Publication date: September 2020Source: Clinical Neurology and Neurosurgery, Volume 196Author(s): Fei Zeng, Mengye Zhu, Quan Wan, Yi Yan, Changxi Li, Yong Zhang
Wed Jun 24, 2020 17:48
Abstract Cisplatin is a widely used anti-cancer drug used to treat a variety of cancer types. One of the side effects of this life-saving drug is irreversible ototoxicity, resulting in permanent hearing loss in many patients. In order to understand why cisplatin is particularly toxic to the inner ear, we compared the hearing loss and cochlear uptake of cisplatin to that of two related drugs, carboplatin and oxaliplatin. These three drugs are similar in that each contains a core...
Wed Jun 24, 2020 03:00
44 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2020/06/24PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Jun 24, 2020 17:33
44 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2020/06/24PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Jun 24, 2020 13:30
Publication date: Available online 24 June 2020Source: Sleep MedicineAuthor(s): Kelly Guichard, Theo Michaud, Imad Ghorayeb
Wed Jun 24, 2020 17:33
Publication date: Available online 24 June 2020Source: Sleep MedicineAuthor(s): Shangda Li, Hetong Zhou, Yueran Yu, Hailong Lyu, Tingting Mou, Gongde Shi, Shaohua Hu, Manli Huang, Jianbo Hu, Yi Xu
Wed Jun 24, 2020 17:33
Iron deficiency anemia is common and worldwide distributed, particularly among females; however, it can also occur among males. Iron deficiency anemia is commonly associated with thrombocytosis; little is known about the effect of iron therapy (oral or intravenous) on other hematological parameters. We report a 29-year-old male patient with iron deficiency anemia, who received oral iron replacement therapy and developed neutropenia which recovered spontaneously 1 month later. Case Rep Oncol 2020;13:721–724
Wed Jun 24, 2020 17:01
The prognosis of locally advanced gastric cancer is poor even if radical gastrectomy with D2 lymphadenectomy is followed by adjuvant chemotherapy. Hence, neoadjuvant chemotherapy is performed to try to improve the prognosis, as it can significantly downstage the tumor and safely improve the R0 resection rate of patients. Herein, we report a case of locally advanced gastric cancer with pancreatic invasion and gastric outlet obstruction that showed a pathological complete response after neoadjuvant...
Wed Jun 24, 2020 17:01
Primary hemochromatosis is an inherited disorder, and the homeostatic iron regulator (HFE) gene C282Y mutation is a common cause of hemochromatosis in Europe. We are reporting a case of a 56-year-old female known to have hemochromatosis with the HFE gene C282Y mutation with a serum ferritin level of 482 μg/L who underwent heart and liver T2* MRI which showed no evidence of iron overload – neither in the heart nor in the liver. This indicates that there is a discrepancy between serum ferritin and...
Wed Jun 24, 2020 17:01
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm, classically described as a triphasic disease. However, little is known about risk factors for developing CML. Currently, ionizing radiation is the only established risk factor. Here, we report on a 37-year-old man treated for tuberculosis; 2 years later, he developed CML in a chronic phase. We would like to shed light on tuberculosis as a possible risk factor for CML. Case Rep Oncol 2020;13:708–711
Wed Jun 24, 2020 17:00
25 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: epilepsy treatment These pubmed results were generated on 2020/06/24PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Jun 24, 2020 17:15
25 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: epilepsy treatment These pubmed results were generated on 2020/06/24PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Jun 24, 2020 13:46
320 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: upper respiratory tract infection These pubmed results were generated on 2020/06/24PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Jun 24, 2020 17:09
