei Hirono Ayako Oi Tea trees are kept in shaded locations to increase their chlorophyll content, which influences green tea quality. Therefore, monitoring change in chlorophyll content under low light conditions is important for managing tea trees and producing high-quality green...
Plants, Vol. 9, Pages 369: Impact of Spontaneous Haploid Genome Doubling in Maize Breeding Plants doi: 10.3390/plants9030369 Authors: Boerman Frei Lübberstedt Doubled haploid (DH) technology has changed the maize-breeding landscape in recent years. Traditionally, DH production requires the use of chemical doubling agents to induce haploid genome doubling and, subsequently, male fertility. These chemicals can be harmful to humans and the plants themselves, and typically result...
Plants, Vol. 9, Pages 367: The Chloroplast Ribonucleoprotein CP33B Quantitatively Binds the psbA mRNA Plants doi: 10.3390/plants9030367 Authors: Marlene Teubner Benjamin Lenzen Lucas Bernal Espenberger Janina Fuss Jörg Nickelsen Kirsten Krause Hannes Ruwe Christian Schmitz-Linneweber Chloroplast RNAs are stabilized and processed by a multitude of nuclear-encoded RNA-binding proteins, often in response to external stimuli like light and temperature. A particularly...
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Plasma, Vol. 3, Pages 27-37: Taylor State Merging at SSX: Experiment and Simulation Plasma doi: 10.3390/plasma3010004 Authors: Michael Brown Kaitlin Gelber Matiwos Mebratu We describe experiments and simulations of dynamical merging with two Taylor state plasmas in a Swarthmore Spheromak Experiment (SSX) device. Taylor states are formed by magnetized plasma guns at opposite ends of the device. We performed experiments with Taylor states of both senses of magnetic helicity (right-handed...
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Religions, Vol. 11, Pages 134: The Idea of the Anavatapta Lake in India and Its Adoption in East Asia Religions doi: 10.3390/rel11030134 Authors: Yang Gao This article centers around the Anavatapta Lake. In East Asian pictorialization of worldview, Maps of Mt. Sumeru, which depict the mountain at the core of the world, are often paired with Maps of India, in which the Anavatapta Lake occupies a significant place. When the concept of the Anavatapta Lake was transmitted from India to China...
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Resources, Vol. 9, Pages 34: Life Cycle Assessment of the Closed-Loop Recycling of Used Disposable Diapers Resources doi: 10.3390/resources9030034 Authors: Norihiro Itsubo Mitsuhiro Wada Shigeo Imai Akira Myoga Naoki Makino Koichi Shobatake In Japan, approximately 23.5 billion paper diapers are produced annually (total of diapers for infants and adults produced in 2018). The majority of used paper diapers are disposed of through incineration; in certain regions, some paper...
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Risks, Vol. 8, Pages 30: Gerber–Shiu Function in a Class of Delayed and Perturbed Risk Model with Dependence Risks doi: 10.3390/risks8010030 Authors: Franck Adékambi Essodina Takouda This paper considers the risk model perturbed by a diffusion process with a time delay in the arrival of the first two claims and takes into account dependence between claim amounts and the claim inter-occurrence times. Assuming that the time arrival of the first claim follows a generalized mixed equilibrium...
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Robotics, Vol. 9, Pages 16: A Review on Design of Upper Limb Exoskeletons Robotics doi: 10.3390/robotics9010016 Authors: Muhammad Ahsan Gull Shaoping Bai Thomas Bak Exoskeleton robotics has ushered in a new era of modern neuromuscular rehabilitation engineering and assistive technology research. The technology promises to improve the upper-limb functionalities required for performing activities of daily living. The exoskeleton technology is evolving quickly but still needs interdisciplinary...
Robotics, Vol. 9, Pages 15: Artistic Robotic Painting Using the Palette Knife Technique Robotics doi: 10.3390/robotics9010015 Authors: Andrea Beltramello Lorenzo Scalera Stefano Seriani Paolo Gallina This paper presents a novel robotic painting system able to create artworks using the palette knife technique. The implementation of this method with a robotic system is particularly challenging, since the robot needs to precisely manipulate the palette knife to pick up and release...
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Societies, Vol. 10, Pages 26: Tackling Complex Social Challenges within Neoliberal Constraints: The Context Shaping ‘Intellectual Quality of Life’ (iQoL) in a Canadian University Context Societies doi: 10.3390/soc10010026 Authors: Suzanne Huot Jocelyn McKay Skye Barbic Alison Wylie Dominique Weis Sarah Bean Sherman Liisa Holsti The contemporary academic environment in Canada has undergone reorganization based on neoliberal principles, and has increased attention focused...
