Antibiotics, Vol. 9, Pages 640: Ceftolozane/Tazobactam and Ceftazidime/Avibactam for Multidrug-Resistant Gram-Negative Infections in Immunocompetent Patients: A Single-Center Retrospective Study Antibiotics doi: 10.3390/antibiotics9100640 Authors: Rosario Cultrera Marco Libanore Agostino Barozzi Erica d’Anchera Letizia Romanini Fabio Fabbian Francesco De Motoli Brunella Quarta Armando Stefanati Niccolò Bolognesi Giovanni Gabutti Complicated infections from...
Antibiotics, Vol. 9, Pages 641: Endophytic Streptomyces laurentii Mediated Green Synthesis of Ag-NPs with Antibacterial and Anticancer Properties for Developing Functional Textile Fabric Properties Antibiotics doi: 10.3390/antibiotics9100641 Authors: Ahmed M. Eid Amr Fouda Gniewko Niedbała Saad El-Din Hassan Salem S. Salem Abdullah M. Abdo Helal F. Hetta Tharwat I. Shaheen Improvement of the medical textile industry has received more attention recently, especially...
Antibiotics, Vol. 9, Pages 637: Anti-Biofilm Inhibitory Synergistic Effects of Combinations of Essential Oils and Antibiotics Antibiotics doi: 10.3390/antibiotics9100637 Authors: Antonio Rosato Sabina Sblano Lara Salvagno Alessia Carocci Maria Lisa Clodoveo Filomena Corbo Giuseppe Fracchiolla In recent years, the increase of bacteria antibiotic- resistance has been a severe problem for public health. A useful solution could be to join some phytochemicals naturally present...
Antibiotics, Vol. 9, Pages 639: Determination of Drug Efflux Pump Efficiency in Drug-Resistant Bacteria Using MALDI-TOF MS Antibiotics doi: 10.3390/antibiotics9100639 Authors: Wen-Jung Lu Hsuan-Ju Lin Pang-Hung Hsu Hong-Ting Victor Lin Multidrug efflux pumps play an essential role in antibiotic resistance. The conventional methods, including minimum inhibitory concentration and fluorescent assays, to monitor transporter efflux activity might have some drawbacks, such as indirect...
Antibiotics, Vol. 9, Pages 638: A Cluster of Candida auris Blood Stream Infections in a Tertiary Care Hospital in Oman from 2016 to 2019 Antibiotics doi: 10.3390/antibiotics9100638 Authors: Jalila Mohsin Sanjeewani Weerakoon Sarah Ahmed Ynze Puts Zainab Al Balushi Jacques F. Meis Abdullah M.S. Al-Hatmi (1) Background: Candida auris has been reported as emerging yeast pathogen that can cause invasive bloodstream infections in healthcare settings. It is associated with...
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Antioxidants, Vol. 9, Pages 911: Dendropanax morbifera Leaf Extracts Improved Alcohol Liver Injury in Association with Changes in the Gut Microbiota of Rats Antioxidants doi: 10.3390/antiox9100911 Authors: Taekil Eom Gwangpyo Ko Kyeoung Cheol Kim Ju-Sung Kim Tatsuya Unno This study evaluated the protective effects of Dendropanax morbifera leaf (DML) extracts in the liver due to excessive ethanol consumption. Our results showed that the ethanol extract had better antioxidant...
Antioxidants, Vol. 9, Pages 912: Enzyme-Treated Zizania latifolia Ethanol Extract Protects from UVA Irradiation-Induced Wrinkle Formation via Inhibition of Lysosome Exocytosis and Reactive Oxygen Species Generation Antioxidants doi: 10.3390/antiox9100912 Authors: Mirae An Hyungkeun Kim Joo-Myung Moon Hyun-Soo Ko Paul Clayton Young-Hee Lim Ultraviolet A (UVA) is a risk factor for photoaging and wrinkle formation. Zizania latifolia is an herbaceous perennial plant. It contains...
Antioxidants, Vol. 9, Pages 913: Pharmacokinetics and Protective Effects of Tartary Buckwheat Flour Extracts against Ethanol-Induced Liver Injury in Rats Antioxidants doi: 10.3390/antiox9100913 Authors: Hye-Rin Jin Suyong Lee Soo-Jin Choi The grains of Tartary buckwheat (Fagopyrum esculentum) are traditionally consumed on a daily basis and are used in the preparation of diverse processed foods owing to the high concentration of rutin, an antioxidant compound. However, rutin is...
Antioxidants, Vol. 9, Pages 908: The Association between Serum Bilirubin Levels and Colorectal Cancer Risk: Results from the Prospective Cooperative Health Research in the Region of Augsburg (KORA) Study in Germany Antioxidants doi: 10.3390/antiox9100908 Authors: Nazlisadat Seyed Khoei Gabriele Anton Annette Peters Heinz Freisling Karl-Heinz Wagner Emerging studies have suggested that bilirubin, particularly unconjugated bilirubin (UCB), has substantial anti-inflammatory...
Antioxidants, Vol. 9, Pages 909: Mitochondrial Glutathione: Recent Insights and Role in Disease Antioxidants doi: 10.3390/antiox9100909 Authors: Montserrat Marí Estefanía de Gregorio Cristina de Dios Vicente Roca-Agujetas Blanca Cucarull Anna Tutusaus Albert Morales Anna Colell Mitochondria are the main source of reactive oxygen species (ROS), most of them deriving from the mitochondrial respiratory chain. Among the numerous enzymatic and non-enzymatic antioxidant...
Antioxidants, Vol. 9, Pages 910: Polyphenols in Urine and Cardiovascular Risk Factors: A Cross-Sectional Analysis Reveals Gender Differences in Spanish Adolescents from the SI! Program Antioxidants doi: 10.3390/antiox9100910 Authors: Emily P. Laveriano-Santos Isabella Parilli-Moser Sonia L. Ramírez-Garza Anna Tresserra-Rimbau Carolina E. Storniolo Ana María Ruiz-León Ramón Estruch Patricia Bodega Mercedes de Miguel Amaya de Cos-Gandoy Vanesa Carral Gloria Santos-Beneit...