320 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: upper respiratory tract infection These pubmed results were generated on 2020/06/24PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Jun 24, 2020 13:07
Publication date: September 2020Source: International Immunopharmacology, Volume 86Author(s): Cheng Luo, Junxing Chen, Lingwu Chen
Wed Jun 24, 2020 16:58
Publication date: September 2020Source: International Immunopharmacology, Volume 86Author(s): Yifan Wu, Zhanghong Wang, Xin Fu, Zeng Lin, Kehe Yu
Wed Jun 24, 2020 16:58
Publication date: September 2020Source: International Immunopharmacology, Volume 86Author(s): Xiu-Fang Huang, Jia-Lin Zhang, Dan-Ping Huang, Ai-Si Huang, Hui-Ting Huang, Qiong Liu, Xiao-Hong Liu, Hui-Li Liao
Wed Jun 24, 2020 16:58
Publication date: September 2020Source: International Immunopharmacology, Volume 86Author(s): Sha Tang, Qian Ning, Ling Yang, Zhongcheng Mo, Shengsong Tang
Wed Jun 24, 2020 16:58
Publication date: September 2020Source: International Immunopharmacology, Volume 86Author(s): Razieh Tavakoli Oliaee, Iraj Sharifi, Mehdi Bamorovat, Alireza Keyhani, Zahra Babaei, Ehsan Salarkia, Rahele Tavakoly, Ahmad Khosravi, Mahshid Mostafavi, Fatemeh Sharifi, Seyed Mohammad Mousavi
Wed Jun 24, 2020 16:58
Publication date: September 2020Source: International Immunopharmacology, Volume 86Author(s): Hwi-Ho Lee, Eungyeong Jang, Shin-Young Kang, Ji-Sun Shin, Hee-Soo Han, Tae-Woo Kim, Da Hye Lee, Jang-Hoon Lee, Dae Sik Jang, Kyung-Tae Lee
Wed Jun 24, 2020 16:58
Publication date: September 2020Source: International Immunopharmacology, Volume 86Author(s): Sanjiv Singh, Shantanu Singh
Wed Jun 24, 2020 16:58
55 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Proc Natl Acad Sci U S A"[jour] These pubmed results were generated on 2020/06/24PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Jun 24, 2020 16:58
Related Articles Comparison of antibiotic prescribing records in two UK primary care electronic health record systems: cohort study using CPRD GOLD and CPRD Aurum databases. BMJ Open. 2020 Jun 22;10(6):e038767 Authors: Gulliford MC, Sun X, Anjuman T, Yelland E, Murray-Thomas T Abstract OBJECTIVES: We aimed to evaluate recording of antibiotic prescribing from two primary care electronic health record systems. DESIGN: Cohort study. ...
Wed Jun 24, 2020 16:56
Related Articles A novel patient-reported outcome monitoring with clinical feedback system in bariatric surgery care: study protocol, design and plan for evaluation. BMJ Open. 2020 Jun 22;10(6):e037685 Authors: Hegland PA, Aasprang A, Kolotkin RL, Moltu C, Tell GS, Andersen JR Abstract BACKGROUND: Consultations before and after bariatric surgery should include structured assessments of patients' health-related quality of life (HRQOL) and mental...
Wed Jun 24, 2020 16:56
Related Articles Physiotherapists' pain attitudes and beliefs towards chronic low back pain and their association with treatment selection: a cross-sectional study. BMJ Open. 2020 Jun 22;10(6):e037159 Authors: Alshehri MA, Alzahrani H, Alotaibi M, Alhowimel A, Khoja O Abstract OBJECTIVES: The main aim of this study was to investigate physiotherapists' pain attitudes and beliefs towardss non-specific chronic low back pain (NSCLBP) and identify...
Wed Jun 24, 2020 16:56
Related Articles Assessing the transparency of informed consent in feasibility and pilot studies: a single-centre quality assurance study protocol. BMJ Open. 2020 Jun 22;10(6):e036226 Authors: Khan MI, Holek M, Bdair F, Mbuagbaw L, Eldridge SM, Chan CL, Campbell MJ, Bond CM, Hopewell S, Lancaster GA, Thabane L Abstract INTRODUCTION: Pilot/feasibility studies assess the feasibility of conducting a larger study. Although researchers ought to communicate...
Wed Jun 24, 2020 16:56
Related Articles How have predictors, moderators, mediators, treatment response, remission and resistance been defined and measured in randomised controlled trials for adolescent depression? A scoping review protocol. BMJ Open. 2020 Jun 22;10(6):e036171 Authors: Courtney D, Watson P, Chan BWC, Bennett KJ, Neprily K, Zentner T, Rodak T, Narrandes R, Szatmari P Abstract INTRODUCTION: Among randomised controlled trials for depressed adolescents,...
