Yang Sun, Sam Shiyao Yang, Lucinda Siyun Tan
Indian Journal of Dermatology, Venereology, and Leprology 2020 86(3):325-328
A 49-year-old lady, newly diagnosed with acute myeloid leukemia, was admitted for the first cycle of induction chemotherapy using daunorubicin (days 1 to 3) and cytarabine (days 1 to 7). She had no significant past medical history. On day 7, she developed marked erythema and edema over both her ears [Figure 1]. There were no auditory complaints, and otoscopic examination reviewed clear tympanic membranes with no effusions. The condition was associated with pruritic purpura over her limbs and trunk, with 5% of body surface area involvement [Figure 2]. There was no positive Nikolsky's sign or mucositis. Histology of the affected skin over the trunk demonstrated spongiosis and superficial perivascular mixed infiltrates composed of lymphocytes, histiocytes, plasma cells and neutrophils [Figure 3].
Figure 1: Click here to view |
Figure 2: Purpura on the upper limb Click here to view |
Figure 3: Click here to view |
What Condition Is This? |
View Answer
Declaration of patient consent
The authors certify that they have obtained all appropriate patient consent forms. In the form, the patient has given her consent for her images and other clinical information to be reported in the journal. The patient understands that name and initials will not be published and due efforts will be made to conceal identity, but anonymity cannot be guaranteed.
Financial support and sponsorship
Nil.
Conflicts of interest
There are no conflicts of interest.
References |
1. | |
2. | |
3. | |
4. | |
5. |
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου