Τετάρτη 24 Ιουνίου 2020


Quality of life analysis of patients treated with cetuximab or cisplatin for locoregionally advanced squamous cell carcinoma of head and neck in the United States.
Related Articles Quality of life analysis of patients treated with cetuximab or cisplatin for locoregionally advanced squamous cell carcinoma of head and neck in the United States. Health Qual Life Outcomes. 2020 Jun 22;18(1):195 Authors: Aggarwal H, Punekar RS, Li L, Carter GC, Walker MS Abstract BACKGROUND: To compare quality of life of patients treated with cetuximab with or without radiation therapy (±RT) vs. cisplatin±RT for locoregionally...
Head and Neck
Wed Jun 24, 2020 13:20
A pain in the neck: Salmonella spp. as an unusual cause of a thyroid abscess. A case report and review of the literature.
Related Articles A pain in the neck: Salmonella spp. as an unusual cause of a thyroid abscess. A case report and review of the literature. BMC Infect Dis. 2020 Jun 22;20(1):436 Authors: AlYousef MK, Al-Sayed AA, Al Afif A, Alamoudi U, LeBlanc JM, LeBlanc R Abstract BACKGROUND: Thyroid gland infections are rare. Their incidence is estimated to be less than 1% in immunocompromised hosts. Most common pathogens isolated are Gram positive aerobic...
Head and Neck
Wed Jun 24, 2020 13:20
Optimization of Delivery of Pediatric Otolaryngology Surgical Antibiotic Prophylaxis.
Related Articles Optimization of Delivery of Pediatric Otolaryngology Surgical Antibiotic Prophylaxis. Otolaryngol Head Neck Surg. 2020 Jun 23;:194599820933191 Authors: Yalamanchi P, Parent A, Thorne M Abstract OBJECTIVES: There is limited evidence regarding use of routine perioperative antibiotics for pediatric otolaryngologic procedures. The objectives of this quality improvement study were (1) to characterize the otolaryngology case...
Head and Neck
Wed Jun 24, 2020 13:20
Cricopharyngeal Achalasia: Management and Associated Outcomes-A Scoping Review.
Related Articles Cricopharyngeal Achalasia: Management and Associated Outcomes-A Scoping Review. Otolaryngol Head Neck Surg. 2020 Jun 23;:194599820931470 Authors: Dewan K, Santa Maria C, Noel J Abstract OBJECTIVE: There is little consensus regarding the efficacy and safety of treatment options for cricopharyngeal (CP) achalasia. The purpose of this scoping review is to assess the literature regarding the various treatments for this disease....
Head and Neck
Wed Jun 24, 2020 13:20
Involvement of Laryngopharyngeal Reflux in Select Nonfunctional Laryngeal Diseases: A Systematic Review.
Related Articles Involvement of Laryngopharyngeal Reflux in Select Nonfunctional Laryngeal Diseases: A Systematic Review. Otolaryngol Head Neck Surg. 2020 Jun 23;:194599820933209 Authors: Lechien JR, Akst LM, Saussez S, Crevier-Buchman L, Hans S, Barillari MR, Calvo-Henriquez C, Bock JM, Carroll TL Abstract OBJECTIVES: To investigate the existing published evidence supporting the role of laryngopharyngeal reflux (LPR) in the development...
Head and Neck
Wed Jun 24, 2020 13:20
Narrowband Imaging for p16+ Unknown Primary Squamous Cell Carcinoma Prior to Transoral Robotic Surgery.
Related Articles Narrowband Imaging for p16+ Unknown Primary Squamous Cell Carcinoma Prior to Transoral Robotic Surgery. Otolaryngol Head Neck Surg. 2020 Jun 23;:194599820933204 Authors: Al-Mulki K, Hamilton J, Kaka AS, Boyce BJ, Baddour HM, El-Deiry M, Solares CA, Magliocca K, Summers K, Aiken A, Saba NF, Beitler JJ, Patel MR Abstract Our purpose was to assess the potential utility of narrowband imaging (NBI) as a tool in diagnosing and...
Head and Neck
Wed Jun 24, 2020 13:20
The Difficult Airway and Aerosol-Generating Procedures in COVID-19: Timeless Principles for Uncertain Times.
Related Articles The Difficult Airway and Aerosol-Generating Procedures in COVID-19: Timeless Principles for Uncertain Times. Otolaryngol Head Neck Surg. 2020 Jun 23;:194599820936615 Authors: Smith JD, Chen MM, Balakrishnan K, Sidell DR, di Stadio A, Schechtman SA, Brody RM, Kupfer RA, Rassekh CH, Brenner MJ Abstract The impact of the COVID-19 pandemic on otolaryngology practice is nowhere more evident than in acute airway management. Considerations...
Head and Neck
Wed Jun 24, 2020 13:20
National Trends in Surgical Resection of Vestibular Schwannomas.