Wed Jun 24, 2020 16:56
Related Articles Psychometric properties of the German version of the Clinician-Administered PTSD Scale for DSM-5 (CAPS-5) in clinical routine settings: study design and protocol of a multitrait-multimethod study. BMJ Open. 2020 Jun 22;10(6):e036078 Authors: Spies JP, Woud ML, Kessler H, Rau H, Willmund GD, Köhler K, Herpertz S, Blackwell SE, Bovin M, Marx BP, Cwik JC Abstract INTRODUCTION: The aim of this study is to investigate the diagnostic...
Wed Jun 24, 2020 16:56
Related Articles Safety of tranexamic acid in thrombotic adverse events and seizure in patients with haemorrhage: a protocol for a systematic review and meta-analysis. BMJ Open. 2020 Jun 22;10(6):e036020 Authors: Murao S, Nakata H, Yamakawa K Abstract INTRODUCTION: Tranexamic acid (TXA) is a synthetic derivative of the amino acid lysine that inhibits fibrinolysis by blocking lysine-binding sites on plasminogen, which contribute to reduced bleeding,...
Wed Jun 24, 2020 16:56
Related Articles The EX-FRAIL CKD trial: a study protocol for a pilot randomised controlled trial of a home-based EXercise programme for pre-frail and FRAIL, older adults with Chronic Kidney Disease. BMJ Open. 2020 Jun 22;10(6):e035344 Authors: Nixon AC, Bampouras TM, Gooch HJ, Young HML, Finlayson KW, Pendleton N, Mitra S, Brady ME, Dhaygude AP Abstract INTRODUCTION: Frailty is highly prevalent in adults with chronic kidney disease (CKD) and...
Wed Jun 24, 2020 16:56
Related Articles Electronic cigarette use among university students aged 18-24 years in New Zealand: results of a 2018 national cross-sectional survey. BMJ Open. 2020 Jun 22;10(6):e035093 Authors: Wamamili B, Wallace-Bell M, Richardson A, Grace RC, Coope P Abstract OBJECTIVES: To examine electronic cigarette use, reasons for use and perceptions of harm among university students. DESIGN: Cross-sectional study. SETTING: University...
Wed Jun 24, 2020 16:56
Related Articles Variations in patterns of care across neonatal units and their associations with outcomes in very preterm infants: the French EPIPAGE-2 cohort study. BMJ Open. 2020 Jun 22;10(6):e035075 Authors: Pierrat V, Burguet A, Marchand-Martin L, Cambonie G, Coquelin A, Roze JC, Durox M, Guillois B, Morgan AS, Kaminski M, Neurodevelopmental care study group of EPIPAGE-2 Abstract OBJECTIVES: To describe patterns of care for very preterm...
Wed Jun 24, 2020 16:56
Related Articles Disturbing medical findings in war-related traumatic amputation patients: a clinical descriptive study from Gaza. BMJ Open. 2020 Jun 22;10(6):e034648 Authors: Heszlein-Lossius HE, Ismail A, Al-Borno Y, Shaqqoura S, Skaik N, Hinnawi IA, Matar M, Gilbert M Abstract OBJECTIVES: The aim of this study was to explore possible long-term negative health effects of injuries sustained by modern weaponry. SETTING: The study was...
Wed Jun 24, 2020 16:56
Related Articles Relationships between sites of abdominal pain and the organs involved: a prospective observational study. BMJ Open. 2020 Jun 22;10(6):e034446 Authors: Yamashita S, Tago M, Katsuki NE, Nishi TM, Yamashita SI Abstract OBJECTIVES: Abdominal pain is one of the most frequent chief complaints in primary care settings. The aim of the present study was to determine the positive likelihood ratios (PLRs) and negative likelihood ratios...
Wed Jun 24, 2020 16:56
Related Articles Systematic review protocol for assessing central auditory functions of Alzheimer's disease and its preclinical stages. BMJ Open. 2020 Jun 22;10(6):e033342 Authors: Jayakody DMP, Tarawneh HY, Menegola HK, Yiannos JM, Friedland PL, Wilson WJ, Martins RN, Sohrabi HR Abstract INTRODUCTION: A number of studies have reported an association between peripheral hearing impairment, central auditory processing and Alzheimer's disease (AD)...
