IJMS, Vol. 21, Pages 596: SLMP53-1 Inhibits Tumor Cell Growth through Regulation of Glucose Metabolism and Angiogenesis in a P53-Dependent Manner International Journal of Molecular Sciences doi: 10.3390/ijms21020596 Authors: Helena Ramos Juliana Calheiros Joana Almeida Valentina Barcherini Sónia Santos Alexandra T. P. Carvalho Maria M.M. Santos Lucília Saraiva The Warburg effect is an emerging hallmark of cancer, which has the tumor suppressor p53 as its major regulator....
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IJMS, Vol. 21, Pages 595: Role of Cyclosporine in Gingival Hyperplasia: An In Vitro Study on Gingival Fibroblasts International Journal of Molecular Sciences doi: 10.3390/ijms21020595 Authors: Lauritano Palmieri Lucchese Di Stasio Moreo Carinci Background: Gingival hyperplasia could occur after the administration of cyclosporine A. Up to 90% of the patients submitted to immunosuppressant drugs have been reported to suffer from this side effect. The role of fibroblasts...
Thu Jan 16, 2020 02:00
IJMS, Vol. 21, Pages 594: Correction: Bocheńska, K. et al. Lysosome Alterations in the Human Epithelial Cell Line HaCaT and Skin Specimens: Relevance to Psoriasis. Int. J. Mol. Sci. 2019, 20, 2255 International Journal of Molecular Sciences doi: 10.3390/ijms21020594 Authors: Katarzyna Bocheńska Marta Moskot Marcelina Malinowska Joanna Jakóbkiewicz-Banecka Aneta Szczerkowska-Dobosz Dorota Purzycka-Bohdan Joanna Pleńkowska Bartosz Słomiński Magdalena Gabig-Cimińska ...
Thu Jan 16, 2020 02:00
IJMS, Vol. 21, Pages 593: SV40 Transfected Human Anterior Cruciate Ligament Derived Ligamentocytes—Suitable as a Human in Vitro Model for Ligament Reconstruction? International Journal of Molecular Sciences doi: 10.3390/ijms21020593 Authors: Schulze-Tanzil Arnold Gögele Hahn Breier Meyer Kohl Schröpfer Schwarz Cultured human primary cells have a limited lifespan undergoing dedifferentiation or senescence. Anterior cruciate ligaments (ACL) are hypocellular...
Thu Jan 16, 2020 02:00
IJMS, Vol. 21, Pages 591: Structural, Molecular, and Functional Alterations of the Blood-Brain Barrier during Epileptogenesis and Epilepsy: A Cause, Consequence, or Both? International Journal of Molecular Sciences doi: 10.3390/ijms21020591 Authors: Löscher Friedman : The blood-brain barrier (BBB) is a dynamic, highly selective barrier primarily formed by endothelial cells connected by tight junctions that separate the circulating blood from the brain extracellular fluid. The endothelial...
Thu Jan 16, 2020 02:00
IJMS, Vol. 21, Pages 590: TGF-β/Smad3 Signalling Modulates GABA Neurotransmission: Implications in Parkinson’s Disease International Journal of Molecular Sciences doi: 10.3390/ijms21020590 Authors: Mª Dolores Muñoz Nerea de la Fuente Amelia Sánchez-Capelo γ-Aminobutiryc acid (GABA) is found extensively in different brain nuclei, including parts involved in Parkinson’s disease (PD), such as the basal ganglia and hippocampus. In PD and in different models of the disorder, an increase...
Thu Jan 16, 2020 02:00
IJMS, Vol. 21, Pages 588: Approaches to Monitor Circuit Disruption after Traumatic Brain Injury: Frontiers in Preclinical Research International Journal of Molecular Sciences doi: 10.3390/ijms21020588 Authors: Krishna Beitchman Bromberg Currier Thomas Mild traumatic brain injury (TBI) often results in pathophysiological damage that can manifest as both acute and chronic neurological deficits. In an attempt to repair and reconnect disrupted circuits to compensate for loss...
Thu Jan 16, 2020 02:00
IJMS, Vol. 21, Pages 592: Inactivity and Skeletal Muscle Metabolism: A Vicious Cycle in Old Age International Journal of Molecular Sciences doi: 10.3390/ijms21020592 Authors: Elena Rezuş Alexandra Burlui Anca Cardoneanu Ciprian Rezuş Cătălin Codreanu Mirela Pârvu Gabriela Rusu Zota Bogdan Ionel Tamba Aging is an inevitable and gradually progressive process affecting all organs and systems. The musculoskeletal system makes no exception, elderly exhibit an increased...
Thu Jan 16, 2020 02:00
IJMS, Vol. 21, Pages 589: Release of Cholecystokinin from Rat Intestinal Mucosal Cells and the Enteroendocrine Cell Line STC-1 in Response to Maleic and Succinic Acid, Fermentation Products of Alcoholic Beverages International Journal of Molecular Sciences doi: 10.3390/ijms21020589 Authors: Egberts Raza Wilgus Teyssen Kiehne Herzig : Alcoholic beverages stimulate pancreatic enzyme secretions by inducing cholecystokinin (CCK) release. CCK is the major stimulatory...