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Arts, Vol. 9, Pages 99: Making a Case for Balkan Music Studies Arts doi: 10.3390/arts9040099 Authors: Ivana Medić In his seminal comprehensive history of music(s) in the Balkan region, Jim Samson avoided the term “Balkan music” in favor of the less-binding title Music in the Balkans (Leiden: Brill, 2013). This, however, should not hinder us from probing the term “Balkan music” and its many connotations. In this editorial article for the Special...
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Atmosphere, Vol. 11, Pages 1030: Impact of the Indo-Pacific Warm Pool on the Hadley, Walker, and Monsoon Circulations Atmosphere doi: 10.3390/atmos11101030 Authors: Hye-Ryeom Kim Kyung-Ja Ha Suyeon Moon Hyoeun Oh Sahil Sharma The Indo-Pacific warm pool (IPWP) is enclosed by a 28 °C isotherm and plays a vital role in controlling atmospheric circulations. However, the effects of changes in regional warm pool sea surface temperatures (SSTs) remain unexplored. We divided...
Atmosphere, Vol. 11, Pages 1029: Vertical Profiles of Wind-Blown Sand Flux over Fine Gravel Surfaces and Their Implications for Field Observation in Arid Regions Atmosphere doi: 10.3390/atmos11101029 Authors: Jiaqi Liu Reiji Kimura Jing Wu We used a compact boundary layer wind tunnel equipped with a turbulence generator and a piezoelectric blown-sand meter to investigate the effects of the surface coverage of fine gravel on wind-blown sand flux. The vertical profile of wind-blown...
Atmosphere, Vol. 11, Pages 1028: Contribution of Phoretic and Electrostatic Effects to the Collection Efficiency of Submicron Aerosol Particles by Raindrops Atmosphere doi: 10.3390/atmos11101028 Authors: Pascal Lemaitre Mamadou Sow Arnaud Quérel Alexis Dépée Marie Monier Thibaut Menard Andrea Flossmann This article presents an experimental study, performed in the BERGAME setup, dedicated to studying the collection of submicron aerosol particles by raindrops. The initial...
Atmosphere, Vol. 11, Pages 1027: Effect of Climate Change on Annual Precipitation in Korea Using Data Screening Techniques and Climate Change Scenarios Atmosphere doi: 10.3390/atmos11101027 Authors: Ga-Kyun Lim Byung-Sik Kim Byung-Hyun Lee Se-Jin Jeung Precipitation is essential for understanding hydrological processes and identifying the characteristics that must be considered to protect human lives and property from natural disasters. Hydrological analyses assume that precipitation...
Atmosphere, Vol. 11, Pages 1026: A Comprehensive Gridded Dataset Associated to the Climate Change Effect on the Water Resources in the Grand Est Region, France Atmosphere doi: 10.3390/atmos11101026 Authors: Mărgărit-Mircea Nistor Ionel Haidu Ştefan Dezsi Cristina Ştefan Water resources and environment quality are nowadays under high pressure because of climate change, land use practices, as well as human actions. A comprehensive gridded dataset becomes a necessary instrument...
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Behavioral Sciences, Vol. 10, Pages 146: Job Insecurity, Family Functionality and Mental Health: A Comparative Study between Male and Female Hospitality Workers Behavioral Sciences doi: 10.3390/bs10100146 Authors: Esperanza Vargas-Jiménez Remberto Castro-Castañeda Esteban Agulló Tomás Raúl Medina Centeno The aim of the present article is to compare the family functionality, mental health and job insecurity of employees of the hospitality industry in Puerto Vallarta and Bahía...
Behavioral Sciences, Vol. 10, Pages 145: Quantifying the Predictive Role of Temperament Dimensions and Attachment Styles on the Five Factor Model of Personality Behavioral Sciences doi: 10.3390/bs10100145 Authors: Efrat Barel Yonathan Mizrachi Mayyan Nachmani Background: The present study investigated the role of temperament and attachment security in predicting individual differences in the five factor personality traits among adults. As previous studies suggested the potential...
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Beverages, Vol. 6, Pages 58: Brewing Characteristics of the Maltotriose-Positive Yeast Zygotorulaspora florentina Isolated from Oak Beverages doi: 10.3390/beverages6040058 Authors: Jarkko Nikulin Ronja Eerikäinen Mathias Hutzler Brian Gibson The use of wild yeasts in fermentation is becoming a viable option for the differentiation of beers. To achieve good fermentation rates and alcohol yields, however, such yeasts must have the ability to utilize the wort sugars maltose and...
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Biology, Vol. 9, Pages 311: The Effect of P4 + eCG Estrus Induction Protocol during the Deep and the Transition Anestrous Period on the Reproductive Performance of Crossbred Dairy Goats Biology doi: 10.3390/biology9100311 Authors: Francisco G. Véliz-Deras César A. Meza-Herrera Miguel Mellado Viridiana Contreras-Villarreal Leticia R. Gaytán-Alemán Juan M. Guillén-Muñoz Seasonal reproduction restricts the offering of goat commodities across the year. Therefore, it is crucial...
Biology, Vol. 9, Pages 310: Venous Thrombo-Embolism in Hospitalized SARS-CoV-2 Patients Treated with Three Different Anticoagulation Protocols: Prospective Observational Study Biology doi: 10.3390/biology9100310 Authors: Yaroslava Longhitano Fabrizio Racca Christian Zanza Marina Muncinelli Alberto Guagliano Elisa Peretti Anna Chiara Minerba Marta Mari Riccardo Boverio Mario Salio Guido Chichino Francesco Franceschi Andrea Piccioni Ludovico Abenavoli Mauro...
Biology, Vol. 9, Pages 309: The Effect of S-15176 Difumarate Salt on Ultrastructure and Functions of Liver Mitochondria of C57BL/6 Mice with Streptozotocin/High-Fat Diet-Induced Type 2 Diabetes Biology doi: 10.3390/biology9100309 Authors: Natalia V. Belosludtseva Vlada S. Starinets Lyubov L. Pavlik Irina B. Mikheeva Mikhail V. Dubinin Konstantin N. Belosludtsev S-15176, a potent derivative of the anti-ischemic agent trimetazidine, was reported to have multiple effects...