Wed Jun 24, 2020 16:56
Related Articles Antenatal care booking within the first trimester of pregnancy and its associated factors among pregnant women residing in an urban area: a cross-sectional study in Debre Berhan town, Ethiopia. BMJ Open. 2020 Jun 22;10(6):e032960 Authors: Kolola T, Morka W, Abdissa B Abstract OBJECTIVE: This study aimed to assess antenatal care (ANC) booking within the first trimester of pregnancy and its associated factors among urban dwellers...
Wed Jun 24, 2020 16:56
Related Articles Augmentation of Scarred Vocal Folds With Centrifuged and Emulsified Autologous Fat Grafts. Otolaryngol Head Neck Surg. 2020 Jun 23;:194599820932836 Authors: Salmerón-González E, García-Vilariño E, Llópez-Carratalá I, Collado-Martin D, María Perolada-Valmaña J, Armengot-Carceller M Abstract OBJECTIVE: To review the results of a series of patients with glottic insufficiency caused by scarred vocal folds who underwent injection...
Wed Jun 24, 2020 16:55
Condition: Postoperative PainInterventions: Procedure: Suprascapular Nerve Block; Procedure: Axillary Nerve Block; Procedure: posterior cord block; Procedure: General anesthesiaSponsors: Bassant M. Abdelhamid; Cairo UniversityNot yet recruiting
Wed Jun 24, 2020 16:55
Conditions: Oropharynx Squamous Cell Carcinoma; Larynx Squamous Cell Carcinoma; Hypopharynx Squamous Cell Carcinoma; Oral Cavity Squamous Cell CarcinomaIntervention: Biological: IO102Sponsor: Cliniques universitaires Saint-Luc- Université Catholique de LouvainRecruiting
Wed Jun 24, 2020 16:55
Conditions: Cancer of the Head and Neck; Oropharynx Cancer; HPV Positive Oropharyngeal Squamous Cell Carcinoma; Throat CarcinomaIntervention: Drug: Cisplatin injectionSponsor: University of Missouri-ColumbiaNot yet recruiting
Wed Jun 24, 2020 16:55
Related Articles ATLAS: a Snakemake workflow for assembly, annotation, and genomic binning of metagenome sequence data. BMC Bioinformatics. 2020 Jun 22;21(1):257 Authors: Kieser S, Brown J, Zdobnov EM, Trajkovski M, McCue LA Abstract BACKGROUND: Metagenomics studies provide valuable insight into the composition and function of microbial populations from diverse environments; however, the data processing pipelines that rely on mapping reads to...
Wed Jun 24, 2020 16:50
Related Articles NLRX1 knockout aggravates lipopolysaccharide (LPS)-induced heart injury and attenuates the anti-LPS cardioprotective effect of CYP2J2/11,12-EET by enhancing activation of NF-κB and NLRP3 inflammasome. Eur J Pharmacol. 2020 Jun 20;:173276 Authors: Zhao G, Wang X, Edwards S, Dai M, Li J, Wu L, Xu R, Han J, Yuan H Abstract NLRX1 weakens lipopolysaccharide (LPS)-induced NF-κB activation on immune cells. Cytochrome P450 epoxygenase...
Wed Jun 24, 2020 16:46
Related Articles Safety and Efficacy of Blue Light Laser Treatment in Hereditary Hemorrhagic Telangiectasia. Lasers Surg Med. 2020 Jun 23;: Authors: Bertlich M, Kashani F, Weiss BG, Wiebringhaus R, Ihler F, Freytag S, Gires O, Kühnel T, Haubner F Abstract BACKGROUND AND OBJECTIVES: Hereditary hemorrhagic telangiectasia (HHT) is a hereditary condition that is associated with arteriovenous malformations. A common site for these malformations is...
Wed Jun 24, 2020 16:46
Related Articles Histone deacetylase 6 inhibitor ACY1215 ameliorates mitochondrial dynamic and function injury in hepatocytes by activating AMPK signaling pathway in acute liver failure mice. Histol Histopathol. 2020 Jun 23;:18237 Authors: Chen Q, Wang Y, Jiao F, Shi C, Pei M, Wang L, Gong Z Abstract Acute liver failure (ALF) is often accompanied by dynamic and functional disorders of mitochondria in hepatocytes. The histone deacetylase 6 inhibitor...