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Technologies, Vol. 8, Pages 17: ExerTrack—Towards Smart Surfaces to Track Exercises Technologies doi: 10.3390/technologies8010017 Authors: Biying Fu Lennart Jarms Florian Kirchbuchner Arjan Kuijper The concept of the quantified self has gained popularity in recent years with the hype of miniaturized gadgets to monitor vital fitness levels. Smartwatches or smartphone apps and other fitness trackers are overwhelming the market. Most aerobic exercises such as walking, running,...
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Toxins, Vol. 12, Pages 189: Parathyroid Hormone: A Uremic Toxin Toxins doi: 10.3390/toxins12030189 Authors: Duque Elias Moysés Parathyroid hormone (PTH) has an important role in the maintenance of serum calcium levels. It activates renal 1α-hydroxylase and increases the synthesis of the active form of vitamin D (1,25[OH]2D3). PTH promotes calcium release from the bone and enhances tubular calcium resorption through direct action on these sites. Hallmarks of secondary...
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Vaccines, Vol. 8, Pages 131: Immunologic Dose-Response to Adenovirus-Vectored Vaccines in Animals and Humans: A Systematic Review of Dose-Response Studies of Replication Incompetent Adenoviral Vaccine Vectors when Given via an Intramuscular or Subcutaneous Route Vaccines doi: 10.3390/vaccines8010131 Authors: Afrough Rhodes Evans White Benest Optimal vaccine dosing is important to ensure the greatest protection and safety. Analysis of dose-response data, from previous...
Vaccines, Vol. 8, Pages 132: Development of Next Generation Streptococcus pneumoniae Vaccines Conferring Broad Protection Vaccines doi: 10.3390/vaccines8010132 Authors: Malihe Masomian Zuleeza Ahmad Lai Ti Gew Chit Laa Poh Streptococcus pneumoniae is a major pathogen causing pneumonia with over 2 million deaths annually, especially in young children and the elderly. To date, at least 98 different pneumococcal capsular serotypes have been identified. Currently, the vaccines for...
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Viruses, Vol. 12, Pages 324: The Impact of Human Genetic Polymorphisms on Rotavirus Susceptibility, Epidemiology, and Vaccine Take Viruses doi: 10.3390/v12030324 Authors: Sharma Hagbom Svensson Nordgren Innate resistance to viral infections can be attributed to mutations in genes involved in the immune response, or to the receptor/ligand. A remarkable example of the latter is the recently described Mendelian trait resistance to clinically important and globally predominating...
Viruses, Vol. 12, Pages 325: Coxsackievirus B3 Infection of Human Neural Progenitor Cells Results in Distinct Expression Patterns of Innate Immune Genes Viruses doi: 10.3390/v12030325 Authors: Oh Gim Lee Park Shin Coxsackievirus B3 (CVB3), a member of Picornaviridae family, is an important human pathogen that causes a wide range of diseases, including myocarditis, pancreatitis, and meningitis. Although CVB3 has been well demonstrated to target murine neural progenitor...
Viruses, Vol. 12, Pages 323: A Novel Hepe-Like Virus from Farmed Giant Freshwater Prawn Macrobrachium rosenbergii Viruses doi: 10.3390/v12030323 Authors: Xuan Dong Tao Hu Qingyuan Liu Chen Li Yani Sun Yiting Wang Weifeng Shi Qin Zhao Jie Huang The family Hepeviridae includes several positive-stranded RNA viruses, which infect a wide range of mammalian species, chicken, and trout. However, few hepatitis E viruses (HEVs) have been characterized from invertebrates....
Viruses, Vol. 12, Pages 322: Honey Bee Queens and Virus Infections Viruses doi: 10.3390/v12030322 Authors: Amiri Strand Tarpy Rueppell The honey bee queen is the central hub of a colony to produce eggs and release pheromones to maintain social cohesion. Among many environmental stresses, viruses are a major concern to compromise the queen’s health and reproductive vigor. Viruses have evolved numerous strategies to infect queens either via vertical transmission...
Viruses, Vol. 12, Pages 321: Foodborne Transmission and Clinical Symptoms of Honey Bee Viruses in Ants Lasius spp. Viruses doi: 10.3390/v12030321 Authors: Daniel Schläppi Nor Chejanovsky Orlando Yañez Peter Neumann Emerging infectious diseases are often the products of host shifts, where a pathogen jumps from its original host to a novel species. Viruses in particular cross species barriers frequently. Acute bee paralysis virus (ABPV) and deformed wing virus (DWV) are viruses...