Related Articles National Trends in Surgical Resection of Vestibular Schwannomas. Otolaryngol Head Neck Surg. 2020 Jun 23;:194599820932148 Authors: Ren Y, Sethi RKV, Stankovic KM Abstract OBJECTIVE: To characterize the national trend for surgical resection of vestibular schwannoma (VS) and to assess changes in demographics, length of stay (LOS), discharge patterns, and hospital charges. STUDY DESIGN: Population-based inpatient...
Head and Neck
Wed Jun 24, 2020 13:20
The Role of Age and Merkel Cell Polyomavirus in Oral Cavity Cancers.
Related Articles The Role of Age and Merkel Cell Polyomavirus in Oral Cavity Cancers. Otolaryngol Head Neck Surg. 2020 Jun 23;:194599820932553 Authors: Windon M, Fakhry C, Rooper L, Ha P, Schoppy D, Miles B, Koch W, Vosler P, Eisele D, D'Souza G Abstract The incidence of oral tongue cancer, the majority subsite of oral cavity cancer, is rising among young people with less exposure to tobacco and alcohol. Viral causes have been proposed,...
Head and Neck
Wed Jun 24, 2020 13:20
Subjective Visual Vertical Testing in Patients With Chronic Suppurative Otitis Media.
Related Articles Subjective Visual Vertical Testing in Patients With Chronic Suppurative Otitis Media. Otolaryngol Head Neck Surg. 2020 Jun 23;:194599820931491 Authors: da Costa Monsanto R, Kasemodel ALP, Tomaz A, de Oliveira Penido N Abstract OBJECTIVE: To analyze the results of the subjective visual vertical test using the "bucket method" in patients with chronic suppurative otitis media (CSOM). STUDY DESIGN: Cross-sectional,...
Head and Neck
Wed Jun 24, 2020 13:20
Meta-analysis Exploring Sinopulmonary Outcomes of Aspirin Desensitization in Aspirin-Exacerbated Respiratory Disease.
Related Articles Meta-analysis Exploring Sinopulmonary Outcomes of Aspirin Desensitization in Aspirin-Exacerbated Respiratory Disease. Otolaryngol Head Neck Surg. 2020 Jun 23;:194599820932137 Authors: Chaaban MR, Moffatt D, Wright AE, Cowthran JA, Hsu ES, Kuo YF Abstract OBJECTIVE: The objective of this study is to explore the sinopulmonary outcomes of aspirin desensitization through a systematic review and meta-analysis. DATA...
Head and Neck
Wed Jun 24, 2020 13:20
Identifying Type III Sulcus: Patient Characteristics and Endoscopic Findings.
Related Articles Identifying Type III Sulcus: Patient Characteristics and Endoscopic Findings. Otolaryngol Head Neck Surg. 2020 Jun 23;:194599820933208 Authors: Varelas EA, Paddle PM, Franco RA, Husain IA Abstract OBJECTIVE: Type III sulcus is a pathologic structural deformity of the vocal folds that is challenging to accurately diagnose without endoscopic examination under anesthesia. This study aims to further define the clinical presentation...
Head and Neck
Wed Jun 24, 2020 13:20
Patient-Reported Outcomes in Sinonasal and Skull Base Malignancy: An Assessment of Study Quality and Clinical Relevance.
Related Articles Patient-Reported Outcomes in Sinonasal and Skull Base Malignancy: An Assessment of Study Quality and Clinical Relevance. Am J Rhinol Allergy. 2020 Jun 22;:1945892420930967 Authors: Bolk KG, Roth KA, Sharma A, Crosby DL Abstract BACKGROUND: Sinonasal and skull base malignancies can cause significant adverse effects on functional status and survival. OBJECTIVE: The goal of this study was to systematically review...
Head and Neck
Wed Jun 24, 2020 13:20
Epigenetic Regulation of the Human Papillomavirus Life Cycle.
Related Articles Epigenetic Regulation of the Human Papillomavirus Life Cycle. Pathogens. 2020 Jun 18;9(6): Authors: Mac M, Moody CA Abstract Persistent infection with certain types of human papillomaviruses (HPVs), termed high risk, presents a public health burden due to their association with multiple human cancers, including cervical cancer and an increasing number of head and neck cancers. Despite the development of prophylactic vaccines,...
Head and Neck
Wed Jun 24, 2020 13:20
Diagnostic and Therapeutic Applications of Exosomes in Cancer with a Special Focus on Head and Neck Squamous Cell Carcinoma (HNSCC).
Related Articles Diagnostic and Therapeutic Applications of Exosomes in Cancer with a Special Focus on Head and Neck Squamous Cell Carcinoma (HNSCC). Int J Mol Sci. 2020 Jun 18;21(12): Authors: Ebnoether E, Muller L Abstract Exosomes are nanovesicles part of a recently described intercellular communication system. Their properties seem promising as a biomarker in cancer research, where more sensitive monitoring and therapeutic applications...
