Antibiotics, Vol. 9, Pages 438: Gram-negative Organisms from Patients with Community-Acquired Urinary Tract Infections and Associated Risk Factors for Antimicrobial Resistance: A Single-Center Retrospective Observational Study in Japan Antibiotics doi: 10.3390/antibiotics9080438 Authors: Naoki Kanda Hideki Hashimoto Tomohiro Sonoo Hiromu Naraba Yuji Takahashi Kensuke Nakamura Shuji Hatakeyama A specific antibiogram is necessary for the empiric antibiotic treatment of...
Thu Jul 23, 2020 03:00
Antibiotics, Vol. 9, Pages 439: Prescription of Levofloxacin and Moxifloxacin in Select Hospitals in Uganda: A Pilot Study to Assess Guideline Concordance Antibiotics doi: 10.3390/antibiotics9080439 Authors: Victoria Nambasa Helen B. Ndagije Allan Serwanga Leonard Manirakiza Joanitah Atuhaire Diana Nakitto Ronald Kiguba Albert Figueras Background: In Uganda, national tuberculosis (TB) treatment guidelines were revised to include the newer generation fluoroquinolones...
Thu Jul 23, 2020 03:00
Antibiotics, Vol. 9, Pages 436: Best Helicobacter pylori Eradication Strategy in the Era of Antibiotic Resistance Antibiotics doi: 10.3390/antibiotics9080436 Authors: Su Young Kim Jun-Won Chung Antibiotic resistance is the major reason for Helicobacter pylori treatment failure, and the increasing frequency of antibiotic resistance is a challenge for clinicians. Resistance to clarithromycin and metronidazole is a particular problem. The standard triple therapy (proton pump inhibitor,...
Thu Jul 23, 2020 03:00
Antibiotics, Vol. 9, Pages 437: Day 10 Post-Prescription Audit Optimizes Antibiotic Therapy in Patients with Bloodstream Infections Antibiotics doi: 10.3390/antibiotics9080437 Authors: Rita Murri Claudia Palazzolo Francesca Giovannenze Francesco Taccari Marta Camici Teresa Spanu Brunella Posteraro Maurizio Sanguinetti Roberto Cauda Massimo Fantoni This study aimed to investigate the clinical and organizational impact of an active re-evaluation (on day 10) of...
Thu Jul 23, 2020 03:00
Antioxidants, Vol. 9, Pages 655: Hybrid Heme Peroxidases from Rice Blast Fungus Magnaporthe oryzae Involved in Defence against Oxidative Stress Antioxidants doi: 10.3390/antiox9080655 Authors: Marcel Zámocký Anna Kamlárová Daniel Maresch Katarína Chovanová Jana Harichová Paul G. Furtmüller Hybrid B heme peroxidases are recently discovered unique oxidoreductases present solely in the fungal kingdom. We have investigated two typical representatives from Magnaporthe oryzae—one...
Thu Jul 23, 2020 03:00
Antioxidants, Vol. 9, Pages 654: Molecular Assessment of Epiretinal Membrane: Activated Microglia, Oxidative Stress and Inflammation Antioxidants doi: 10.3390/antiox9080654 Authors: Sushma Vishwakarma Rishikesh Kumar Gupta Saumya Jakati Mudit Tyagi Rajeev Reddy Pappuru Keith Reddig Gregory Hendricks Michael R. Volkert Hemant Khanna Jay Chhablani Inderjeet Kaur Fibrocellular membrane or epiretinal membrane (ERM) forms on the surface of the inner limiting...
Thu Jul 23, 2020 03:00
Antioxidants, Vol. 9, Pages 653: Oxidative Stress and Obesity- and Type 2 Diabetes-Induced Heart Failure Antioxidants doi: 10.3390/antiox9080653 Authors: Luc Demaison Obesity is a risk factor for the development of type 2 diabetes (T2D), which is associated with cardiovascular diseases [...]
Thu Jul 23, 2020 03:00
Antioxidants, Vol. 9, Pages 652: Endogenous Carbon Monoxide Signaling Modulates Mitochondrial Function and Intracellular Glucose Utilization: Impact of the Heme Oxygenase Substrate Hemin Antioxidants doi: 10.3390/antiox9080652 Authors: David Stucki Julia Steinhausen Philipp Westhoff Heide Krahl Dominik Brilhaus Annika Massenberg Andreas P. M. Weber Andreas S. Reichert Peter Brenneisen Wilhelm Stahl Stress-inducible heme oxygenase-1 (HO-1) catalyzes the oxidative...
