Related ArticlesCan Lung US Help Critical Care Clinicians in the Early Diagnosis of Novel Coronavirus (COVID-19) Pneumonia? Radiology. 2020 Mar 13;:200847 Authors: Poggiali E, Dacrema A, Bastoni D, Tinelli V, Demichele E, Mateo Ramos P, Marcianò T, Silva M, Vercelli A, Magnacavallo A PMID: 32167853 [PubMed - as supplied by publisher]
Sat Mar 14, 2020 12:26
Related ArticlesLetter to the Editor. Posterior transdural approach for cervical stenosis caused by retroflexion of anterior elements in a child with Pfeiffer syndrome. J Neurosurg Pediatr. 2020 Mar 13;:1-2 Authors: Prolo LM, Bass DI, Bauer JM, Browd SR PMID: 32168492 [PubMed - as supplied by publisher]
Sat Mar 14, 2020 12:24
Related ArticlesPigmented epithelioid melanocytoma: a rare lytic bone lesion involving intradural extension and subtotal resection in a 14-month-old girl. J Neurosurg Pediatr. 2020 Mar 13;:1-4 Authors: D'Souza P, Barr EK, Thirumala SD, Jacob R, Nagy L Abstract Pigmented epithelioid melanocytomas (PEMs) are low-grade, intermediate-type borderline melanocytic tumors with limited metastatic potential. To date, PEMs have been treated via gross-total resections....
Sat Mar 14, 2020 12:24
Related ArticlesA long-term evaluation of a training program on breaking bad news in pediatric neurosurgery: a pilot study. J Neurosurg Pediatr. 2020 Mar 13;:1-9 Authors: Zanello M, Baugnon T, Roux A, Di Rocco F Abstract OBJECTIVE: Breaking bad news is a difficult task in medical practice. Several breaking-bad-news training programs have been proposed. However, long-term results of such training have rarely been investigated. The aim of this study was...
Sat Mar 14, 2020 12:24
Abstract In this work, we examined by DSC protein denaturation heat capacity profiles for two body fluids, cerebrospinal fluid (CSF) and blood plasma obtained from brain tumor (mainly glioblastoma) patients and healthy volunteers. We observed large distinctions between the heat capacity profiles of CSF and blood plasma, although their protein compositions are believed to have much in common. A prominent, previously unreported CSF feature was the existence of a pre-denaturation...
Sat Mar 14, 2020 02:00
Related ArticlesEvaluation and Management of Children with Obstructive Sleep Apnea Syndrome. Lung. 2020 Mar 12;: Authors: Bitners AC, Arens R Abstract Obstructive sleep apnea syndrome (OSAS) is a common pediatric disorder characterized by recurrent events of partial or complete upper airway obstruction during sleep which result in abnormal ventilation and sleep pattern. OSAS in children is associated with neurobehavioral deficits and cardiovascular morbidity...
Sat Mar 14, 2020 12:20
Related ArticlesAssociation Between Risk of Obstructive Sleep Apnea and Cerebrovascular Reactivity in Stroke Patients. J Am Heart Assoc. 2020 Mar 17;9(6):e015313 Authors: Castello-Branco RC, Cerqueira-Silva T, Andrade AL, Gonçalves BMM, Pereira CB, Felix IF, Santos LSB, Porto LM, Marques MEL, Catto MB, Oliveira MA, de Sousa PRSP, Muiños PJR, Maia RM, Schnitman S, Oliveira-Filho J Abstract Background Obstructive sleep apnea (OSA) is present in 60% to...
Sat Mar 14, 2020 12:20
Related ArticlesImaging features of pharyngeal hairy polyps in infants. Oral Radiol. 2020 Mar 11;: Authors: Sheng M, Mi Y, Gao F, Liang J, Zhou H Abstract BACKGROUND: Hairy polyps are the most common congenital deformity of the oral-nasopharynx/oral cavity in infants, which may lead to severe complications in the newborns. However, few studies have been published with respect to their radiological features, and most are case reports. OBJECTIVE:...