Head and Neck
Wed Jun 24, 2020 13:20
Double lumen endotracheal tube, flexible lightwand and ultrasound to safely carry out percutaneous tracheostomy.
Related Articles Double lumen endotracheal tube, flexible lightwand and ultrasound to safely carry out percutaneous tracheostomy. Geriatr Gerontol Int. 2020 06;20(6):647-648 Authors: Vargas M, Russo G, Servillo G PMID: 32537870 [PubMed - indexed for MEDLINE]
Head and Neck
Wed Jun 24, 2020 13:20
Completion of an Individualized Learning Plan for Otology-Related Milestone Subcompetencies Leads to Improved Otology Section Otolaryngology Training Exam Scores.
Related Articles Completion of an Individualized Learning Plan for Otology-Related Milestone Subcompetencies Leads to Improved Otology Section Otolaryngology Training Exam Scores. Otol Neurotol. 2019 12;40(10):1392-1398 Authors: Pennock M, Svrakic M, Bent JP Abstract OBJECTIVE: To examine the relationships among self-assessment of knowledge in otology via an individualized learning plan (ILP), otology milestone achievement rate, and otolaryngology...
Head and Neck
Wed Jun 24, 2020 13:20
High Altitude Alternobaric Facial Palsy: Case Series and Systematic Review of the Literature.
Related Articles High Altitude Alternobaric Facial Palsy: Case Series and Systematic Review of the Literature. Otol Neurotol. 2019 12;40(10):1378-1385 Authors: Cumming B, Matchett I, Meller C, Saxby A Abstract BACKGROUND: Alternobaric facial palsy (AFP) is a rare phenomenon which occurs in patients with Eustachian tube dysfunction, a dehiscent facial canal, and subsequent compression induced ischemic neuropraxia of the facial nerve upon exposure...
Head and Neck
Wed Jun 24, 2020 13:20
The International Index of Erectile Function (IIEF)-A Systematic Review of Measurement Properties.
Related Articles The International Index of Erectile Function (IIEF)-A Systematic Review of Measurement Properties. J Sex Med. 2019 07;16(7):1078-1091 Authors: Neijenhuijs KI, Holtmaat K, Aaronson NK, Holzner B, Terwee CB, Cuijpers P, Verdonck-de Leeuw IM Abstract INTRODUCTION: The International Index of Erectile Function (IIEF) is a patient-reported outcome measure to evaluate erectile dysfunction and other sexual problems in men. ...
Head and Neck
Wed Jun 24, 2020 13:20
Performance of the Vulnerable Elders Survey 13 screening tool in identifying cancer treatment modification after geriatric assessment in pre-treatment patients: A retrospective analysis.
Related Articles Performance of the Vulnerable Elders Survey 13 screening tool in identifying cancer treatment modification after geriatric assessment in pre-treatment patients: A retrospective analysis. J Geriatr Oncol. 2019 03;10(2):229-234 Authors: Rowbottom L, Loucks A, Jin R, Breunis H, Syed AT, Watt S, Timilshina N, Puts M, Yokom D, Berger A, Alibhai SMH Abstract PURPOSE: Geriatric assessment (GA) is recommended for older adults ≥ 70 years...
Head and Neck
Wed Jun 24, 2020 13:20
Demographic transition - Cancer trends in geriatric population of North India.
Related Articles Demographic transition - Cancer trends in geriatric population of North India. J Geriatr Oncol. 2019 03;10(2):362-364 Authors: Kansal S, Rao S Abstract Developing countries like India are witnessing a demographic transition resulting in population ageing. This population expansion will in future increase the burden of diseases more prevalent in older patients. Since cancer incidence increases with age, a surge in geriatric...
Head and Neck
Wed Jun 24, 2020 13:20
Misinformation about spinal manipulation and boosting immunity: an analysis of Twitter activity during the COVID-19 crisis.
Related Articles Misinformation about spinal manipulation and boosting immunity: an analysis of Twitter activity during the COVID-19 crisis. Chiropr Man Therap. 2020;28:34 Authors: Kawchuk G, Hartvigsen J, Harsted S, Nim CG, Nyirö L Abstract Background: Social media has become an increasingly important tool in monitoring the onset and spread of infectious diseases globally as well monitoring the spread of information about those diseases....
pubmed: frontiers immunology
Wed Jun 24, 2020 13:20
Pulsatilla chinensis saponins cause liver injury through interfering ceramide/sphingomyelin balance that promotes lipid metabolism dysregulation and apoptosis.
Related Articles Pulsatilla chinensis saponins cause liver injury through interfering ceramide/sphingomyelin balance that promotes lipid metabolism dysregulation and apoptosis. Phytomedicine. 2020 Jun 15;76:153265 Authors: Su D, Liao Z, Feng B, Wang T, Shan B, Zeng Q, Song J, Song Y Abstract BACKGROUND: P. chinensis saponins (PRS) are pentacyclic triterpenoid bioactive constituents from Pulsatilla chinensis (Bunge) Regel. In our previous...
pubmed: cell cycle arrest
Wed Jun 24, 2020 15:12
MALT-1 as a novel therapeutic target for adult T-cell leukemia.
