IJMS, Vol. 21, Pages 2062: Candidate Genes for Freezing and Drought Tolerance Selected on the Basis of Proteome Analysis in Doubled Haploid Lines of Barley International Journal of Molecular Sciences doi: 10.3390/ijms21062062 Authors: Wójcik-Jagła Rapacz Dubas Krzewska Kopeć Nowicka Ostrowska Malaga Żur Plant tolerance to environmental stress is determined by a very complicated network composed of many intra- and extracellular factors. The aim of this...
Tue Mar 17, 2020 02:00
IJMS, Vol. 21, Pages 2065: The beta Subunit of Nascent Polypeptide Associated Complex Plays A Role in Flowers and Siliques Development of Arabidopsis thaliana International Journal of Molecular Sciences doi: 10.3390/ijms21062065 Authors: Fíla Klodová Potěšil Juříček Šesták Zdráhal Honys The nascent polypeptide-associated (NAC) complex was described in yeast as a heterodimer composed of two subunits, α and β, and was shown to bind to the nascent...
Tue Mar 17, 2020 02:00
IJMS, Vol. 21, Pages 2060: Combined Chibby and β-Catenin Predicts Clinical Outcomes in Patients with Hepatocellular Carcinoma International Journal of Molecular Sciences doi: 10.3390/ijms21062060 Authors: Tsai Huang Wei Liu Lin Yi Lin Wang Chu Hsiao Hu Tai Chibby is an antagonist of β-catenin and is considered a potential tumor suppressor protein, but the role of Chibby in hepatocellular carcinoma (HCC) has not been characterized....
Tue Mar 17, 2020 02:00
IJMS, Vol. 21, Pages 2061: PPARs as Metabolic Regulators in the Liver: Lessons from Liver-Specific PPAR-Null Mice International Journal of Molecular Sciences doi: 10.3390/ijms21062061 Authors: Wang Nakajima Gonzalez Tanaka Peroxisome proliferator-activated receptor (PPAR) α, β/δ, and γ modulate lipid homeostasis. PPARα regulates lipid metabolism in the liver, the organ that largely controls whole-body nutrient/energy homeostasis,...
Tue Mar 17, 2020 02:00
IJMS, Vol. 21, Pages 2059: Benzothiazolyl Ureas are Low Micromolar and Uncompetitive Inhibitors of 17β-HSD10 with Implications to Alzheimer’s Disease Treatment International Journal of Molecular Sciences doi: 10.3390/ijms21062059 Authors: Monika Schmidt Ondrej Benek Lucie Vinklarova Martina Hrabinova Lucie Zemanova Matej Chribek Vendula Kralova Lukas Hroch Rafael Dolezal Antonin Lycka Lukas Prchal Daniel Jun Laura Aitken Frank Gunn-Moore Kamil Kuca...
Tue Mar 17, 2020 02:00
IJMS, Vol. 21, Pages 2058: Thiopurine Derivative-Induced Fpg/Nei DNA Glycosylase Inhibition: Structural, Dynamic and Functional Insights International Journal of Molecular Sciences doi: 10.3390/ijms21062058 Authors: Charlotte Rieux Stéphane Goffinont Franck Coste Zahira Tber Julien Cros Vincent Roy Martine Guérin Virginie Gaudon Stéphane Bourg Artur Biela Vincent Aucagne Luigi Agrofoglio Norbert Garnier Bertrand Castaing DNA glycosylases are emerging...
Tue Mar 17, 2020 02:00
IJMS, Vol. 21, Pages 2057: Identification of Telocytes in the Pancreas of Turtles—A role in Cellular Communication International Journal of Molecular Sciences doi: 10.3390/ijms21062057 Authors: Noor Samad Gandahi Botao Ding Yonghong Shi Xuebing Bai Jameel Ahmed Gandahi Waseem Ali Vistro Qiusheng Chen Ping Yang The existence of telocytes (TCs) has not yet been established in the pancreases of aquatic reptiles. Here, we report TCs in the exocrine pancreas of Pelodiscus...
Tue Mar 17, 2020 02:00
IJMS, Vol. 21, Pages 2056: Soluble Epoxide Hydrolase 2 Expression Is Elevated in Obese Humans and Decreased by Physical Activity International Journal of Molecular Sciences doi: 10.3390/ijms21062056 Authors: Abdelkrim Khadir Sina Kavalakatt Dhanya Madhu Preethi Cherian Fahd Al-Mulla Jehad Abubaker Ali Tiss Epoxide hydrolase 2 (EPHX2) is an emerging therapeutic target in several immunometabolic disorders. EPHX2 metabolizes anti-inflammatory epoxyeicosatrienoic acids...
