Throughout the COVID-19 crisis, much attention has been devoted to the fraught question of how to allocate intensive care unit beds and mechanical ventilators if the supply of these resources is insufficient to provide them to all patients considered to be in need. The authors believe that the deployment of aggressive medical technology to win the “war” against the pandemic may represent the triumph of deeply human instincts over optimal policy.
Thu May 07, 2020 03:00
Although pneumonia caused by severe acute respiratory syndrome coronavirus 2 is a prominent feature of COVID-19, clinicians must consider whether treatment for additional potential causes of community-acquired pneumonia (CAP) is appropriate. The cochairs of the recently released American Thoracic Society and Infectious Diseases Society of America Guideline for Treatment of Adults with CAP offer their interpretation of this guideline's application to the evaluation and treatment of patients with COVID-19.
Thu May 07, 2020 03:00
Coronavirus disease 2019 has disrupted the lives of billions of persons worldwide. Emergencies can stimulate substantial investment of resources that catalyze impressive scientific accomplishments but can also lead to false promises and ethical breaches. The authors discuss how history shows the importance of treating early results with caution, because we are only beginning to understand severe acute respiratory syndrome coronavirus 2.
Thu May 07, 2020 03:00
Background:The new coronavirus, severe acute respiratory syndrome coronavirus-2 (SARS–CoV-2), has caused more than 210 000 deaths worldwide. However, little is known about the causes of death and the virus's pathologic features.Objective:To validate and compare clinical findings with data from medical autopsy, virtual autopsy, and virologic tests.Design:Prospective cohort study.Setting:Autopsies performed at a single academic medical center, as mandated by the German federal state of Hamburg for...
Wed May 06, 2020 03:00
Background:Health care workers (HCWs) are at risk for severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection.Purpose:To examine the burden of SARS-CoV-2, SARS-CoV-1, and Middle Eastern respiratory syndrome (MERS)-CoV on HCWs and risk factors for infection, using rapid and living review methods.Data Sources:Multiple electronic databases including the WHO Database of Publications on Coronavirus Disease and medRxiv preprint server (2003 through 27 March 2020, with ongoing surveillance...
Tue May 05, 2020 03:00
The supply chain for U.S. health care is really 5 different supply chains, and each one has its own problems and opportunities for improvement. This article explains what we're up against and what we can do about it.
Tue May 05, 2020 03:00
In Annals' first rapid, living systematic review, Chou and colleagues examined the burden of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), SARS-CoV-1, and Middle East respiratory syndrome coronavirus on health care workers and risk factors for infection. The editorialists discuss the role of these review types and describe the features they will look for when Annals is considering rapid and living reviews for publication.
Tue May 05, 2020 03:00
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