Related Articles MALT-1 as a novel therapeutic target for adult T-cell leukemia. Eur J Haematol. 2020 Jun 23;: Authors: Ishikawa C, Mori N Abstract OBJECTIVES: T-cell receptor (TCR) signaling-induced activation of NF-κB requires assembly of the CARD11-BCL10-MALT-1 complex and IκB kinase (IKK). Gain-of-function alterations in this component of the TCR/NF-κB pathway are associated with the development of HTLV-1-driven adult T-cell leukemia...
pubmed: cell cycle arrest
Wed Jun 24, 2020 15:12
Head-to-head comparisons of Toxoplasma gondii and its near relative Hammondia hammondi reveal dramatic differences in the host response and effectors with species-specific functions.
Related Articles Head-to-head comparisons of Toxoplasma gondii and its near relative Hammondia hammondi reveal dramatic differences in the host response and effectors with species-specific functions. PLoS Pathog. 2020 Jun 23;16(6):e1008528 Authors: Wong ZS, Sokol-Borrelli SL, Olias P, Dubey JP, Boyle JP Abstract Toxoplasma gondii and Hammondia hammondi are closely-related coccidian intracellular parasites that differ in their ability to...
pubmed: cell cycle arrest
Wed Jun 24, 2020 15:12
Polo-like kinase 1 (Plk1) is a positive regulator of DNA replication in the Xenopus in vitro system.
Related Articles Polo-like kinase 1 (Plk1) is a positive regulator of DNA replication in the Xenopus in vitro system. Cell Cycle. 2020 Jun 23;:1-16 Authors: Ciardo D, Haccard O, Narassimprakash H, Chiodelli V, Goldar A, Marheineke K Abstract Polo-like kinase 1 (Plk1) is a cell cycle kinase essential for mitosis progression, but also important for checkpoint recovery and adaptation in response to DNA damage and replication stress. However,...
pubmed: cell cycle arrest
Wed Jun 24, 2020 15:12
Carvacrol Promotes Cell Cycle Arrest and Apoptosis through PI3K/AKT Signaling Pathway in MCF-7 Breast Cancer Cells.
Related Articles Carvacrol Promotes Cell Cycle Arrest and Apoptosis through PI3K/AKT Signaling Pathway in MCF-7 Breast Cancer Cells. Chin J Integr Med. 2020 Jun 22;: Authors: Mari A, Mani G, Nagabhishek SN, Balaraman G, Subramanian N, Mirza FB, Sundaram J, Thiruvengadam D Abstract OBJECTIVE: To examine the role of carvacrol in modulating PI3K/AKT signaling involved in human breast cancer pathogenesis using in vitro experimental model MCF-7...
pubmed: cell cycle arrest
Wed Jun 24, 2020 13:13
Functional genomics identifies new synergistic therapies for retinoblastoma.
Related Articles Functional genomics identifies new synergistic therapies for retinoblastoma. Oncogene. 2020 Jun 22;: Authors: Aubry A, Pearson JD, Huang K, Livne-Bar I, Ahmad M, Jagadeesan M, Khetan V, Ketela T, Brown KR, Yu T, Lu S, Wrana JL, Moffat J, Bremner R Abstract Local intravitreal or intra-arterial chemotherapy has improved therapeutic success for the pediatric cancer retinoblastoma (RB), but toxicity remains a major caveat....
pubmed: cell cycle arrest
Wed Jun 24, 2020 13:13
Exploiting replicative stress in gynecological cancers as a therapeutic strategy.
Related Articles Exploiting replicative stress in gynecological cancers as a therapeutic strategy. Int J Gynecol Cancer. 2020 Jun 22;: Authors: Ngoi NY, Sundararajan V, Tan DS Abstract Elevated levels of replicative stress in gynecological cancers arising from uncontrolled oncogenic activation, loss of key tumor suppressors, and frequent defects in the DNA repair machinery are an intrinsic vulnerability for therapeutic exploitation. The...
pubmed: cell cycle arrest
Wed Jun 24, 2020 13:13
Sophoridine exerts tumor-suppressive activities via promoting ESRRG-mediated β-catenin degradation in gastric cancer.
Related Articles Sophoridine exerts tumor-suppressive activities via promoting ESRRG-mediated β-catenin degradation in gastric cancer. BMC Cancer. 2020 Jun 22;20(1):582 Authors: Peng Z, Guan Q, Luo J, Deng W, Liu J, Yan R, Wang W Abstract BACKGROUND: As a natural alkaloid product isolated from Sophora alopecuroides. L, Sophoridine reshapes gastric cancer immune microenvironment via inhibiting chemotaxis and M2 polarization of tumor-associated...
pubmed: cell cycle arrest
Wed Jun 24, 2020 13:13
CHEK2 Mutation in Patient with Multiple Endocrine Glands Tumors. Case Report.