Thu Jan 16, 2020 02:00
IJMS, Vol. 21, Pages 586: Cytonemes Versus Neutrophil Extracellular Traps in the Fight of Neutrophils with Microbes International Journal of Molecular Sciences doi: 10.3390/ijms21020586 Authors: Galkina Fedorova Golenkina Stadnichuk Sud’ina Neutrophils can phagocytose microorganisms and destroy them intracellularly using special bactericides located in intracellular granules. Recent evidence suggests that neutrophils can catch and kill pathogens extracellularly using...
Thu Jan 16, 2020 02:00
IJMS, Vol. 21, Pages 585: The Role of MicroRNAs in Mammalian Fertility: From Gametogenesis to Embryo Implantation International Journal of Molecular Sciences doi: 10.3390/ijms21020585 Authors: Dessie Salilew-Wondim Samuel Gebremedhn Michael Hoelker Ernst Tholen Tsige Hailay Dawit Tesfaye The genetic codes inscribed during two key developmental processes, namely gametogenesis and embryogenesis, are believed to determine subsequent development and survival of adult life....
Thu Jan 16, 2020 02:00
IJMS, Vol. 21, Pages 587: iPSC-Derived MSCs Versus Originating Jaw Periosteal Cells: Comparison of Resulting Phenotype and Stem Cell Potential International Journal of Molecular Sciences doi: 10.3390/ijms21020587 Authors: Felix Umrath Marbod Weber Siegmar Reinert Hans-Peter Wendel Meltem Avci-Adali Dorothea Alexander Induced pluripotent stem cell-derived mesenchymal stem cell-like cells (iMSCs) are considered to be a promising source of progenitor cells for approaches...
Thu Jan 16, 2020 02:00
IJMS, Vol. 21, Pages 582: Influence of Sex on Urinary Organic Acids: A Cross-Sectional Study in Children International Journal of Molecular Sciences doi: 10.3390/ijms21020582 Authors: Caterino Ruoppolo Villani Marchese Costanzo Sotgiu Dore Franconi Campesi The characterization of urinary metabolome, which provides a fingerprint for each individual, is an important step to reach personalized medicine. It is influenced by exogenous and endogenous factors;...
Thu Jan 16, 2020 02:00
IJMS, Vol. 21, Pages 584: Mechanical Model for Catch-Bond-Mediated Cell Adhesion in Shear Flow International Journal of Molecular Sciences doi: 10.3390/ijms21020584 Authors: Long Li Wei Kang Jizeng Wang Catch bond, whose lifetime increases with applied tensile force, can often mediate rolling adhesion of cells in a hydrodynamic environment. However, the mechanical mechanism governing the kinetics of rolling adhesion of cells through catch-bond under shear flow is not yet clear....
Thu Jan 16, 2020 02:00
IJMS, Vol. 21, Pages 583: Fabrication and Characterization of Polyetherimide Electrospun Scaffolds Modified with Graphene Nano-Platelets and Hydroxyapatite Nano-Particles International Journal of Molecular Sciences doi: 10.3390/ijms21020583 Authors: Vassilis Kostopoulos Athanasios Kotrotsos Kalliopi Fouriki Alexandros Kalarakis Diana Portan Solution electrospinning process (SEP) is a versatile technique for generating non-woven fibrous materials intended to a wide range of...
Thu Jan 16, 2020 02:00
IJMS, Vol. 21, Pages 581: In Vitro Fabrication of Hybrid Bone/Cartilage Complex Using Mouse Induced Pluripotent Stem Cells International Journal of Molecular Sciences doi: 10.3390/ijms21020581 Authors: Limraksasin Kondo Zhang Okawa Osathanon Pavasant Egusa Cell condensation and mechanical stimuli play roles in osteogenesis and chondrogenesis; thus, they are promising for facilitating self-organizing bone/cartilage tissue formation in vitro from induced pluripotent...
Thu Jan 16, 2020 02:00
IJMS, Vol. 21, Pages 580: Bacteria from the Midgut of Common Cockchafer (Melolontha melolontha L.) Larvae Exhibiting Antagonistic Activity Against Bacterial Symbionts of Entomopathogenic Nematodes: Isolation and Molecular Identification International Journal of Molecular Sciences doi: 10.3390/ijms21020580 Authors: Marcin Skowronek Ewa Sajnaga Małgorzata Pleszczyńska Waldemar Kazimierczak Magdalena Lis Adrian Wiater The mechanisms of action of the complex including entomopathogenic...
Thu Jan 16, 2020 02:00
IJMS, Vol. 21, Pages 579: Chemical Mechanisms of Nanoparticle Radiosensitization and Radioprotection: A Review of Structure-Function Relationships Influencing Reactive Oxygen Species International Journal of Molecular Sciences doi: 10.3390/ijms21020579 Authors: Douglas Howard Sonia Sebastian Quy Van-Chanh Le Benjamin Thierry Ivan Kempson Metal nanoparticles are of increasing interest with respect to radiosensitization. The physical mechanisms of dose enhancement from X-rays...
Thu Jan 16, 2020 02:00
IJMS, Vol. 21, Pages 578: Pexophagy: A Model for Selective Autophagy International Journal of Molecular Sciences doi: 10.3390/ijms21020578 Authors: Kyla Germain Peter K. Kim The removal of damaged or superfluous organelles from the cytosol by selective autophagy is required to maintain organelle function, quality control and overall cellular homeostasis. Precisely how substrate selectivity is achieved, and how individual substrates are degraded during selective autophagy in response...
