Genetic correlations between traits can strongly impact evolutionary responses to selection, and may thus impose constraints on adaptation. Theoretical and empirical work has made it clear that, without strong linkage, genetic correlations at evolutionary equilibrium result from an interplay of correlated pleiotropic effects of mutations, and correlational selection favoring combinations of trait values. However, it is not entirely clear how the strength of stabilizing selection influences this compromise...
Wed Jun 24, 2020 03:00
114 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: ALCOHOL These pubmed results were generated on 2020/06/24PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Jun 24, 2020 16:25
Related Articles Performance of brief ICF-sleep disorders and obesity core set in obstructive sleep apnea patients. Respir Res. 2020 Jun 22;21(1):156 Authors: Xie L, Wu Q, Hu W, Li W, Xiang G, Hao S, Guo C, Jiang H, Wu X, Wu X, Li S Abstract BACKGROUND: Clinical questionnaires are mainly applied as screening tools for identification of the Obstructive sleep apnea (OSA) patients. Little attention has been paid to assess the body functions and...
Wed Jun 24, 2020 16:19
Related Articles Assessing the Impact of the COVID-19 Outbreak on the Attitudes and Practice of Italian Oncologists Toward Breast Cancer Care and Related Research Activities. JCO Oncol Pract. 2020 Jun 23;:OP2000297 Authors: Poggio F, Tagliamento M, Di Maio M, Martelli V, De Maria A, Barisione E, Grosso M, Boccardo F, Pronzato P, Del Mastro L, Lambertini M Abstract PURPOSE: To investigate the impact of the COVID-19 outbreak on the attitudes and...
Wed Jun 24, 2020 16:18
Related Articles YES1 amplification confers trastuzumab-emtansine (T-DM1) resistance in HER2-positive cancer. Br J Cancer. 2020 Jun 23;: Authors: Wang L, Wang Q, Xu P, Fu L, Li Y, Fu H, Quan H, Lou L Abstract BACKGROUND: Trastuzumab-emtansine (T-DM1), one of the most potent HER2-targeted drugs, shows impressive efficacy in patients with HER2-positive breast cancers. However, resistance inevitably occurs and becomes a critical clinical problem....
Wed Jun 24, 2020 16:18
Related Articles Improving Safety of MRI in Patients with Deep Brain Stimulation Devices. Radiology. 2020 Jun 23;:192291 Authors: Boutet A, Chow CT, Narang K, Elias GJB, Neudorfer C, Germann J, Ranjan M, Loh A, Martin AJ, Kucharczyk W, Steele CJ, Hancu I, Rezai AR, Lozano AM Abstract MRI is a valuable clinical and research tool for patients undergoing deep brain stimulation (DBS). However, risks associated with imaging DBS devices have...
Wed Jun 24, 2020 16:14
Related Articles Clinical Relevance of Multiparametric MRI Assessment of Cervical Cord Damage in Multiple Sclerosis. Radiology. 2020 Jun 23;:200430 Authors: Bonacchi R, Pagani E, Meani A, Cacciaguerra L, Preziosa P, De Meo E, Filippi M, Rocca MA Abstract Background In multiple sclerosis (MS), knowledge about how spinal cord abnormalities translate into clinical manifestations is incomplete. Comprehensive, multiparametric MRI studies are...
Wed Jun 24, 2020 16:14
Related Articles Prediction of Total Knee Replacement and Diagnosis of Osteoarthritis by Using Deep Learning on Knee Radiographs: Data from the Osteoarthritis Initiative. Radiology. 2020 Jun 23;:192091 Authors: Leung K, Zhang B, Tan J, Shen Y, Geras KJ, Babb JS, Cho K, Chang G, Deniz CM Abstract Background The methods for assessing knee osteoarthritis (OA) do not provide enough comprehensive information to make robust and accurate outcome...
Wed Jun 24, 2020 16:14
Related Articles The Role of Multiparametric US of the Liver for the Evaluation of Nonalcoholic Steatohepatitis. Radiology. 2020 Jun 23;:192665 Authors: Sugimoto K, Moriyasu F, Oshiro H, Takeuchi H, Abe M, Yoshimasu Y, Kasai Y, Sakamaki K, Hara T, Itoi T Abstract Background Nonalcoholic steatohepatitis (NASH) is diagnosed with histopathologic testing, but noninvasive surrogate markers are desirable for screening patients who are at high...