Related Articles CHEK2 Mutation in Patient with Multiple Endocrine Glands Tumors. Case Report. Int J Environ Res Public Health. 2020 Jun 18;17(12): Authors: Szeliga A, Pralat A, Witczak W, Podfigurna A, Wojtyla C, Kostrzak A, Meczekalski B Abstract BACKGROUND: Many studies show the occurrence of several multiple endocrine neoplasia syndromes caused by different mutations, for example, in MEN1 and RET genes. Nevertheless, there are less...
pubmed: cell cycle arrest
Wed Jun 24, 2020 13:13
BRCA1 mislocalization leads to aberrant DNA damage response in heterozygous ABRAXAS1 mutation carrier cells.
Related Articles BRCA1 mislocalization leads to aberrant DNA damage response in heterozygous ABRAXAS1 mutation carrier cells. Hum Mol Genet. 2019 12 15;28(24):4148-4160 Authors: Bose M, Sachsenweger J, Laurila N, Parplys AC, Willmann J, Jungwirth J, Groth M, Rapakko K, Nieminen P, Friedl TWP, Heiserich L, Meyer F, Tuppurainen H, Peltoketo H, Nevanlinna H, Pylkäs K, Borgmann K, Wiesmüller L, Winqvist R, Pospiech H Abstract Whilst heterozygous...
pubmed: cell cycle arrest
Wed Jun 24, 2020 13:13
Inhibition of spindle extension through the yeast S phase checkpoint is coupled to replication fork stability and the integrity of centromeric DNA.
Related Articles Inhibition of spindle extension through the yeast S phase checkpoint is coupled to replication fork stability and the integrity of centromeric DNA. Mol Biol Cell. 2019 10 15;30(22):2771-2789 Authors: Julius J, Peng J, McCulley A, Caridi C, Arnak R, See C, Nugent CI, Feng W, Bachant J Abstract Budding yeast treated with hydroxyurea (HU) activate the S phase checkpoint kinase Rad53, which prevents DNA replication forks from...
pubmed: cell cycle arrest
Wed Jun 24, 2020 13:13
Large Copy-Number Variants in UK Biobank Caused by Clonal Hematopoiesis May Confound Penetrance Estimates.
Related Articles Large Copy-Number Variants in UK Biobank Caused by Clonal Hematopoiesis May Confound Penetrance Estimates. Am J Hum Genet. 2020 Jun 17;: Authors: Tuke M, Tyrrell J, Ruth KS, Beaumont RN, Wood AR, Murray A, Frayling TM, Weedon MN, Wright CF Abstract Large copy-number variants (CNVs) are strongly associated with both developmental delay and cancer, but the type of disease depends strongly on when and where the mutation occurred,...
Rare Cancers
Wed Jun 24, 2020 15:07
Adrenocortical tumors in children.
Related Articles Adrenocortical tumors in children. Semin Pediatr Surg. 2020 Jun;29(3):150927 Authors: Kastenberg ZJ, Scaife ER Abstract Adrenocortical neoplasms are rare in childhood. Unlike their adult counterparts, they are often hormonally active and malignant. Despite being uncommon, adrenocortical neoplasms in children have significant associated morbidity and require complete surgical resection for effective management. Furthermore, the...
Rare Cancers
Wed Jun 24, 2020 13:08
Multiple primary tumors: a case report and review of the literature.
Related Articles Multiple primary tumors: a case report and review of the literature. BMC Musculoskelet Disord. 2020 Jun 22;21(1):394 Authors: Zhao Z, Sun K, Yan T, Wei R, Guo W Abstract BACKGROUND: Multiple primary tumors, especially quadruple primary neoplasms is extremely rare. Fibrous dysplasia (FD), osteosarcoma (OS), and giant cell tumor of bone (GCTB) are three bone tumors with low incidence while primary pulmonary meningioma is a rare...
Rare Cancers
Wed Jun 24, 2020 13:08
Controversies in the Workup and Surgical Management of Parotid Neoplasms.
Related Articles Controversies in the Workup and Surgical Management of Parotid Neoplasms. Otolaryngol Head Neck Surg. 2020 Jun 23;:194599820932512 Authors: Moore MG, Yueh B, Lin DT, Bradford CR, Smith RV, Khariwala SS Abstract OBJECTIVE: Parotid neoplasms are a rare heterogeneous group of tumors with varied clinical presentation and behavior. Here we provide an evidence-based review of the contemporary approach to evaluation and surgical management...
Rare Cancers
Wed Jun 24, 2020 13:08
A Rare Case of Glomus Tumor on the Mucosal Surface of Lower Lip.
