Neurophysiological Features of Cognitive Activity in Patients with Anxiety-Depressive and Hypochondriasis Disorders

Neurophysiological Features of Cognitive Activity in Patients with Anxiety-Depressive and Hypochondriasis Disorders:

Objective. To study the neurophysiological features of cognitive activity in patients with anxiety-depressive and hypochondriasis disorders. Materials and methods. A total of 65 subjects were studied: 16 with hypochondriasis disorder, 23 with mixed anxiety and depressive disorder, and 26 healthy subjects. Heart rate variability and electroencephalography methods were used. Results and conclusions. The EEG showed a decrease in the β1 range after performance of a cognitive task in patients with anxiety-depressive disorder. Patients with hypochondriasis disorder showed a decrease in the duration of the R–R interval and an increase in the frequency of the resting β1 range, an increase in the dominant frequency of β2 activity during performance of the cognitive task, and an increase in the spread of θ frequencies after cognitive tests.