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Biomedicines, Vol. 8, Pages 376: The Impacts of Antivirals on the Coronavirus Genome Structure and Subsequent Pathogenicity, Virus Fitness and Antiviral Design Biomedicines doi: 10.3390/biomedicines8100376 Authors: Ching-Hung Lin Cheng-Yao Yang Shan-Chia Ou Meilin Wang Chen-Yu Lo Tsung-Lin Tsai Hung-Yi Wu With the global threat of SARS-CoV-2, much effort has been focused on treatment and disease control. However, how coronaviruses react to the treatments and whether...
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Biomolecules, Vol. 10, Pages 1364: Micromolar Valproic Acid Doses Preserve Survival and Induce Molecular Alterations in Neurodevelopmental Genes in Two Strains of Zebrafish Larvae Biomolecules doi: 10.3390/biom10101364 Authors: Andrea Messina Alessandra Boiti Valeria Anna Sovrano Paola Sgadò Autism spectrum disorders (ASDs) comprise a genetically heterogeneous group of conditions characterized by a multifaceted range of impairments and multifactorial etiology. Epidemiological...
Biomolecules, Vol. 10, Pages 1363: Recovery of Bioactive Compounds from Hazelnuts and Walnuts Shells: Quantitative–Qualitative Analysis and Chromatographic Purification Biomolecules doi: 10.3390/biom10101363 Authors: René Herrera Jarl Hemming Annika Smeds Oihana Gordobil Stefan Willför Jalel Labidi Hazelnut (HS) and walnut (WS) shells, an abundant by-product of the processing industries of these edible nuts, are traditionally considered as a low-value waste. However, they...
Biomolecules, Vol. 10, Pages 1361: IL-17A as a Potential Therapeutic Target for Patients on Peritoneal Dialysis Biomolecules doi: 10.3390/biom10101361 Authors: Vanessa Marchant Antonio Tejera-Muñoz Laura Marquez-Expósito Sandra Rayego-Mateos Raul R. Rodrigues-Diez Lucia Tejedor Laura Santos-Sanchez Jesús Egido Alberto Ortiz Jose M. Valdivielso Donald J. Fraser Manuel López-Cabrera Rafael Selgas Marta Ruiz-Ortega Chronic kidney disease (CKD) is a...
Biomolecules, Vol. 10, Pages 1362: Clustering and Fibril Formation during GNNQQNY Aggregation: A Molecular Dynamics Study Biomolecules doi: 10.3390/biom10101362 Authors: Beata Szała-Mendyk Andrzej Molski The precise kinetic pathways of peptide clustering and fibril formation are not fully understood. Here we study the initial clustering kinetics and transient cluster morphologies during aggregation of the heptapeptide fragment GNNQQNY from the yeast prion protein Sup35. We use a mid-resolution...
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Biosensors, Vol. 10, Pages 134: A Self-Referenced Diffraction-Based Optical Leaky Waveguide Biosensor Using Photofunctionalised Hydrogels Biosensors doi: 10.3390/bios10100134 Authors: Anil K. Pal Nicholas J. Goddard Hazel J. Dixon Ruchi Gupta We report a novel self-referenced diffraction-based leaky waveguide (LW) comprising a thin (~2 µm) film of a photofunctionalisable hydrogel created by covalent attachment of a biotinylated photocleavable linker to chitosan. Streptavidin...
Biosensors, Vol. 10, Pages 133: Point of Care Diagnostics in Resource-Limited Settings: A Review of the Present and Future of PoC in Its Most Needed Environment Biosensors doi: 10.3390/bios10100133 Authors: Benjamin Heidt Williane F. Siqueira Kasper Eersels Hanne Diliën Bart van Grinsven Ricardo T. Fujiwara Thomas J. Cleij Point of care (PoC) diagnostics are at the focus of government initiatives, NGOs and fundamental research alike. In high-income countries, the hope...
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Brain Sciences, Vol. 10, Pages 665: BDNF and IL-8, But Not UCHL-1 and IL-11, Are Markers of Brain Injury in Children Caused by Mild Head Trauma Brain Sciences doi: 10.3390/brainsci10100665 Authors: Marzena Tylicka Ewa Matuszczak Adam Hermanowicz Wojciech Dębek Maria Karpińska Joanna Kamińska Olga Martyna Koper-Lenkiewicz The aim of the study was to check whether the plasma levels of brain-derived neurotrophic factor (BDNF), interleukin-8 (IL-8), interleukin-11 (IL-11)...
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Cancers, Vol. 12, Pages 2755: Targeting Ca2+ Signaling in the Initiation, Promotion and Progression of Hepatocellular Carcinoma Cancers doi: 10.3390/cancers12102755 Authors: Ali Rychkov Barritt Hepatocellular carcinoma (HCC) is a considerable health burden worldwide and a major contributor to cancer-related deaths. HCC is often not noticed until at an advanced stage where treatment options are limited and current systemic drugs can usually only prolong survival for a short time....
Cancers, Vol. 12, Pages 2756: PD-1 Expression by Lymph Node and Intratumoral Regulatory T Cells Is Associated with Lymph Node Metastasis in Pancreatic Cancer Cancers doi: 10.3390/cancers12102756 Authors: Adrian M. Seifert Annabel Eymer Max Heiduk Rebekka Wehner Antje Tunger Janusz von Renesse Rahel Decker Daniela E. Aust Thilo Welsch Christoph Reissfelder Jürgen Weitz Marc Schmitz Lena Seifert Pancreatic ductal adenocarcinoma (PDAC) is characterized...
Cancers, Vol. 12, Pages 2753: Beyond Traditional Morphological Characterization of Lung Neuroendocrine Neoplasms: In Silico Study of Next-Generation Sequencing Mutations Analysis across the Four World Health Organization Defined Groups Cancers doi: 10.3390/cancers12102753 Authors: Giovanni Centonze Davide Biganzoli Natalie Prinzi Sara Pusceddu Alessandro Mangogna Elena Tamborini Federica Perrone Adele Busico Vincenzo Lagano Laura Cattaneo Gabriella Sozzi Luca...
Cancers, Vol. 12, Pages 2752: Prognostic Value of the Pace of Tumor Progression as Assessed by Serial 18F-FDG PET/CT Scan and Liquid Biopsy in Refractory Colorectal Cancer: The CORIOLAN Trial Cancers doi: 10.3390/cancers12102752 Authors: Silvia Camera Tugba Akin Telli Erwin Woff Caroline Vandeputte Pashalina Kehagias Thomas Guiot Gabriela Critchi Yacine Wissam Giacomo Bregni Elena Trevisi Andrea Pretta Chiara Senti Sophia Leduc Paraskevas Gkolfakis Frédéric...