Related Articles A Rare Case of Glomus Tumor on the Mucosal Surface of Lower Lip. J Investig Med High Impact Case Rep. 2020 Jan-Dec;8:2324709620936159 Authors: Naji Rad S, Najirad S, Rafiei R Abstract Glomus tumors are mesenchymal neoplasms derived from glomus bodies with rare presentations in the oral cavity. Glomus tumors present as a purple or pink vascular nodule or papule, sized <1 cm, and imitate vascular neoplasms such as hemangiopericytoma...
Rare Cancers
Wed Jun 24, 2020 13:08
HLA Class I Allele Expression and Clinical Outcome in De Novo Metastatic Prostate Cancer.
Related Articles HLA Class I Allele Expression and Clinical Outcome in De Novo Metastatic Prostate Cancer. Cancers (Basel). 2020 Jun 18;12(6): Authors: Stokidis S, Fortis SP, Kogionou P, Anagnostou T, Perez SA, Baxevanis CN Abstract The prognostic value of human leukocyte antigen (HLA) class I molecules in prostate cancer (PCa) remains unclear. Herein, we investigated the prognostic relevance of the most frequently expressed HLA-A alleles in...
Rare Cancers
Wed Jun 24, 2020 13:08
Rare Tumor-Normal Matched Whole Exome Sequencing Identifies Novel Genomic Pathogenic Germline and Somatic Aberrations.
Related Articles Rare Tumor-Normal Matched Whole Exome Sequencing Identifies Novel Genomic Pathogenic Germline and Somatic Aberrations. Cancers (Basel). 2020 Jun 18;12(6): Authors: Sprissler R, Perkins B, Johnstone L, Babiker HM, Chalasani P, Lau B, Hammer M, Mahadevan D Abstract Whole exome sequencing (WES) of matched tumor-normal pairs in rare tumors has the potential to identify genome-wide mutations and copy number alterations (CNAs). We...
Rare Cancers
Wed Jun 24, 2020 13:08
[Gastrointestinal tumors in older patients].
Related Articles [Gastrointestinal tumors in older patients]. Z Gastroenterol. 2020 Jun;58(6):564-576 Authors: Schulte N, Ebert MP, Reissfelder C, Härtel N Abstract Older patients (65 years and over) represent the majority of patients with a cancer diagnosis. For oesophageal carcinomas, the age peak is in the seventh to eighth decade of life. In gastric carcinoma, 1/3 of patients are older than 75 years and approximately 45 % of colon carcinoma...
Rare Cancers
Wed Jun 24, 2020 13:08
Primary transitional cell carcinoma of the fallopian tube: A case report and literature review.
Related Articles Primary transitional cell carcinoma of the fallopian tube: A case report and literature review. Medicine (Baltimore). 2020 May 29;99(22):e20499 Authors: Lee DH, Cho DH, Kim KM, Yim CY, Lee NR Abstract INTRODUCTION: Primary transitional cell carcinoma (TCC) of the fallopian tube is an extremely rare tumor. PATIENT CONCERNS: A 79-year-old woman presenting with vaginal discharge. DIAGNOSIS: Pelvic magnetic resonance...
Rare Cancers
Wed Jun 24, 2020 13:08
Chemical meningitis in children as a risk factor following craniopharyngioma resection - a case report.
Related Articles Chemical meningitis in children as a risk factor following craniopharyngioma resection - a case report. BMC Neurol. 2020 Feb 15;20(1):56 Authors: Chrościńska-Krawczyk M, Zienkiewicz E, Podkowiński A, Klatka M Abstract BACKGROUND: Craniopharyngiomas are defined by the WHO as "benign" tumours, but their location and surgical treatment may be associated with major complications, one being chemical meningitis. Although rare, especially...
Rare Cancers
Wed Jun 24, 2020 13:08
Management of cancer-related thrombosis in the era of direct oral anticoagulants: A comprehensive review of the 2019 ITAC-CME clinical practice guidelines. On behalf of the Groupe Francophone Thrombose et Cancer (GFTC).
Related Articles Management of cancer-related thrombosis in the era of direct oral anticoagulants: A comprehensive review of the 2019 ITAC-CME clinical practice guidelines. On behalf of the Groupe Francophone Thrombose et Cancer (GFTC). J Med Vasc. 2020 Feb;45(1):28-40 Authors: Rafii H, Frère C, Benzidia I, Crichi B, Andre T, Assenat E, Bournet B, Carpentier A, Connault J, Doucet L, Durant C, Emmerich J, Gris JC, Hij A, Le Hello C, Madelaine I, Messas E, Ndour...
Rare Cancers
Wed Jun 24, 2020 13:08
Cytohistology of morule in cribriform-morular variant of papillary thyroid carcinoma.
Related Articles Cytohistology of morule in cribriform-morular variant of papillary thyroid carcinoma. Malays J Pathol. 2019 Dec;41(3):339-343 Authors: Sakurai K, Onouchi T, Yamada S, Baba Y, Murata T, Tsukamoto T, Kuroda M, Urano M Abstract INTRODUCTION: Cribriform-morular variant (CMV) is a rare variant of papillary thyroid carcinoma. It frequently occurs in association with familial adenomatous polyposis (FAP), although some cases are sporadic....
