Abstract Purpose Meningiomas are mainly benign tumors, though a considerable proportion shows aggressive behaviors histologically consistent with atypia/anaplasia. Histopathological grading is usually assessed through invasive procedures, which is not always feasible due to the inaccessibility of the lesion or to treatment contraindications. Therefore, we propose a multi-parametric MRI assessment as a predictor of meningioma histopathological...
Wed Jun 24, 2020 03:00
189 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human physiology These pubmed results were generated on 2020/06/24PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Jun 24, 2020 15:05
Perioperative Management and Outcomes of Hyperthyroid Patients Unable to Tolerate Antithyroid Drugs.
Related Articles Perioperative Management and Outcomes of Hyperthyroid Patients Unable to Tolerate Antithyroid Drugs. World J Surg. 2020 Jun 22;: Authors: Hsieh LB, Yen TWF, Dream S, Patel D, Evans DB, Wang TS Abstract BACKGROUND: Prior to thyroidectomy for hyperthyroidism, it is recommended that patients are managed with antithyroid drugs (ATDs) and rendered euthyroid to decrease the risk of thyroid storm. However, not all patients tolerate...
Wed Jun 24, 2020 15:03
Abstract Human growth is a complex trait determined by genetic factors in combination with external stimuli, including environment, nutrition and hormonal status. In the past, several genome-wide association studies (GWAS) have collectively identified hundreds of genetic variants having a putative effect on determining adult height in different worldwide populations. Theoretically, a valuable approach to better understand the mechanisms of complex traits as adult height is to...
Wed Jun 24, 2020 03:00
Related Articles A multidisciplinary approach for managing the infraglottic difficult airway in the setting of the Coronavirus pandemic. Oper Tech Otolayngol Head Neck Surg. 2020 Jun;31(2):128-137 Authors: Nouraei SAR, Girgis M, Shorthouse J, El-Boghdadly K, Ahmad I Abstract Management of a difficult airway caused by pathology below the glottis is high-risk and requires a shared approach to airway planning and surgical treatment. Access to the...
Wed Jun 24, 2020 15:00
Related Articles Involvement of Laryngopharyngeal Reflux in Select Nonfunctional Laryngeal Diseases: A Systematic Review. Otolaryngol Head Neck Surg. 2020 Jun 23;:194599820933209 Authors: Lechien JR, Akst LM, Saussez S, Crevier-Buchman L, Hans S, Barillari MR, Calvo-Henriquez C, Bock JM, Carroll TL Abstract OBJECTIVES: To investigate the existing published evidence supporting the role of laryngopharyngeal reflux (LPR) in the development of the...
Wed Jun 24, 2020 15:00
Related Articles MicroRNA-155 acts as a diagnostic and prognostic biomarker for oesophageal squamous cell carcinoma. Artif Cells Nanomed Biotechnol. 2020 Dec;48(1):977-982 Authors: Zheng YJ, Liang TS, Wang J, Zhao JY, Zhai SN, Yang DK, Wang LD Abstract MicroRNA-155 is over-expressed in many human cancers, but researches on its association with malignant oesophageal squamous cell carcinoma (ESCC) are limited. The aim of the present study...
Wed Jun 24, 2020 14:43
Abstract Objectives Determine whether the insertion site of the recurrent laryngeal nerve (RLN) occurs at a predictable distance from the midline trachea, to help guide safe dissection during thyroid surgery. Design Prospective clinical trial. At the inferior edge of the cricoid cartilage, we measured the distance from mildline trachea to the RLN insertion site. Setting Single institution. Participants 50 consecutive patients undergoing thyroid surgery. Main outcome measures...
Tue Jun 23, 2020 20:51
ABSTRACT Ultrasound (US) has become an integral part of the practice of medicine due in part to its soft tissue resolution, cost effectiveness, ability to measure vessel flow and, perhaps most relevant to head and neck surgeons, ease of use in the clinical setting in conjunction with fine needle aspiration (FNA).
Tue Jun 23, 2020 17:40
Related Articles Influence of the introduction of a triphenylphosphine group on the anticancer activity of a copper complex. J Inorg Biochem. 2020 May 11;210:111102 Authors: Li S, Zhao J, Guo Y, Mei Y, Yuan B, Gan N, Zhang J, Hu J, Hou H Abstract Aiming at obtaining new copper complexes with good cytotoxicity against cancer cells, triphenylphosphine (TPP) was introduced to obtain insight into the influence of the co-ligands. In this paper, two...