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Water, Vol. 12, Pages 848: Land Cover and Water Quality Patterns in an Urban River: A Case Study of River Medlock, Greater Manchester, UK Water doi: 10.3390/w12030848 Authors: Medupin Bark Owusu Urban river catchments face multiple water quality challenges that threaten the biodiversity of riverine habitats and the flow of ecosystem services. We examined two water quality challenges, runoff from increasingly impervious land covers and effluent from combined sewer overflows within...
Water, Vol. 12, Pages 847: Organizational Water Footprint to Support Decision Making: A Case Study for a German Technological Solutions Provider for the Plumbing Industry Water doi: 10.3390/w12030847 Authors: Forin Gossmann Weis Thylmann Bunsen Berger Finkbeiner With water scarcity representing an increasing threat to humans, the environment and the economy, companies are interested in exploring how their operations and supply chains affect water resources globally....
Water, Vol. 12, Pages 849: Seasonal and Diurnal Variations in the Priestley–Taylor Coefficient for a Large Ephemeral Lake Water doi: 10.3390/w12030849 Authors: Gan Liu Pan Zhao Li Wang The Priestley–Taylor equation (PTE) is widely used with its sole parameter (α) set as 1.26 for estimating the evapotranspiration (ET) of water bodies. However, variations in α may be large for ephemeral lakes. Poyang Lake, which is the largest freshwater...
Water, Vol. 12, Pages 845: Effect of Wave, Current, and Lutocline on Sediment Resuspension in Yellow River Delta-Front Water doi: 10.3390/w12030845 Authors: Bowen Li Yonggang Jia J. Paul Liu Xiaolei Liu Zhenhao Wang Historically, the Yellow River in China discharges > 1 × 109 ton/yr sediment to the sea, and has formed a large delta in the western Bohai Sea. Its river mouth is characterized by an extremely high suspended sediment concentration (SSC), up to...
Water, Vol. 12, Pages 844: Variation of Coefficient of Friction and Friction Head Losses Along a Pipe with Multiple Outlets Water doi: 10.3390/w12030844 Authors: Wissam H. Alawee Yousef A. Almolhem Badronnisa Yusuf Thamer A. Mohammad Hayder A. Dhahad The flow in a pipe having multiple outlets is considered as an advanced problem in hydraulic engineering; many discrepancies were found in the literature, in addition to the lack of experimental and field studies. The main goal...
Water, Vol. 12, Pages 846: Effects of Rainfall Spatial Distribution on the Relationship between Rainfall Spatiotemporal Resolution and Runoff Prediction Accuracy Water doi: 10.3390/w12030846 Authors: Changhwan Kim Dae-Hong Kim We studied how rainfall spatial distribution affects the relationship between rainfall spatiotemporal resolution and runoff prediction accuracy under real field conditions. We gathered radar rainfall and discharge data for three rainfall events. These rainfall-runoff...
Water, Vol. 12, Pages 843: Hydraulic Properties of a Cultivated Soil in Temperate Continental Climate Determined by Mini Disk Infiltrometer Water doi: 10.3390/w12030843 Authors: Kamila Báťková Markéta Miháliková Svatopluk Matula Hydraulic conductivity at and near saturation (Ks and K(h)) are among the most important characteristics defining water behavior in soil. Characterization of possibilities, advantages and limitations of the Mini Disk infiltrometer (MDI) for Ks and K(h)...
Water, Vol. 12, Pages 842: Climatic Variability and Periodicity for Upstream Sub-Basins of the Yangtze River, China Water doi: 10.3390/w12030842 Authors: Naveed Ahmed Genxu Wang Martijn J. Booij Adeyeri Oluwafemi Muhammad Zia-ur-Rahman Hashmi Shahid Ali Sarfraz Munir The headwaters of the Yangtze River are located on the Qinghai Tibetan Plateau, which is affected by climate change. Here, treamflow trends for Tuotuohe and Zhimenda sub-basins and relations to temperature...
Water, Vol. 12, Pages 841: Nonlinear Autoregressive Neural Networks to Predict Hydraulic Fracturing Fluid Leakage into Shallow Groundwater Water doi: 10.3390/w12030841 Authors: Reza Taherdangkoo Alexandru Tatomir Mohammad Taherdangkoo Pengxiang Qiu Martin Sauter Hydraulic fracturing of horizontal wells is an essential technology for the exploitation of unconventional resources, but led to environmental concerns. Fracturing fluid upward migration from deep gas reservoirs along...
Water, Vol. 12, Pages 840: Impact of Precipitation Pre-Processing Methods on Hydrological Model Performance using High-Resolution Gridded Dataset Water doi: 10.3390/w12030840 Authors: Salam A. Abbas Yunqing Xuan Effective representation of precipitation inputs is one of the essential components in hydrological model structures, especially when gauge measurements for the modelled catchment are sparse. Assessment of the impact of precipitation pre-processing is often nontrivial as precipitation...
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