Rare Cancers
Wed Jun 24, 2020 13:08
A new complex translocation (8;22;21)(q22;q12;q22) in RUNX1/RUNX1T1 acute myeloid leukaemia.
Related Articles A new complex translocation (8;22;21)(q22;q12;q22) in RUNX1/RUNX1T1 acute myeloid leukaemia. Malays J Pathol. 2019 Dec;41(3):333-338 Authors: Tay Za K, Shanmugam H, Chin EFM Abstract INTRODUCTION: Acute myeloid leukaemia (AML) with t(8;21)(q22;q22) producing RUNX1-RUNX1T1 rearrangement is a distinct sub-type which is usually associated with a favourable clinical outcome. Variant forms of t(8;21) are rare. Herein we describe...
Rare Cancers
Wed Jun 24, 2020 13:08
A radiological and histological comparison of two unusual adrenal incidentalomas.
Related Articles A radiological and histological comparison of two unusual adrenal incidentalomas. Malays J Pathol. 2019 Dec;41(3):327-331 Authors: Loong S, Selvarajan S, Khor LY Abstract INTRODUCTION: The increasing use of radiological imaging studies has given rise to 'incidentalomas'. CASE REPORT: We describe two unusual and diverse incidental adrenal gland lesions, an adenomatoid nodule and a mature ganglioneuroma. Both are deemed...
Rare Cancers
Wed Jun 24, 2020 13:08
Fulminant diabetes due to immune checkpoint inhibitors in the emergency department.
Related Articles Fulminant diabetes due to immune checkpoint inhibitors in the emergency department. Am J Emerg Med. 2020 02;38(2):408.e3-408.e4 Authors: Peyrony O, Ellouze S, Fontaine JP, Mohamadou I, Zafrani L Abstract Immune checkpoint inhibitors (ICIs) are of growing importance in new cancer therapies, exposing patients to various and potentially severe immune-related adverse events and placing emergency physicians on the front line when...
Rare Cancers
Wed Jun 24, 2020 13:08
Ectopic Cushing Syndrome: A Rare Cause of Electrolyte Derangements.
Related Articles Ectopic Cushing Syndrome: A Rare Cause of Electrolyte Derangements. Am J Med. 2020 05;133(5):e173-e176 Authors: Fanous N, Schwartz C, Gargus N, Casella JL PMID: 31606493 [PubMed - indexed for MEDLINE]
Rare Cancers
Wed Jun 24, 2020 13:08
Genetic variants in taste-related genes and risk of pancreatic cancer.
Related Articles Genetic variants in taste-related genes and risk of pancreatic cancer. Mutagenesis. 2019 12 19;34(5-6):391-394 Authors: Gentiluomo M, Lu Y, Canzian F, Campa D Abstract Pancreatic ductal adenocarcinoma is an aggressive and relatively rare cancer with a dismal 5-year survival rate and a clear genetic background. Genetic variants in taste receptors and taste-related genes have been associated with a variety of human traits and...
Rare Cancers
Wed Jun 24, 2020 13:08
[Chorangioma of the Placenta - A Rare Placental Cause of Fetal High Output Cardiac Failure].
Related Articles [Chorangioma of the Placenta - A Rare Placental Cause of Fetal High Output Cardiac Failure]. Z Geburtshilfe Neonatol. 2020 Apr;224(2):103-106 Authors: Ziemann M, Apostolidou S, Dum D, Hecher K, Singer D, Tavares de Sousa M Abstract Chorangiomas of the placenta, benign tumors of chorionic tissue, are a rare placental cause of adverse fetal and maternal outcomes. We describe the case of a large placental chorangioma leading to...
Rare Cancers
Wed Jun 24, 2020 13:08
Spontaneous Radial Nerve Palsy due to an Unrecognized Myofibroma: A Case Report.
Related Articles Spontaneous Radial Nerve Palsy due to an Unrecognized Myofibroma: A Case Report. JBJS Case Connect. 2019 Apr-Jun;9(2):e0284 Authors: Hinchcliff KM, Rogers J, Sarohia D, Hornick J, Szabo RM Abstract CASE: A 33-year-old woman presented with a six-month history of spontaneous radial nerve palsy and no identified lesion on imaging. She underwent operative exploration where an hourglass deformity was seen and resected. Pathology...
Rare Cancers
Wed Jun 24, 2020 13:08
Ibrutinib-associated sever skin toxicity: A case of multiple inflamed skin lesions and cellulitis in a 68-year-old male patient with relapsed chronic lymphocytic leukemia - Case report and literature review.
Related Articles Ibrutinib-associated sever skin toxicity: A case of multiple inflamed skin lesions and cellulitis in a 68-year-old male patient with relapsed chronic lymphocytic leukemia - Case report and literature review. J Oncol Pharm Pract. 2020 Mar;26(2):487-491 Authors: Ghasoub R, Albattah A, Elazzazy S, Alokka R, Nemir A, Alhijji I, Taha R Abstract INTRODUCTION: Ibrutinib is an oral inhibitor of Bruton's tyrosine kinase that is used...