Tue Mar 17, 2020 02:00
IJMS, Vol. 21, Pages 2054: A Retrospective on eIF2A—and Not the Alpha Subunit of eIF2 International Journal of Molecular Sciences doi: 10.3390/ijms21062054 Authors: Anton A. Komar William C. Merrick Initiation of protein synthesis in eukaryotes is a complex process requiring more than 12 different initiation factors, comprising over 30 polypeptide chains. The functions of many of these factors have been established in great detail; however, the precise role of some of them and their...
Tue Mar 17, 2020 02:00
IJMS, Vol. 21, Pages 2055: Mechanosensitive Aspects of Cell Biology in Manual Scar Therapy for Deep Dermal Defects International Journal of Molecular Sciences doi: 10.3390/ijms21062055 Authors: Thomas Koller Deep dermal defects can result from burns, necrotizing fasciitis and severe soft tissue trauma. Physiological scar restriction during wound healing becomes increasingly relevant in proportion to the affected area. This massively restricts the general mobility of patients. External...
Tue Mar 17, 2020 02:00
IJMS, Vol. 21, Pages 2052: Structure and Bioactive Properties of Novel Textile Dyes Synthesised by Fungal Laccase International Journal of Molecular Sciences doi: 10.3390/ijms21062052 Authors: Polak Wlizło Pogni Petricci Grąz Szałapata Osińska-Jaroszuk Kapral-Piotrowska Pawlikowska-Pawlęga Jarosz-Wilkołazka Novel sustainable processes involving oxidative enzymatic catalysts are considered as an alternative for classical organic chemistry. The unique...
Tue Mar 17, 2020 02:00
IJMS, Vol. 21, Pages 2053: Mechanistic Chromatographic Column Characterization for the Analysis of Flavonoids Using Quantitative Structure-Retention Relationships Based on Density Functional Theory International Journal of Molecular Sciences doi: 10.3390/ijms21062053 Authors: Buszewski Žuvela Sagandykova Walczak-Skierska Pomastowski David Wong This work aimed to unravel the retention mechanisms of 30 structurally different flavonoids separated on three chromatographic...
Tue Mar 17, 2020 02:00
IJMS, Vol. 21, Pages 2050: Transcriptomic and Network Analysis Identifies Shared and Unique Pathways across Dementia Spectrum Disorders International Journal of Molecular Sciences doi: 10.3390/ijms21062050 Authors: Jose A. Santiago Virginie Bottero Judith A. Potashkin Background: Dementia is a growing public health concern with an estimated prevalence of 50 million people worldwide. Alzheimer’s disease (AD) and vascular and frontotemporal dementias (VaD, FTD), share many...
Tue Mar 17, 2020 02:00
IJMS, Vol. 21, Pages 2048: Indole-3-Carbinol Derivative DIM Mitigates Carbon Tetrachloride-Induced Acute Liver Injury in Mice by Inhibiting Inflammatory Response, Apoptosis and Regulating Oxidative Stress International Journal of Molecular Sciences doi: 10.3390/ijms21062048 Authors: Suvesh Munakarmi Lokendra Chand Hyun Beak Shin Kyu Yun Jang Yeon Jun Jeong 3,3′-Diindolylmethane (DIM), a metabolic product of indole-3-carbinol extracted from cruciferous vegetables...
Tue Mar 17, 2020 02:00
IJMS, Vol. 21, Pages 2047: Effect of Streptozotocin-Inducted Diabetes on the Pathophysiology of Enteric Neurons in the Small Intestine Based on the Porcine Diabetes Model International Journal of Molecular Sciences doi: 10.3390/ijms21062047 Authors: Michał Bulc Jarosław Całka Katarzyna Palus Hyperglycemia is one of the main causes of diabetes complications. Gastrointestinal (GI) disturbances are one of the most frequent complications during diabetes. The porcine digestive tract...
Tue Mar 17, 2020 02:00
IJMS, Vol. 21, Pages 2049: Cryptides Identified in Human Apolipoprotein B as New Weapons to Fight Antibiotic Resistance in Cystic Fibrosis Disease International Journal of Molecular Sciences doi: 10.3390/ijms21062049 Authors: Rosa Gaglione Angela Cesaro Eliana Dell’Olmo Rocco Di Girolamo Luca Tartaglione Elio Pizzo Angela Arciello Chronic respiratory infections are the main cause of morbidity and mortality in cystic fibrosis (CF) patients, and are characterized by the...