Cancers, Vol. 12, Pages 2749: HSPA2 Chaperone Contributes to the Maintenance of Epithelial Phenotype of Human Bronchial Epithelial Cells but Has Non-Essential Role in Supporting Malignant Features of Non-Small Cell Lung Carcinoma, MCF7, and HeLa Cancer Cells Cancers doi: 10.3390/cancers12102749 Authors: Damian Robert Sojka Agnieszka Gogler-Pigłowska Katarzyna Klarzyńska Marta Klimczak Alicja Zylicz Magdalena Głowala-Kosińska Zdzisław Krawczyk Dorota Scieglinska Heat...
Cancers, Vol. 12, Pages 2754: Three-Dimensional Culture System of Cancer Cells Combined with Biomaterials for Drug Screening Cancers doi: 10.3390/cancers12102754 Authors: Teruki Nii Kimiko Makino Yasuhiko Tabata Anticancer drug screening is one of the most important research and development processes to develop new drugs for cancer treatment. However, there is a problem resulting in gaps between the in vitro drug screening and preclinical or clinical study. This is mainly because...
Cancers, Vol. 12, Pages 2744: Estrogen Receptor Signaling in Cancer Cancers doi: 10.3390/cancers12102744 Authors: Simon P. Langdon Estrogen receptor signaling plays
Cancers, Vol. 12, Pages 2751: Small-Molecule Inhibitors (SMIs) as an Effective Therapeutic Strategy for Endometrial Cancer Cancers doi: 10.3390/cancers12102751 Authors: Cristina Megino-Luque Cristian Pablo Moiola Clara Molins-Escuder Carlos López-Gil Antonio Gil-Moreno Xavier Matias-Guiu Eva Colas Núria Eritja Endometrial cancer (EC) is the sixth most common cancer in women. A continued number of low-risk EC patients at diagnosis, as well as patients diagnosed with...
Cancers, Vol. 12, Pages 2741: Competing Endogenous RNA Networks in the Epithelial to Mesenchymal Transition in Diffuse-Type of Gastric Cancer Cancers doi: 10.3390/cancers12102741 Authors: Natalia Landeros Pablo M. Santoro Gonzalo Carrasco-Avino Alejandro H. Corvalan The diffuse-type of gastric cancer (DGC), molecularly associated with epithelial to mesenchymal transition (EMT), is increasing in incidence. Loss of E-cadherin expression is the hallmark of the EMT process and is...
Cancers, Vol. 12, Pages 2750: Pancreatic Ductal Adenocarcinoma (PDAC) Organoids: The Shining Light at the End of the Tunnel for Drug Response Prediction and Personalized Medicine Cancers doi: 10.3390/cancers12102750 Authors: Pierre-Olivier Frappart Thomas G. Hofmann Pancreatic ductal adenocarcinoma (PDAC) represents 90% of pancreatic malignancies. In contrast to many other tumor entities, the prognosis of PDAC has not significantly improved during the past thirty years. Patients are...
Cancers, Vol. 12, Pages 2745: Nanoparticles in 472 Human Cerebrospinal Fluid: Changes in Extracellular Vesicle Concentration and miR-21 Expression as a Biomarker for Leptomeningeal Metastasis Cancers doi: 10.3390/cancers12102745 Authors: Kyue-Yim Lee Ji Hye Im Weiwei Lin Ho-Shin Gwak Jong Heon Kim Byong Chul Yoo Tae Hoon Kim Jong Bae Park Hyeon Jin Park Ho-Jin Kim Ji-Woong Kwon Sang Hoon Shin Heon Yoo Changjin Lee Leptomeningeal metastasis (LM)...
Cancers, Vol. 12, Pages 2743: Protein Translation Inhibition is Involved in the Activity of the Pan-PIM Kinase Inhibitor PIM447 in Combination with Pomalidomide-Dexamethasone in Multiple Myeloma Cancers doi: 10.3390/cancers12102743 Authors: Teresa Paíno Lorena González-Méndez Laura San-Segundo Luis A. Corchete Susana Hernández-García Andrea Díaz-Tejedor Esperanza M. Algarín Pedro Mogollón Montserrat Martín-Sánchez Norma C. Gutiérrez María-Victoria Mateos Mercedes...
Cancers, Vol. 12, Pages 2746: Targeting Liver Cancer Stem Cells: An Alternative Therapeutic Approach for Liver Cancer Cancers doi: 10.3390/cancers12102746 Authors: Hwa-Yong Lee In-Sun Hong The first report of cancer stem cell (CSC) from Bruce et al. has demonstrated the relatively rare population of stem-like cells in acute myeloid leukemia (AML). The discovery of leukemic CSCs prompted further identification of CSCs in multiple types of solid tumor. Recently, extensive research has...
Cancers, Vol. 12, Pages 2742: PIWI-Like 1 and PIWI-Like 2 Expression in Breast Cancer Cancers doi: 10.3390/cancers12102742 Authors: Ramona Erber Julia Meyer Helge Taubert Peter A. Fasching Sven Wach Lothar Häberle Paul Gaß Rüdiger Schulz-Wendtland Laura Landgraf Sabrina Olbricht Rudolf Jung Matthias W. Beckmann Arndt Hartmann Matthias Ruebner PIWI-like 1 and PIWI-like 2 play a role in stem cell self-renewal, and enhanced expression has been reported...
Cancers, Vol. 12, Pages 2747: Prognostic Factors in Childhood Anaplastic Large Cell Lymphoma: Long Term Results of the International ALCL99 Trial Cancers doi: 10.3390/cancers12102747 Authors: Lara Mussolin Marié-Cecilé Le Deley Elisa Carraro Christine Damm-Welk Andishe Attarbaschi Denise Williams Amos Burke Keizo Horibe Atsuko Nakazawa Grazyna Wrobel Georg Mann Monika Csóka Anne Uyttebroeck Rafael Fernández-Delgado Cerdá Auke Beishuizen Karin...