Thu Jan 16, 2020 02:00
IJMS, Vol. 21, Pages 577: Platelet-Rich Fibrin Facilitates One-Stage Cartilage Repair by Promoting Chondrocytes Viability, Migration, and Matrix Synthesis International Journal of Molecular Sciences doi: 10.3390/ijms21020577 Authors: Chin-Chean Wong Keng-Liang Ou Yun-Ho Lin Ming-Fang Lin Tsung-Lin Yang Chih-Hwa Chen Wing P. Chan The main aim of this study is to develop a one-stage method to combine platelet-rich fibrin (PRF) and autologous cartilage autografts for porcine...
Thu Jan 16, 2020 02:00
IJMS, Vol. 21, Pages 576: The Impact of IPTG Induction on Plasmid Stability and Heterologous Protein Expression by Escherichia coli Biofilms International Journal of Molecular Sciences doi: 10.3390/ijms21020576 Authors: Luciana Gomes Gabriel Monteiro Filipe Mergulhão This work assesses the effect of chemical induction with isopropyl β-D-1-thiogalactopyranoside (IPTG) on the expression of enhanced green fluorescent protein (eGFP) by planktonic and biofilm cells of Escherichia...
Thu Jan 16, 2020 02:00
IJMS, Vol. 21, Pages 573: Stereoselective Synthesis of Carbon-Sulfur-Bridged Glycomimetics by Photoinitiated Thiol-Ene Coupling Reactions International Journal of Molecular Sciences doi: 10.3390/ijms21020573 Authors: Magdolna Csávás Dániel Eszenyi Erika Mező László Lázár Nóra Debreczeni Marietta Tóth László Somsák Anikó Borbás Oligosaccharides and glycoconjugates are abundant in all living organisms, taking part in a multitude of biological processes. The application...
Thu Jan 16, 2020 02:00
IJMS, Vol. 21, Pages 574: GRK2-Mediated Crosstalk Between β-Adrenergic and Angiotensin II Receptors Enhances Adrenocortical Aldosterone Production In Vitro and In Vivo International Journal of Molecular Sciences doi: 10.3390/ijms21020574 Authors: Celina M. Pollard Jennifer Ghandour Natalie Cora Arianna Perez Barbara M. Parker Victoria L. Desimine Shelby L. Wertz Janelle M. Pereyra Krysten E. Ferraino Jainika J. Patel Anastasios Lymperopoulos Aldosterone...
Thu Jan 16, 2020 02:00
IJMS, Vol. 21, Pages 575: Proteomics-Based Evidence for a Pro-Oncogenic Role of ESRP1 in Human Colorectal Cancer Cells International Journal of Molecular Sciences doi: 10.3390/ijms21020575 Authors: Ugo Ala Marta Manco Giorgia Mandili Emanuela Tolosano Francesco Novelli Paolo Provero Fiorella Altruda Sharmila Fagoonee The RNA-binding protein, Epithelial Splicing Regulatory Protein 1 (ESRP1) can promote or suppress tumorigenesis depending on the cell type and disease...
Thu Jan 16, 2020 02:00
IJMS, Vol. 21, Pages 572: Unravelling the Roles of Nitrogen Nutrition in Plant Disease Defences International Journal of Molecular Sciences doi: 10.3390/ijms21020572 Authors: Yuming Sun Min Wang Luis Alejandro Jose Mur Qirong Shen Shiwei Guo Nitrogen (N) is one of the most important elements that has a central impact on plant growth and yield. N is also widely involved in plant stress responses, but its roles in host-pathogen interactions are complex as each affects the other....
Thu Jan 16, 2020 02:00
IJMS, Vol. 21, Pages 570: Phytochemicals for the Prevention and Treatment of Gastric Cancer: Effects and Mechanisms International Journal of Molecular Sciences doi: 10.3390/ijms21020570 Authors: Qian-Qian Mao Xiao-Yu Xu Ao Shang Ren-You Gan Ding-Tao Wu Atanas G. Atanasov Hua-Bin Li Gastric cancer is the fifth most common cancer, and the third most prevalent cause of cancer-related deaths in the world. Voluminous evidence has demonstrated that phytochemicals play a critical...
Thu Jan 16, 2020 02:00
IJMS, Vol. 21, Pages 571: iTRAQ-Based Quantitative Proteomic Analysis of the Arabidopsis Mutant opr3-1 in Response to Exogenous MeJA International Journal of Molecular Sciences doi: 10.3390/ijms21020571 Authors: Jiayu Qi Xiaoyun Zhao Zhen Li Jasmonates (JAs) regulate the defense of biotic and abiotic stresses, growth, development, and many other important biological processes in plants. The comprehensive proteomic profiling of plants under JAs treatment provides insights into the...
Thu Jan 16, 2020 02:00
JCM, Vol. 9, Pages 241: Immune Dysregulation in HFpEF: A Target for Mesenchymal Stem/Stromal Cell Therapy Journal of Clinical Medicine doi: 10.3390/jcm9010241 Authors: Sava Pepine March Over 26 million people worldwide suffer from heart failure, a disease associated with a 1 year mortality rate of 22%. Half of these patients present heart failure with preserved ejection fraction (HFpEF), for which there is no available therapy to improve prognosis. HFpEF is strongly associated...
