Πέμπτη 16 Ιανουαρίου 2020

pubmed mol med rep [jour]


A 21‑gene Support Vector Machine classifier and a 10‑gene risk score system constructed for patients with gastric cancer.
Related ArticlesA 21‑gene Support Vector Machine classifier and a 10‑gene risk score system constructed for patients with gastric cancer. Mol Med Rep. 2019 Nov 21;: Authors: Jiang H, Gu J, Du J, Qi X, Qian C, Fei B Abstract Gastric cancer (GC) ranks fifth in terms of incidence and third in terms of tumor mortality worldwide. The present study was designed to construct a Support Vector Machine (SVM) classifier and risk score system for GC. The GSE62254...
pubmed mol med rep [jour]
20h
Increased mitochondrial DNA copy number protects hair cells and HEI‑OC1 cells against drug‑induced apoptosis.
Related ArticlesIncreased mitochondrial DNA copy number protects hair cells and HEI‑OC1 cells against drug‑induced apoptosis. Mol Med Rep. 2019 Nov 20;: Authors: Mei H, Mei D, Yu H, Sun S, Chen Y, Zhang Y, Chai R, Li H Abstract Several factors trigger apoptosis in cochlear hair cells. Previous studies have shown that mitochondria play key roles in apoptosis, but the role of mitochondrial deoxyribonucleic acid (mtDNA) copy number in the pathogenesis of...
pubmed mol med rep [jour]
20h
CARD10 promotes the progression of renal cell carcinoma by regulating the NF‑κB signaling pathway.
Related ArticlesCARD10 promotes the progression of renal cell carcinoma by regulating the NF‑κB signaling pathway. Mol Med Rep. 2019 Nov 21;: Authors: Peng L, He K, Cao Z, Bi L, Yu D, Wang Q, Wang J Abstract Previous studies have demonstrated that the expression of CARD10 is closely associated with the occurrence of tumors, and its role is mainly to promote tumor progression by activating the transcription factor NF‑κB. However, the signaling pathway...
pubmed mol med rep [jour]
20h
KR‑12‑a6 promotes the osteogenic differentiation of human bone marrow mesenchymal stem cells via BMP/SMAD signaling.
Related ArticlesKR‑12‑a6 promotes the osteogenic differentiation of human bone marrow mesenchymal stem cells via BMP/SMAD signaling. Mol Med Rep. 2019 Nov 22;: Authors: Fu L, Jin P, Hu Y, Lu H, Su L Abstract Considering the increased resistance to antibiotics in the clinic and the ideal antibacterial properties of KR‑12, the effects of KR‑12‑a6, an important analogue of KR‑12, on the osteogenic differentiation of human bone marrow mesenchymal stem cells...
pubmed mol med rep [jour]
20h
Histone 3 lysine 9 acetylation of BRG1 in the medial prefrontal cortex is associated with heroin self‑administration in rats.
Related ArticlesHistone 3 lysine 9 acetylation of BRG1 in the medial prefrontal cortex is associated with heroin self‑administration in rats. Mol Med Rep. 2019 Nov 22;: Authors: Hong Q, Liu J, Lin Z, Zhuang D, Xu W, Xu Z, Lai M, Zhu H, Zhou W, Liu H Abstract Heroin addiction is a chronic relapsing brain disorder with negative social consequences. Histone acetylation serves a role in drug‑induced behavior and neuroplasticity impairment. Brahma/SWI2‑related...
pubmed mol med rep [jour]
20h
The COL6A1 rs201153092 single nucleotide polymorphism, associates with thoracic ossification of the posterior longitudinal ligament.
Related ArticlesThe COL6A1 rs201153092 single nucleotide polymorphism, associates with thoracic ossification of the posterior longitudinal ligament. Mol Med Rep. 2019 Nov 22;: Authors: Wang P, Teng Z, Liu X, Liu X, Kong C, Lu S Abstract Thoracic ossification of the posterior longitudinal ligament (T‑OPLL) is one of the most common factors that causes thoracic spinal stenosis, resulting in intractable myelopathy and radiculopathy. Our previous study reported...
pubmed mol med rep [jour]
20h