Tue Mar 17, 2020 02:00
IJMS, Vol. 21, Pages 2051: On-treatment Serum Mac-2 Binding Protein Glycosylation Isomer (M2BPGi) Level and Risk of Hepatocellular Carcinoma Development in Patients with Chronic Hepatitis B during Nucleot(s)ide Analogue Therapy International Journal of Molecular Sciences doi: 10.3390/ijms21062051 Authors: Ayato Murata Nozomi Amano Sho Sato Hironori Tsuzura Ko Tomishima Shunsuke Sato Kohei Matsumoto Yuji Shimada Katsuyori Iijima Takuya Genda We aimed to analyze...
Tue Mar 17, 2020 02:00
IJMS, Vol. 21, Pages 2043: Genome-Wide Association Mapping for Heat Stress Responsive Traits in Field Pea International Journal of Molecular Sciences doi: 10.3390/ijms21062043 Authors: Tafesse Gali Lachagari Bueckert Warkentin Environmental stress hampers pea productivity. To understand the genetic basis of heat resistance, a genome-wide association study (GWAS) was conducted on six stress responsive traits of physiological and agronomic importance in pea, with an objective...
Tue Mar 17, 2020 02:00
IJMS, Vol. 21, Pages 2046: Generation of a Model to Predict Differentiation and Migration of Lymphocyte Subsets under Homeostatic and CNS Autoinflammatory Conditions International Journal of Molecular Sciences doi: 10.3390/ijms21062046 Authors: Catharina C. Gross Marc Pawlitzki Andreas Schulte-Mecklenbeck Leoni Rolfes Tobias Ruck Petra Hundehege Heinz Wiendl Michael Herty Sven G. Meuth The central nervous system (CNS) is an immune-privileged compartment that is...
Tue Mar 17, 2020 02:00
IJMS, Vol. 21, Pages 2045: Abberant Immunoglobulin G Glycosylation in Rheumatoid Arthritis by LTQ-ESI-MS International Journal of Molecular Sciences doi: 10.3390/ijms21062045 Authors: Zhipeng Su Qing Xie Yanping Wang Yunsen Li Aberrant glycosylation has been observed in many autoimmune diseases. For example, aberrant glycosylation of immunoglobulin G (IgG) has been implicated in rheumatoid arthritis (RA) pathogenesis. The aim of this study is to investigate IgG glycosylation...
Tue Mar 17, 2020 02:00
IJMS, Vol. 21, Pages 2044: Effects of Long-Chain Fatty Acyl-CoA Synthetase 1 on Diglyceride Synthesis and Arachidonic Acid Metabolism in Sheep Adipocytes International Journal of Molecular Sciences doi: 10.3390/ijms21062044 Authors: Yang Cao Sutian Wang Shunqi Liu Yanli Wang Haiguo Jin Huihai Ma Xiaotong Luo Yang Cao Zhengxing Lian Long-chain fatty acyl-CoA synthetase (ACSLs) is an essential enzyme for the synthesis of fatty acyl-CoA. ACSL1 plays a key role in...
Tue Mar 17, 2020 02:00
IJMS, Vol. 21, Pages 2042: Abscisic Acid and Jasmonate Metabolisms Are Jointly Regulated During Senescence in Roots and Leaves of Populus trichocarpa International Journal of Molecular Sciences doi: 10.3390/ijms21062042 Authors: Natalia Wojciechowska Emilia Wilmowicz Katarzyna Marzec-Schmidt Agnieszka Ludwików Agnieszka Bagniewska-Zadworna Plant senescence is a highly regulated process that allows nutrients to be mobilized from dying tissues to other organs. Despite that...
Tue Mar 17, 2020 02:00
IJMS, Vol. 21, Pages 2041: UbcH10 a Major Actor in Cancerogenesis and a Potential Tool for Diagnosis and Therapy International Journal of Molecular Sciences doi: 10.3390/ijms21062041 Authors: Ivan Presta Fabiana Novellino Annalidia Donato Domenico La Torre Caterina Palleria Emilio Russo Natalia Malara Giuseppe Donato Malignant transformation is a multistep process in which several molecular entities become dysregulated and result in dysfunction in the regulation...