Wed Jun 24, 2020 16:14
Related Articles Patient-Reported Outcomes in Sinonasal and Skull Base Malignancy: An Assessment of Study Quality and Clinical Relevance. Am J Rhinol Allergy. 2020 Jun 22;:1945892420930967 Authors: Bolk KG, Roth KA, Sharma A, Crosby DL Abstract BACKGROUND: Sinonasal and skull base malignancies can cause significant adverse effects on functional status and survival. OBJECTIVE: The goal of this study was to systematically review...
Wed Jun 24, 2020 16:09
In recent decades, several new diseases have emerged in different geographical areas, with pathogens including Ebola virus, Zika virus, Nipah virus, and coronaviruses (CoVs). Recently, a new type of viral infection emerged in Wuhan City, China, and initial genomic sequencing data of this virus do not match with previously sequenced CoVs, suggesting a novel CoV strain (2019-nCoV), which has now been termed severe acute respiratory syndrome CoV-2 (SARS-CoV-2). Although coronavirus disease 2019 (COVID-19)...
Wed Jun 24, 2020 15:30
Abstract Introduction Recent molecular characterization of gliomas has uncovered somatic gene variation and DNA methylation changes that are associated with etiology, prognosis, and therapeutic response. Here we describe genomic profiling of gliomas assessed for associations between genetic mutations and patient outcomes, including overall survival (OS) and recurrence-free survival (RFS). ...
Wed Jun 24, 2020 03:00
Related Articles Diep Flap Volume Augmentation: Literature Review and "Calzone" Flap Shaping Technique. J Plast Reconstr Aesthet Surg. 2020 May 26;: Authors: Pompei B, Farhadi J Abstract Breast reconstruction with DIEP flap is a well-accepted and well-established technique for autologous breast reconstruction. In the past, this reconstructive option was typically offered to a limited group of patients as previous surgeries or low BMI were considered...
Wed Jun 24, 2020 15:58
Related Articles Serial measurements of facial asymmetry using a wooden tongue depressor in patients with congenital microtia. J Plast Reconstr Aesthet Surg. 2020 May 06;: Authors: Kim A, Kim S, Lee H, Oh KS Abstract BACKGROUND AND OBJECTIVES: Congenital microtia may be associated with hemifacial microsomia, but little is known about their correlation and development with aging. Historically, facial asymmetry is easily assessed by observing...
Wed Jun 24, 2020 15:58
Related Articles Analysis of Selection of Recipient Vein, Number of Outflows, Style and Technique in Head and Neck Venous Anastomosis and a Proposed Algorithm. J Plast Reconstr Aesthet Surg. 2020 May 26;: Authors: Acartürk TO, Bengür FB Abstract Surgeons have preferential ways of performing venous anastomosis in head and neck microsurgery. However, controversies exist regarding the superiority of each method. This study aims to determine the...