Wed Jun 24, 2020 14:36
Publication date: Available online 24 June 2020Source: Ultrasound in Medicine & BiologyAuthor(s): Hua Wang, Xiaoxue Yang, Jin Hou, Xiaopeng Li, Lei Sun, Jue Jiang, Qi Zhou
Wed Jun 24, 2020 14:33
Related Articles Destruction of ERP responses to deviance in an auditory oddball paradigm in amyloid infusion mice with memory deficits. PLoS One. 2020;15(3):e0230277 Authors: Kim B, Shin J, Kim Y, Choi JH Abstract The amyloid-β (Aβ) oligomer is considered one of the major pathogens responsible for neuronal and synaptic loss in Alzheimer's disease (AD) brains. Although the neurotoxic mechanisms of Aβ have been widely investigated, experimental...
Wed Jun 24, 2020 14:32
Publication date: September 2020Source: Biomedicine & Pharmacotherapy, Volume 129Author(s): Nan Gao, Baoguo Ye
Wed Jun 24, 2020 14:29
Publication date: September 2020Source: Biomedicine & Pharmacotherapy, Volume 129Author(s): Quan Qi, Yanlun Zhu, Gang Liu, Zhize Yuan, Haiyan Li, Qiang Zhao
Wed Jun 24, 2020 14:29
Positionspapier: Anwendung von Biologika bei chronischer Rhinosinusitis mit Polyposis nasi (CRSwNP) im deutschen Gesundheitssystem – Empfehlungen des Ärzteverbandes Deutscher Allergologen (AeDA) und der AGs Klinische Immunologie, Allergologie und Umweltmedizin und Rhinologie und Rhinochirurgie der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Halschirurgie (DGHNOKHC). Laryngorhinootologie. 2020 Jun 23;: Authors: Klimek L, Förster-Ruhrmann U, Becker S,...
Wed Jun 24, 2020 22:31
Tue Jun 23, 2020 21:19
Objectives Examine the prevalence and risk of metastasis in thyroid cancers and management outcomes. Study design Retrospective analysis of the National Cancer Database, 2004–2014. Methods The study population included adult (≥ 18 years) patients with thyroid cancer. Analysis included multivariate logistic regression and Cox hazard ratio modeling. Results A total of 152,979 patients were included. Distant metastasis was reported in 1,867 (1.22%) patients. The distribution of metastatic...
Tue Jun 23, 2020 21:08
Objectives/Hypothesis To describe the magnetic resonance imaging (MRI) characteristics of the pericranial flap, changes in the pericranial flap thickness over time, presence of frontal sinus opacification, and presence of frontal lobe herniation into the nasal cavity. Study Design Retrospective case series. Methods Seventeen consecutive endoscopic craniofacial resections with pericranial flap reconstruction performed at a tertiary hospital from 2010 to 2019 were reviewed. Sixty‐eight...
Tue Jun 23, 2020 21:07
Related Articles Automatic diagnosis for cysts and tumors of both jaws on panoramic radiographs using a deep convolution neural network. Dentomaxillofac Radiol. 2020 Jun 23;:20200185 Authors: Kwon O, Yong TH, Kang SR, Kim JE, Huh KH, Heo MS, Lee SS, Choi SC, Yi WJ Abstract OBJECTIVE: The purpose of this study was to automatically diagnose odontogenic cysts and tumors of both jaws on panoramic radiographs using deep learning. We proposed...
Wed Jun 24, 2020 18:21
Related Articles A Case of Paraneoplastic Cerebellar Degeneration that Preceded the Diagnosis of Classical Hodgkin's Lymphoma by 16 Months. Am J Case Rep. 2020 Jun 23;21:e922342 Authors: Arratibel N, Sobejano E, Moran JC, Diaz LG, Blázquez A, Baile M, Veiga Á, Caballero MD, García-Sanz R Abstract BACKGROUND Paraneoplastic cerebellar degeneration (PCD) is a rare condition that can present as an acute or subacute cerebellar syndrome. PCD is most...
Wed Jun 24, 2020 18:25
Related Articles Sleeve Gastrectomy Combined with Nissen Fundoplication as a Single Surgical Procedure, Is It Really Safe? A Case Report. Am J Case Rep. 2020 Jun 23;21:e923543 Authors: Martines G, Musa N, Aquilino F, Picciariello A, Altomare DF Abstract BACKGROUND Laparoscopic sleeve gastrectomy (LSG) has become the most common surgical procedure performed in bariatric surgery. Large hiatal hernias and Barrett's esophagus are the only contraindications...
