Antibiotics, Vol. 9, Pages 367: Antimicrobial Activity of Five Apitoxins from Apis mellifera on Two Common Foodborne Pathogens Antibiotics doi: 10.3390/antibiotics9070367 Authors: Lamas Arteaga Regal Vázquez Miranda Cepeda Franco Antimicrobial resistance is one of today’s major public health challenges. Infections caused by multidrug-resistant bacteria have been responsible for an increasing number of deaths in recent decades. These resistant bacteria...
Tue Jun 30, 2020 03:00
Antibiotics, Vol. 9, Pages 366: Analogues of A Cyclic Antimicrobial Peptide with A Flexible Linker Show Promising Activity against Pseudomonas Aeruginosa and Staphylococcus Aureus Antibiotics doi: 10.3390/antibiotics9070366 Authors: Thomsen Mendel Al-Mansour Oddo Løbner-Olesen Hansen The emergence of multi-drug resistant bacteria is becoming a major health concern. New strategies to combat especially Gram-negative pathogens are urgently needed. Antimicrobial peptides...
Tue Jun 30, 2020 03:00
Antioxidants, Vol. 9, Pages 566: Honey Extracts Exhibit Cytoprotective Properties against UVB-Induced Photodamage in Human Experimental Skin Models Antioxidants doi: 10.3390/antiox9070566 Authors: Karapetsas Voulgaridou Iliadi Tsochantaridis Michail Kynigopoulos Lambropoulou Stavropoulou Stathopoulou Karabournioti Aligiannis Gardikis Galanis Panayiotidis Pappa In the present study, we aimed to examine the antioxidant, antiaging...
Tue Jun 30, 2020 03:00
Atmosphere, Vol. 11, Pages 697: How Unusual were June 2019 Temperatures in the Context of European Climatology? Atmosphere doi: 10.3390/atmos11070697 Authors: Agnieszka Sulikowska Agnieszka Wypych The aims of the study were to assess the severity of temperature conditions in Europe, in June 2019, using a newly developed extremes index, as well as to evaluate circulation conditions that favored the occurrence of extremely hot days in June 2019, as seen over the long term. The main...
Tue Jun 30, 2020 03:00
Atmosphere, Vol. 11, Pages 696: Impact of the Emission Control of Diesel Vehicles on Black Carbon (BC) Concentrations over China Atmosphere doi: 10.3390/atmos11070696 Authors: Jiamao Zhou Xuexi Tie Yunbo Yu Shuyu Zhao Guohui Li Suixin Liu Ting Zhang Wenting Dai In order to reduce black carbon (BC) emissions from diesel vehicles, a regional atmospheric chemistry model (WRF-Chem) was used to investigate the effects of installing a high-efficiency device for vehicle...
Tue Jun 30, 2020 03:00
Atmosphere, Vol. 11, Pages 695: Assessing the Impact of Road Traffic Reorganization on Air Quality: A Street Canyon Case Study Atmosphere doi: 10.3390/atmos11070695 Authors: Bogacki Oleniacz Rzeszutek Bździuch Szulecka Gorzelnik One of the elements of strategy aimed at minimizing the impact of road transport on air quality is the introduction of its reorganization resulting in decreased pollutant emissions to the air. The aim of the study was to determine the optimal...
Tue Jun 30, 2020 03:00
Atmosphere, Vol. 11, Pages 694: Concepts and New Implements for Modified Physiologically Equivalent Temperature Atmosphere doi: 10.3390/atmos11070694 Authors: Yung-Chang Chen Wei-Nai Chen Charles C.-K. Chou Andreas Matzarakis Different kinds of thermal indices have been applied in several decades as essential tools to investigate thermal perception, environmentally thermal conditions, occupant thermal risk, public health, tourist attractiveness, and urban climate. Physiologically...
Tue Jun 30, 2020 03:00
Atmosphere, Vol. 11, Pages 692: Damaging Convective and Non-Convective Winds in Southwestern Iberia during Windstorm Xola Atmosphere doi: 10.3390/atmos11070692 Authors: Pinto Belo-Pereira On 23 December 200923/12/2009, windstorm Xola struck mainland Portugal, causing serious damage in a small area north of Lisbon (Oeste region) and in the south region, inflicting economic losses of over EUR 100 million. In both areas, several power towers, designed to withstand up to 46 ms−1...
