Pituitary Adenoma and Papillary Craniopharyngioma: A Rare Case of Collision Tumor and Review of the Literature
Author links open overlay panelFredBteich13LeaEl Khoury23GeorgesNohra13VivianeTrak23SandrineYazbek13MiraAkiki2
1
Neurosurgery Department, Hotel-Dieu de France Hospital, Achrafieh, Lebanon
2
Pathology Departments, Hotel-Dieu de France Hospital, Achrafieh, Lebanon
3
Faculty of Medicine, Saint Joseph University, Achrafieh, Lebanon
Received 7 January 2020, Accepted 15 March 2020, Available online 13 April 2020.

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Background
Pituitary adenomas are the most common lesion of the sellar region. Very few cases in the literature have described their association with craniopharyngiomas in the same anatomic compartment, an entity defined as collision tumors of the sella.

Case Description
A 35-year-old man presented with headaches and progressive visual disturbances. Radiographic imaging initially highlighted the presence of a pituitary craniopharyngioma. An endoscopic transsphenoidal pituitary approach was performed, during which the tumor was partially resected. The pathology report was positive for 2 entities: a nonfunctioning pituitary adenoma and a papillary craniopharyngioma. This was an unexpected diagnosis based on the surgical and initial radiologic findings.

Conclusions
To our knowledge, this is the first documented case of a collision tumor of the sella comprising a pituitary adenoma and a craniopharyngioma of the papillary type.

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