Supraglottic laryngeal sarcoidosis masquerading as supraglottitis.

Supraglottic laryngeal sarcoidosis masquerading as supraglottitis.:

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Supraglottic laryngeal sarcoidosis masquerading as supraglottitis.

BMJ Case Rep. 2020 Jan 13;13(1):

Authors: Leedman SR, Hendriks T, Leahy TW, Hall D

Abstract

Sarcoidosis is a rare multisystem disorder of unknown aetiology characterised by non-caseating granulomas in involved organs; it is a diagnosis of exclusion. Laryngeal involvement affects only 0.5%-5% of those with sarcoidosis. It is an uncommon but important cause of supraglottic inflammation and oedema and should be considered in the differential diagnosis in patients with supraglottitis. This case describes a 30-year-old man who presented with stridor and shortness of breath. Flexible nasendoscopic examination revealed a grossly oedematous, pale pink, diffusely hypertrophied epiglottis. Surgical biopsy revealed non-caseating granulomatous inflammation. In the context of exclusion of hepatitis, anti-neutrophil cytoplasmic antibody (ANCA) positivity, malignancy and mycobacterial infection, the diagnosis of supraglottic laryngeal sarcoid was made. He is being treated with azathioprine immunosuppression with symptomatic improvement.

PMID: 31937627 [PubMed - in process]