Tue Jun 30, 2020 03:00
Atmosphere, Vol. 11, Pages 693: Dispersion of CO Using Computational Fluid Dynamics in a Real Urban Canyon in the City Center of Valencia (Spain) Atmosphere doi: 10.3390/atmos11070693 Authors: Marulanda Tobón Moncho-Esteve Martínez-Corral Palau-Salvador One of the main environmental problems we are currently facing is air pollution. Air quality models calculate how much pollution is emitted and dispersed into the atmosphere. This research presents a Computational Fluid Dynamic...
Tue Jun 30, 2020 03:00
Atmosphere, Vol. 11, Pages 691: Historical Radial Growth of Chinese Torreya Trees and Adaptation to Climate Change Atmosphere doi: 10.3390/atmos11070691 Authors: Xiongwen Chen Chinese Torreya is a vital crop tree with an average life span of a thousand years in subtropical China. Plantations of this tree are broadly under construction, to benefit the local economy. Information on the growth and adaptation to climate change for this species is limited, but tree rings might show responses...
Tue Jun 30, 2020 03:00
Atmosphere, Vol. 11, Pages 690: Monoterpene Chemical Speciation with High Time Resolution Using a FastGC/PTR-MS: Results from the COV3ER Experiment on Quercus ilex Atmosphere doi: 10.3390/atmos11070690 Authors: Bsaibes Piel Gros Truong Lafouge Ciuraru Buysse Kammer Loubet Staudt Monoterpenes (MTs) represent an important family of biogenic volatile organic compounds (BVOCs) in terms of amount and chemical diversity. This family has been extensively...
Tue Jun 30, 2020 03:00
Bioengineering, Vol. 7, Pages 65: Regulation of the Ocular Cell/Tissue Response by Implantable Biomaterials and Drug Delivery Systems Bioengineering doi: 10.3390/bioengineering7030065 Authors: Francesco Baino Saeid Kargozar Therapeutic advancements in the treatment of various ocular diseases is often linked to the development of efficient drug delivery systems (DDSs), which would allow a sustained release while maintaining therapeutic drug levels in the target tissues. In this way,...
Tue Jun 30, 2020 03:00
Biology, Vol. 9, Pages 146: Structural Insights into the Evolutionarily Conserved BAF Chromatin Remodeling Complex Biology doi: 10.3390/biology9070146 Authors: Marcum Reyes He The switch/sucrose nonfermentable (SWI/SNF) family of proteins acts to regulate chromatin accessibility and plays an essential role in multiple cellular processes. A high frequency of mutations has been found in SWI/SNF family subunits by exome sequencing in human cancer, and multiple studies support...
Tue Jun 30, 2020 03:00
Biomedicines, Vol. 8, Pages 187: Regulatory Effects of Skate Skin-Derived Collagen Peptides with Different Molecular Weights on Lipid Metabolism in the Liver and Adipose Tissue Biomedicines doi: 10.3390/biomedicines8070187 Authors: Woo Noh This study investigated the effects of skate skin collagen peptide (SSCP) with different molecular weights (MWs) on the lipid metabolism in the liver and adipose tissue. Male db/db mice were orally administered with water (control group) or low...
Tue Jun 30, 2020 03:00
Biomedicines, Vol. 8, Pages 186: The Role of Cutibacterium acnes in Intervertebral Disc Inflammation
Biomedicines, Vol. 8, Pages 186: The Role of Cutibacterium acnes in Intervertebral Disc Inflammation Biomedicines doi: 10.3390/biomedicines8070186 Authors: Schmid Hausmann Hitzl Achermann Wuertz-Kozak Recently, the role of infection of the intervertebral disc (IVD) with Cutibacterium acnes (C. acnes) as a contributor to disc-related low back pain (LBP) has been discussed. The aim of this study was to investigate whether and how C. acnes contributes to the inflammatory...
Tue Jun 30, 2020 03:00
Biomedicines, Vol. 8, Pages 185: It Takes Two: Dimerization Is Essential for the Broad-Spectrum Predatory and Defensive Activities of the Venom Peptide Mp1a from the Jack Jumper Ant Myrmecia pilosula Biomedicines doi: 10.3390/biomedicines8070185 Authors: Nixon Dekan Robinson Guo Vetter Kotze Alewood King Herzig Ant venoms have recently attracted increased attention due to their chemical complexity, novel molecular frameworks, and diverse biological activities....