Cancers, Vol. 12, Pages 2748: Prognostic Significance of Aberrant Claudin-6 Expression in Endometrial Cancer Cancers doi: 10.3390/cancers12102748 Authors: Manabu Kojima Kotaro Sugimoto Mizuko Tanaka Yuta Endo Hitomi Kato Tsuyoshi Honda Shigenori Furukawa Hiroshi Nishiyama Takafumi Watanabe Shu Soeda Keiya Fujimori Hideki Chiba Background: Among the claudin (CLDN) family, CLDN6 exhibits aberrant expression in various cancers, but its biological relevance...
Cancers, Vol. 12, Pages 2740: Modulation of Rat Cancer-Induced Bone Pain is Independent of Spinal Microglia Activity Cancers doi: 10.3390/cancers12102740 Authors: Marta Diaz-delCastillo Rie Bager Hansen Camilla Kristine Appel Lykke Nielsen Sascha Nolsøe Nielsen Konstantinos Karyniotakis Louise M. Dahl Rikke B. Andreasen Anne-Marie Heegaard The dissemination of cancer to bone can cause significant cancer-induced bone pain (CIBP), severely impairing the patient’s...
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Cells, Vol. 9, Pages 2164: Integrative Multi-Omics Analysis in Calcific Aortic Valve Disease Reveals a Link to the Formation of Amyloid-Like Deposits Cells doi: 10.3390/cells9102164 Authors: Marina A. Heuschkel Nikolaos T. Skenteris Joshua D. Hutcheson Dewy D. van der Valk Juliane Bremer Philip Goody Jesper Hjortnaes Felix Jansen Carlijn V.C. Bouten Antoon van den Bogaerdt Ljubica Matic Nikolaus Marx Claudia Goettsch Calcific aortic valve disease...
Cells, Vol. 9, Pages 2163: FMO1 Is Involved in Excess Light Stress-Induced Signal Transduction and Cell Death Signaling Cells doi: 10.3390/cells9102163 Authors: Weronika Czarnocka Yosef Fichman Maciej Bernacki Elżbieta Różańska Izabela Sańko-Sawczenko Ron Mittler Stanisław Karpiński Because of their sessile nature, plants evolved integrated defense and acclimation mechanisms to simultaneously cope with adverse biotic and abiotic conditions. Among these are systemic...
Cells, Vol. 9, Pages 2162: At the Forefront of the Mucosal Barrier: The Role of Macrophages in the Intestine Cells doi: 10.3390/cells9102162 Authors: Barbara Ruder Christoph Becker Macrophages are part of the innate immunity and are key players for the maintenance of intestinal homeostasis. They belong to the group of mononuclear phagocytes, which exert bactericidal functions and help to clear apoptotic cells. Moreover, they play essential roles for the maintenance of epithelial integrity...
Cells, Vol. 9, Pages 2165: Correction: Nemade, H.; et al. Cyclooxygenases Inhibitors Efficiently Induce Cardiomyogenesis in Human Pluripotent Stem Cells. Cells 2020, 9, 554 Cells doi: 10.3390/cells9102165 Authors: Harshal Nemade Aviseka Acharya Umesh Chaudhari Erastus Nembo Filomain Nguemo Nicole Riet Hinrich Abken Jürgen Hescheler Symeon Papadopoulos Agapios Sachinidis The authors wish to make the following corrections to this paper [...]
Cells, Vol. 9, Pages 2161: Increased Lamin B1 Levels Promote Cell Migration by Altering Perinuclear Actin Organization Cells doi: 10.3390/cells9102161 Authors: Andrea Fracchia Tal Asraf Mali Salmon-Divon Gabi Gerlitz Cell migration requires reposition and reshaping of the cell nucleus. The nuclear lamina is highly important for migration of both primary and cancer cells. B-type lamins are important for proper migration of epicardial cells and neurons and increased lamin B to...
Cells, Vol. 9, Pages 2160: Tuberculosis-Associated MicroRNAs: From Pathogenesis to Disease Biomarkers Cells doi: 10.3390/cells9102160 Authors: Alessandro Sinigaglia Elektra Peta Silvia Riccetti Seshasailam Venkateswaran Riccardo Manganelli Luisa Barzon Tuberculosis (TB) caused by Mycobacterium tuberculosis is one of the most lethal infectious diseases with estimates of approximately 1.4 million human deaths in 2018. M. tuberculosis has a well-established ability to circumvent...
Cells, Vol. 9, Pages 2158: Development and Validation of a Fully GMP-Compliant Process for Manufacturing Stromal Vascular Fraction: A Cost-Effective Alternative to Automated Methods Cells doi: 10.3390/cells9102158 Authors: Pauline François Laurent Giraudo Julie Veran Baptiste Bertrand Chloé Dumoulin Houssein Aboudou Fanny Grimaud Marie Vogtensperger Mélanie Velier Laurent Arnaud Luc Lyonnet Stéphanie Simoncini Benjamin Guillet Françoise Dignat-George...
Cells, Vol. 9, Pages 2159: Characterization of Hematopoiesis in Sickle Cell Disease by Prospective Isolation of Stem and Progenitor Cells Cells doi: 10.3390/cells9102159 Authors: Seda S. Tolu Kai Wang Zi Yan Shouping Zhang Karl Roberts Andrew S. Crouch Gracy Sebastian Mark Chaitowitz Eric D. Fornari Evan M. Schwechter Joan Uehlinger Deepa Manwani Caterina P. Minniti Eric E. Bouhassira The consequences of sickle cell disease (SCD) include ongoing...
Cells, Vol. 9, Pages 2157: Multitasking by the OC Lineage during Bone Infection: Bone Resorption, Immune Modulation, and Microbial Niche Cells doi: 10.3390/cells9102157 Authors: Philip M. Roper Christine Shao Deborah J. Veis Bone infections, also known as infectious osteomyelitis, are accompanied by significant inflammation, osteolysis, and necrosis. Osteoclasts (OCs) are the bone-resorbing cells that work in concert with osteoblasts and osteocytes to properly maintain skeletal...
Cells, Vol. 9, Pages 2155: T3 Critically Affects the Mhrt/Brg1 Axis to Regulate the Cardiac MHC Switch: Role of an Epigenetic Cross-Talk Cells doi: 10.3390/cells9102155 Authors: Francesca Forini Giuseppina Nicolini Claudia Kusmic Romina D’Aurizio Alberto Mercatanti Giorgio Iervasi Letizia Pitto The LncRNA my-heart (Mhrt) and the chromatin remodeler Brg1 inhibit each other to respectively prevent or favor the maladaptive α-myosin-heavy-chain (Myh6) to β-myosin-heavy-chain...