Thu Jul 23, 2020 03:00
Atmosphere, Vol. 11, Pages 777: Characteristics of Orographic Rain Drop-Size Distribution at Cherrapunji, Northeast India Atmosphere doi: 10.3390/atmos11080777 Authors: Fumie Murata Toru Terao Kaustav Chakravarty Hiambok Jones Syiemlieh Laitpharlang Cajee The rain drop size distribution (DSD) at Cherrapunji, Northeast India was observed by a laser optical disdrometer Parsivel 2 from May to October 2017; this town is known for the world’s heaviest orographic...
Thu Jul 23, 2020 03:00
Atmosphere, Vol. 11, Pages 778: The Relationship of Energy and CO2 Emissions with GDP per Capita in Colombia Atmosphere doi: 10.3390/atmos11080778 Authors: Lourdes Isabel Patiño Emilio Padilla Vicent Alcántara Josep Lluís Raymond We analyze the relationship of CO2 emissions per capita and primary energy per capita with gross domestic product (GDP) per capita and other relevant variables in Colombia for the period 1971–2017. Two partial adjustment models are estimated...
Thu Jul 23, 2020 03:00
Atmosphere, Vol. 11, Pages 779: Groundwater Vulnerability in the Piedmont Region under Climate Change Atmosphere doi: 10.3390/atmos11080779 Authors: Nistor Groundwater vulnerability has increased in recent decades due to several factors, but mainly due to climate change. In this study, we applied a complex approach to determine groundwater vulnerability at a regional scale in the Piedmont region including high-resolution climate models. Aquifers, terrain model, climate data, land cover,...
Thu Jul 23, 2020 03:00
Atmosphere, Vol. 11, Pages 776: Local Climate Zone Classification Scheme Can Also Indicate Local-Scale Urban Ventilation Performance: An Evidence-Based Study Atmosphere doi: 10.3390/atmos11080776 Authors: Ziqi Zhao Lidu Shen Liguang Li Hongbo Wang Bao-Jie He Studies on urban ventilation indicate that urban ventilation performance is highly dependent on urban morphology. Some studies have linked local-scale urban ventilation performance with the local climate zone (LCZ) that...
Thu Jul 23, 2020 03:00
Atmosphere, Vol. 11, Pages 775: A Weighting Scheme in A Multi-Model Ensemble for Bias-Corrected Climate Simulation Atmosphere doi: 10.3390/atmos11080775 Authors: Yonggwan Shin Youngsaeng Lee Jeong-Soo Park A model weighting scheme is important in multi-model climate ensembles for projecting future changes. The climate model output typically needs to be bias corrected before it can be used. When a bias-correction (BC) is applied, equal model weights are usually derived because some...
Thu Jul 23, 2020 03:00
Beverages, Vol. 6, Pages 46: B-Vitamins Determination in Donkey Milk Beverages doi: 10.3390/beverages6030046 Authors: Silvia Vincenzetti Stefania Pucciarelli Giuseppe Santini Yulia Klimanova Valeria Polzonetti Paolo Polidori Background: Donkey milk is used in infant nutrition for the treatment of children affected by cow’s milk protein allergy, thanks to its hypo-allergenicity, mainly due to its protein profile, which is very close to that of human milk. Furthermore,...
Thu Jul 23, 2020 03:00
Biology, Vol. 9, Pages 189: Phylogenetic Diversity of Trichoderma Strains and Their Antagonistic Potential against Soil-Borne Pathogens under Stress Conditions Biology doi: 10.3390/biology9080189 Authors: Omar A. Hewedy Khalid S. Abdel Lateif Mahmoud F. Seleiman Ashwag Shami Fawziah M. Albarakaty Rasha M. El-Meihy Trichoderma species are known as excellent biocontrol agents against soil-borne pathogens that cause considerable crop losses. Eight strains of Trichoderma were...
Thu Jul 23, 2020 03:00
Biology, Vol. 9, Pages 187: The Intersection of DNA Damage Response and Ferroptosis—A Rationale for Combination Therapeutics Biology doi: 10.3390/biology9080187 Authors: Po-Han Chen Watson Hua-Sheng Tseng Jen-Tsan Chi Ferroptosis is a novel form of iron-dependent cell death characterized by lipid peroxidation. While the importance and disease relevance of ferroptosis are gaining recognition, much remains unknown about its interaction with other biological processes and pathways....