Tue Jun 30, 2020 03:00
Biomolecules, Vol. 10, Pages 983: Unveiling the Mechanism of Action of 7α-acetoxy-6β-hydroxyroyleanone on an MRSA/VISA Strain: Membrane and Cell Wall Interactions Biomolecules doi: 10.3390/biom10070983 Authors: Filipe Pereira Teresa Figueiredo Rodrigo F. M. de Almeida Catarina A. C. Antunes Catarina Garcia Catarina P. Reis Lia Ascensão Rita G. Sobral Patricia Rijo The number of cases of failure in the treatment of infections associated with resistant bacteria...
Tue Jun 30, 2020 03:00
Biomolecules, Vol. 10, Pages 980: Natural Ergot Alkaloids in Ocular Pharmacotherapy: Known Molecules for Novel Nanoparticle-Based Delivery Systems Biomolecules doi: 10.3390/biom10070980 Authors: Baldim Oliveira Kadian Rao Yadav Mahant Lucarini Durazzo Da Ana Capasso Souto Santini Souto Several pharmacological properties are attributed to ergot alkaloids as a result of their antibacterial, antiproliferative, and antioxidant effects. Although...
Tue Jun 30, 2020 03:00
Biomolecules, Vol. 10, Pages 982: Tumoricidal and Bactericidal Properties of ZnONPs Synthesized Using Cassia auriculata Leaf Extract Biomolecules doi: 10.3390/biom10070982 Authors: Prasad Prasad Ansari Alzohairy Alomary AlYahya Srinivasa Murali Ankegowda Shivamallu In this work, we aimed to synthesize zinc oxide nanoparticles (ZnONPs) using an aqueous extract of Cassia auriculata leaves (CAE) at room temperature without the provision of additional...
Tue Jun 30, 2020 03:00
Biomolecules, Vol. 10, Pages 979: Mechanisms of Resistance to Immunotoxins Containing Pseudomonas Exotoxin A in Cancer Therapy Biomolecules doi: 10.3390/biom10070979 Authors: Dieffenbach Pastan Immunotoxins are a class of targeted cancer therapeutics in which a toxin such as Pseudomonas exotoxin A (PE) is linked to an antibody or cytokine to direct the toxin to a target on cancer cells. While a variety of PE-based immunotoxins have been developed and a few have demonstrated promising...
Tue Jun 30, 2020 03:00
Biomolecules, Vol. 10, Pages 978: An Economic Dilemma Between Molecular Weapon Systems May Explain an Arachno-atypical Venom in Wasp Spiders (Argiope bruennichi) Biomolecules doi: 10.3390/biom10070978 Authors: Lüddecke Reumont Förster Billion Timm Lochnit Vilcinskas Lemke Spiders use venom to subdue their prey, but little is known about the diversity of venoms in different spider families. Given the limited data available for orb-weaver spiders (Araneidae),...
Tue Jun 30, 2020 03:00
Biomolecules, Vol. 10, Pages 977: Survey and Validation of tRNA Modifications and Their Corresponding Genes in Bacillus subtilis sp Subtilis Strain 168 Biomolecules doi: 10.3390/biom10070977 Authors: de Crécy-Lagard Ross Jaroch Marchand Eisenhart Brégeon Motorin Limbach Extensive knowledge of both the nature and position of tRNA modifications in all cellular tRNAs has been limited to two bacteria, Escherichia coli and Mycoplasma capricolum. Bacillus subtilis...
Tue Jun 30, 2020 03:00
Biomolecules, Vol. 10, Pages 981: Prediction Value of Serum NGAL in the Diagnosis and Prognosis of Experimental Acute and Chronic Kidney Injuries Biomolecules doi: 10.3390/biom10070981 Authors: Wang Li Chen Wu Zhang Chen Sensitive and accurate serum biomarkers for monitoring acute and chronic kidney disease progression are more convenient and can better evaluate drug efficiency in pharmacological research. Neutrophil Gelatinase‐associated Lipocalin (NGAL) is considered...
Tue Jun 30, 2020 03:00
Brain Sciences, Vol. 10, Pages 411: Neurodevelopmental Consequences of Pediatric Cancer and Its Treatment: The Role of Sleep Brain Sciences doi: 10.3390/brainsci10070411 Authors: Maria Paola Mogavero Oliviero Bruni Lourdes M. DelRosso Raffaele Ferri Cognitive impairment is frequent in pediatric cancer, and behavioral and psychological disturbances often also affect children who have survived cancer problems. Furthermore, pediatric tumors are also often associated with sleep...