Rare Cancers
Wed Jun 24, 2020 13:08
Intra-articular Osteoid Osteoma of the Distal Femur Treated with Osteochondral Grafting: A Report of 2 Cases.
Related Articles Intra-articular Osteoid Osteoma of the Distal Femur Treated with Osteochondral Grafting: A Report of 2 Cases. JBJS Case Connect. 2019 Apr-Jun;9(2):e0211 Authors: Monroe EJ, Chambers CC, Davoodian A, Cho SJ, Motamedi D, Allen CR Abstract CASE: Intra-articular osteoid osteoma (IAOO) is a relatively rare entity and can pose a therapeutic challenge due to proximity to the cartilage surface. We present 2 cases of subchondral osteoid...
Rare Cancers
Wed Jun 24, 2020 13:08
An advanced c-MET-amplified NSCLC patient that was treated with crizotinib.
Related Articles An advanced c-MET-amplified NSCLC patient that was treated with crizotinib. J Oncol Pharm Pract. 2020 Mar;26(2):474-477 Authors: Yilmaz M, Mese SG, Cil I, Zirtiloglu A Abstract INTRODUCTION: c-MET is a tyrosine kinase receptor, which is encoded in part by mesenchymal-epidermal transition (MET) exon 14. Mutations in the MET gene can cause increased c-MET signaling and oncogenic stimulation. Although c-MET mutation is rare, it...
Rare Cancers
Wed Jun 24, 2020 13:08
Upper limbs myo-fasciitis and polyarthritis in ovarian cancer.
Related Articles Upper limbs myo-fasciitis and polyarthritis in ovarian cancer. Joint Bone Spine. 2019 Nov;86(6):797 Authors: Chouk M, Hecquet S, Verhoeven F, Prati C, Wendling D PMID: 31153921 [PubMed - indexed for MEDLINE]
Rare Cancers
Wed Jun 24, 2020 13:08
Recurrent YAP1-MAML2 and YAP1-NUTM1 fusions in poroma and porocarcinoma.
Related Articles Recurrent YAP1-MAML2 and YAP1-NUTM1 fusions in poroma and porocarcinoma. J Clin Invest. 2019 05 30;129(9):3827-3832 Authors: Sekine S, Kiyono T, Ryo E, Ogawa R, Wakai S, Ichikawa H, Suzuki K, Arai S, Tsuta K, Ishida M, Sasajima Y, Goshima N, Yamazaki N, Mori T Abstract Poroma is a benign skin tumor exhibiting terminal sweat gland duct differentiation. The present study aimed to explore the potential role of gene fusions in...
Rare Cancers
Wed Jun 24, 2020 13:08
Desmoplastic Fibroma: A Rare Pathological Midshaft Femoral Fracture Treated With Resection, Acute Shortening, and Re-lengthening: A Case Report.
Related Articles Desmoplastic Fibroma: A Rare Pathological Midshaft Femoral Fracture Treated With Resection, Acute Shortening, and Re-lengthening: A Case Report. JBJS Case Connect. 2019 Apr-Jun;9(2):e0022 Authors: Stevens J, Moin S, Salter D, Patton JT Abstract CASE: We report a rare case of desmoplastic fibroma (DF) of the midshaft femur presenting as a pathological fracture. This rare benign bone tumor was treated with an acute en bloc excision...
Rare Cancers
Wed Jun 24, 2020 13:08
Multiple round pulmonary nodules in a patient with breast cancer.
Related Articles Multiple round pulmonary nodules in a patient with breast cancer. Pol Arch Intern Med. 2019 05 31;129(5):348-350 Authors: Wakuliński J, Jeśkiewicz M, Szołkowska M, Jakubowska L, Radzikowska E PMID: 30758315 [PubMed - indexed for MEDLINE]
Rare Cancers
Wed Jun 24, 2020 13:08
Concomitant Intraductal Papillary Mucinous Neoplasm in Pancreatic Ductal Adenocarcinoma Is an Independent Predictive Factor for the Occurrence of New Cancer in the Remnant Pancreas.
Related Articles Concomitant Intraductal Papillary Mucinous Neoplasm in Pancreatic Ductal Adenocarcinoma Is an Independent Predictive Factor for the Occurrence of New Cancer in the Remnant Pancreas. Ann Surg. 2020 05;271(5):941-948 Authors: Matsuda R, Miyasaka Y, Ohishi Y, Yamamoto T, Saeki K, Mochidome N, Abe A, Ozono K, Shindo K, Ohtsuka T, Kikutake C, Nakamura M, Oda Y Abstract OBJECTIVE: To determine the factors predicting the subsequent...
Rare Cancers
Wed Jun 24, 2020 13:08

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