Fri Mar 13, 2020 12:06
Related ArticlesEffect of mouth closure on upper airway obstruction in patients with obstructive sleep apnoea exhibiting mouth breathing: a drug-induced sleep endoscopy study. Eur Arch Otorhinolaryngol. 2020 Mar 11;: Authors: Koo SK, Park GH, Koh TK, Jung SH, Lee HB, Ji CL Abstract PURPOSE: Snoring and obstructive sleep apnoea (OSA) exhibit multifactorial aetiologies; mouth breathing increases airway obstruction and upper respiratory tract resistance....
Fri Mar 13, 2020 12:06
Related ArticlesDifferential gene expression of ASUN, NEMF, PTPRC and DHX29: Candidate biomarkers for diagnosis of active and latent tuberculosis. Infect Disord Drug Targets. 2020 Mar 13;: Authors: Mamishi S, Pourakbari B, Sadeghi RH, Marjani M, Mahmoudi S Abstract INTRODUCTION: Tuberculosis (TB) remains as one of the most important infectious causes of death through the world. A wide range of technologies have been used for the diagnosis of TB. However,...
Sat Mar 14, 2020 12:12
Related ArticlesConcurrent Methicillin-resistant Staphylococcus aureus septicemia and thyroid abscess in a young male with Dengue. Infect Disord Drug Targets. 2020 Mar 12;: Authors: Meena DS, Kumar D, Bohra GK, Garg MK, Midha N, Yadav T, Yadav P Abstract BACKGROUND: Dengue fever is an arthropod-borne viral infection with a very high incidence in Southeast Asia. Most patients present with self-limiting febrile illness, while some patients may develop...
Sat Mar 14, 2020 12:12
Related ArticlesMonoclonal antibodies against infectious microbes: so long and too little! Infect Disord Drug Targets. 2020 Mar 12;: Authors: Raj G, Priyadarshini R, Murugesan S, Adhimoolam M Abstract Monoclonal antibodies (mAbs) as alternatives or more often as complementary to the conventional antimicrobials are being developed for the management of infectious conditions for the past two decades. These pharmacotherapeutic strategies are inevitable...
Sat Mar 14, 2020 12:12
Publication date: Available online 13 March 2020Source: Allergology InternationalAuthor(s): Takashi Matsuda, Hideyasu Yamada, Norihito Hida, Taisuke Nakaizumi, Emmi Yamada, Hiroaki Satoh, Nobuyuki Hizawa
Sat Mar 14, 2020 12:09
Abstract We aimed to verify the expression status and diagnostic significance of IDH1 in NSCLC, especially during early stages. Serum IDH1 levels were measured by ELISA. A total of 1223 participants [660 patients with NSCLC, 276 healthy controls (HCs), 95 patients with benign pulmonary conditions (BPCs), 135 patients with other cancers (OCs) and 57 samples with interfering factors] were divided into a training cohort and a validation cohort according to three testing centers. The IDH1 concentrations...
Sat Mar 14, 2020 11:45
Abstract Human leukocyte antigen (HLA) class Ⅰ molecules play a central role in anticancer immunity, but their prognostic value in oral squamous cell carcinoma (OSCC) remains unclear. We examined HLA class Ⅰ expression in two distinct tumor compartments, namely, the tumor center and invasive front, and evaluated the association between its expression pattern and histopathological status in 137 cases with OSCC. HLA class Ⅰ expression was graded semi‐quantitatively as high, low, and negative. At...
Sat Mar 14, 2020 11:45
Abstract NF‐kappa B (NF‐κB) pathway plays a pivotal role in tumor progression and chemoresistance, and its inhibition has been shown to suppress tumor growth in a variety of preclinical models. Recently, we have succeeded in synthesizing a water‐soluble injectable type of curcumin β‐D‐glucuronide (CMG), which is converted into a free‐form of curcumin by β‐glucuronidase in vivo. Herein, we aimed to clarify the efficacy, safety, and pharmacokinetics of CMG in a xenograft mouse model. First, we confirmed...
Fri Mar 13, 2020 12:38
Treatment of infections by Pseudomonas aeruginosa forming biofilms after antimicrobial testing on planktonic bacteria can result in substantial failure. Therefore, we offer a robust and simple experimental platfo...