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Brain Sciences, Vol. 10, Pages 410: Evidence-Based Physical Therapy for Individuals with Rett Syndrome: A Systematic Review Brain Sciences doi: 10.3390/brainsci10070410 Authors: Fonzo Sirico Corrado Rett syndrome is a rare genetic disorder that affects brain development and causes severe mental and physical disability. This systematic review analyzes the most recent evidence concerning the role of physical therapy in the management of individuals with Rett syndrome. The review...
Tue Jun 30, 2020 03:00
Brain Sciences, Vol. 10, Pages 409: Ultrasound Stimulation Increases Neurite Regeneration in Injured Dorsal Root Ganglion Neurons through Mammalian Target of Rapamycin Activation Brain Sciences doi: 10.3390/brainsci10070409 Authors: Han Park Choi Youn Ultrasound stimulation (US) is reported to be a safe and useful technology for improving injured nerve regeneration. However, the intracellular mechanisms underlying its stimulatory effects are only partially understood. Mammalian...
Tue Jun 30, 2020 03:00
Brain Sciences, Vol. 10, Pages 408: Markers of Regenerative Processes in Patients with Bipolar Disorder: A Case-control Study Brain Sciences doi: 10.3390/brainsci10070408 Authors: Reginia Samochowiec Jabłoński Ferensztajn-Rochowiak Rybakowski Telesiński Tarnowski Misiak Ratajczak Kucharska-Mazur Progress in medical science has allowed the discovery of many factors affecting the pathogenesis of bipolar disorder, and among the most recent research directions...
Tue Jun 30, 2020 03:00
Cancers, Vol. 12, Pages 1746: Essential Thrombocythemia and Acquired von Willebrand Syndrome: The Shadowlands between Thrombosis and Bleeding Cancers doi: 10.3390/cancers12071746 Authors: Hassan Awada Maria Teresa Voso Paola Guglielmelli Carmelo Gurnari Over the past decade, new insights have emerged on the pathophysiology of essential thrombocythemia (ET), its clinical management, and associated thrombohemostatic disturbances. Here, we review the latest diagnostic and risk...
Tue Jun 30, 2020 03:00
Cancers, Vol. 12, Pages 1744: The Potential of MLN3651 in Combination with Selumetinib as a Treatment for Merlin-Deficient Meningioma Cancers doi: 10.3390/cancers12071744 Authors: Jade Lyons Lyons Rimmer Emanuela Ercolano Daniele Baiz Mahindra Makhija Allison Berger Todd Sells Steve Stroud David Hilton Claire L Adams C Oliver Hanemann Meningioma is the most common primary intracranial tumour, and surgical resection is the main therapeutic option. Merlin is...
Tue Jun 30, 2020 03:00
Cancers, Vol. 12, Pages 1745: Cancer Stem Cell-Inducing Media Activates Senescence Reprogramming in Fibroblasts Cancers doi: 10.3390/cancers12071745 Authors: Patrick M. Perrigue Magdalena Rakoczy Kamila P. Pawlicka Agnieszka Belter Małgorzata Giel-Pietraszuk Mirosława Naskręt-Barciszewska Jan Barciszewski Marek Figlerowicz Cellular senescence is a tumor-suppressive mechanism blocking cell proliferation in response to stress. However, recent evidence suggests that...
Tue Jun 30, 2020 03:00
Cancers, Vol. 12, Pages 1743: Y Chromosome Loss is a Frequent Event in Barrett’s Adenocarcinoma and Associated with Poor Outcome Cancers doi: 10.3390/cancers12071743 Authors: Heike Loeser Christina B. Wölwer Hakan Alakus Seung-Hun Chon Thomas Zander Reinhard Buettner Axel M. Hillmer Christiane J. Bruns Wolfgang Schroeder Florian Gebauer Alexander Quaas Background: The loss of the Y chromosome in various malignant diseases has been described previously. There...
Tue Jun 30, 2020 03:00
Cancers, Vol. 12, Pages 1737: CXCR4 Inhibition Enhances Efficacy of FLT3 Inhibitors in FLT3-Mutated AML Augmented by Suppressed TGF-b Signaling Cancers doi: 10.3390/cancers12071737 Authors: Bo-Reum Kim Seung-Hyun Jung A-Reum Han Gyeongsin Park Hee-Je Kim Bin Yuan Venkata Lokesh Battula Michael Andreeff Marina Konopleva Yeun-Jun Chung Byung-Sik Cho Given the proven importance of the CXCL12/CXCR4 axis in the stroma–acute myeloid leukemia (AML) interactions...