Wed Jun 24, 2020 16:41
Publication date: Available online 23 June 2020Source: Journal of VoiceAuthor(s): Yu Sakaguchi, Takeharu Kanazawa, Ayako Okui, Mayu Hirosaki, Ujimoto Konomi, Taisuke Sotome, Nahoko Tashiro, Miyuki Kurihara, Takumi Omae, Yosuke Nakayama, Ayumi Yamamoto, Ayane Sato, Kiyoshi Misawa, Yusuke Watanabe
Wed Jun 24, 2020 16:40
Publication date: Available online 23 June 2020Source: Journal of VoiceAuthor(s): Madeleine P. Strohl, Christopher D. Dwyer, Yue Ma, Clark A. Rosen, Sarah L. Schneider, VyVy N. Young
Wed Jun 24, 2020 16:40
Related Articles Alcohol consumption before pregnancy causes detrimental fetal development and maternal metabolic disorders. Sci Rep. 2020 Jun 22;10(1):10054 Authors: Lee YJ, Kim JY, Lee DY, Park KJ, Kim GH, Kim JE, Roh GS, Lim JY, Koo S, Lim NK, Park HY, Kim WH Abstract Alcohol consumption before or during pregnancy poses serious health risks to the fetus; however, the underlying mechanisms involved remain obscure. Here, we investigated whether...
Wed Jun 24, 2020 16:27
Related Articles Acute β-adrenoceptor mediated glucose clearance in brown adipose tissue; a distinct pathway independent of functional insulin signaling. Mol Metab. 2019 12;30:240-249 Authors: Olsen JM, Åslund A, Bokhari MH, Hutchinson DS, Bengtsson T Abstract OBJECTIVE: β-adrenoceptor mediated activation of brown adipose tissue (BAT) has been associated with improvements in metabolic health in models of type 2 diabetes and obesity due to...
Wed Jun 24, 2020 16:27
Related Articles Response to Letter to the Editor: Lavender products associated with premature thelarche and prepubertal gynecomastia: Case reports and EDC activities. J Clin Endocrinol Metab. 2020 Jun 23;: Authors: Ramsey JT, Diaz A, Naidu A, Korach KS PMID: 32575119 [PubMed - as supplied by publisher]
Wed Jun 24, 2020 16:25
Related Articles Pain in Patients with Type 2 Diabetes-related Polyneuropathy is Associated with Vascular Events and Mortality. J Clin Endocrinol Metab. 2020 Jun 23;: Authors: Lapin BR, Pantalone KM, Milinovich A, Morrison S, Schuster A, Boulos F, Johnson K, Thakore NJ Abstract PURPOSE: Type 2 diabetes related polyneuropathy (DPN) is associated with increased vascular events and mortality, but determinants and outcomes of pain in DPN are poorly...
Wed Jun 24, 2020 16:25
Related Articles Functional characterization of TMEM127 variants reveals novel insights into its membrane topology and trafficking. J Clin Endocrinol Metab. 2020 Jun 23;: Authors: Flores SK, Deng Y, Cheng Z, Zhang X, Tao S, Saliba A, Chu I, Burnichon N, Gimenez-Roqueplo AP, Wang E, Aguiar RCT, Dahia PLM Abstract CONTEXT: TMEM127 is a poorly known tumor suppressor gene associated with pheochromocytomas, paragangliomas and renal carcinomas. Our...
Wed Jun 24, 2020 16:25
Related Articles Anogenital distance in healthy Infants:Method-, age- and sex-related reference ranges. J Clin Endocrinol Metab. 2020 Jun 23;: Authors: Fischer MB, Ljubicic ML, Hagen CP, Thankamony A, Ong K, Hughes I, Jensen TK, Main KM, Petersen JH, Busch AS, Upners EN, Sathyanarayana S, Swan SH, Juul A Abstract CONTEXT: The use of anogenital distance (AGD) in clinical and epidemiological settings is increasing; however, sex-specific reference...
Wed Jun 24, 2020 16:25
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