Πέμπτη 7 Μαΐου 2020


Intermolecular vibrational energy transfer enabled by microcavity strong light-matter coupling
Selective vibrational energy transfer between molecules in the liquid phase, a difficult process hampered by weak intermolecular forces, is achieved through polaritons formed by strong coupling between cavity photon modes and donor and acceptor molecules. Using pump-probe and two-dimensional infrared spectroscopy, we found that the excitation of the upper polariton, which is composed mostly of donors, can efficiently relax to the acceptors within ~5 picoseconds. The energy-transfer efficiency can...
Science: Current Issue
Thu May 07, 2020 20:40
Beat COVID-19 through innovation
Science: Current Issue
Thu May 07, 2020 20:40
Beat the heat! Stop the smoking!
Science: Current Issue
Thu May 07, 2020 20:40
News at a glance
Science: Current Issue
Thu May 07, 2020 20:40
Instantaneous contact tracing
Science: Current Issue
Thu May 07, 2020 20:40
NIH move to ax bat coronavirus grant draws fire
Science: Current Issue
Thu May 07, 2020 20:40
Imaging the onset of the resonance regime in low-energy NO-He collisions
At low energies, the quantum wave–like nature of molecular interactions results in distinctive scattering behavior, ranging from the universal Wigner laws near 0 kelvin to the occurrence of scattering resonances at higher energies. It has proven challenging to experimentally probe the individual waves underlying these phenomena. We report measurements of state-to-state integral and differential cross sections for inelastic NO-He collisions in the 0.2 to 8.5 centimeter–1 range with 0.02 centimeter–1...
Science: Current Issue
Thu May 07, 2020 20:40
Children's role in pandemic is still a puzzle
Science: Current Issue
Thu May 07, 2020 20:40
Combination prevention for COVID-19
Science: Current Issue
Thu May 07, 2020 20:40
The race is on for antibodies that stop the new coronavirus
Science: Current Issue
Thu May 07, 2020 20:40
Sensing surfaces like a mosquito
Science: Current Issue
Thu May 07, 2020 20:40
Ape researchers mobilize to save primates from coronavirus
Science: Current Issue
Thu May 07, 2020 20:40
Missing gas cooling in distant galaxies
Science: Current Issue
Thu May 07, 2020 20:40
Without fossil fuels, reactors churn out chemicals
Science: Current Issue
Thu May 07, 2020 20:40
Emergence of complexity in hierarchically organized chiral particles
The structural complexity of composite biomaterials and biomineralized particles arises from the hierarchical ordering of inorganic building blocks over multiple scales. Although empirical observations of complex nanoassemblies are abundant, the physicochemical mechanisms leading to their geometrical complexity are still puzzling, especially for nonuniformly sized components. We report the self-assembly of hierarchically organized particles (HOPs) from polydisperse gold thiolate nanoplatelets with...
Science: Current Issue
Thu May 07, 2020 20:40
Paperwork mistakes ensnare health data expert
Science: Current Issue
Thu May 07, 2020 20:40
Response to Comment on "A noninteracting low-mass black hole-giant star binary system"
Van den Heuvel and Tauris argue that if the red giant star in the system 2MASS J05215658+4359220 has a mass of 1 solar mass (M), then its unseen companion could be a binary composed of two 0.9 M stars, making a triple system. We contend that the existing data are most consistent with a giant of mass M, implying a black hole companion of M.
Science: Current Issue
Thu May 07, 2020 20:40
Meet the psychobiome
Science: Current Issue
Thu May 07, 2020 20:40
Challenges in tree-planting programs
Science: Current Issue
Thu May 07, 2020 20:40
In pursuit of open science, open access is not enough
Science: Current Issue
Thu May 07, 2020 20:40
Ultracold molecular collision dynamics
Science: Current Issue
Thu May 07, 2020 20:40
Harnessing multiple models for outbreak management
Science: Current Issue
Thu May 07, 2020 20:40
Chaperones put the brakes on opioids
Science: Current Issue
Thu May 07, 2020 20:40
Tree planting is not a simple solution
Science: Current Issue
Thu May 07, 2020 20:40
Floral recovery from accidents
Science: Current Issue
Thu May 07, 2020 20:40
Quantum resonances near absolute zero
Science: Current Issue
Thu May 07, 2020 20:40
Food shares for all
Science: Current Issue
Thu May 07, 2020 20:40
Closing the science gap in 3D metal printing
Science: Current Issue
Thu May 07, 2020 20:40
Aerodynamic imaging by mosquitoes inspires a surface detector for autonomous flying vehicles
Some flying animals use active sensing to perceive and avoid obstacles. Nocturnal mosquitoes exhibit a behavioral response to divert away from surfaces when vision is unavailable, indicating a short-range, mechanosensory collision-avoidance mechanism. We suggest that this behavior is mediated by perceiving modulations of their self-induced airflow patterns as they enter a ground or wall effect. We used computational fluid dynamics simulations of low-altitude and near-wall flights based on in vivo...