Tue Jun 30, 2020 03:00
Cancers, Vol. 12, Pages 1739: Expression Patterns of Immune Genes Reveal Heterogeneous Subtypes of High-Risk Neuroblastoma Cancers doi: 10.3390/cancers12071739 Authors: Zhenqiu Liu Christa N. Grant Lidan Sun Barbara A. Miller Vladimir S. Spiegelman Hong-Gang Wang High risk neuroblastoma (HR-NB) remains difficult to treat, and its overall survival (OS) is still below 50%. Although HR-NB is a heterogeneous disease, HR-NB patients are currently treated in a similar fashion....
Tue Jun 30, 2020 03:00
Cancers, Vol. 12, Pages 1740: Plasma Level of Circular RNA hsa_circ_0000190 Correlates with Tumor Progression and Poor Treatment Response in Advanced Lung Cancers Cancers doi: 10.3390/cancers12071740 Authors: Yung-Hung Luo Yi-Ping Yang Chian-Shiu Chien Aliaksandr A. Yarmishyn Afeez Adekunle Ishola Yueh Chien Yuh-Min Chen Tsai-Wang Huang Kang-Yun Lee Wen-Chien Huang Ping-Hsing Tsai Tzu-Wei Lin Shih-Hwa Chiou Chao-Yu Liu Cheng-Chang Chang Ming-Teh...
Tue Jun 30, 2020 03:00
Cancers, Vol. 12, Pages 1741: Monoclonal Gammopathies of Renal Significance: Renal Biopsy and Beyond
Cancers, Vol. 12, Pages 1741: Monoclonal Gammopathies of Renal Significance: Renal Biopsy and Beyond Cancers doi: 10.3390/cancers12071741 Authors: Paolo Menè Lorenzo De Alexandris Alessandra Moioli Salvatore Raffa Antonella Stoppacciaro Monoclonal Gammopathies of Renal Significance (MGRS) are a rather heterogeneous group of renal disorders caused by a circulating monoclonal (MC) immunoglobulin (Ig) component, often in the absence of multiple myeloma (MM) or another clinically...
Tue Jun 30, 2020 03:00
Cancers, Vol. 12, Pages 1738: Digital Droplet PCR is a Specific and Sensitive Tool for Detecting IDH2 Mutations in Acute Myeloid LeuKemia Patients Cancers doi: 10.3390/cancers12071738 Authors: Grassi Guerrini Ciabatti Puccetti Salehzadeh Metelli Di Vita Domenichini Caracciolo Orciuolo Pelosini Mazzantini Rossi Mazziotta Petrini Galimberti Isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) interfere with cellular metabolism contributing...
Tue Jun 30, 2020 03:00
Cancers, Vol. 12, Pages 1742: Single Nucleotide Polymorphisms in MiRNA Binding Sites of Nucleotide Excision Repair-Related Genes Predict Clinical Benefit of Oxaliplatin in FOLFOXIRI Plus Bevacizumab: Analysis of the TRIBE Trial Cancers doi: 10.3390/cancers12071742 Authors: Mitsukuni Suenaga Marta Schirripa Shu Cao Wu Zhang Dongyun Yang Chiara Cremolini Sabina Murgioni Sara Lonardi Yan Ning Satoshi Okazaki Martin D. Berger Yuji Miyamoto Afsaneh Barzi Fotios...
Tue Jun 30, 2020 03:00
Cells, Vol. 9, Pages 1588: T-Cell Gene Therapy in Cancer Immunotherapy: Why It Is No Longer Just CARs on The Road Cells doi: 10.3390/cells9071588 Authors: Michael D. Crowther Inge Marie Svane Özcan Met T-cells have a natural ability to fight cancer cells in the tumour microenvironment. Due to thymic selection and tissue-driven immunomodulation, these cancer-fighting T-cells are generally low in number and exhausted. One way to overcome these issues is to genetically alter T-cells...
Tue Jun 30, 2020 03:00
Cells, Vol. 9, Pages 1589: Oxidative Inactivation of the Proteasome Augments Alveolar Macrophage Secretion of Vesicular SOCS3 Cells doi: 10.3390/cells9071589 Authors: Mikel D. Haggadone Peter Mancuso Marc Peters-Golden Extracellular vesicles (EVs) contain a diverse array of molecular cargoes that alter cellular phenotype and function following internalization by recipient cells. In the lung, alveolar macrophages (AMs) secrete EVs containing suppressor of cytokine signaling 3 (SOCS3),...
Tue Jun 30, 2020 03:00
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