Wed Jun 24, 2020 14:25
Related Articles Functional characterization of TMEM127 variants reveals novel insights into its membrane topology and trafficking. J Clin Endocrinol Metab. 2020 Jun 23;: Authors: Flores SK, Deng Y, Cheng Z, Zhang X, Tao S, Saliba A, Chu I, Burnichon N, Gimenez-Roqueplo AP, Wang E, Aguiar RCT, Dahia PLM Abstract CONTEXT: TMEM127 is a poorly known tumor suppressor gene associated with pheochromocytomas, paragangliomas and renal carcinomas. Our...
Wed Jun 24, 2020 15:49
Related Articles Experimental realization of dynamic fluence field optimization for proton computed tomography. Phys Med Biol. 2020 Jun 23;: Authors: Dickmann J, Sarosiek C, Rykalin V, Pankuch M, Rit S, Detrich N, Coutrakon GB, Johnson RP, Schulte RW, Parodi K, Landry G, Dedes G Abstract Proton computed tomography (pCT) has high accuracy and dose efficiency in producing spatial maps of the relative stopping power (RSP) required for treatment...
Wed Jun 24, 2020 15:49
Related Articles Immune-checkpoint inhibitors and metastatic prostate cancer therapy: Learning by making mistakes. Cancer Treat Rev. 2020 Jun 10;88:102057 Authors: Claps M, Mennitto A, Guadalupi V, Sepe P, Stellato M, Zattarin E, Gillessen SS, Sternberg CN, Berruti A, De Braud FGM, Verzoni E, Procopio G Abstract Despite advances in metastatic prostate cancer therapy, expected survival for patients in the castration-resistant phase of disease...
Wed Jun 24, 2020 15:49
Related Articles The Feasibility and Acceptability of a Cognitive Behavioral Therapy-based intervention for Patients with Advanced Colorectal Cancer. J Pain Symptom Manage. 2020 Jun 20;: Authors: Teo I, Tan YP, Finkelstein EA, Yang GM, Pan FT, Lew HYF, Tan EKW, Ong SYK, Cheung YB Abstract Context/ objectives: Advanced colorectal cancer and its treatment can bring about challenges associated with psychological distress. The primary aims of this...
Wed Jun 24, 2020 15:49
Related Articles Shared decision-making for the management of small renal masses - development and acceptability testing of a novel patient decision aid. Can Urol Assoc J. 2020 Jun 16;: Authors: McAlpine K, Breau RH, Stacey D, Knee C, Jewett MAS, Violette PD, Richard PO, Cagiannos I, Morash C, Lavallée LT Abstract INTRODUCTION: Shared decision-making incorporates patient's values and preferences to achieve high-quality decisions. The objective...
Wed Jun 24, 2020 15:49
Related Articles Perception of the 2020 SARS-CoV-2 pandemic among medical professionals in Germany: results from a nationwide online survey. Emerg Microbes Infect. 2020 Jun 23;:1-30 Authors: Paffenholz P, Peine A, Hellmich M, Paffenholz SV, Martin L, Luedde M, Haverkamp M, Roderburg C, Marx G, Heidenreich A, Trautwein C, Luedde T, Loosen SH Abstract Background: The COVID-19 pandemic represents an unprecedented global challenge. While drastic...
Wed Jun 24, 2020 15:49
Related Articles Human blood PIG-A mutation and micronucleated reticulocyte flow cytometric assays: Method optimization and evaluation of intra- and inter-subject variation. Environ Mol Mutagen. 2020 Jun 22;: Authors: Torous DK, Avlasevich SL, Khattab MG, Baig A, Saubermann LJ, Chen Y, Bemis JC, Lovell DP, Walker VE, MacGregor JT, Dertinger SD Abstract We previously described flow cytometry-based methods for scoring the incidence of micronucleated...
Wed Jun 24, 2020 14:21
Related Articles Novel treatment paradigms in acute myeloid leukemia. Clin Pharmacol Ther. 2020 Jun 23;: Authors: Khanal N, Upadhyay Banskota S, Bhatt VR Abstract Acute myeloid leukemia (AML) is a heterogeneous disease marked by the presence of several driver mutations and molecular subgroups even in a single patient. The genetic and molecular heterogeneity is also reflected by a progressive shift from a morphologic classification to one informed...
Wed Jun 24, 2020 14:21
Related Articles Systemic Pharmacokinetics of Oxaliplatin After Intraperitoneal Administration by Electrostatic Pressurized Intraperitoneal Aerosol Chemotherapy (ePIPAC) in Patients with Unresectable Colorectal Peritoneal Metastases in the CRC-PIPAC Trial. Ann Surg Oncol. 2020 Jun 22;: Authors: Lurvink RJ, Tajzai R, Rovers KP, Wassenaar ECE, Moes DAR, Pluimakers G, Boerma D, Burger JWA, Nienhuijs SW, de Hingh IHJT, Deenen MJ Abstract BACKGROUND:...