Science: Current Issue
Thu May 07, 2020 20:40
Sending copper where it is needed most
Science: Current Issue
Thu May 07, 2020 20:40
Sample collection from asteroid (162173) Ryugu by Hayabusa2: Implications for surface evolution
The near-Earth asteroid (162173) Ryugu is thought to be a primitive carbonaceous object that contains hydrated minerals and organic molecules. We report sample collection from Ryugu’s surface by the Hayabusa2 spacecraft on 21 February 2019. Touchdown images and global observations of surface colors are used to investigate the stratigraphy of the surface around the sample location and across Ryugu. Latitudinal color variations suggest the reddening of exposed surface material by solar heating and/or...
Science: Current Issue
Thu May 07, 2020 20:40
Drones become even more insect-like
Science: Current Issue
Thu May 07, 2020 20:40
A Ph.D. on hold--indefinitely
Science: Current Issue
Thu May 07, 2020 20:40
Toward artificial photosynthesis
Science: Current Issue
Thu May 07, 2020 20:40
Erratum for the Report: "Anti-Markovnikov alcohols via epoxide hydrogenation through cooperative catalysis" by C. Yao, T. Dahmen, A. Gansäuer, J. Norton
Science: Current Issue
Thu May 07, 2020 20:40
The challenge of early detection in cancer
Science: Current Issue
Thu May 07, 2020 20:40
The most effective interventions
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Thu May 07, 2020 20:40
Katherine Johnson (1918-2020)
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Thu May 07, 2020 20:40
Tracking growth dynamics
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Thu May 07, 2020 20:40

A field guide to existential risk
Science: Current Issue
Thu May 07, 2020 20:40
Elesclomol rescues Menkes disease mice
Science: Current Issue
Thu May 07, 2020 20:40
The secret lives of birds
Science: Current Issue
Thu May 07, 2020 20:40
Circumventing spatter
Science: Current Issue
Thu May 07, 2020 20:40
Research opportunities in pandemic lockdown
Science: Current Issue
Thu May 07, 2020 20:40
Hybrid approach catches light
Science: Current Issue
Thu May 07, 2020 20:40
The inherent challenges of classifying senescence
Science: Current Issue
Thu May 07, 2020 20:40
A model to study HSV-Alzheimer's link
Science: Current Issue
Thu May 07, 2020 20:40
The inherent challenges of classifying senescence--Response
Science: Current Issue
Thu May 07, 2020 20:40
Odd stem cells obstruct breath
Science: Current Issue
Thu May 07, 2020 20:40
The immune system's first steps
Science: Current Issue
Thu May 07, 2020 20:40
Stress relief
Science: Current Issue
Thu May 07, 2020 20:40
Prenatal development of human immunity
The blood and immune systems develop in parallel during early prenatal life. Waves of hematopoiesis separated in anatomical space and time give rise to circulating and tissue-resident immune cells. Previous observations have relied on animal models, which differ from humans in both their developmental timeline and exposure to microorganisms. Decoding the composition of the human immune system is now tractable using single-cell multi-omics approaches. Large-scale single-cell genomics, imaging technologies,...
Science: Current Issue
Thu May 07, 2020 20:40
Does diversity breed innovation?
Science: Current Issue
Thu May 07, 2020 20:40
Microbial-host molecular exchange and its functional consequences in early mammalian life
Molecules from symbiotic microorganisms pervasively infiltrate almost every organ system of a mammalian host, marking the initiation of microbial–host mutualism in utero, long before the newborn acquires its own microbiota. Starting from in utero development, when maternal microbial molecules can penetrate the placental barrier, we follow the different phases of adaptation through the life events of birth, lactation, and weaning, as the young mammal adapts to the microbes that colonize its body surfaces....
Science: Current Issue
Thu May 07, 2020 20:40
Elesclomol alleviates Menkes pathology and mortality by escorting Cu to cuproenzymes in mice
Loss-of-function mutations in the copper (Cu) transporter ATP7A cause Menkes disease. Menkes is an infantile, fatal, hereditary copper-deficiency disorder that is characterized by progressive neurological injury culminating in death, typically by 3 years of age. Severe copper deficiency leads to multiple pathologies, including impaired energy generation caused by cytochrome c oxidase dysfunction in the mitochondria. Here we report that the small molecule elesclomol escorted copper to the mitochondria...
Science: Current Issue
Thu May 07, 2020 20:40
Contributions of maternal and fetal antiviral immunity in congenital disease
Viral infections during pregnancy can have devastating consequences on pregnancy outcomes, fetal development, and maternal health. In this review, we examine fetal and maternal immune defense mechanisms that mediate resistance against viral infections and discuss the range of syndromes that ensue when such mechanisms fail, from fetal developmental defects to establishment of chronic infection. Further, we highlight the role of maternal immune activation, or uncontrolled inflammation triggered by...