Wed Jun 24, 2020 15:58
Publication date: Available online 24 June 2020Source: European Journal of Surgical OncologyAuthor(s): Aditi Bhatt, Naoual Barkin, Witold Gertych, Praveen Kammar, Loma Parikh, Sandeep Sheth, Sakina Shaikh, Mojgan Devouassoux-Shisheboran, Olivier Glehen
Wed Jun 24, 2020 15:52
Publication date: Available online 24 June 2020Source: European Journal of Surgical OncologyAuthor(s): Zhening Zhang, Siyuan Cheng, Jifang Gong, Ming Lu, Jun Zhou, Xiaotian Zhang, Jian Li, Lin Shen, Zhi Peng
Wed Jun 24, 2020 15:52
Publication date: Available online 24 June 2020Source: European Journal of Surgical OncologyAuthor(s): Zhi Zhu, Yingbo Gong, Huimian Xu
Wed Jun 24, 2020 15:52
Publication date: Available online 24 June 2020Source: European Journal of Surgical OncologyAuthor(s): Monica Ramello, Riccardo A. Audisio
Wed Jun 24, 2020 15:52
Publication date: Available online 24 June 2020Source: European Journal of Surgical OncologyAuthor(s): Jose Ignacio Albergo, German Luis Farfalli, Miguel Angel Ayerza, Lucas Eduardo Ritacco, Luis Alberto Aponte-Tinao
Wed Jun 24, 2020 15:52
Publication date: Available online 24 June 2020Source: European Journal of Surgical OncologyAuthor(s): Sara van Bekkum, Bert P.M. ter Braak, Peter W. Plaisier, Joost van Rosmalen, Marian B.E. Menke-Pluijmers, Pieter J. Westenend
Wed Jun 24, 2020 15:52
Publication date: Available online 24 June 2020Source: European Journal of Surgical OncologyAuthor(s): Kotaro Sugawara, Hiroharu Yamashita, Yasuhiro Okumura, Koichi Yagi, Susumu Aikou, Yasuyuki Seto
Wed Jun 24, 2020 15:52
Publication date: Available online 23 June 2020Source: European Journal of Surgical OncologyAuthor(s): Yingbo Gong, Siwei Pan, Xin Wang, Guolian Zhu, Huimian Xu, Zhi Zhu
Wed Jun 24, 2020 15:52
Publication date: Available online 23 June 2020Source: European Journal of Surgical OncologyAuthor(s): Edward Willems, Mathieu D'Hondt
Wed Jun 24, 2020 15:52
Related Articles Breast Cancer Diagnosis in Coronavirus-Era: Alert From Italy. Front Oncol. 2020;10:938 Authors: Vanni G, Pellicciaro M, Materazzo M, Palombi L, Buonomo OC PMID: 32574281 [PubMed - as supplied by publisher]
Wed Jun 24, 2020 15:49
Related Articles Conducting Phase I Trials During the SARS-Coronavirus-2 Outbreak: About Science and Care. Front Oncol. 2020;10:926 Authors: Dipasquale A, Persico P, Lorenzi E, Bertossi M, Santoro A, Simonelli M PMID: 32574280 [PubMed - as supplied by publisher]
Wed Jun 24, 2020 15:49
Related Articles Treatment Strategies for Cancer Patients in Post-Peak of the Novel Coronavirus Disease (COVID-19) Period in China. Front Oncol. 2020;10:925 Authors: Liu B, Mo H, Ma F PMID: 32574279 [PubMed - as supplied by publisher]
Wed Jun 24, 2020 15:49
Related Articles A Primary Mediastinal Large B-Cell Lymphoma Patient With COVID-19 Infection After Intensive Immunochemotherapy: A Case Report. Front Oncol. 2020;10:924 Authors: Li Q, Zhu F, Xiao Y, Liu T, Liu X, Wu G, Zhang L Abstract Background: The outbreak of coronavirus disease 2019 (COVID-19) had become a global public health event. Lymphoma patients need to be distinguished from the general population because of their deficient immune...
Wed Jun 24, 2020 15:49
Related Articles Rethinking the Optimal Duration of Immune Checkpoint Inhibitors in Non-small Cell Lung Cancer Throughout the COVID-19 Pandemic. Front Oncol. 2020;10:862 Authors: Friedlaender A, Kim C, Addeo A Abstract Immune checkpoint inhibitors (ICPIs) have revolutionized the management and prognosis of fit patients with advanced non-small cell lung cancer (NSCLC). Recently, the publication of 5-year survival rates has cemented the role of...
