Anaplastic Thyroid Carcinoma Histologically Mimicking a Plasmacytoma.

Anaplastic Thyroid Carcinoma Histologically Mimicking a Plasmacytoma.:

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Anaplastic Thyroid Carcinoma Histologically Mimicking a Plasmacytoma.

Diagnostics (Basel). 2020 Jan 08;10(1):

Authors: Mo JH, Tan D, Zhao XS, Tjoa T, Wang BY

Abstract

Anaplastic (undifferentiated) thyroid carcinoma (ATC) is a rare malignancy which may arise from transformation of a pre-existing differentiated carcinoma. We report the unique case where a lesion of thyroid origin presented with the histological features of mature plasma cells. Immunohistochemistry confirmed the lesion to be an anaplastic thyroid carcinoma arising from papillary thyroid carcinoma. A tumor mimicking a malignancy of a different cellular origin can lead clinicians to incorrect treatment approaches. Careful correlation with clinical details and knowledge of these unique presentations is important for reaching the correct diagnosis.

PMID: 31936233 [PubMed]