Cells, Vol. 9, Pages 2156: Principal Postulates of Centrosomal Biology. Version 2020 Cells doi: 10.3390/cells9102156 Authors: Rustem E. Uzbekov Tomer Avidor-Reiss The centrosome, which consists of two centrioles surrounded by pericentriolar material, is a unique structure that has retained its main features in organisms of various taxonomic groups from unicellular algae to mammals over one billion years of evolution. In addition to the most noticeable function of organizing the microtubule...
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Challenges, Vol. 11, Pages 24: Concept of a Sino-German Summer School on Multiscale Processes in Oceans and the Atmosphere Challenges doi: 10.3390/challe11020024 Authors: Gerrit Lohmann Xueen Chen Xun Gong Shuang Li A concept for an interdisciplinary summer school for “multiscale processes in oceans and the atmosphere” is presented. It aims to deepen students’ understanding of scientific issues as well as their experience in multicultural communication....
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Children, Vol. 7, Pages 149: The Utility of Gait Deviation Index (GDI) and Gait Variability Index (GVI) in Detecting Gait Changes in Spastic Hemiplegic Cerebral Palsy Children Using Ankle–Foot Orthoses (AFO) Children doi: 10.3390/children7100149 Authors: Majewska Joanna Szczepanik Magdalena Bazarnik-Mucha Katarzyna Szymczyk Daniel Lenart-Domka Ewa Background: Cerebral palsy (CP) children present complex and heterogeneous motor disorders that cause gait deviations. Clinical...
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Climate, Vol. 8, Pages 104: Modeling and Analysis of Barriers to Climate Change Adaptation in Tehran
Climate, Vol. 8, Pages 104: Modeling and Analysis of Barriers to Climate Change Adaptation in Tehran Climate doi: 10.3390/cli8100104 Authors: Behnam Ghasemzadeh Ayyoob Sharifi Since the impacts of climate change will last for many years, adaptation to this phenomenon should be prioritized in urban management plans. Although Tehran, the capital of Iran, has been subject to a variety of climate change impacts in recent years, appropriate adaptation measures to address them are yet to...
Climate, Vol. 8, Pages 103: Performance Evaluation of Satellite-Based Rainfall Products over Nigeria
Climate, Vol. 8, Pages 103: Performance Evaluation of Satellite-Based Rainfall Products over Nigeria Climate doi: 10.3390/cli8100103 Authors: Kingsley N. Ogbu Nina R. Hounguè Imoleayo E. Gbode Bernhard Tischbein Understanding the variability of rainfall is important for sustaining rain-dependent agriculture and driving the local economy of Nigeria. Paucity and inadequate rain gauge network across Nigeria has made satellite-based rainfall products (SRPs), which offer a complete...
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Cosmetics, Vol. 7, Pages 74: Monitoring of Natural Pigments in Henna and Jagua Tattoos for Fake Detection Cosmetics doi: 10.3390/cosmetics7040074 Authors: Laura Rubio Marta Lores Carmen Garcia-Jares Temporary tattoos are a popular alternative to permanent ones. Some of them use natural pigments such as lawsone in the famous henna tattoos. Recently, jagua tattoos, whose main ingredients are genipin and geniposide, have emerged as an interesting option. This study was conducted to...
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Diagnostics, Vol. 10, Pages 747: Proteomics in Deaths by Drowning: Diagnostic Efficacy of Apolipoprotein A1 and α-1Antitrypsin, Pilot Study Diagnostics doi: 10.3390/diagnostics10100747 Authors: Diana Hernández-Romero Encarnación Sánchez-Rodríguez Eduardo Osuna Agustín Sibón Miriam Martínez-Villanueva José A. Noguera-Velasco María D. Pérez-Cárceles Drowning is one of the leading causes of death worldwide. The pathophysiology of drowning is complex and, sometimes, interpretation...
Diagnostics, Vol. 10, Pages 743: Prognostic Value of Severity Score Change for Septic Shock in the Emergency Room Diagnostics doi: 10.3390/diagnostics10100743 Authors: Tae Sik Hwang Hyun Woo Park Ha Young Park Young Sook Park The vital signs or laboratory test results of sepsis patients may change before clinical deterioration. This study examined the differences in prognostic performance when systemic inflammatory response syndrome (SIRS), Sequential Organ Failure Assessment...
Diagnostics, Vol. 10, Pages 745: Clinical Validation of a Urine Test (Uromonitor-V2®) for the Surveillance of Non-Muscle-Invasive Bladder Cancer Patients Diagnostics doi: 10.3390/diagnostics10100745 Authors: Caroline A. Sieverink Rui P. M. Batista Hugo J. M. Prazeres João Vinagre Cristina Sampaio Ricardo R. Leão Valdemar Máximo J. Alfred Witjes Paula Soares The costly and burdensome nature of the current follow-up methods in non-muscle-invasive bladder cancer...
Diagnostics, Vol. 10, Pages 742: Indocyanine Green-Enhanced Colorectal Surgery—between Being Superfluous and Being a Game-Changer Diagnostics doi: 10.3390/diagnostics10100742 Authors: Catalin Alius Corneliu Tudor Cristinel Dumitru Badiu Ana Maria Dascalu Catalin Gabriel Smarandache Alexandru Dan Sabau Ciprian Tanasescu Simona Andreea Balasescu Dragos Serban Nowadays, surgical innovations incorporate new technological conquests and must be validated by evidence-based...
Diagnostics, Vol. 10, Pages 744: Analyzing Malaria Disease Using Effective Deep Learning Approach Diagnostics doi: 10.3390/diagnostics10100744 Authors: Krit Sriporn Cheng-Fa Tsai Chia-En Tsai Paohsi Wang Medical tools used to bolster decision-making by medical specialists who offer malaria treatment include image processing equipment and a computer-aided diagnostic system. Malaria images can be employed to identify and detect malaria using these methods, in order to monitor...