Tue Mar 17, 2020 02:00
JCM, Vol. 9, Pages 818: Clinical, Immunological, and Functional Characterization of Six Patients with Very High IgM Levels Journal of Clinical Medicine doi: 10.3390/jcm9030818 Authors: Vera Gallo Emilia Cirillo Rosaria Prencipe Alessio Lepore Luigi Del Vecchio Giulia Scalia Vincenzo Martinelli Gigliola Di Matteo Carol Saunders Anne Durandy Viviana Moschese Antonio Leonardi Giuliana Giardino Claudio Pignata Very high IgM levels represent the hallmark...
Tue Mar 17, 2020 02:00
JCM, Vol. 9, Pages 816: Twenty Years of Cerebral Ultrasound Perfusion Imaging—Is the Best yet to Come? Journal of Clinical Medicine doi: 10.3390/jcm9030816 Authors: Jens Eyding Christian Fung Wolf-Dirk Niesen Christos Krogias Over the past 20 years, ultrasonic cerebral perfusion imaging (UPI) has been introduced and validated applying different data acquisition and processing approaches. Clinical data were collected mainly in acute stroke patients. Some efforts were undertaken...
Tue Mar 17, 2020 02:00
JCM, Vol. 9, Pages 817: Evaluation of the Dimensional Accuracy of 3D-Printed Anatomical Mandibular Models Using FFF, SLA, SLS, MJ, and BJ Printing Technology Journal of Clinical Medicine doi: 10.3390/jcm9030817 Authors: Bilal Msallem Neha Sharma Shuaishuai Cao Florian S. Halbeisen Hans-Florian Zeilhofer Florian M. Thieringer With the rapid progression of additive manufacturing and the emergence of new 3D printing technologies, accuracy assessment is mostly being performed...
Tue Mar 17, 2020 02:00
JCM, Vol. 9, Pages 815: Bedside 3D Visualization of Lymphatic Vessels with a Handheld Multispectral Optoacoustic Tomography Device Journal of Clinical Medicine doi: 10.3390/jcm9030815 Authors: Guido Giacalone Takumi Yamamoto Florence Belva Akitatsu Hayashi Identification of lymphatics by Indocyanine Green (ICG) lymphography in patients with severe lymphedema is limited due to the overlying dermal backflow. Nor can the method detect deep and/or small vessels. Multispectral optoacoustic...
Tue Mar 17, 2020 02:00
JCM, Vol. 9, Pages 814: Assessing the Implementation of Pharmacogenomic Panel-Testing in Primary Care in the Netherlands Utilizing a Theoretical Framework Journal of Clinical Medicine doi: 10.3390/jcm9030814 Authors: Cathelijne H. van der Wouden Ellen Paasman Martina Teichert Matty R. Crone Henk-Jan Guchelaar Jesse J. Swen Despite overcoming many implementation barriers, pharmacogenomic (PGx) panel-testing is not routine practice in the Netherlands. Therefore, we aim to...
Tue Mar 17, 2020 02:00
JCM, Vol. 9, Pages 812: Research Insights on Neural Effects of Auditory Deprivation and Restoration in Unilateral Hearing Loss: A Systematic Review Journal of Clinical Medicine doi: 10.3390/jcm9030812 Authors: Jolijn Vanderauwera Elisabeth Hellemans Nicolas Verhaert Neuroplasticity following bilateral deafness and auditory restoration has been repeatedly investigated. In clinical practice, however, a significant number of patients present a severe-to-profound unilateral hearing...
Tue Mar 17, 2020 02:00
JCM, Vol. 9, Pages 813: Special Issue “Diabetic Nephropathy: Diagnosis, Prevention and Treatment” Journal of Clinical Medicine doi: 10.3390/jcm9030813 Authors: Marta Ruiz-Ortega Raul R. Rodrigues-Diez Carolina Lavoz Sandra Rayego-Mateos Diabetic nephropathy (DN) is the main cause of end-stage renal disease. DN is a complex disease mediated by genetic and environmental factors, and many cellular and molecular mechanisms are involved in renal damage in diabetes. There are no biomarkers...
Tue Mar 17, 2020 02:00
JFB, Vol. 11, Pages 19: Optimization of Polydopamine Coatings onto Poly–ε–Caprolactone Electrospun Fibers for the Fabrication of Bio-Electroconductive Interfaces Journal of Functional Biomaterials doi: 10.3390/jfb11010019 Authors: Simona Zuppolini Iriczalli Cruz-Maya Vincenzo Guarino Anna Borriello In recent years, mussel adhesive proteins have attracted much attention because they can form strong adhesive interface interactions with various substrates in a wet environment....