rhBMP‑7 suppresses TGF‑β1‑induced endothelial to mesenchymal transition in circulating endothelial cells by regulating Smad5.
Related ArticlesrhBMP‑7 suppresses TGF‑β1‑induced endothelial to mesenchymal transition in circulating endothelial cells by regulating Smad5. Mol Med Rep. 2019 Nov 21;: Authors: Ge W, Mi Y, Xu S, Li T, Lu Y, Jiang J Abstract Endothelial to mesenchymal transition (EndMT) has been confirmed to participate in several cardiovascular diseases. In addition, EndMT of circulating endothelial cells (CECs) contributes to the pathology of musculoskeletal injury....
pubmed mol med rep [jour]
20h
Overexpression of GSDMC is a prognostic factor for predicting a poor outcome in lung adenocarcinoma.
Related ArticlesOverexpression of GSDMC is a prognostic factor for predicting a poor outcome in lung adenocarcinoma. Mol Med Rep. 2019 Nov 20;: Authors: Wei J, Xu Z, Chen X, Wang X, Zeng S, Qian L, Yang X, Ou C, Lin W, Gong Z, Yan Y Abstract The gasdermin (GSDM) superfamily has been demonstrated to consist of several important molecules that modulate multifunctional signal processes, such as cell pyroptosis. In this research, the roles of the GSDM superfamily...
pubmed mol med rep [jour]
20h
Neuroprotective effect of CPCGI on Alzheimer's disease and its mechanism.
Related ArticlesNeuroprotective effect of CPCGI on Alzheimer's disease and its mechanism. Mol Med Rep. 2019 Nov 20;: Authors: Wang X, Zhao J Abstract Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder causing progressive memory loss and cognitive impairment. The aberrant accumulation of amyloid‑β (Aβ) and neuroinflammation are two major events in AD. Aβ‑induced neurotoxicity and oxidative stress are also involved in the pathogenesis...
pubmed mol med rep [jour]
20h
MicroRNA‑542‑3p represses OTUB1 expression to inhibit migration and invasion of esophageal cancer cells.
Related ArticlesMicroRNA‑542‑3p represses OTUB1 expression to inhibit migration and invasion of esophageal cancer cells. Mol Med Rep. 2019 Nov 20;: Authors: Sun J, Deng Y, Shi J, Yang W Abstract Dysregulation of microRNAs (miRNAs) is involved in the pathogenesis of esophageal cancer. miRNA (miR)‑542‑3p is a tumor suppressor in multiple types of cancer. However, whether and how miR‑542‑3p contributes to the progression of esophageal cancer remains unknown,...
pubmed mol med rep [jour]
20h
Mitochondrial tRNAAla 5601C>T variant may affect the clinical expression of the LHON‑related ND4 11778G>A mutation in a family.
Related ArticlesMitochondrial tRNAAla 5601C>T variant may affect the clinical expression of the LHON‑related ND4 11778G>A mutation in a family. Mol Med Rep. 2019 Nov 22;: Authors: Ding Y, Ye YF, Li MY, Xia BH, Leng JH Abstract Certain mutations in mitochondrial DNA (mtDNA) are associated with Leber's hereditary optic neuropathy (LHON). In particular, the well‑known NADH dehydrogenase 4 (ND4) m.11778G>A mutation is one of the most common LHON‑associated...
pubmed mol med rep [jour]
20h
Cortex Mori Radicis extract promotes neurite outgrowth in diabetic rats by activating PI3K/AKT signaling and inhibiting Ca2+ influx associated with the upregulation of transient receptor potential canonical channel 1.
Related ArticlesCortex Mori Radicis extract promotes neurite outgrowth in diabetic rats by activating PI3K/AKT signaling and inhibiting Ca2+ influx associated with the upregulation of transient receptor potential canonical channel 1. Mol Med Rep. 2019 Nov 21;: Authors: Lu M, Yi T, Xiong Y, Wang Q, Yin N Abstract Cortex Mori Radicis extract (CMR) has various pharmacological properties, such as anti‑inflammatory, anti‑allergic and anti‑hyperglycemic effects....
pubmed mol med rep [jour]
20h

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