Thu Jan 16, 2020 02:00
JCM, Vol. 9, Pages 243: Potential Salivary mRNA Biomarkers for Early Detection of Oral Cancer Journal of Clinical Medicine doi: 10.3390/jcm9010243 Authors: Oh Kang Kang Lee Kwon Kim Lee Choi Hong We evaluated potential biomarkers in human whole saliva for the early diagnosis of oral squamous cell carcinoma (OSCC). We selected 30 candidate genes with relevance to cancer from recent reports in PubMed. Saliva samples were obtained from 34 non-tumor control...
Thu Jan 16, 2020 02:00
JCM, Vol. 9, Pages 242: In Vitro Characterization of Dental Pulp Stem Cells Cultured in Two Microsphere-Forming Culture Plates Journal of Clinical Medicine doi: 10.3390/jcm9010242 Authors: Bu Lee Lee Hwang Kim Chang Choi Kim Jang Various three-dimensional (3D) culture methods have been introduced to overcome the limitations of in vitro culture and mimic in vivo conditions. This study aimed to evaluate two microsphere-forming culture methods and a monolayer...
Thu Jan 16, 2020 02:00
JCM, Vol. 9, Pages 240: Significance of Direct Confirmation of Growth Hormone Insensitivity for the Diagnosis of Primary IGF-I Deficiency Journal of Clinical Medicine doi: 10.3390/jcm9010240 Authors: Smyczyńska Smyczyńska Hilczer Stawerska Lewiński Primary insulin-like growth factor-I (IGF-I) deficiency is a synonym of growth hormone (GH) insensitivity (GHI), however the necessity of direct confirmation of GH resistance by IGF-I generation test (IGF-GT) is discussed....
Thu Jan 16, 2020 02:00
JCM, Vol. 9, Pages 239: Associations between Brain Structural Damage and Core Muscle Loss in Patients with Parkinson’s Disease Journal of Clinical Medicine doi: 10.3390/jcm9010239 Authors: Ying-Nong Wu Meng-Hsiang Chen Pi-Ling Chiang Cheng-Hsien Lu Hsiu-Ling Chen Chiun-Chieh Yu Yueh-Sheng Chen Yung-Yee Chang Wei-Che Lin Background: Parkinson’s disease (PD) is a common neurodegenerative disease associated with progressive gray matter atrophy. In addition...
Thu Jan 16, 2020 02:00
JCM, Vol. 9, Pages 236: Diagnostic Performance of Different Thyroid Imaging Reporting and Data Systems (Kwak-TIRADS, EU-TIRADS and ACR TI-RADS) for Risk Stratification of Small Thyroid Nodules (≤10 mm) Journal of Clinical Medicine doi: 10.3390/jcm9010236 Authors: Simone Schenke Rigobert Klett Philipp Seifert Michael C. Kreissl Rainer Görges Michael Zimny Due to the widespread use of ultrasound, small thyroid nodules (TNs) ≤ 10 mm are common findings. Standardized...
Thu Jan 16, 2020 02:00
JCM, Vol. 9, Pages 237: What Are the Most Effective Behavioural Strategies in Changing Postpartum Women’s Physical Activity and Healthy Eating Behaviours? A Systematic Review and Meta-Analysis Journal of Clinical Medicine doi: 10.3390/jcm9010237 Authors: Siew Lim Briony Hill Stephanie Pirotta Sharleen O’Reilly Lisa Moran Successful implementation of postpartum lifestyle interventions first requires the identification of effective core components, such as strategies for behavioural...
Thu Jan 16, 2020 02:00
JCM, Vol. 9, Pages 235: Is Complete Re-Osseointegration of an Infected Dental Implant Possible? Histologic Results of a Dog Study: A Short Communication Journal of Clinical Medicine doi: 10.3390/jcm9010235 Authors: Markus Schlee Loubna Naili Florian Rathe Urs Brodbeck Holger Zipprich Complete reosseointegration after treatment of periimplantitis was never published yet. This short scientific communication reports about results of a randomized controlled preclinical study....
Thu Jan 16, 2020 02:00
JCM, Vol. 9, Pages 238: Endotracheal Intubation Success Rate in an Urban, Supervised, Resident-Staffed Emergency Mobile System: An 11-Year Retrospective Cohort Study Journal of Clinical Medicine doi: 10.3390/jcm9010238 Authors: Michèle Chan Christophe A. Fehlmann Mathieu Pasquier Laurent Suppan Georges L. Savoldelli Objectives: In the prehospital setting, endotracheal intubation (ETI) is sometimes required to secure a patient’s airways. Emergency ETI in the field...
Thu Jan 16, 2020 02:00
JFMK, Vol. 5, Pages 4: The Effects of Asparagus Racemosus Supplementation Plus 8 Weeks of Resistance Training on Muscular Strength and Endurance Journal of Functional Morphology and Kinesiology doi: 10.3390/jfmk5010004 Authors: John Paul V. Anders Joshua L. Keller Cory M. Smith Ethan C. Hill Terry J. Housh Richard J. Schmidt Glen O. Johnson Previous studies have demonstrated that ayurvedic ingredients exhibit ergogenic (performance enhancing) properties, however, no...