Thu Jul 23, 2020 03:00
Biology, Vol. 9, Pages 188: Piggybacking on Classical Import and Other Non-Classical Mechanisms of Nuclear Import Appear Highly Prevalent within the Human Proteome Biology doi: 10.3390/biology9080188 Authors: Tanner M. Tessier Katelyn M. MacNeil Joe S. Mymryk One of the most conserved cellular pathways among eukaryotes is the extensively studied classical protein nuclear import pathway mediated by importin-α. Classical nuclear localization signals (cNLSs) are recognized...
Thu Jul 23, 2020 03:00
Biology, Vol. 9, Pages 186: Biochemical Profile of the Soybean Seed Embryonic Axis and Its Changes during Accelerated Aging Biology doi: 10.3390/biology9080186 Authors: Luciano Antônio Ebone Andréia Caverzan Diógenes Cecchin Silveira Luciano de Oliveira Siqueira Nadia Canali Lângaro José Luís Trevizan Chiomento Geraldo Chavarria Seed deterioration is an important topic in plant science, as the majority of cultivated species use seeds as their means of propagation; however,...
Thu Jul 23, 2020 03:00
Biomedicines, Vol. 8, Pages 239: Reference Gene Validation in the Brain Regions of Young Rats after Pentylenetetrazole-Induced Seizures Biomedicines doi: 10.3390/biomedicines8080239 Authors: Alexander P. Schwarz Anna A. Kovalenko Daria A. Malygina Tatiana Y. Postnikova Olga E. Zubareva Aleksey V. Zaitsev Reverse transcription followed by quantitative polymerase chain reaction (qRT-PCR) is a powerful and commonly used tool for gene expression analysis. It requires the right...
Thu Jul 23, 2020 03:00
Biomedicines, Vol. 8, Pages 241: Synthesis and Biomedical Potential of Azapeptide Modulators of the Cluster of Differentiation 36 Receptor (CD36) Biomedicines doi: 10.3390/biomedicines8080241 Authors: Caroline Proulx Jinqiang Zhang David Sabatino Sylvain Chemtob Huy Ong William D. Lubell The innovative development of azapeptide analogues of growth hormone releasing peptide-6 (GHRP-6) has produced selective modulators of the cluster of differentiation 36 receptor (CD36)....
Thu Jul 23, 2020 03:00
Biomedicines, Vol. 8, Pages 238: Gender-Related Differences in Trimethylamine and Oxidative Blood Biomarkers in Cardiovascular Disease Patients Biomedicines doi: 10.3390/biomedicines8080238 Authors: Laura Bordoni Donatella Fedeli Marco Piangerelli Iwona Pelikant-Malecka Adrianna Radulska Joanna J. Samulak Angelika K. Sawicka Lukasz Lewicki Leszek Kalinowski Robert A. Olek Rosita Gabbianelli Gender differences in the burden of cardiovascular disease (CVD)...
Thu Jul 23, 2020 03:00
Biomedicines, Vol. 8, Pages 237: Evidence-Based Medicine in Oncology: Commercial Versus Patient Benefit Biomedicines doi: 10.3390/biomedicines8080237 Authors: Volker Schirrmacher Tobias Sprenger Wilfried Stuecker Stefaan W. Van Gool At times of personalized and individualized medicine the concept of randomized- controlled clinical trials (RCTs) is being questioned. This review article explains principles of evidence-based medicine in oncology and shows an example of how evidence...
Thu Jul 23, 2020 03:00
Biomedicines, Vol. 8, Pages 240: N-acetylcysteine Provides Cytoprotection in Murine Oligodendrocytes through Heme Oxygenase-1 Activity Biomedicines doi: 10.3390/biomedicines8080240 Authors: Jie Zhou Marcia R. Terluk Lisa Basso Usha R. Mishra Paul J. Orchard James C. Cloyd Henning Schröder Reena V. Kartha Oligodendrocytic injury by oxidative stress can lead to demyelination, contributing to neurodegeneration. We investigated the mechanisms by which an antioxidant,...
Thu Jul 23, 2020 03:00
Biomolecules, Vol. 10, Pages 1096: The Interaction of Bovine β-Lactoglobulin with Caffeic Acid: from Binding Mechanisms to Functional Complexes Biomolecules doi: 10.3390/biom10081096 Authors: Nicoleta Stănciuc Gabriela Râpeanu Gabriela Elena Bahrim Iuliana Aprodu In this study, the interaction of native and transglutaminase (Tgase) cross-linked β-lactoglobulin (β-LG) with caffeic acid (CA) was examined, aiming to obtain functional composites. Knowledge on the...