Wed Jun 24, 2020 14:21
Related Articles Towards new horizons: characterization, classification and implications of the tumour antigenic repertoire. Nat Rev Clin Oncol. 2020 Jun 22;: Authors: Haen SP, Löffler MW, Rammensee HG, Brossart P Abstract Immune-checkpoint inhibition provides an unmatched level of durable clinical efficacy in various malignancies. Such therapies promote the activation of antigen-specific T cells, although the precise targets of these T cells...
Wed Jun 24, 2020 14:21
Related Articles Prognostic factors in patients with vulvar cancer: the VULCAN study. Int J Gynecol Cancer. 2020 Jun 22;: Authors: Zapardiel I, Iacoponi S, Coronado PJ, Zalewski K, Chen F, Fotopoulou C, Dursun P, Kotsopoulos IC, Jach R, Buda A, Martinez-Serrano MJ, Grimm C, Fruscio R, Garcia E, Sznurkowski JJ, Ruiz C, Noya MC, Barazi D, Diez J, Diaz De la Noval B, Bartusevicius A, De Iaco P, Otero M, Diaz M, Haidopoulos D, Franco S, Blecharz P, Zuñiga MA, Rubio...
Wed Jun 24, 2020 14:21
Related Articles MRI of benign hyperplasia in the nasopharynx: is there an association with Epstein-Barr virus? Clin Radiol. 2020 Jun 19;: Authors: Ai QY, King AD, So TY, Lam WKJ, Mo FKF, Tse IOL, Woo JKS, Chan KCA Abstract AIM: To evaluate whether there is an association between persistently positive plasma Epstein-Barr virus (EBV) DNA and the presence and the change in benign hyperplasia. MATERIALS AND METHODS: One hundred and seventeen...
Wed Jun 24, 2020 14:21
Related Articles Parenchymal lung disease in adult onset Still's disease: an emergent marker of disease severity-characterisation and predictive factors from Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale (GIRRCS) cohort of patients. Arthritis Res Ther. 2020 Jun 22;22(1):151 Authors: Ruscitti P, Berardicurti O, Iacono D, Pantano I, Liakouli V, Caso F, Emmi G, Grembiale RD, Cantatore FP, Atzeni F, Perosa F, Scarpa R, Guggino G, Ciccia F, Barile...
Wed Jun 24, 2020 14:21
Related Articles Radiobiological model-based approach to determine the potential of dose-escalated robust intensity-modulated proton radiotherapy in reducing gastrointestinal toxicity in the treatment of locally advanced unresectable pancreatic cancer of the head. Radiat Oncol. 2020 Jun 22;15(1):157 Authors: Raturi VP, Hojo H, Hotta K, Baba H, Takahashi R, Rachi T, Nakamura N, Zenda S, Motegi A, Tachibana H, Ariji T, Motegi K, Nakamura M, Okumura M, Hirano Y,...
Wed Jun 24, 2020 14:21
Related Articles cGAS-STING, an important pathway in cancer immunotherapy. J Hematol Oncol. 2020 Jun 22;13(1):81 Authors: Jiang M, Chen P, Wang L, Li W, Chen B, Liu Y, Wang H, Zhao S, Ye L, He Y, Zhou C Abstract Cytosolic DNA sensing, the cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) pathway, is an important novel role in the immune system. Multiple STING agonists were developed for cancer therapy study with great results...
Wed Jun 24, 2020 14:21
Related Articles Building towards common psychosocial measures in U.S. cohort studies: principal investigators' views regarding the role of religiosity and spirituality in human health. BMC Public Health. 2020 Jun 22;20(1):973 Authors: Shields AE, Balboni TA Abstract BACKGROUND: The goal of this study was to understand prospective cohort study Principal Investigators' (PIs') attitudes regarding the importance of religion and spirituality (R/S)...
Wed Jun 24, 2020 14:21
Related Articles Advancing Cancer Research in Africa Through Early-Career Awards: The BIG Cat Initiative. J Glob Oncol. 2019 04;5:1-8 Authors: Vogel AL, Freeman JA, Duncan K, Alaro J, Welch JJ, Rodrigues B, Vanderpuye V, Harford JB, Williams M Abstract PURPOSE: The burden of cancer in Africa is growing rapidly, and increased cancer research on the continent is a critical component of an effective response. In 2010, the US National Cancer Institute,...
Wed Jun 24, 2020 14:21
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