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JFMK, Vol. 5, Pages 3: Progress of the Journal of Functional Morphology and Kinesiology in 2019 Journal of Functional Morphology and Kinesiology doi: 10.3390/jfmk5010003 Authors: Musumeci The Journal of Functional Morphology and Kinesiology (JFMK, ISSN: 2411-5142), which was firstly released in March 2016 [1], developed greatly in 2019 [...]
Thu Jan 16, 2020 02:00
JoF, Vol. 6, Pages 15: Oral Candidiasis: A Disease of Opportunity Journal of Fungi doi: 10.3390/jof6010015 Authors: Taissa Vila Ahmed S. Sultan Daniel Montelongo-Jauregui Mary Ann Jabra-Rizk Oral candidiasis, commonly referred to as “thrush,” is an opportunistic fungal infection that commonly affects the oral mucosa. The main causative agent, Candida albicans, is a highly versatile commensal organism that is well adapted to its human host; however, changes...
Thu Jan 16, 2020 02:00
JPM, Vol. 10, Pages 3: Drug Use in Denmark for Drugs Having Pharmacogenomics (PGx) Based Dosing Guidelines from CPIC or DPWG for CYP2D6 and CYP2C19 Drug–Gene Pairs: Perspectives for Introducing PGx Test to Polypharmacy Patients Journal of Personalized Medicine doi: 10.3390/jpm10010003 Authors: Westergaard Søgaard Nielsen Jørgensen Vermehren Background: The cytochrome P450 drug metabolizing enzymes CYP2D6 and CYP2C19 are the major targets for pharmacogenomics (PGx) testing...
Thu Jan 16, 2020 02:00
Medical Sciences, Vol. 8, Pages 4: The Presence of Immature GV− Stage Oocytes during IVF/ICSI Is a Marker of Poor Oocyte Quality: A Pilot Study Medical Sciences doi: 10.3390/medsci8010004 Authors: Pia Astbury Goutham N. Subramanian Jessica Greaney Chris Roling Jacqui Irving Hayden A. Homer Here we investigate whether the presence of germinal vesicle-stage oocytes (GV− oocytes) reflects poor oocyte developmental competence (or quality). This was a prospective,...
Thu Jan 16, 2020 02:00
Medicina, Vol. 56, Pages 34: Fibroblast Growth Factor 23-Producing Phosphaturic Mesenchymal Tumor with Extraordinary Morphology Causing Oncogenic Osteomalacia Medicina doi: 10.3390/medicina56010034 Authors: Then Asbach Bartsch Thon Betz Reincke Schmidmaier A possible cause of hypophosphatemia is paraneoplastic secretion of fibroblast growth factor 23 (FGF-23). Tumors secreting FGF-23 are rare, mostly of mesenchymal origin, usually benign, and may be located anywhere...
Thu Jan 16, 2020 02:00
Membranes, Vol. 10, Pages 15: Triple-Layer Nanocomposite Membrane Prepared by Electrospinning Based on Modified PES with Carbon Nanotubes for Membrane Distillation Applications Membranes doi: 10.3390/membranes10010015 Authors: Elmarghany El-Shazly Rajabzadeh Salem Shouman Sabry Matsuyama Nady In this work, a novel triple-layer nanocomposite membrane prepared with polyethersulfone (PES)/carbon nanotubes (CNTs) as the primary bulk material and poly (vinylidene...
Thu Jan 16, 2020 02:00
Metabolites, Vol. 10, Pages 40: Study of the Royal Jelly Free Fatty Acids by Liquid Chromatography-High Resolution Mass Spectrometry (LC-HRMS) Metabolites doi: 10.3390/metabo10010040 Authors: Kokotou Mantzourani Babaiti Kokotos The lipidome of royal jelly (RJ) consists of medium-chained (8–12 carbon atoms) free fatty acids. We present herein a liquid chromatography-high resolution mass spectrometry (HRMS) method that permits the determination of RJ fatty acids...
Thu Jan 16, 2020 02:00
Metabolites, Vol. 10, Pages 39: Sulfonamide Inhibition Profile of the β-Carbonic Anhydrase from Malassezia restricta, An Opportunistic Pathogen Triggering Scalp Conditions Metabolites doi: 10.3390/metabo10010039 Authors: Del Prete Angeli Ghobril Hitce Clavaud Marat Supuran Capasso The critical CO2 hydration reaction to bicarbonate and protons is catalyzed by carbonic anhydrases (CAs, EC 4.2.1.1). Their physiological role is to assist the transport of the...
Thu Jan 16, 2020 02:00
Metabolites, Vol. 10, Pages 38: Comparative Analysis of β-Carotene Production by Mucor circinelloides Strains CBS 277.49 and WJ11 under Light and Dark Conditions Metabolites doi: 10.3390/metabo10010038 Authors: Tahira Naz Shaista Nosheen Shaoqi Li Yusuf Nazir Kiren Mustafa Qing Liu Victoriano Garre Yuanda Song Carotenoids are natural potent antioxidants and free radical scavengers which are able to modulate the pathogenesis of some cancers and heart diseases in human,...