Fri Mar 13, 2020 02:00
Abstract Purpose The aim of this study is to examine the sphenoid sinus morphology and variations in patients with cleft lip and palate (CLP) on cone-beam computed tomography (CBCT) images, and to compare them with healthy controls. Methods CBCT images of 54 patients (28 males and 26 females,) with CLP and 54 age- and gender-matched healthy...
Sat Mar 14, 2020 11:10
Abstract Purpose This study aims to investigate the safety and effectiveness of videolaryngoscope-assisted coblation of epiglottic cysts (VACECs) under general anesthesia. Methods Twenty-eight consecutive patients with epiglottic cysts (ECs), underwent VACECs in this prospective clinical series from January 2015 to March 2019. The pre-operative...
Sat Mar 14, 2020 11:10
Abstract Objective To characterize the audiological findings of a sample of patients with osteogenesis imperfecta (OI) in southern Brazil. Methods This was a cross-sectional, observational, quantitative study. Research was carried out at a hospital which is considered to offer benchmark treatment for patients with OI in southern Brazil. Seventy-seven...
Sat Mar 14, 2020 11:10
Abstract Purpose To evaluate optimal stimulation parameters with regard to discomfort and tolerability for transcutaneous electrostimulation of facial muscles in healthy participants and patients with postparetic facial synkinesis. Methods Two prospective studies were performed. First, single pulse monophasic stimulation with rectangular pulses...
Sat Mar 14, 2020 11:10
Abstract Purpose Cardiovascular risk factors, including metabolic syndrome (MetS) components, were reported as possible risk factors of sudden sensorineural hearing loss (SSNHL). The objective of this study was to evaluate the relationship between MetS (and its components) and SSNHL. Methods Eighty-one SSNHL patients and 243 sex-, aged-matched...
Sat Mar 14, 2020 11:10
Abstract Purpose Intravenous lidocaine infusion has been used for postoperative analgesia in many surgical procedures in recent years. The aim of this randomized, double-blind study was to investigate the postoperative analgesic efficacy of perioperative intravenous lidocaine infusion in patients undergoing septorhinoplasty surgery. Materials and methods ...
Sat Mar 14, 2020 11:10
Abstract Introduction Semi-occluded vocal tract exercises, such as water resistance therapy (WRT), are widely used in voice therapy. However, the potential positive effects of such a therapy on vocal fold oscillation patterns in patients indicating a need for phonomicrosurgery have not yet been explored. The presented study aims to analyze the effect of WRT in patients suffering from vocal fold mass lesions. ...
Sat Mar 14, 2020 02:00
Abstract Purpose Reasons for delayed presentation in cancer are reported as patient or professional delays. Studies have examined patient demographic factors associated with presentation delay, but it is currently unknown why patients feel they delayed presenting. Methods Questionnaire study of consecutive patients attending an urgent suspicion of cancer...
Fri Mar 13, 2020 02:00
Abstract Background Poorly differentiated thyroid cancer (PDTC) is biologically more aggressive. Surgery remains the mainstay of treatment. The utility of radioactive iodine (RAI) after surgery is unclear. Methods In this retrospective study, patients treated between Jan 2012 and Dec 2017 were included. The demographic, clinical and treatment-related details,...
Fri Mar 13, 2020 02:00
Abstract Purpose E-learning provides a flexible and effective approach to learning and is increasingly used in otorhinolaryngology (ORL). We developed a national theoretical e-learning course for ORL trainees and describe our experiences with implementation as well as piloting the e-learning course. Methods E-learning course content was developed as structured...
Fri Mar 13, 2020 02:00
Abstract Purpose Epistaxis that is refractory to conservative management can be treated with endoscopic sphenopalatine artery ligation (ESPAL). Although rare, ethmoidal artery (EA) bleeding can be a cause of rebleeding after successful ESPAL. EA bleeding is diagnosed by angiography and can also be identified during surgical exploration. However, since the angiographic embolization of the EA is contraindicated, surgical hemostasis is mandatory....
