Surgery and radiation therapy (RT) are the main therapeutic options for curing patients suffering from cancer, with RT administered to over 50% of them [1]. Over the last few decades, the development of several radiosensitizing molecules that enhance the efficacy of RT for both local control and ablation of potential metastasis has taken place [2]. These molecules include nanoparticles, molecular targeted drugs, immunotherapy, aspirin, and statins [3-9]. Furthermore, a few drugs, still under development...
Colorectal cancers (CRCs) remain the most prevalent malignancies worldwide [1] with incidences increasing approximately by 22% over the past 10 years among patients < 50 years of age, primarily due to a trend in greater numbers of rectal and distal colon tumors [2]. Neoadjuvant concurrent chemo-radiotherapy (CCRT) prior to surgery has been recommended for patients with locally advanced rectal cancer since the addition of fluorouracil-based chemotherapy might sensitize cells to the local radiation...
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Care pathways (CPs) offer a proven method of systematically improving patient care. CPs are particularly helpful in complex clinical conditions where variation in care is a problem such as patients undergoing ...
Care pathways (CPs) are helpful in reducing unwanted variation in clinical care. Most studies of CPs show they improve clinical outcomes but there is little known about the long-term impact of CPs as part of a...
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Facial plastic surgery, including septorhinoplasty, aging face procedures, otoplasty, and oculoplastic procedures, has varying levels of evidence for the management of acute pain after surgery. This article discusses the available evidence in these procedures and discusses the authors’ recommendations for the treatment of postoperative pain, with a focus on decreasing the reliance on opioid pain medication.
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Monitoring vascular perfusion of transferred tissue is essential in reconstructive surgery to recognize early flap failure. The aim of this study was to evaluate the ability of a digital surface scanner to detect vascular perfusion disorders through the monitoring of skin colour changes. A total of 160 surface scans of the forearm skin were performed with a TRIOS 3D scanner. Vascular compromise was simulated at different time-points by intermittent occlusion of the blood supply to the forearm skin...
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Publication date: September 2020Source: Brain and Language, Volume 208Author(s): Jérôme Prado, Jessica Léone, Justine Epinat-Duclos, Emmanuel Trouche, Hugo Mercier
Publication date: September 2020Source: Brain and Language, Volume 208Author(s): Mikel Santesteban, Adam Zawiszewski, Anna Hatzidaki
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This is the case of a 76-year-old man admitted to hospital in a delirium state, previously diagnosed with a major depressive disorder at an age of 50 years, treated for years for chronic tension headache. The computed tomography of the head resulted negative. Inpatient laboratory tests revealed a mild hypercalcemia. Due to the progression of the disease (delirium state, dementia, tension headache, and depression), he was again admitted to hospital. The patient showed dysarthria, postural tremors,...
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