Thu Jan 16, 2020 02:00
MPs, Vol. 3, Pages 9: Beyond Oncology: Question Prompt Lists in Healthcare—A Scoping Review Protocol
MPs, Vol. 3, Pages 9: Beyond Oncology: Question Prompt Lists in Healthcare—A Scoping Review Protocol Methods and Protocols doi: 10.3390/mps3010009 Authors: Matthias Lukasczik Christian Gerlich Hans Dieter Wolf Heiner Vogel Question prompt lists (QPL) are an instrument to promote patient participation in medical encounters by providing a set of questions patients can use during consultations. QPL have predominantly been examined in oncology. Less is known about their use in other...
Thu Jan 16, 2020 02:00
MPs, Vol. 3, Pages 8: Enzymatic Synthesis and Flash Chromatography Separation of 1,3-Diferuloyl-sn-Glycerol and 1-Feruloyl-sn-Glycerol Methods and Protocols doi: 10.3390/mps3010008 Authors: Compton Appell Kenar Evans Ethyl ferulate was transesterified with Enova Oil (a soy-based vegetable oil containing 80–85% diacylglycerol) using Novozym 435 at 60 °C. The resultant feruloylated vegetable oil reaction product produced a precipitate (96.4 g, 4.02 wt%) after...
Thu Jan 16, 2020 02:00
Microorganisms, Vol. 8, Pages 127: Chronic Inflammatory Diseases at Secondary Sites Ensuing Urogenital or Pulmonary Chlamydia Infections Microorganisms doi: 10.3390/microorganisms8010127 Authors: Yi Ying Cheok Chalystha Yie Qin Lee Heng Choon Cheong Chung Yeng Looi Won Fen Wong Chlamydia trachomatis and C. pneumoniae are members of the Chlamydiaceae family of obligate intracellular bacteria. The former causes diseases predominantly at the mucosal epithelial layer of the urogenital...
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Microorganisms, Vol. 8, Pages 125: Detection and Identification of Bacillus anthracis: From Conventional to Molecular Microbiology Methods Microorganisms doi: 10.3390/microorganisms8010125 Authors: Zasada Rapid and reliable identification of Bacillus anthracis is of great importance, especially in the event of suspected deliberate release of anthrax spores. However, the identification of B. anthracis is challenging due to its high similarity to closely related species. Since Amerithrax...
Thu Jan 16, 2020 02:00
Microorganisms, Vol. 8, Pages 126: Nuclear Gene Transformation in the Dinoflagellate Oxyrrhis marina
Microorganisms, Vol. 8, Pages 126: Nuclear Gene Transformation in the Dinoflagellate Oxyrrhis marina Microorganisms doi: 10.3390/microorganisms8010126 Authors: Brittany N. Sprecher Huan Zhang Senjie Lin The lack of a robust gene transformation tool that allows proper expression of foreign genes and functional testing for the vast number of nuclear genes in dinoflagellates has greatly hampered our understanding of the fundamental biology in this ecologically important and evolutionarily...
Thu Jan 16, 2020 02:00
Microorganisms, Vol. 8, Pages 122: Organic Contaminant Biodegradation by Oxidoreductase Enzymes in Wastewater Treatment Microorganisms doi: 10.3390/microorganisms8010122 Authors: Barber Liu Smith Organic contaminants (OCs), such as pharmaceuticals, personal care products, flame retardants, and plasticisers, are societally ubiquitous, environmentally hazardous, and structurally diverse chemical compounds whose recalcitrance to conventional wastewater treatment necessitates the...
Thu Jan 16, 2020 02:00
Microorganisms, Vol. 8, Pages 124: Antimicrobial Sensitivity Testing of Mycoplasma bovis Isolates Derived from Western Canadian Feedlot Cattle Microorganisms doi: 10.3390/microorganisms8010124 Authors: Jelinski Kinnear Gesy Andrés-Lasheras Zaheer Weese McAllister Mycoplasma bovis is particularly adept at evading the immune system, resulting in chronic infections of the lungs and joints of feedlot cattle. The chronicity of the lesions results in prolonged antimicrobial...
Thu Jan 16, 2020 02:00
Microorganisms, Vol. 8, Pages 123: Effects of Foliar Treatment with a Trichoderma Plant Biostimulant Consortium on Passiflora caerulea L. Yield and Quality Microorganisms doi: 10.3390/microorganisms8010123 Authors: Şesan Oancea Ştefan Mănoiu Ghiurea Răut Constantinescu-Aruxandei Toma Savin Bira Pomohaci Oancea The influence of spore concentration on the ability of a Trichoderma consortium to colonize the Passiflora caerulea phyllosphere was...
Thu Jan 16, 2020 02:00
Microorganisms, Vol. 8, Pages 121: Isolation, Genomic and Metabolomic Characterization of Streptomyces tendae VITAKN with Quorum Sensing Inhibitory Activity from Southern India Microorganisms doi: 10.3390/microorganisms8010121 Authors: Nabila Mohammed Ishaque Ilia Burgsdorf Jessie James Limlingan Malit Subhasish Saha Roberta Teta Daniela Ewe Krishnan Kannabiran Pavel Hrouzek Laura Steindler Valeria Costantino Kumar Saurav Streptomyces are among the most...