Thu Jul 23, 2020 03:00
Biomolecules, Vol. 10, Pages 1095: Glutenin and Gliadin, a Piece in the Puzzle of their Structural Properties in the Cell Described through Monte Carlo Simulations Biomolecules doi: 10.3390/biom10081095 Authors: Joel Markgren Mikael Hedenqvist Faiza Rasheed Marie Skepö Eva Johansson Gluten protein crosslinking is a predetermined process where specific intra- and intermolecular disulfide bonds differ depending on the protein and cysteine motif. In this article, all-atom Monte...
Thu Jul 23, 2020 03:00
Biomolecules, Vol. 10, Pages 1094: 4-(N-Alkyl- and -Acyl-amino)-1,2,4-triazole-3-thione Analogs as Metallo-β-Lactamase Inhibitors: Impact of 4-Linker on Potency and Spectrum of Inhibition Biomolecules doi: 10.3390/biom10081094 Authors: Laurent Gavara Federica Verdirosa Alice Legru Paola Sandra Mercuri Lionel Nauton Laurent Sevaille Georges Feller Dorothée Berthomieu Filomena Sannio Francesca Marcoccia Silvia Tanfoni Filomena De Luca Nohad Gresh Moreno...
Thu Jul 23, 2020 03:00
Biosensors, Vol. 10, Pages 83: Sniffing Out Urinary Tract Infection—Diagnosis Based on Volatile Organic Compounds and Smell Profile Biosensors doi: 10.3390/bios10080083 Authors: Valentin-Mihai Dospinescu Akira Tiele James A. Covington Current available methods for the clinical diagnosis of urinary tract infection (UTI) rely on a urine dipstick test or culturing of pathogens. The dipstick test is rapid (available in 1–2 min), but has a low positive predictive value, while...
Thu Jul 23, 2020 03:00
Biosensors, Vol. 10, Pages 82: Towards Bacteria Counting in DI Water of Several Microliters or Growing Suspension Using Impedance Biochips Biosensors doi: 10.3390/bios10080082 Authors: Mahdi Kiani Astrid Tannert Nan Du Uwe Hübner Ilona Skorupa Danilo Bürger Xianyue Zhao Daniel Blaschke Lars Rebohle Charaf Cherkouk Ute Neugebauer Oliver G. Schmidt Heidemarie Schmidt We counted bacterial cells of E. coli strain K12 in several-microliter DI water or in...
Thu Jul 23, 2020 03:00
Biosensors, Vol. 10, Pages 81: Development of an Electrochemical Immunosensor for Specific Detection of Visceral Leishmaniasis Using Gold-Modified Screen-Printed Carbon Electrodes Biosensors doi: 10.3390/bios10080081 Authors: Beatriz R. Martins Yanne O. Barbosa Cristhianne M. R. Andrade Loren Q. Pereira Guilherme F. Simão Carlo J. de Oliveira Dalmo Correia Robson T. S. Oliveira Marcos V. da Silva Anielle C. A. Silva Noelio O. Dantas Virmondes Rodrigues Rodrigo...
Thu Jul 23, 2020 03:00
Brain Sciences, Vol. 10, Pages 473: Facial Emotion Recognition in Children and Adolescents with Specific Learning Disorder Brain Sciences doi: 10.3390/brainsci10080473 Authors: Francesca Felicia Operto Grazia Maria Giovanna Pastorino Maria Stellato Lucia Morcaldi Luigi Vetri Marco Carotenuto Andrea Viggiano Giangennaro Coppola (1) Background: Some recent studies suggest that children and adolescents with different neurodevelopmental disorders perform worse in emotions...
Thu Jul 23, 2020 03:00
Brain Sciences, Vol. 10, Pages 474: Individual Differences in Infants’ Temperament Affect Face Processing Brain Sciences doi: 10.3390/brainsci10080474 Authors: Jennifer L. Rennels Andrea J. Kayl Kirsty M. Kulhanek Infants show an advantage in processing female and familiar race faces, but the effect sizes are often small, suggesting individual differences in their discrimination abilities. This research assessed whether differences in 6–10-month-olds’ temperament...