Diagnostics, Vol. 10, Pages 746: Development of a Clinical MALDI-ToF Mass Spectrometry Assay for SARS-CoV-2: Rational Design and Multi-Disciplinary Team Work Diagnostics doi: 10.3390/diagnostics10100746 Authors: Ray K. Iles Raminta Zmuidinaite Jason K. Iles George Carnell Alex Sampson Jonathan L. Heeney The COVID-19 pandemic caused by the SARS-CoV-2 coronavirus has stretched national testing capacities to breaking points in almost all countries of the world. The need to...
Diagnostics, Vol. 10, Pages 740: Panoramic Ultrasound Examination of Posterior Neck Extensors in Healthy Subjects: Intra-Examiner Reliability Study Diagnostics doi: 10.3390/diagnostics10100740 Authors: Juan Antonio Valera-Calero Gracia María Gallego-Sendarrubias César Fernández-de-las-Peñas Joshua A. Cleland Ricardo Ortega-Santiago José Luis Arias-Buría Previous studies analyzing morphometry of posterior cervical muscles with ultrasound (US) imaging have mainly used Brightness...
Diagnostics, Vol. 10, Pages 739: A Rapid SARS-CoV-2 RT-PCR Assay for Low Resource Settings Diagnostics doi: 10.3390/diagnostics10100739 Authors: Arunkumar Arumugam Matthew L. Faron Peter Yu Cole Markham Michelle Wu Season Wong Quantitative reverse transcription polymerase chain reaction (RT-qPCR) assay is the gold standard recommended to test for acute SARS-CoV-2 infection. However, it generally requires expensive equipment such as RNA isolation instruments and real-time...
Diagnostics, Vol. 10, Pages 741: Whole Exome Sequencing as a Diagnostic Tool for Unidentified Muscular Dystrophy in a Vietnamese Family Diagnostics doi: 10.3390/diagnostics10100741 Authors: Ngoc-Lan Nguyen Can Thi Bich Ngoc Chi Dung Vu Thi Thu Huong Nguyen Huy Hoang Nguyen Muscular dystrophies are a group of heterogeneous clinical and genetic disorders. Two siblings presented with characteristics like muscular dystrophy, abnormal white matter, and elevated serum creatine...
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Diversity, Vol. 12, Pages 367: Temporal Evolution of Diatoms in a Temporary Pond Situated in the Massif du Sancy Mountains (Massif Central, France) and Description of a New Pinnularia Species Diversity doi: 10.3390/d12100367 Authors: Aude Beauger Elisabeth Allain Olivier Voldoire Carlos E. Wetzel Luc Ector Bart Van de Vijver A floristic survey was performed on a temporary pond, “Laqui du Seignavoux”, situated in the Mont-Dore massif of the French Massif...
Diversity, Vol. 12, Pages 368: Discovery of Two New Astyanax Cavefish Localities Leads to Further Understanding of the Species Biogeography Diversity doi: 10.3390/d12100368 Authors: Luis Espinasa Claudia Patricia Ornelas-García Laurent Legendre Sylvie Rétaux Alexandra Best Ramses Gamboa-Miranda Hector Espinosa-Pérez Peter Sprouse The Astyanax species complex has two morphs: a blind, depigmented morph which inhabits caves in México and an eyed, pigmented...
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Environments, Vol. 7, Pages 73: The Way of Macroplastic through the Environment Environments doi: 10.3390/environments7100073 Authors: Simone Lechthaler Kryss Waldschläger Georg Stauch Holger Schüttrumpf With the focus on microplastic in current research, macroplastic is often not further considered. Thus, this review paper is the first to analyse the entry paths, accumulation zones, and sinks of macroplastic in the aquatic, terrestrial, and atmospheric environment by presenting...
Environments, Vol. 7, Pages 72: Adsorption/Desorption Patterns of Selenium for Acid and Alkaline Soils of Xerothermic Environments Environments doi: 10.3390/environments7100072 Authors: Ioannis Zafeiriou Dionisios Gasparatos Ioannis Massas Selenium adsorption/desorption behavior was examined for eight Greek top soils with different properties, aiming to describe the geochemistry of the elements in the selected soils in terms of bioavailability and contamination risk by leaching....
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Foods, Vol. 9, Pages 1356: Quality Retention of Fresh Tuna Stored Using Supercooling Technology Foods doi: 10.3390/foods9101356 Authors: Taiyoung Kang Timothy Shafel Dongyoung Lee Chang Joo Lee Seung Hyun Lee Soojin Jun The present study was focused on the investigation of physiochemical changes in tuna subjected to a novel supercooling preservation, which was assisted using a combination of pulsed electric fields (PEF) and oscillating magnetic fields (OMF). Fresh tuna...
Foods, Vol. 9, Pages 1357: Game Meat Consumption—Conscious Choice or Just a Game? Foods doi: 10.3390/foods9101357 Authors: Katarzyna Niewiadomska Małgorzata Kosicka-Gębska Jerzy Gębski Krystyna Gutkowska Marzena Jeżewska-Zychowicz Marianna Sułek Game meat is constantly present on the European meat market, but a limited number of consumers are interested in its consumption. Considering the unique features of wild animal meat, we should explore what pushes consumers to include...
Foods, Vol. 9, Pages 1358: Bee Bread: Physicochemical Characterization and Phenolic Content Extraction Optimization Foods doi: 10.3390/foods9101358 Authors: Florina Dranca Florin Ursachi Mircea Oroian Beebread or ambrosia is a unique product for humans and bees, which is the result of lactic fermentation on pollen in honeycombs. Bee bread is a rich source of nutrients (proteins, vitamins) and polyphenols (such as flavonoids, flavonols, phenolic acids). This study aimed to characterize...
Foods, Vol. 9, Pages 1354: Principal Component Analysis from Mass Spectrometry Data Combined to a Sensory Evaluation as a Suitable Method for Assessing Bitterness of Enzymatic Hydrolysates Produced from Micellar Casein Proteins Foods doi: 10.3390/foods9101354 Authors: Dahlia Daher Barbara Deracinois Alain Baniel Elodie Wattez Justine Dantin Renato Froidevaux Sylvie Chollet Christophe Flahaut Enzymatic hydrolysis of food proteins generally changes the techno-functional,...