Tue Mar 17, 2020 02:00
JFMK, Vol. 5, Pages 21: Session RPE breakpoints Corresponding to Intensity Thresholds in Elite Open Water Swimmers Journal of Functional Morphology and Kinesiology doi: 10.3390/jfmk5010021 Authors: Ieno Baldassarre Quagliarotti Bonifazi Piacentini This study aims to assess the correspondence between session rating of perceived exertion (sRPE) breakpoints with both the first lactate threshold (LT1) and the second lactate threshold (LT2) in elite open water swimmers (OWS)....
Tue Mar 17, 2020 02:00
J. Imaging, Vol. 6, Pages 12: Food Intake Actions Detection: An Improved Algorithm Toward Real-Time Analysis Journal of Imaging doi: 10.3390/jimaging6030012 Authors: Ennio Gambi Manola Ricciuti Adelmo De Santis With the increase in life expectancy, one of the most important topic for scientific research, especially for the elderly, is good nutrition. In particular, with an advanced age and health issues because disorders such as Alzheimer and dementia, monitoring the subjects’...
Tue Mar 17, 2020 02:00
JPM, Vol. 10, Pages 18: Dysmorphology in the Era of Genomic Diagnosis Journal of Personalized Medicine doi: 10.3390/jpm10010018 Authors: Hurst Robin Genetic and genomic testing technologies have expanded beyond levels of diagnostic capability that were unimaginable even a few years ago. While this has significantly benefited clinicians in their care of patients and families, it has also altered how geneticists evaluate patients. One immediate example is the role of the dysmorphologic...
Tue Mar 17, 2020 02:00
Life, Vol. 10, Pages 25: Spectrum of Light as a Determinant of Plant Functioning: A Historical Perspective Life doi: 10.3390/life10030025 Authors: Oxana S. Ptushenko Vasily V. Ptushenko Alexei E. Solovchenko The significance of the spectral composition of light for growth and other physiological functions of plants moved to the focus of “plant science” soon after the discovery of photosynthesis, if not earlier. The research in this field recently intensified...
Tue Mar 17, 2020 02:00
Membranes, Vol. 10, Pages 46: Influence of Anion Structure on Thermal, Mechanical and CO2 Solubility Properties of UV-Cross-Linked Poly(ethylene glycol) Diacrylate Iongels Membranes doi: 10.3390/membranes10030046 Authors: Martins Fdz De Añastro Olmedo-Martínez Nabais Neves Mecerreyes, Tomé Iongel-based CO2 separation membranes were prepared by fast (< 1 min) UV-initiated polymerization of poly(ethylene glycol) diacrylate (PEGDA) in the presence of different...
Tue Mar 17, 2020 02:00
Membranes, Vol. 10, Pages 45: The Use of Succinonitrile as an Electrolyte Additive for Composite-Fiber Membranes in Lithium-Ion Batteries Membranes doi: 10.3390/membranes10030045 Authors: Jahaziel Villarreal Roberto Orrostieta Chavez Sujay A. Chopade Timothy P. Lodge Mataz Alcoutlabi In the present work, the effect of temperature and additives on the ionic conductivity of mixed organic/ionic liquid electrolytes (MOILEs) was investigated by conducting galvanostatic charge/discharge...
Tue Mar 17, 2020 02:00
Metabolites, Vol. 10, Pages 112: Discrimination of Adzuki Bean (Vigna angularis) Geographical Origin by Targeted and Non-Targeted Metabolite Profiling with Gas Chromatography Time-of-Flight Mass Spectrometry Metabolites doi: 10.3390/metabo10030112 Authors: Tae Jin Kim Jeong Gon Park Soon Kil Ahn Kil Won Kim Jaehyuk Choi Hyun Young Kim Sun-Hwa Ha Woo Duck Seo Jae Kwang Kim As international food trade increases, consumers are becoming increasingly interested in...
Tue Mar 17, 2020 02:00
Microorganisms, Vol. 8, Pages 425: Quorum-Sensing Regulation of Antimicrobial Resistance in Bacteria
Microorganisms, Vol. 8, Pages 425: Quorum-Sensing Regulation of Antimicrobial Resistance in Bacteria Microorganisms doi: 10.3390/microorganisms8030425 Authors: Zhao Yu Ding Quorum sensing is a cell-to-cell communication system that exists widely in the microbiome and is related to cell density. The high-density colony population can generate a sufficient number of small molecule signals, activate a variety of downstream cellular processes including virulence and drug resistance...
Tue Mar 17, 2020 02:00
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