Science: Current Issue
Thu May 07, 2020 20:40
A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV
The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2) has now become a pandemic, but there is currently very little understanding of the antigenicity of the virus. We therefore determined the crystal structure of CR3022, a neutralizing antibody previously isolated from a convalescent SARS patient, in complex with the receptor binding domain (RBD) of the SARS-CoV-2 spike (S) protein at 3.1-angstrom resolution. CR3022 targets a highly...
Science: Current Issue
Thu May 07, 2020 20:40
Vaccination strategies to enhance immunity in neonates
Neonates are particularly susceptible to infection. This vulnerability occurs despite their responsiveness to most vaccines. However, current vaccines do not target the pathogens responsible for most of the severe neonatal infections, and the time it takes to induce protective pathogen-specific immunity after vaccination limits protection in the first days to weeks of life. Alternative strategies include using vaccines to broadly stimulate neonatal immunity in a pathogen-agnostic fashion or vaccinating...
Science: Current Issue
Thu May 07, 2020 20:40
An investigation of transmission control measures during the first 50 days of the COVID-19 epidemic in China
Responding to an outbreak of a novel coronavirus [agent of coronavirus disease 2019 (COVID-19)] in December 2019, China banned travel to and from Wuhan city on 23 January 2020 and implemented a national emergency response. We investigated the spread and control of COVID-19 using a data set that included case reports, human movement, and public health interventions. The Wuhan shutdown was associated with the delayed arrival of COVID-19 in other cities by 2.91 days. Cities that implemented control...
Science: Current Issue
Thu May 07, 2020 20:40

Complex chiral particles
Science: Current Issue
Thu May 07, 2020 20:40
Light-powered CO2 fixation in a chloroplast mimic with natural and synthetic parts
Nature integrates complex biosynthetic and energy-converting tasks within compartments such as chloroplasts and mitochondria. Chloroplasts convert light into chemical energy, driving carbon dioxide fixation. We used microfluidics to develop a chloroplast mimic by encapsulating and operating photosynthetic membranes in cell-sized droplets. These droplets can be energized by light to power enzymes or enzyme cascades and analyzed for their catalytic properties in multiplex and real time. We demonstrate...
Science: Current Issue
Thu May 07, 2020 20:40
Targeting the SARS-CoV-2 spike
Science: Current Issue
Thu May 07, 2020 20:40
Controlling interdependent meso-nanosecond dynamics and defect generation in metal 3D printing
State-of-the-art metal 3D printers promise to revolutionize manufacturing, yet they have not reached optimal operational reliability. The challenge is to control complex laser–powder–melt pool interdependency (dependent upon each other) dynamics. We used high-fidelity simulations, coupled with synchrotron experiments, to capture fast multitransient dynamics at the meso-nanosecond scale and discovered new spatter-induced defect formation mechanisms that depend on the scan strategy and a competition...
Science: Current Issue
Thu May 07, 2020 20:40
Sharpening focus for anti-RSV antibodies
Science: Current Issue
Thu May 07, 2020 20:40
New Products
Science: Current Issue
Thu May 07, 2020 20:40
Atypical vibrational interactions
Science: Current Issue
Thu May 07, 2020 20:40
Comment on "A noninteracting low-mass black hole-giant star binary system"
Thompson et al. (Reports, 1 November 2019, p. 637) interpreted the unseen companion of the red giant star 2MASS J05215658+4359220 as most likely a black hole. We argue that if the red giant’s mass is ~1 solar mass, its companion can be a close binary consisting of two main-sequence stars. This would explain why no x-ray emission is detected from the system.
Science: Current Issue
Thu May 07, 2020 20:40
Collecting a sample of asteroid Ryugu
Science: Current Issue
Thu May 07, 2020 20:40
Erratum for the Report: "Widely tunable compact terahertz gas lasers" by P. Chevalier, A. Amirzhan, F. Wang, M. Piccardo, S. G. Johnson, F. Capasso, H. O. Everitt
Science: Current Issue
Thu May 07, 2020 20:40
The vaccine that keeps on giving
Science: Current Issue
Thu May 07, 2020 20:40
Quantifying SARS-CoV-2 transmission suggests epidemic control with digital contact tracing
The newly emergent human virus SARS-CoV-2 (severe acute respiratory syndrome–coronavirus 2) is resulting in high fatality rates and incapacitated health systems. Preventing further transmission is a priority. We analyzed key parameters of epidemic spread to estimate the contribution of different transmission routes and determine requirements for case isolation and contact tracing needed to stop the epidemic. Although SARS-CoV-2 is spreading too fast to be contained by manual contact tracing, it could...
Science: Current Issue
Thu May 07, 2020 20:40

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