Wed Jun 24, 2020 15:49
Publication date: July 2020Source: American Journal of Infection Control, Volume 48, Issue 7Author(s):
Wed Jun 24, 2020 15:39
Publication date: July 2020Source: American Journal of Infection Control, Volume 48, Issue 7Author(s): Tina Z. Wang, Kindra N. White, Jillian Villani Scarr, Matthew S. Simon, David P. Calfee
Wed Jun 24, 2020 15:39
Publication date: July 2020Source: American Journal of Infection Control, Volume 48, Issue 7Author(s):
Wed Jun 24, 2020 15:39
Publication date: July 2020Source: American Journal of Infection Control, Volume 48, Issue 7Author(s):
Wed Jun 24, 2020 15:39
Publication date: July 2020Source: American Journal of Infection Control, Volume 48, Issue 7Author(s):
Wed Jun 24, 2020 15:39
Publication date: July 2020Source: American Journal of Infection Control, Volume 48, Issue 7Author(s):
Wed Jun 24, 2020 15:39
Publication date: Available online 23 June 2020Source: European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): François Rubin, Jean-François Vellin, Julie Berkaoui, Wared Al Assaf, Angelo Pennica, Benoit Girard, Patrick Hoarau, Philippe Pescatori, Marie Dupre, Serge Bensoussan, Philippe Vurpillot, Nicolas Challut, Ollivier Laccourreye
Wed Jun 24, 2020 15:36
Related Articles Severe acute respiratory syndrome coronavirus-2 in post-laryngectomy patients: case series of four patients. J Laryngol Otol. 2020 Jun 23;:1-7 Authors: Coleman H, Sutherland J, Calder N PMID: 32571439 [PubMed - as supplied by publisher]
Wed Jun 24, 2020 15:35
Publication date: 1 September 2020Source: Behavioural Brain Research, Volume 393Author(s): David Checknita, Megha Bendre, Tomas J. Ekström, Erika Comasco, Jari Tiihonen, Sheilagh Hodgins, Kent W. Nilsson
Wed Jun 24, 2020 15:31
Publication date: Available online 24 June 2020Source: Auris Nasus LarynxAuthor(s): Yuma Matsumoto, Hidenori Yokoi, Tetsuya Ikeda, Michitsugu Kawada, Koichiro Saito
Wed Jun 24, 2020 15:28
Publication date: Available online 24 June 2020Source: Auris Nasus LarynxAuthor(s): Merve Bayri, Ayça Çiprut
Wed Jun 24, 2020 15:28
Related Articles Retraction: Greater analgesic effect with intermittent compared with continuous mode of lumbar plexus block for total hip arthroplasty: a randomized controlled trial. Reg Anesth Pain Med. 2020 Jun 22;: Authors: PMID: 32571846 [PubMed - as supplied by publisher]
Wed Jun 24, 2020 15:27
Related Articles Clinicopathologic factors and preoperative ultrasonographic characteristics for predicting central lymph node metastasis in papillary thyroid microcarcinoma: a single center retrospective study. Braz J Otorhinolaryngol. 2020 Jun 04;: Authors: Jiwang L, Yahong L, Kai L, Bo H, Yuejiao Z, Haotian W, Tao Y Abstract INTRODUCTION: The treatment of papillary thyroid microcarcinoma remains controversial. Central lymph node metastasis...
Wed Jun 24, 2020 15:17
Related Articles Mean platelet volume and neutrophil to lymphocyte ratio in patients with tinnitus: a case-control study. Braz J Otorhinolaryngol. 2020 Jun 04;: Authors: Yildiz S, Karaca H, Toros SZ Abstract INTRODUCTION: Different theories have been proposed on the etiology of tinnitus, including metabolic and audiologic causes. We suggest that mean platelet volume and neutrophil to lymphocyte ratio levels change in tinnitus, indicating microcirculatory...
Wed Jun 24, 2020 15:17
Related Articles The changes of endotracheal tube intracuff pressures after ear and head and neck surgery-related positions: a prospective observational study. Braz J Otorhinolaryngol. 2020 Jun 04;: Authors: Kara H, Hundur D, Doruk C, Buyuk D, Cansever G, Salviz EA, Camci E Abstract INTRODUCTION: The cuff of an endotracheal tube seals the airway to facilitate positive-pressure ventilation and reduce subglottic secretion aspiration. However,...