Foods, Vol. 9, Pages 1355: Application of 1H Nuclear Magnetic Resonance Spectroscopy as Spirit Drinks Screener for Quality and Authenticity Control Foods doi: 10.3390/foods9101355 Authors: Jan C. Teipel Thomas Hausler Katharina Sommerfeld Andreas Scharinger Stephan G. Walch Dirk W. Lachenmeier Thomas Kuballa Due to legal regulations, the rise of globalised (online) commerce and the need for public health protection, the analysis of spirit drinks (alcoholic beverages...
Foods, Vol. 9, Pages 1353: Development and Evaluation of qPCR Detection Method and Zn-MgO/Alginate Active Packaging for Controlling Listeria monocytogenes Contamination in Cold-Smoked Salmon Foods doi: 10.3390/foods9101353 Authors: Priya Vizzini Elena Beltrame Valentina Zanet Jasmina Vidic Marisa Manzano To answer to food industry requests to monitor the presence of L. monocytogenes in cold-smoked salmon samples and to extend their shelf-life, a qPCR protocol for the detection...
Foods, Vol. 9, Pages 1352: Exploring New and Modified Rejection-Type Thresholds Using Cricket Snack Crackers Foods doi: 10.3390/foods9101352 Authors: Ryan Ardoin Ross Romero Brian Marx Witoon Prinyawiwatkul Recently, sensory threshold concepts have been expanded to include affective perceptions of foods and beverages, especially measures of product rejection; however, each threshold interpretation depends largely on the methodology employed. By substituting cricket powder for...
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Fractal Fract, Vol. 4, Pages 48: On Some Formulas for the k-Analogue of Appell Functions and Generating Relations via k-Fractional Derivative Fractal and Fractional doi: 10.3390/fractalfract4040048 Authors: Övgü Gürel Yılmaz Raba Aktaş Fatma Taşdelen Our present investigation is mainly based on the k-hypergeometric functions which are constructed by making use of the Pochhammer k-symbol Diaz et al. 2017, which are one of the vital generalizations of hypergeometric functions. We...
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Healthcare, Vol. 8, Pages 364: Does Educational Attainment Affect Residents’ Health? Healthcare doi: 10.3390/healthcare8040364 Authors: Cuihong Long Pei Liu Chengzhi Yi Based on the data of the Chinese General Social Survey 2015 (CGSS2015), this article conducts an empirical analysis on the relationship between education and health status of Chinese residents by using the structural equation model (SEM), the propensity score matching (PSM) method, and generalized ordered logit...
Healthcare, Vol. 8, Pages 362: The Influence of Increased Prepregnancy Body Mass Index and Excessive Gestational Weight Gain on Pregnancy Course and Fetal and Maternal Perinatal Outcomes Healthcare doi: 10.3390/healthcare8040362 Authors: Milan Lackovic Dejan Filimonovic Sladjana Mihajlovic Biljana Milicic Ivana Filipovic Marija Rovcanin Dejan Dimitrijevic Dejan Nikolic Background: The aim of our study was to assess the influence of prepregnancy Body Mass Index (BMI)...
Healthcare, Vol. 8, Pages 363: Measurement Development for Japanese Clients’ Experiences during Adult Day Care Service Use (The J-AdaCa Tool) Healthcare doi: 10.3390/healthcare8040363 Authors: Takashi Naruse Anthony G. Tuckett Hiroshige Matsumoto Noriko Yamamoto-Mitani Adult day care (ADC) is among the most common services in the Japanese long-term care context, but information on how such care is offered remains scarce. This study aimed to develop a measurement tool to assess...
Healthcare, Vol. 8, Pages 360: Facilitators and Barriers Surrounding the Role of Administration in Employee Job Satisfaction in Long-Term Care Facilities: A Systematic Review Healthcare doi: 10.3390/healthcare8040360 Authors: Kimberly Lee Michael Mileski Joanna Fohn Leah Frye Lisa Brooks Previous literature has shown how associate engagement has positively impacted on productivity, job satisfaction, safety, retention, consumer sentiment, and financial performance in hospitals...
Healthcare, Vol. 8, Pages 361: Factors Associated with Disparities in Appropriate Statin Therapy in an Outpatient Inner City Population Healthcare doi: 10.3390/healthcare8040361 Authors: Giselle Alexandra Suero-Abreu Aris Karatasakis Sana Rashid Maciej Tysarowski Analise Douglas Richa Patel Emaad Siddiqui Aishwarya Bhardwaj Christine M. Gerula Daniel Matassa Lipid-lowering therapies are essential for the primary and secondary prevention of atherosclerotic cardiovascular...
Healthcare, Vol. 8, Pages 359: Vulnerability Factors Associated with Lifetime Posttraumatic Stress Disorder among Veterans 40 Years after War Healthcare doi: 10.3390/healthcare8040359 Authors: Ivone Castro-Vale Milton Severo Davide Carvalho Rui Mota-Cardoso Vulnerability factors for posttraumatic stress disorder (PTSD) development are still controversial. Our aim was to study the vulnerability factors for the development of war-related PTSD over a period of 40 years after exposure....
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Heritage, Vol. 3, Pages 1046-1062: Small Multispectral UAV Sensor and Its Image Fusion Capability in Cultural Heritage Applications Heritage doi: 10.3390/heritage3040057 Authors: Dimitris Kaimaris Aristoteles Kandylas For many decades the multispectral images of the earth’s surface and its objects were taken from multispectral sensors placed on satellites. In recent years, the technological evolution produced similar sensors (much smaller in size and weight) which can be...
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IJERPH, Vol. 17, Pages 7008: Is It High Time to Increase Elite Soccer Substitutions Permanently? International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197008 Authors: Gustavo R. Mota Izabela Aparecida dos Santos Rhaí André Arriel Moacir Marocolo Rules determine how team sport matches occur. Match-induced fatigue is specific to each sport, and may be associated with injury incidence. For example, the injury rate in soccer is distinctly higher...
IJERPH, Vol. 17, Pages 7007: Lifetime and Twelve-Month Prevalence, Persistence, and Unmet Treatment Needs of Mood, Anxiety, and Substance Use Disorders in African American and U.S. versus Foreign-Born Caribbean Women International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197007 Authors: Audrey L. Jones Susan D. Cochran Jane Rafferty Robert Joseph Taylor Vickie M. Mays There is growing diversity within the Black population in the U.S., but limited...
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