Thu Jul 23, 2020 03:00
Brain Sciences, Vol. 10, Pages 475: Effects of Phosphatidylserine Source of Docosahexaenoic Acid on Cerebellar Development in Preterm Pigs Brain Sciences doi: 10.3390/brainsci10080475 Authors: Daniel Chizhikov Randal K. Buddington Igor Y. Iskusnykh Preterm birth, a major contributor to infant mortality and morbidity, impairs development of the cerebellum, the brain region involved in cognitive processing and motor function. Previously, we showed that at term-equivalent age, preterm...
Thu Jul 23, 2020 03:00
Brain Sciences, Vol. 10, Pages 472: Adolescent Intermittent Ethanol Exposure Effects on Kappa Opioid Receptor Mediated Dopamine Transmission: Sex and Age of Exposure Matter Brain Sciences doi: 10.3390/brainsci10080472 Authors: Mary B. Spodnick Raymond T. Amirault Trevor T. Towner Elena I. Varlinskaya Linda P. Spear Anushree N. Karkhanis Underage alcohol drinking increases the risk of developing alcohol use disorder (AUD). In rodents, adolescent ethanol exposure augments...
Thu Jul 23, 2020 03:00
Cancers, Vol. 12, Pages 2022: Inhibition of the Lysophosphatidylinositol Transporter ABCC1 Reduces Prostate Cancer Cell Growth and Sensitizes to Chemotherapy Cancers doi: 10.3390/cancers12082022 Authors: Aikaterini Emmanouilidi Ilaria Casari Begum Gokcen Akkaya Tania Maffucci Luc Furic Federica Guffanti Massimo Broggini Xi Chen Yulia Y. Maxuitenko Adam B. Keeton Gary A. Piazza Kenneth J. Linton Marco Falasca Expression of ATP-binding cassette (ABC)...
Thu Jul 23, 2020 03:00
Cancers, Vol. 12, Pages 2023: Correction: Gualdani, R.; et al. Store-Operated Calcium Entry Contributes to Cisplatin-Induced Cell Death in Non-Small Cell Lung Carcinoma. Cancers 2019, 11, 430 Cancers doi: 10.3390/cancers12082023 Authors: Roberta Gualdani Marie de Clippele Ikram Ratbi Philippe Gailly Nicolas Tajeddine The authors wish to make the following corrections to this paper [...]
Thu Jul 23, 2020 03:00
Cancers, Vol. 12, Pages 2021: Gold Nanoparticles as a Potent Radiosensitizer: A Transdisciplinary Approach from Physics to Patient Cancers doi: 10.3390/cancers12082021 Authors: Penninckx Heuskin Michiels Lucas Over the last decade, a growing interest in the improvement of radiation therapies has led to the development of gold-based nanomaterials as radiosensitizer. Although the radiosensitization effect was initially attributed to a dose enhancement mechanism, an increasing...
Thu Jul 23, 2020 03:00
Cancers, Vol. 12, Pages 2019: Impact of Hypoxia on Carbon Ion Therapy in Glioblastoma Cells: Modulation by LET and Hypoxia-Dependent Genes Cancers doi: 10.3390/cancers12082019 Authors: Samuel Valable Aurélie N. Gérault Gaëlle Lambert Marine M. Leblond Clément Anfray Jérôme Toutain Karim Bordji Edwige Petit Myriam Bernaudin Elodie A. Pérès Tumor hypoxia is known to limit the efficacy of ionizing radiations, a concept called oxygen enhancement ratio (OER). OER...
Thu Jul 23, 2020 03:00
Cancers, Vol. 12, Pages 2018: Prognostic Value of Immune Environment Analysis in Small Bowel Adenocarcinomas with Verified Mutational Landscape and Predisposing Conditions Cancers doi: 10.3390/cancers12082018 Authors: Erkki-Ville Wirta Säde Szeto Ulrika Hänninen Maarit Ahtiainen Jan Böhm Jukka-Pekka Mecklin Lauri A. Aaltonen Toni T. Seppälä Background: Small bowel adenocarcinoma (SBA) is a rare yet insidious cancer with poor survival. The abundance of tumour-infiltrating...
Thu Jul 23, 2020 03:00
Cancers, Vol. 12, Pages 2020: PET Imaging Agents (FES, FFNP, and FDHT) for Estrogen, Androgen, and Progesterone Receptors to Improve Management of Breast and Prostate Cancers by Functional Imaging Cancers doi: 10.3390/cancers12082020 Authors: John A. Katzenellenbogen Many breast and prostate cancers are driven by the action of steroid hormones on their cognate receptors in primary tumors and in metastases, and endocrine therapies that inhibit hormone production or block the action of...
Thu Jul 23, 2020 03:00
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