Thu Jan 16, 2020 02:00
Microorganisms, Vol. 8, Pages 120: Geographical Isolation, Buried Depth, and Physicochemical Traits Drive the Variation of Species Diversity and Prokaryotic Community in Three Typical Hypersaline Environments Microorganisms doi: 10.3390/microorganisms8010120 Authors: Shaoxing Chen Yao Xu Libby Helfant The prokaryotic community composition, species diversity and the distribution patterns at various taxonomic levels in a salt lake (Chaka salt lake), solar salterns (Taipei saltworks...
Thu Jan 16, 2020 02:00
Molecules, Vol. 25, Pages 378: Structural Study on Hypochlorous Acid-Mediated Chlorination of Betanin and Its Decarboxylated Derivatives from an Anti-Inflammatory Beta vulgaris L. Extract Molecules doi: 10.3390/molecules25020378 Authors: Kumorkiewicz-Jamro Starzak Sutor Nemzer Pietrzkowski Popenda Wybraniec Hypochlorous acid (HOCl) produced by neutrophils is a part of the natural innate immune response system in the human body, but excessive levels of HOCl can...
Thu Jan 16, 2020 02:00
Molecules, Vol. 25, Pages 381: Nitrogen Fertilizer Levels Affect the Growth and Quality Parameters of Astragalus mongolica Molecules doi: 10.3390/molecules25020381 Authors: Wang Yang Xiong Nie Li Xiao Zhou Owing to overexploitation, wild resources of Astragalus mongolica, a Chinese herbal plant that is widely distributed in the arid and semi-arid areas of Northern China, have gradually become exhausted, and therefore, commercial cultivation is increasingly important...
Thu Jan 16, 2020 02:00
Molecules, Vol. 25, Pages 380: Comparison of Volatiles in Different Jasmine Tea Grade Samples Using Electronic Nose and Automatic Thermal Desorption-Gas Chromatography-Mass Spectrometry Followed by Multivariate Statistical Analysis Molecules doi: 10.3390/molecules25020380 Authors: Wang Zhao Wu Wang Ye Chinese jasmine tea is a type of flower-scented tea, which is produced by mixing green tea with the Jasminum sambac flower repeatedly. Both the total amount and composition...
Thu Jan 16, 2020 02:00
Molecules, Vol. 25, Pages 374: Honey Volatiles as a Fingerprint for Botanical Origin—A Review on their Occurrence on Monofloral Honeys Molecules doi: 10.3390/molecules25020374 Authors: Machado Miguel Vilas-Boas Figueiredo Honeys have specific organoleptic characteristics, with nutritional and health benefits, being highly appreciated by consumers, not only in food but also in the pharmaceutical and cosmetic industries. Honey composition varies between regions according to...
Thu Jan 16, 2020 02:00
Molecules, Vol. 25, Pages 373: Free Radical Scavenging Activity of Carbonyl-Amine Adducts Formed in Soybean Oil Fortified with Phosphatidylethanolamine Molecules doi: 10.3390/molecules25020373 Authors: Goritschnig Tadus König Pignitter Non-enzymatic browning reactions between lipid aldehydes and aminophospholipids might play an important role in the oxidative stability of cold-pressed vegetable oils. We, therefore, aimed to study the Maillard-type reaction between hexanal,...
Thu Jan 16, 2020 02:00
Molecules, Vol. 25, Pages 375: Performance of Graphite-Dispersed Li2CO3-K2CO3 Molten Salt Nanofluid for a Direct Absorption Solar Collector System Molecules doi: 10.3390/molecules25020375 Authors: M. A. Karim Majedul Islam Owen Arthur Prasad KDV Yarlagadda Considered to be the next generation of heat transfer fluids (HTFs), nanofluids have been receiving a growing interest over the past decade. Molten salt nanofluids have been shown to have great potential as an HTF for use...
Thu Jan 16, 2020 02:00
Molecules, Vol. 25, Pages 377: The Business of DNA Nanotechnology: Commercialization of Origami and Other Technologies Molecules doi: 10.3390/molecules25020377 Authors: Katherine E. Dunn It is often argued that DNA nanotechnology has a multitude of possible applications. However, despite great advances in the understanding of the fundamental principles of the field, to date, there has been comparatively little commercial activity. Analysis of patent applications and company case studies...
Thu Jan 16, 2020 02:00
Molecules, Vol. 25, Pages 372: Identification and Distribution of Novel Metabolites of Lolitrem B in Mice by High-Resolution Mass Spectrometry Molecules doi: 10.3390/molecules25020372 Authors: Priyanka Reddy Aaron Elkins Joanne Hemsworth Kathryn Guthridge Simone Vassiliadis Elizabeth Read German Spangenberg Simone Rochfort Lolitrem B is the most potent indole-diterpene mycotoxin produced by Epichloë festucae var. lolii (termed LpTG-1), with severe intoxication...