Fri Mar 13, 2020 02:00
Abstract Introduction The aetiology, management and prognosis of idiopathic Sdden Sensorineural Hearing Loss (ISSNHL) are still uncertain despite adequate investigation. Objective We conducted the present study to investigate the possible relationship between the neutrophil-to-lymphocyte ratio (NLR) and the prognosis of ISSNHL based on PSM. ...
Fri Mar 13, 2020 02:00
Abstract Purpose Limited approach septoplasty (LAS) follows the principle of respecting nasal structures and aims to minimize complications while ensuring proper nasal respiratory function. LAS is only applicable to selected cases of septal deviation. The present study aimed to: (1) compare short- and mid-term complications in two consecutive series of patients with the same type of septal deviation treated with LAS or classical septoplasty;...
Fri Mar 13, 2020 02:00
Abstract Purpose Nasopharyngeal cancer is a type of malignancy originating from the epithelial cells lining the nasopharynx. In genetic and environmental factors, infection with Epstein–Barr virus is one of the particular factors held accountable for the etiopathogenesis. Human papillomavirus has been associated with cervical, anogenital, and oropharyngeal cancers. The aim of the present study is to demonstrate the presence and incidence...
Fri Mar 13, 2020 02:00
Sat Mar 14, 2020 10:39
Abstract Spontaneously regressing infantile haemangiomas and aggressive angiosarcomas are vascular tumours with excessive angiogenesis. When analysing haemangiomas and angiosarcomas immunohistochemically with respect to their chaperone profiles we found that angiosarcomas have significantly elevated protein levels of BiP and PERK with concomitant attenuated IRE1α levels while haemangioma tissue exhibits the same pattern as embryonal skin tissue. We show that BiP is essential for the maintenance...
Sat Mar 14, 2020 10:38
Abstract This study aimed to validate the Oral Health-related Self-Efficacy Scale for Patients with Cancer (OSEC), comprised of 17 questions (five factors). To this end, a sample of 203 cancer patients was recruited (August 2018–April 2019) followed by a random subsampling for test-retest reliability. Concurrent validity was tested by correlating scores with the Self-efficacy Scale for Advanced Cancer (SEAC), discriminant validity was tested by comparing high OSEC to low OSEC...
Sat Mar 14, 2020 02:00
Abstract Complementary and alternative medicine (CAM) usage amongst cancer patients is high globally and in Australia. CAM use in cancer care has the ability to increase chemotherapy toxicity or cause sub-therapy due to altered metabolism as well as increase a patient’s bleeding risk. Furthering these risks, people with cancer are largely obtaining their CAM use information from non-evidence-based sources. This study aimed to determine whether the implementation of a CAM education...
Fri Mar 13, 2020 02:00
Background De‐intensified treatment strategies for early human papillomavirus–positive (HPV+) oropharynx cancer (OPC) rely on selecting patients with an excellent prognosis. The criterion for enrollment in current de‐intensification trials is ≤10 pack‐years. More nuance to the pack‐year criteria may expand enrollment, improve patient outcomes, and prevent overtreatment. It was hypothesized that patients with more than 10 pack‐years may experience favorable outcomes if smoking cessation has been...
Sat Mar 14, 2020 10:18
Background Inpatient supportive care programs often target patients with advanced solid tumors. To the authors' knowledge, few studies to date have characterized symptom burden in hospitalized patients with potentially curable cancers. The objective of the current study was to compare symptom burden, palliative care consultation, and readmission rates in hospitalized patients by cancer type and treatment intent. Methods The authors conducted a single‐center study of hospitalized patients...
Sat Mar 14, 2020 10:18
Background The objective of this study was to evaluate the outcomes of patients with high‐grade glioma who received treatment with particle radiotherapy. Methods Between June 2015 and October 2018, 50 consecutive and nonselected patients with glioblastoma multiforme (n = 34) or anaplastic glioma (n = 16) were treated at the Shanghai Proton and Heavy Ion Center. Twenty‐four patients received proton radiotherapy (at a dose of 60 gray‐equivalents in 30 daily fractions), and 26 patients received...
Sat Mar 14, 2020 10:18
Current Anthropology, Ahead of Print.
Fri Mar 13, 2020 10:50
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