Wed Jun 24, 2020 15:17
Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00449A, PaperRatish R Nair, M Raju, Snehasish Debnath, Riya Ghosh, Pabitra Baran ChatterjeeDevelopment of receptors that can detect as well as treat cyanide in aqueous sample is an indispensable job for environmental protection. Herein, we present bulk-solvent free and instant green synthesis...The content of this RSS Feed (c) The Royal Society of Chemistry
Wed Jun 24, 2020 02:00
3221 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2020/06/24PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Jun 24, 2020 15:15
Related Articles Histone deacetylase 6 inhibitor ACY1215 ameliorates mitochondrial dynamic and function injury in hepatocytes by activating AMPK signaling pathway in acute liver failure mice. Histol Histopathol. 2020 Jun 23;:18237 Authors: Chen Q, Wang Y, Jiao F, Shi C, Pei M, Wang L, Gong Z Abstract Acute liver failure (ALF) is often accompanied by dynamic and functional disorders of mitochondria in hepatocytes. The histone deacetylase 6 inhibitor...
Wed Jun 24, 2020 15:14
Traumatic brain injury (TBI) is one of the major health problems worldwide that causes death or permanent disability through primary and secondary damages in the brain. TBI causes primary brain damage and activates glial cells and immune and inflammatory cells, including mast cells in the brain associated with neuroinflammatory responses that cause secondary brain damage. Though the survival rate and the neurological deficiencies have shown significant improvement in many TBI patients with newer...
Wed Jun 24, 2020 12:50
Inflammation is a key regulator in the progression of atherosclerosis (AS) which extremely affects people’s health. Secoisolariciresinol diglucoside (SDG), a plant lignan, is relevant to angiogenesis and cardioprotection against ischemia-reperfusion injury and improves vascular disorders. However, the effect of SDG on cardiovascular disorder is not clear. In the present study, we aimed to investigate the effects of SDG on lipopolysaccharide- (LPS-) stimulated Human Umbilical Vein Endothelial Cells...
Wed Jun 24, 2020 12:50
The immunopathology of chlamydial diseases is exacerbated by a broad-spectrum of inflammatory mediators, which we reported are inhibited by IL-10 in macrophages. However, the chlamydial protein moiety that induces the inflammatory mediators and the mechanisms by which IL-10 inhibits them are unknown. We hypothesized that Chlamydia major outer membrane protein (MOMP) mediates its disease pathogenesis, and the suppressor of cytokine signaling (SOCS)1 and SOCS3 proteins are mediators of the IL-10 inhibitory...
Wed Jun 24, 2020 12:35
Related Articles Cutaneous side effects of hydroxychloroquine in health care workers in a COVID referral hospital - implications for clinical practice. J Dermatolog Treat. 2020 Jun 22;:1-3 Authors: Sardana K, Mathachan SR, Deepak D, Khurana A, Sinha S Abstract The utility of hydroxychloroquine for the prophylaxis and treatment of alarmingly rising COVID-19 infection has been widely explored in several studies. However, its cutaneous adverse...
Wed Jun 24, 2020 15:09
Abstract Nasal polyposis (NP) are benign lesion of nasal cavity, affecting up to 1–4% of population. It is known to have up to 70% recurrence rate. The underlying pathophysiology is still undetermined. Recent literatures have thrown light on the viral aetiology for NP. To our knowledge this is the first Indian study done, that aims to evaluate the prevalence of Human papillomavirus (HPV) in NP. It was a prospective case control study done among 40 individuals with NP and 40 healthy...
Wed Jun 24, 2020 03:00
Abstract Allergic Rhinitis is one of the most commonly recognised rhinitis globally. Though its not a life threatening entity but it is associated with severe impairment of quality of life along with substantial financial burden on patient. There has been a substantial rise in number of patients of allergic rhinitis over years and researchers worldwide have also found low levels of vitamin D in patients of allergic rhinitis. It is a randomised control trial with 87 subjects divided...
Wed Jun 24, 2020 03:00
Abstract The present study was undertaken to identify the complimentary role of high resolution ultrasonography and fine needle aspiration cytology (FNAC) in diagnosis of thyroid gland swelling pathology, also determine sensitivity, specificity and accuracy of both USG and FNAC and correlate it with histopathology report. Total 75 cases of thyroid swellings were evaluated in detail by taking history, doing clinical examination, USG, FNAC and histopathology. USG findings were correlated...
Wed Jun 24, 2020 03:00
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