Thu Jan 16, 2020 02:00
Molecules, Vol. 25, Pages 376: Natural Compounds and Their Structural Analogs in Regio- and Stereoselective Synthesis of New Families of Water-Soluble 2H,3H-[1,3]thia- and -Selenazolo[3,2-a]pyridin-4-ium Heterocycles by Annulation Reactions Molecules doi: 10.3390/molecules25020376 Authors: Vladimir A. Potapov Roman S. Ishigeev Irina V. Shkurchenko Sergey V. Zinchenko Svetlana V. Amosova It has been found that both eugenol and isoeugenol derivatives reacted with 2-pyridinesulfenyl...
Thu Jan 16, 2020 02:00
Molecules, Vol. 25, Pages 370: Synthesis, Crystal Structure, and Biological Activity of a Multidentate Calix[4]arene Ligand Doubly Functionalized by 2-Hydroxybenzeledene-Thiosemicarbazone Molecules doi: 10.3390/molecules25020370 Authors: Ehsan Bahojb Noruzi Behrouz Shaabani Silvano Geremia Neal Hickey Patrizia Nitti Hossein Samadi Kafil The design and synthesis of a novel tert-butyl-calix[4]arene functionalized at 1, 3 positions of the lower rim with two terminal 2-hydroxybenzeledene-thiosemicarbazone...
Thu Jan 16, 2020 02:00
Molecules, Vol. 25, Pages 369: Production and Use of Recombinant Profilins Amb a 8, Art v 4, Bet v 2, and Phl p 12 for Allergenic Sensitization Studies Molecules doi: 10.3390/molecules25020369 Authors: Beata Cudowska A. Brenda Kapingidza Magdalena Pawłowicz Agnieszka Pampuch Noah Hyduke Swanandi Pote Caleb R. Schlachter Dariusz M. Lebensztejn Maksymilian Chruszcz Krzysztof Kowal Four recombinant (r) allergens (rAmb a 8.0101, rArt v 4.0101, rBet v 2.0101, and...
Thu Jan 16, 2020 02:00
Molecules, Vol. 25, Pages 368: Acrylamide Decreases Cell Viability, and Provides Oxidative Stress, DNA Damage, and Apoptosis in Human Colon Adenocarcinoma Cell Line Caco-2 Molecules doi: 10.3390/molecules25020368 Authors: Adriana Nowak Małgorzata Zakłos-Szyda Dorota Żyżelewicz Agnieszka Koszucka Ilona Motyl Acrylamide (AA) toxicity remains an interesting subject in toxicological research. The aim of the research performed in this paper was to determine mechanisms of cyto-...
Thu Jan 16, 2020 02:00
Molecules, Vol. 25, Pages 371: Anthocyanin Metabolites in Human Urine after the Intake of New Functional Beverages Molecules doi: 10.3390/molecules25020371 Authors: Vicente Agulló Débora Villaño Cristina García-Viguera Raúl Domínguez-Perles Sugar intake abuse is directly related with the increase of metabolic diseases such as type 2 diabetes, obesity, and insulin resistance. Along this line, the development of new beverages using alternative sweeteners could help with combatting...
Thu Jan 16, 2020 02:00
Molecules, Vol. 25, Pages 365: Experimental and Theoretical Approaches of New Nematogenic Chair Architectures of Supramolecular H-Bonded Liquid Crystals Molecules doi: 10.3390/molecules25020365 Authors: O. A. Alhaddad H. A. Ahmed M. Hagar New four isomeric chair architectures of 1:1 H-bonded supramolecular complexes were prepared through intermolecular interactions between 4-(2-(pyridin-4-yl)diazenyl-(2-(or 3-)chlorophenyl) 4-alkoxybenzoates and 4-n-alkoxybenzoic acids. The H-bond...
Thu Jan 16, 2020 02:00
Molecules, Vol. 25, Pages 366: New Paradigms to Assess Consequences of Long-Term, Low-Dose Curcumin Exposure in Lung Cancer Cells Molecules doi: 10.3390/molecules25020366 Authors: Gintare Smagurauskaite Jagdish Mahale Karen Brown Anne L. Thomas Lynne M. Howells Curcumin has been investigated extensively for cancer prevention, but it has been proposed that long-term treatments may promote clonal evolution and gain of cellular resistance, potentially rendering cancer cells...
Thu Jan 16, 2020 02:00
Molecules, Vol. 25, Pages 367: Immunomodulatory Drugs Alter the Metabolism and the Extracellular Release of Soluble Mediators by Normal Monocytes Molecules doi: 10.3390/molecules25020367 Authors: Ida Marie Rundgren Anita Ryningen Tor Henrik Anderson Tvedt Øystein Bruserud Elisabeth Ersvær Immunomodulatory drugs (IMiDs) are used in the treatment of hematological malignancies, especially multiple myeloma. IMiDs have direct anticancer effects but also indirect effects via cancer-supporting...
Thu Jan 16, 2020 02:00
Molecules, Vol. 25, Pages 364: A Recyclable, Metal-Free Mechanochemical Approach for the Oxidation of Alcohols to Carboxylic Acids Molecules doi: 10.3390/molecules25020364 Authors: Kendra Leahy Denlinger Preston Carr Daniel C. Waddell James Mack The oxidation of primary alcohols under mechanochemical conditions in a Spex8000M Mixer/Mill was investigated. To facilitate ease of separation and recyclability, a polystyrene-bound version of a TEMPO catalyst was employed. When paired...
Thu Jan 16, 2020 02:00
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